BACKGROUND Phosphoglyceride crystal deposition disease(PCDD)is a rare acquired disease in which phospholipid crystals deposit in bone and soft tissue long after surgery,trauma,or repeated injections.CASE SUMMARY A 60-...BACKGROUND Phosphoglyceride crystal deposition disease(PCDD)is a rare acquired disease in which phospholipid crystals deposit in bone and soft tissue long after surgery,trauma,or repeated injections.CASE SUMMARY A 60-year-old-woman was referred to our department because of multiple abdominal masses after open splenectomy for idiopathic thrombocytopenic purpura 29 years earlier.All the masses showed marked fluorodeoxyglucose(FDG)uptake on ^(18)F-fluorodeoxyglucose positron emission tomography(^(18)F-FDGPET)and were strongly suspected to be malignant tumors.Surgical biopsies were performed,and the abdominal masses were found to be aligned vertically,three in a row,along the tissue layers cut in the patient’s previous surgery.Pathological finding of the specimens showed foreign body granuloma consisting of histiocytes and multinucleated giant cells accumulating around needle-like crystals.The crystals were confirmed as phosphoglyceride by Raman spectroscopy,and PCDD was diagnosed.To our knowledge,this is the first report of PCDD diagnosed by Raman spectroscopy.CONCLUSION We made a definitive diagnosis of PCDD in a patient with multiple tumors showing marked FDG uptake on ^(18)F-FDG-PET by incisional biopsy and composition analysis using Raman spectroscopy,a method that has not previously been reported for the diagnosis of PCDD.展开更多
The western slope of the Songliao Basin is a gently dipping monoclinal slope featured by stratum overlap, gradual change of stratum inclination and limited fault development, which formed during basin depression inter...The western slope of the Songliao Basin is a gently dipping monoclinal slope featured by stratum overlap, gradual change of stratum inclination and limited fault development, which formed during basin depression interrupted by a tectonic inversion stage. Structure, sedimentation and reser- voir characteristics show that the development of the slope and its sand bodies＇ depositional genesis de- termined the types, distribution and evolution of traps. Up-dip wedge-out traps in distributary channels, lenticular traps in distal sand bars and sand sheets in the delta front are the main lithologic trap types and usually have thin reservoir beds, small areas, and are distributed in clusters and belts. The episode of tectonic inversion led to the formation of structural traps and combination traps. The combination traps are characterized by large numbers of thin oil-bearing beds occurring along fold belts. Matching axial directions of distributary channel sand bodies in delta fronts with channel morphology during the period between deposition of sand bodies and sealing by an unconformity above is the key to the search for large scale traps in a simple slope area.展开更多
文摘BACKGROUND Phosphoglyceride crystal deposition disease(PCDD)is a rare acquired disease in which phospholipid crystals deposit in bone and soft tissue long after surgery,trauma,or repeated injections.CASE SUMMARY A 60-year-old-woman was referred to our department because of multiple abdominal masses after open splenectomy for idiopathic thrombocytopenic purpura 29 years earlier.All the masses showed marked fluorodeoxyglucose(FDG)uptake on ^(18)F-fluorodeoxyglucose positron emission tomography(^(18)F-FDGPET)and were strongly suspected to be malignant tumors.Surgical biopsies were performed,and the abdominal masses were found to be aligned vertically,three in a row,along the tissue layers cut in the patient’s previous surgery.Pathological finding of the specimens showed foreign body granuloma consisting of histiocytes and multinucleated giant cells accumulating around needle-like crystals.The crystals were confirmed as phosphoglyceride by Raman spectroscopy,and PCDD was diagnosed.To our knowledge,this is the first report of PCDD diagnosed by Raman spectroscopy.CONCLUSION We made a definitive diagnosis of PCDD in a patient with multiple tumors showing marked FDG uptake on ^(18)F-FDG-PET by incisional biopsy and composition analysis using Raman spectroscopy,a method that has not previously been reported for the diagnosis of PCDD.
基金sponsored by the University Science Fund of China (No.292013124)
文摘The western slope of the Songliao Basin is a gently dipping monoclinal slope featured by stratum overlap, gradual change of stratum inclination and limited fault development, which formed during basin depression interrupted by a tectonic inversion stage. Structure, sedimentation and reser- voir characteristics show that the development of the slope and its sand bodies＇ depositional genesis de- termined the types, distribution and evolution of traps. Up-dip wedge-out traps in distributary channels, lenticular traps in distal sand bars and sand sheets in the delta front are the main lithologic trap types and usually have thin reservoir beds, small areas, and are distributed in clusters and belts. The episode of tectonic inversion led to the formation of structural traps and combination traps. The combination traps are characterized by large numbers of thin oil-bearing beds occurring along fold belts. Matching axial directions of distributary channel sand bodies in delta fronts with channel morphology during the period between deposition of sand bodies and sealing by an unconformity above is the key to the search for large scale traps in a simple slope area.
