BACKGROUND Bronchial asthma is closely related to the occurrence of attention-deficit hyperactivity disorder(ADHD)in children,which can easily have adverse effects on children’s learning and social interactions.Studi...BACKGROUND Bronchial asthma is closely related to the occurrence of attention-deficit hyperactivity disorder(ADHD)in children,which can easily have adverse effects on children’s learning and social interactions.Studies have shown that childhood asthma can increase the risk of ADHD and the core symptoms of ADHD.Compared with children with ADHD alone,children with asthma and ADHD are more likely to show high levels of hyperactivity,hyperactive-impulsive and other externalizing behaviors and anxiety in clinical practice and have more symptoms of somatization and emotional internalization.AIM To explore the relationship between ADHD in children and bronchial asthma and to analyze its influencing factors.METHODS This retrospective cohort study was conducted at Dongying People's Hospital from September 2018 to August 2023.Children diagnosed with ADHD at this hospital were selected as the ADHD group,while healthy children without ADHD who underwent physical examinations during the same period served as the control group.Clinical and parental data were collected for all participating children,and multivariate logistic regression analysis was employed to identify risk factors for comorbid asthma in children with ADHD.RESULTSSignificant differences were detected between the ADHD group and the control group in terms of family history ofasthma and allergic diseases, maternal complications during pregnancy, maternal use of asthma and allergymedications during pregnancy, maternal anxiety and depression during pregnancy, and parental relationshipstatus (P < 0.05). Out of the 183 children in the ADHD group, 25 had comorbid asthma, resulting in a comorbidityrate of 13.66% (25/183), compared to the comorbidity rate of 2.91% (16/549) among the 549 children in the controlgroup. The difference in the asthma comorbidity rate between the two groups was statistically significant (P <0.05). The results of the multivariate logistic regression analysis indicated that family history of asthma and allergicdiseases, maternal complications during pregnancy, maternal use of asthma and allergy medications duringpregnancy, maternal anxiety and depression during pregnancy, and parental relationship status are independentrisk factors increasing the risk of comorbid asthma in children with ADHD (P < 0.05).CONCLUSIONChildren with ADHD were more likely to have comorbid asthma than healthy control children were. A familyhistory of asthma, adverse maternal factors during pregnancy, and parental relationship status were identified asrisk factors influencing the comorbidity of asthma in children with ADHD. Clinically, targeted interventions basedon these factors can be implemented to reduce the risk of comorbid asthma. This information is relevant for resultssections of abstracts in scientific articles.展开更多
目的对ICU转出患者心理障碍风险预测工具进行范围综述,为临床实践及相关研究提供参考。方法检索PubMed、Embase、Web of Science核心合集、中国知网、万方数据库、中国生物医学文献数据库中有关ICU转出患者心理障碍风险预测工具的研究,...目的对ICU转出患者心理障碍风险预测工具进行范围综述,为临床实践及相关研究提供参考。方法检索PubMed、Embase、Web of Science核心合集、中国知网、万方数据库、中国生物医学文献数据库中有关ICU转出患者心理障碍风险预测工具的研究,检索时限为建库至2021年7月11日。由2名研究者独立筛选文献和提取数据。采用预测模型偏倚风险评价工具及诊断准确性研究质量评价工具2对纳入文献进行偏倚风险及适用性评价。结果共纳入6篇文献,包括2项预测模型开发研究及4项预测工具效能验证研究。结论目前ICU转出患者心理障碍风险预测工具的预测效能较好,但纳入文献偏倚风险较高。未来应对现有的工具进行验证和完善,或构建低偏倚风险、高适用性的本土化预测工具。展开更多
文摘BACKGROUND Bronchial asthma is closely related to the occurrence of attention-deficit hyperactivity disorder(ADHD)in children,which can easily have adverse effects on children’s learning and social interactions.Studies have shown that childhood asthma can increase the risk of ADHD and the core symptoms of ADHD.Compared with children with ADHD alone,children with asthma and ADHD are more likely to show high levels of hyperactivity,hyperactive-impulsive and other externalizing behaviors and anxiety in clinical practice and have more symptoms of somatization and emotional internalization.AIM To explore the relationship between ADHD in children and bronchial asthma and to analyze its influencing factors.METHODS This retrospective cohort study was conducted at Dongying People's Hospital from September 2018 to August 2023.Children diagnosed with ADHD at this hospital were selected as the ADHD group,while healthy children without ADHD who underwent physical examinations during the same period served as the control group.Clinical and parental data were collected for all participating children,and multivariate logistic regression analysis was employed to identify risk factors for comorbid asthma in children with ADHD.RESULTSSignificant differences were detected between the ADHD group and the control group in terms of family history ofasthma and allergic diseases, maternal complications during pregnancy, maternal use of asthma and allergymedications during pregnancy, maternal anxiety and depression during pregnancy, and parental relationshipstatus (P < 0.05). Out of the 183 children in the ADHD group, 25 had comorbid asthma, resulting in a comorbidityrate of 13.66% (25/183), compared to the comorbidity rate of 2.91% (16/549) among the 549 children in the controlgroup. The difference in the asthma comorbidity rate between the two groups was statistically significant (P <0.05). The results of the multivariate logistic regression analysis indicated that family history of asthma and allergicdiseases, maternal complications during pregnancy, maternal use of asthma and allergy medications duringpregnancy, maternal anxiety and depression during pregnancy, and parental relationship status are independentrisk factors increasing the risk of comorbid asthma in children with ADHD (P < 0.05).CONCLUSIONChildren with ADHD were more likely to have comorbid asthma than healthy control children were. A familyhistory of asthma, adverse maternal factors during pregnancy, and parental relationship status were identified asrisk factors influencing the comorbidity of asthma in children with ADHD. Clinically, targeted interventions basedon these factors can be implemented to reduce the risk of comorbid asthma. This information is relevant for resultssections of abstracts in scientific articles.
文摘目的对ICU转出患者心理障碍风险预测工具进行范围综述,为临床实践及相关研究提供参考。方法检索PubMed、Embase、Web of Science核心合集、中国知网、万方数据库、中国生物医学文献数据库中有关ICU转出患者心理障碍风险预测工具的研究,检索时限为建库至2021年7月11日。由2名研究者独立筛选文献和提取数据。采用预测模型偏倚风险评价工具及诊断准确性研究质量评价工具2对纳入文献进行偏倚风险及适用性评价。结果共纳入6篇文献,包括2项预测模型开发研究及4项预测工具效能验证研究。结论目前ICU转出患者心理障碍风险预测工具的预测效能较好,但纳入文献偏倚风险较高。未来应对现有的工具进行验证和完善,或构建低偏倚风险、高适用性的本土化预测工具。
文摘目的探讨急性卒中患者躯体化症状的临床特征和影响因素。方法纳入急性卒中患者，应用90项症状清单（symptom checklist 90, SCL-90）躯体化因子部分评分将患者分为躯体化症状组（≥24分）和对照组（〈24分）。记录和比较其年龄、性别、经济水平、教育程度、基础疾病、汉密尔顿焦虑量表（Hamilton Anxiety Scale, HAMA）、汉密尔顿抑郁量表（Hamilton Depression Scale, HAMD）、大五人格量表评分、社会支持量表简体中文版评分、简易精神状态检查量表（Mini-Mental State Examination, MMSE）评分、美国国立卫生研究院卒中量表（National Institute of Health Stroke Scale, NIHSS）评分。结果共纳入急性卒中患者70例，其中33例（47.1%）存在躯体化症状。躯体化症状组人口统计学特征、受教育程度、家庭经济收入、职业、婚姻状况、独居情况、居住地、医疗费用支付方式以及社会支持评分均与对照组无显著差异，卒中类型、病灶侧别以及基线NIHSS、MMSE和大五人格量表评分亦与对照组无显著差异。躯体化症状组病灶部位与对照组存在显著差异（χ2＝0.161，P＝0.006）。神经心理学测验结果比较显示，躯体化症状组伴发焦虑状态的患者比例显著高于对照组（24.2%对5.4%；χ2＝5.055，P＝0.025），但伴发抑郁状态的患者比例无显著差异；剔除符合焦虑和抑郁标准的病例后，躯体化症状组（n＝25）HAMA[（8.08±3.12）分对（5.58±3.06）分；t＝－3.059，P＝0.003]和HAMD[（10.80±4.81）分对（7.73±3.88）分；t＝－2.694，P＝0.009]评分均显著高于对照组（n＝33）。躯体化症状组躯体化症状数量显著多于对照组（Z＝－5.817，P〈0.001），而且更易出现疼痛症状（97.0%对73.0%；χ2＝7.584，P＝0.006）。相关性分析显示，患者SCL-90躯体化因子12项得分与HAMA（r＝0.494，P〈0.001）和HAMD（r＝0.369，P＝0.002）评分存在显著正相关联系。多变量logistic回归分析显示，HAMA评分为卒中后躯体化症状的独立危险因素（优势比1.286，95%可信区间1.060～1.560；P＝0.011）。结论 急性卒中后躯体化症状发生率高，尤其是皮质卒中患者。卒中后躯体化患者易出现疼痛症状。卒中后焦虑和抑郁状态患者易伴发躯体化症状，HAMA评分是急性卒中后出现躯体化症状的独立危险因素。
