Treatment of Gray Hair in Vitiligo Patients by Direct Melanocytes Transplant Using Needling Micrografting and Dermabrasion Techniques

Background: Melanocytes transplant for treatment of vitiligo is a common therapy using different surgical procedures. But there was no interest in repigmentation of grayness of hair in the treated vitiliginous area. Objective: To do melanocytes transplant from donor area into the recipient vitiliginous area with associated gray hair. Patient and Methods: This is a case interventional study was done in Department of Dermatology/Baghdad Teaching Hospital from February 2011-March 2012. Eleven patients were enrolled in this study, six males and five females with vitiligo in association of gray hair. Their ages ranged from 8 - 35 years with a mean ±SD of 20.90 ± 7.006. Melanocytes transplant in patients with vitiligo using needling micrografting technique for twelve patches and direct melanocytes transplant from normal donor area into vitiliginous recipient area by dermabrasion technique for eleven patches. Dressing was applied and patients were seen every two weeks for the first month and monthly for one year. Results: Repigmentation of the vitiliginous area was started after two weeks and was obvious at one month that progressed over time. The repigmentation of hair appeared usually after few months and was obvious after four months and the repigmentation of gray hair was quicker in patients with micrografting technique than those with dermabrasion technique. The mean rate of repigmentation was 18.3% at six months and 37.5% at twelve months in micrografting technique while the mean rate of repigmentation was 9.15% at six months and 18.55 at twelve months in dermabrasion technique. Conclusions: Direct transplant of melanocytes from normal donor area into recipient vitiliginous area with associated white hair is an effective procedure to induce repigmentation of gray hair.

Direct Melanocytes Transplant from Normal Donor Area into Vitiliginous Recipient Area by Dermabrasion Technique

Background: Vitiligo is an autoimmune pigmentory disorder, that affects all age group that is treated by many medical treatments but some of them might need surgical therapy. Objective: To evaluate the dermabrasion technique in the treatment of vitiligo by direct transfer of melanocytes from the dermabraded normal donor area to the vitiliginous recipient area. Patients and Methods: This is a case interventional study was done in Department of Dermatology/Baghdad Teaching Hospital from February 2011-March 2012. Nine Patients with vitiligo were enrolled in this study with different clinical types of vitiligo including 5 segmental, 2 generalized and 2 localized. The donor and recipient areas were anesthetized at the same time with xylocain alone. Dermabrasion of recipient area was done first by manual abrader and left for few minutes until the oozing was stopped. Then the donor area was similarly dermabraded and the dermabraded tissue including the epidermis and superficial epidermis was immediately transferred into the recipient area and dressing was applied. Removal of the dressing was done after 10 - 14 days from the operative time. Follow up was done every 2 weeks in the first month then monthly for six months to record the result of implantation and repigmentation. Results: The re-pigmentation started one month after the operation as small macules and this increased gradually over time: the mean rate of re-pigmentation was 13% at 2 months, 27.8% at 4 months and 36.78% at 6 months. In addition, sun light exposure was applied to enhance re-pigmentation. The pigmentation was diffuse and not follicular in shape. Conclusion: Direct transfer of melanocytes from normal donor area into vitiliginous recipient area by dermabrasion technique was easy, rapid and non-costly and gave 36.78% mean rate of pigmentation at 6 months follow up and without complications.

Clinical observation of the effect of crystallitic dermabrasion on skin superficial scars

To oberserve the changes in histopathology and clinical effect after the treatment of superficial scars in human faces and exposed parts of human extremities with crystallitic dermabrasion.Methods The machine made in Italy can produce the high speed crystallite to the surface of the scar,resulting in the alveolate wounds.At the same time the crystolitic drill make the accidented scar smooth.Results Two thousands and five hundreds and thirty eight suffers were treated for 2～10 times.The appearance of the scars was improved.Six patients complicated with milium,Eleven got hypopigmentation,eight got hypomelanotation.Eighty percent patients of this groups got pigmentation after the treatment.This signs disappeared or improved after 2～6 months.Histopathology demonstrated the scar area became small,the fibroblasts increased remarkably and the collagenous fiber arranged regularly.The cells in the stratum spinosum proliferated actively.Conclusion Crystallitic dermabrasion is a simple and safe method for the treatment of skin superficial scars.5 refs,4 figs.

Insights on in-office scar revision and resurfacing procedures

Objective:Many facial plastic surgery procedures can be performed in an office-based setting,ranging from simple chemical peels to reconstructive surgeries to assist with scar revision.The aim of this review is to summarize the current state of facial plastics in-office surgical procedures,including scar revision,dermabrasion,lasers,and chemical peels.Methods:A literature review was conducted with the PubMed search engine with the following keywords:facial plastics,scar revision,dermabrasion,lasers,chemical peels,face,office,and outpatient.The literature was surveyed for relevance,with a focus on realistically which procedures were performed in a facial plastics surgery outpatient clinic.These were then used to compile a review of the current state of this field.Results and Conclusions:There are various scar revision procedures that can be performed in the office setting,including z-plasty,w-plasty,and geometric broken line closure techniques,as well as various nonmedical treatment options to improve the appearance of a scar.Dermabrasion can also be performed to assist with elevated scars.Various lasers are available to enhance cell turnover in the field of facial rejuvenation,scarring,and sun damage.Chemical peels are also available to assist with facial rejuvenation.With the appropriate counseling of the patient and medical staff,these can be safely performed in the office.

Treating traumatic tattoo by micro-incision

To design a micro incision operation for treating traumatic tattoo Methods With an 11 gauge blade, a micro incision was made on each side of the small tattoo spot and the tattoo skin was removed For a longer tattoo particle, a longer incision was needed The skin incision was sutured with 6-0 silk For a complex tattoo, dermabrasion could be used first to remove the superficial one so as to expose the deep one which was removed in the same way as mentioned above When there was a large number of tattoo particles, many operations were needed Results Fourteen patients were treated by this method with good to excellent result Conclusion Micro incision for treating traumatic tattoo is an effective method