目的:通过研究Embrace Wet Bond Resi n Cement树脂水门汀用于粘结折裂牙的临床疗效,旨在为保存修复折裂牙建立一套实用而简便的治疗模式以提高患牙的保存率。方法:选择35例(36颗)折裂牙作为研究对象,先打开患牙的近远中接触点,预成带...目的:通过研究Embrace Wet Bond Resi n Cement树脂水门汀用于粘结折裂牙的临床疗效,旨在为保存修复折裂牙建立一套实用而简便的治疗模式以提高患牙的保存率。方法:选择35例(36颗)折裂牙作为研究对象,先打开患牙的近远中接触点,预成带坏固定后降合,在裂隙俩侧制备双鸠尾洞型,将Embrace Wet Bond Resi n Cement树脂水门汀注入折裂面并及时复位、光照、充填,观察2周后去带环行全冠修复。结果:经6～12月复查:3例折裂牙因反复出现牙周脓肿拔除,2例咀嚼略有不适感,成功率91%。结论:用Embrace Wet Bond Resi n Cement树脂水门丁保存修复折裂牙,弥补了传统粘结法的缺陷,使患牙得以保存,也简便了临床医生的操作。展开更多
A resin-modified glass-ionomer cement (RMGIC) was studied from a computational point of view. We suggest terpolymer formation by reaction of fixation through a combination of acrylic acid (AA), itaconic acid (IA) and ...A resin-modified glass-ionomer cement (RMGIC) was studied from a computational point of view. We suggest terpolymer formation by reaction of fixation through a combination of acrylic acid (AA), itaconic acid (IA) and an aminoacid derivative (AAD) in different positions. We found that AAD-AA-IA is thermodynamically more stable, but AA-IA-AAD is the combination which can react with glycidyl methacrylate (GM) to form a grafted polymer with two pendant methacrylate groups which can be used later in the process of light-curing. A RMGIC contains a glass powder of calcium-fluoroaluminosilicate acting as the source of cross linking, and for this reason, we have optimized two intramolecular Al3+ tricarboxylate complexes (salt-bridges) formed from the most stable grafted polymers. A possible reaction mechanism for the addition of (GM) to copolymer is proposed.展开更多
In vitro responses of human primary pulp cells (HPCs) and 3T3 mouse fibroblasts to six contempo-rary commercial dental restoratives were evaluated using the WST-1 assay. The results show that Fuji II is not cytotoxic ...In vitro responses of human primary pulp cells (HPCs) and 3T3 mouse fibroblasts to six contempo-rary commercial dental restoratives were evaluated using the WST-1 assay. The results show that Fuji II is not cytotoxic to both cells. Fuji II LC is not cyto-toxic to HPCs but cytotoxic to 3T3 cells, indicating that 3T3 cells are more vulnerable to 2-hydroxyethyl methacrylate (HEMA) than HPCs. Vitremer is very cytotoxic probably due to having diphenyliodonium chloride and HEMA in it. Z100 is very cytotoxic probably due to having triethylene glycol dimethacry-late (TEGDMA) in it. P60 is cytotoxic but less cyto-toxic than Z100 probably due to no TEGDMA in it. Durelon is the most cytotoxic among the six materials studied probably due to the high cytotoxicity of zinc ions. Additionally, the cytotoxcity of the tested mate-rials was found to be dose-dependent.展开更多
In vitro cytotoxicity of six contemporary commercial dental filling restoratives on human dental primary cells, pulp cells (HPCs) and human gingival fibroblasts (HGFs), were tested using WST-1 assay. Continuous 3T3 mo...In vitro cytotoxicity of six contemporary commercial dental filling restoratives on human dental primary cells, pulp cells (HPCs) and human gingival fibroblasts (HGFs), were tested using WST-1 assay. Continuous 3T3 mouse fibroblast cell lines were used for comparison. The results show that conventional glass-ionomer cement (GIC) Fuji II is not cytotoxic to all the cells. Resin-modified GIC (RMGIC) Fuji II LC is not cytotoxic to both HPCs and HGFs but cytotoxic to 3T3 cells. RMGIC Vitremer and resin composite Z100 are very cytotoxic to all the cells. Resin composite P60 is cytotoxic but much less cytotoxic than Z100. Polycarboxylate cement Durelon is the most cytotoxic among the six tested materials. It was found that continuous 3T3 cell lines were more vulnerable to leachable cytotoxic components than primary HPCs and HGFs. It was also found that the cytotoxcity of the tested materials was dose-dependent.展开更多
目的采用扫描电镜观察涂用脱敏剂的牙本质的微观特征,评价脱敏剂对树脂粘接剂粘接强度的影响。方法对离体正畸牙进行常规牙体预备,分别涂用Gluma系统处理剂、Single Bond 2脱敏剂、BisBlockTM脱敏剂,用扫描电镜观察牙本质表面和剖面的...目的采用扫描电镜观察涂用脱敏剂的牙本质的微观特征,评价脱敏剂对树脂粘接剂粘接强度的影响。方法对离体正畸牙进行常规牙体预备,分别涂用Gluma系统处理剂、Single Bond 2脱敏剂、BisBlockTM脱敏剂,用扫描电镜观察牙本质表面和剖面的微观特征。用树脂粘接剂把铸件粘接到经脱敏剂处理的牙本质表面,测定样本的剪切强度,用SPSS 13.0软件进行统计学分析。结果Gluma组牙本质小管开口几乎堵塞;Single Bond 2组牙本质表面形成厚的树脂层;BisBlockTM组牙本质小管开口部分堵塞。BisBlockTM组剪切强度最大,为(13.04±2.76)MPa,与对照组相比,其差异有统计学意义(P<0.05)。结论Gluma系统处理剂、Single Bond 2脱敏剂、BisBlockTM脱敏剂能够堵塞牙本质小管开口。BisBlockTM脱敏剂可以增强树脂粘接剂的粘接强度。展开更多
目的:为了提高氧化锆修复体的粘接强度,使用热酸蚀法处理氧化锆的粘接表面,并比较处理后用两种常用树脂粘接剂粘接到牙釉质表面的剪切粘接强度。方法:分别制作光滑的牙釉质粘接面和氧化锆粘接面,氧化锆表面分别接受空白处理、喷砂处理...目的:为了提高氧化锆修复体的粘接强度,使用热酸蚀法处理氧化锆的粘接表面,并比较处理后用两种常用树脂粘接剂粘接到牙釉质表面的剪切粘接强度。方法:分别制作光滑的牙釉质粘接面和氧化锆粘接面,氧化锆表面分别接受空白处理、喷砂处理、热酸蚀表面处理。电子显微镜观察处理后的氧化锆表面形态,使用Super Bond C&B和Panavia F 2.0树脂粘接剂进行粘接。使用万能力学试验机进行剪切实验,十字头加载速度为1 mm/s,并使用单因素方差分析对数据进行统计学分析以比较热酸蚀处理对氧化锆和树脂粘接强度的影响。结果:Super Bond组氧化锆剪切粘接强度分别为:空白处理(23.37±3.94)MPa、喷砂处理(25.95±3.05)MPa、热酸蚀处理(34.52±1.8)MPa;Panavia组氧化锆剪切粘接强度分别为:空白处理(12.91±3.33)MPa、喷砂处理(14.00±3.28)MPa、热酸蚀处理(18.47±4.16)MPa。两种粘接剂组中热酸蚀处理后的氧化锆试件剪切粘接强度明显高于空白处理和喷砂处理,差异具有统计学意义(P<0.01)。结论:热酸蚀处理可以有效提升氧化锆表面和树脂的粘接强度。展开更多
目的:研究一步法和两步法通用型粘接剂与不同双固化树脂水门汀匹配使用时,光固化模式对牙本质粘接强度的影响。方法:选用一步法通用型粘接剂Single Bond Universal(SBU)和两步法通用型粘接剂Opti Bond Versa(VSA)作为研究对象,以一步法...目的:研究一步法和两步法通用型粘接剂与不同双固化树脂水门汀匹配使用时,光固化模式对牙本质粘接强度的影响。方法:选用一步法通用型粘接剂Single Bond Universal(SBU)和两步法通用型粘接剂Opti Bond Versa(VSA)作为研究对象,以一步法自酸蚀粘接剂Opti Bond All in One(AIO)和两步法自酸蚀粘接剂Clearfil SE Bond(SEB)作为对照,同时选择Rely X Ultimate(RLX)和Nexus 3 Universal(NX3)作为不同的双固化树脂水门汀。收集新鲜无龋磨牙80颗,切除冠部釉质,暴露牙本质平面。根据粘接剂种类、粘接剂是否进行光固化和水门汀种类的不同组合分为16组,每组随机5颗。按照说明使用各组粘接剂,光固化(10 s)或者不进行光固化后,在粘接剂上方放置树脂水门汀厚度为1 mm,光照20 s(650 m W/cm^2),然后在水门汀上方分层填压复合树脂并固化(厚度5 mm)。水中储存24 h后,使用慢速切片机制备横截面积1 mm×1 mm的条形树脂-水门汀-牙本质样本,测定微拉伸粘接强度。结果:SBU光固化后与RLX和NX3联合使用,粘接强度[(35.45±7.04)MPa和(26.84±10.39)MPa]显著高于未光固化组[(17.93±8.93)MPa和(10.07±5.89)MPa,P<0.001]。SBU在相同光固化模式下,与RLX匹配使用的粘接强度显著高于与NX3匹配使用的粘接强度(P<0.05)。与对照AIO相比,SBU光固化后与RLX匹配使用时的粘接强度高于AIO组[(35.45±7.04)MPa vs.(24.86±8.42)MPa,P<0.05],而未光固化下SBU的粘接强度低于AIO组[(17.93±8.93)MPa vs.(22.28±7.57)MPa,P<0.05]。两步法通用型粘接剂VSA与对照粘接剂SEB在不同的光照模式及联合使用不同的水门汀各组之间的粘接强度(25.98~32.24 MPa)差异没有统计学意义(P>0.05)。结论:一步法通用型粘接剂的固化模式以及双固化水门汀的种类对于水门汀与牙本质的粘接强度均有一定的程度的影响。对于两步法通用型粘接系统,固化模式以及水门汀的种类对于水门汀与牙本质的粘接强度无显著影响。展开更多
文摘目的:通过研究Embrace Wet Bond Resi n Cement树脂水门汀用于粘结折裂牙的临床疗效,旨在为保存修复折裂牙建立一套实用而简便的治疗模式以提高患牙的保存率。方法:选择35例(36颗)折裂牙作为研究对象,先打开患牙的近远中接触点,预成带坏固定后降合,在裂隙俩侧制备双鸠尾洞型,将Embrace Wet Bond Resi n Cement树脂水门汀注入折裂面并及时复位、光照、充填,观察2周后去带环行全冠修复。结果:经6～12月复查:3例折裂牙因反复出现牙周脓肿拔除,2例咀嚼略有不适感,成功率91%。结论:用Embrace Wet Bond Resi n Cement树脂水门丁保存修复折裂牙,弥补了传统粘结法的缺陷,使患牙得以保存,也简便了临床医生的操作。
文摘A resin-modified glass-ionomer cement (RMGIC) was studied from a computational point of view. We suggest terpolymer formation by reaction of fixation through a combination of acrylic acid (AA), itaconic acid (IA) and an aminoacid derivative (AAD) in different positions. We found that AAD-AA-IA is thermodynamically more stable, but AA-IA-AAD is the combination which can react with glycidyl methacrylate (GM) to form a grafted polymer with two pendant methacrylate groups which can be used later in the process of light-curing. A RMGIC contains a glass powder of calcium-fluoroaluminosilicate acting as the source of cross linking, and for this reason, we have optimized two intramolecular Al3+ tricarboxylate complexes (salt-bridges) formed from the most stable grafted polymers. A possible reaction mechanism for the addition of (GM) to copolymer is proposed.
文摘In vitro responses of human primary pulp cells (HPCs) and 3T3 mouse fibroblasts to six contempo-rary commercial dental restoratives were evaluated using the WST-1 assay. The results show that Fuji II is not cytotoxic to both cells. Fuji II LC is not cyto-toxic to HPCs but cytotoxic to 3T3 cells, indicating that 3T3 cells are more vulnerable to 2-hydroxyethyl methacrylate (HEMA) than HPCs. Vitremer is very cytotoxic probably due to having diphenyliodonium chloride and HEMA in it. Z100 is very cytotoxic probably due to having triethylene glycol dimethacry-late (TEGDMA) in it. P60 is cytotoxic but less cyto-toxic than Z100 probably due to no TEGDMA in it. Durelon is the most cytotoxic among the six materials studied probably due to the high cytotoxicity of zinc ions. Additionally, the cytotoxcity of the tested mate-rials was found to be dose-dependent.
文摘In vitro cytotoxicity of six contemporary commercial dental filling restoratives on human dental primary cells, pulp cells (HPCs) and human gingival fibroblasts (HGFs), were tested using WST-1 assay. Continuous 3T3 mouse fibroblast cell lines were used for comparison. The results show that conventional glass-ionomer cement (GIC) Fuji II is not cytotoxic to all the cells. Resin-modified GIC (RMGIC) Fuji II LC is not cytotoxic to both HPCs and HGFs but cytotoxic to 3T3 cells. RMGIC Vitremer and resin composite Z100 are very cytotoxic to all the cells. Resin composite P60 is cytotoxic but much less cytotoxic than Z100. Polycarboxylate cement Durelon is the most cytotoxic among the six tested materials. It was found that continuous 3T3 cell lines were more vulnerable to leachable cytotoxic components than primary HPCs and HGFs. It was also found that the cytotoxcity of the tested materials was dose-dependent.
文摘目的采用扫描电镜观察涂用脱敏剂的牙本质的微观特征,评价脱敏剂对树脂粘接剂粘接强度的影响。方法对离体正畸牙进行常规牙体预备,分别涂用Gluma系统处理剂、Single Bond 2脱敏剂、BisBlockTM脱敏剂,用扫描电镜观察牙本质表面和剖面的微观特征。用树脂粘接剂把铸件粘接到经脱敏剂处理的牙本质表面,测定样本的剪切强度,用SPSS 13.0软件进行统计学分析。结果Gluma组牙本质小管开口几乎堵塞;Single Bond 2组牙本质表面形成厚的树脂层;BisBlockTM组牙本质小管开口部分堵塞。BisBlockTM组剪切强度最大,为(13.04±2.76)MPa,与对照组相比,其差异有统计学意义(P<0.05)。结论Gluma系统处理剂、Single Bond 2脱敏剂、BisBlockTM脱敏剂能够堵塞牙本质小管开口。BisBlockTM脱敏剂可以增强树脂粘接剂的粘接强度。
文摘目的:为了提高氧化锆修复体的粘接强度,使用热酸蚀法处理氧化锆的粘接表面,并比较处理后用两种常用树脂粘接剂粘接到牙釉质表面的剪切粘接强度。方法:分别制作光滑的牙釉质粘接面和氧化锆粘接面,氧化锆表面分别接受空白处理、喷砂处理、热酸蚀表面处理。电子显微镜观察处理后的氧化锆表面形态,使用Super Bond C&B和Panavia F 2.0树脂粘接剂进行粘接。使用万能力学试验机进行剪切实验,十字头加载速度为1 mm/s,并使用单因素方差分析对数据进行统计学分析以比较热酸蚀处理对氧化锆和树脂粘接强度的影响。结果:Super Bond组氧化锆剪切粘接强度分别为:空白处理(23.37±3.94)MPa、喷砂处理(25.95±3.05)MPa、热酸蚀处理(34.52±1.8)MPa;Panavia组氧化锆剪切粘接强度分别为:空白处理(12.91±3.33)MPa、喷砂处理(14.00±3.28)MPa、热酸蚀处理(18.47±4.16)MPa。两种粘接剂组中热酸蚀处理后的氧化锆试件剪切粘接强度明显高于空白处理和喷砂处理,差异具有统计学意义(P<0.01)。结论:热酸蚀处理可以有效提升氧化锆表面和树脂的粘接强度。
文摘目的:研究一步法和两步法通用型粘接剂与不同双固化树脂水门汀匹配使用时,光固化模式对牙本质粘接强度的影响。方法:选用一步法通用型粘接剂Single Bond Universal(SBU)和两步法通用型粘接剂Opti Bond Versa(VSA)作为研究对象,以一步法自酸蚀粘接剂Opti Bond All in One(AIO)和两步法自酸蚀粘接剂Clearfil SE Bond(SEB)作为对照,同时选择Rely X Ultimate(RLX)和Nexus 3 Universal(NX3)作为不同的双固化树脂水门汀。收集新鲜无龋磨牙80颗,切除冠部釉质,暴露牙本质平面。根据粘接剂种类、粘接剂是否进行光固化和水门汀种类的不同组合分为16组,每组随机5颗。按照说明使用各组粘接剂,光固化(10 s)或者不进行光固化后,在粘接剂上方放置树脂水门汀厚度为1 mm,光照20 s(650 m W/cm^2),然后在水门汀上方分层填压复合树脂并固化(厚度5 mm)。水中储存24 h后,使用慢速切片机制备横截面积1 mm×1 mm的条形树脂-水门汀-牙本质样本,测定微拉伸粘接强度。结果:SBU光固化后与RLX和NX3联合使用,粘接强度[(35.45±7.04)MPa和(26.84±10.39)MPa]显著高于未光固化组[(17.93±8.93)MPa和(10.07±5.89)MPa,P<0.001]。SBU在相同光固化模式下,与RLX匹配使用的粘接强度显著高于与NX3匹配使用的粘接强度(P<0.05)。与对照AIO相比,SBU光固化后与RLX匹配使用时的粘接强度高于AIO组[(35.45±7.04)MPa vs.(24.86±8.42)MPa,P<0.05],而未光固化下SBU的粘接强度低于AIO组[(17.93±8.93)MPa vs.(22.28±7.57)MPa,P<0.05]。两步法通用型粘接剂VSA与对照粘接剂SEB在不同的光照模式及联合使用不同的水门汀各组之间的粘接强度(25.98~32.24 MPa)差异没有统计学意义(P>0.05)。结论:一步法通用型粘接剂的固化模式以及双固化水门汀的种类对于水门汀与牙本质的粘接强度均有一定的程度的影响。对于两步法通用型粘接系统,固化模式以及水门汀的种类对于水门汀与牙本质的粘接强度无显著影响。
