Slope ecological protection technology is a form of slope protection with high ornamental and good economic value.At present,it is widely used in highways and urban streets’slope protection works.However,its use is n...Slope ecological protection technology is a form of slope protection with high ornamental and good economic value.At present,it is widely used in highways and urban streets’slope protection works.However,its use is not very common in mountain tourism highways;hence,it is necessary to implement strategies for mountain tourism highway slope ecological protection design to promote excellent development.展开更多
Highway is an important kind of infrastructure which the transportation sector depends on.The rationality of the interchange design between urban roads and expressways is related to the relieving of urban traffic pres...Highway is an important kind of infrastructure which the transportation sector depends on.The rationality of the interchange design between urban roads and expressways is related to the relieving of urban traffic pressure.Based on the status quo of interchange design between urban roads and expressways,this paper discusses the types and applications of interchange design,hoping to provide reference for the design and construction of highway projects and ensure the rationality of interchange design.展开更多
Under the new energy resource structure,electrocatalysts are key materials for the development of proton membrane fuel cells,electrolysis of aquatic hydrogen devices,and carbon dioxide reduction equipment,to address e...Under the new energy resource structure,electrocatalysts are key materials for the development of proton membrane fuel cells,electrolysis of aquatic hydrogen devices,and carbon dioxide reduction equipment,to address energy shortages and even environmental pollution issues.Although controlling the morphology or doping with heteroatoms for catalyst active centers have accelerated the reaction rate,it is difficult to solve the problems of multiple by-products,and poor stability of catalytic sites.From this,it will be seen that single regulation of metal active centers is difficult to comprehensively solve application problems.Orderly assembly and coordination of catalyst multi-hierarchy structures at the mesoscale above the nanometer level probably be more reasonable strategies,and numerous studies in thermal catalysis have supported this viewpoint.This article reviews the multi-hierarchy design of electrocatalyst active centers,high-energy supports,and peripheral structures in recent years,providing unconventional inspiration about electrocatalyst creation,which perhaps serves as a simple tutorial of electrocatalysis exploration for abecedarian.展开更多
Traditional CAD technique does not support the design processes such as function definition, conceptual design and preliminary design, which are most creative and play significant roles on the design quality. Because ...Traditional CAD technique does not support the design processes such as function definition, conceptual design and preliminary design, which are most creative and play significant roles on the design quality. Because scheme design has close relationship with product structure, performance and technology cost, it is important for applying the intelligent CAD of scheme design to improve the quality and competitive level of the product. The definition and function of welding positioner are discussed in this paper. The new definition of welding positioner extends the research scope of welding positioner to welding fixture and welding positioning motion mechanism. The design process of welding fixture and positioning motion system is described, and the cased based and knowledge based design strategy of welding positioner scheme design intelligent CAD is then put forward, which lays foundation for developing proto type system of welding positioner scheme design.展开更多
With the accelerated development and utilization of urban underground space,the underground space design of complex based on rail transit has attracted much attention.By sorting out the integration concept and constru...With the accelerated development and utilization of urban underground space,the underground space design of complex based on rail transit has attracted much attention.By sorting out the integration concept and constructing the logical framework of integrated design,the integrated design strategy is proposed from the aspects of function,transportation,space and environment on the urban scale,and the evaluation points of integrated design effect are put forward from the aspects of accessibility,coordination,openness and symbolism.展开更多
The memorial hall is an important place to learn red culture in China,which plays a positive role in carrying forward red culture and continuing revolutionary spirit.The outline of the “14^(th) Five-year” plan point...The memorial hall is an important place to learn red culture in China,which plays a positive role in carrying forward red culture and continuing revolutionary spirit.The outline of the “14^(th) Five-year” plan points out that “it should adhere to the integrated development,shape tourism with culture,highlight culture with tourism,and improve the system of integrated development of culture and tourism”.On this basis,it is proposed that the development of memorial halls in the new era needs the integration of culture and tourism.In this paper,the protection status of red culture of Hehan Detachment is investigated,and its existing problems are analyzed.The construction of Hehan Detachment Memorial Hall is taken as research object.The design strategy of the memorial hall is put forward,and rural red culture undertakings and the integrated development of culture and tourism industry are further established and improved.The research could provide a valuable reference for continuing red culture undertakings and innovating the development of culture and tourism industry at present.展开更多
Based on the functions and characteristics of the interchange collector-distributor lanes,with Harbin as an example,it is proposed in this paper that the local characteristics and traffic flow characteristics should b...Based on the functions and characteristics of the interchange collector-distributor lanes,with Harbin as an example,it is proposed in this paper that the local characteristics and traffic flow characteristics should be considered in the design of the interchange collector-distributor lanes,which includes the analysis of function,location,and many other aspects,in hopes to provide reference for the design of collector-distributor lanes in other regions of our country.展开更多
The interfacial structure plays an important role in the mechanical properties of magnesium matrix composite(MMCs)reinforced with graphene nanosheet(GNS)due to their poor wettability with the Mg matrix.An interface de...The interfacial structure plays an important role in the mechanical properties of magnesium matrix composite(MMCs)reinforced with graphene nanosheet(GNS)due to their poor wettability with the Mg matrix.An interface design strategy was proposed to form the semi-coherent interfacial structure with superior bonding strength.The lattice mismatch and interfacial bonding strength between Mg/rare earth oxide/carbon were utilized as key characteristics to evaluate the interfacial structure.Lanthanum oxide(La2O3)was selected as the intermediate candidate due to its low lattice mismatch and high interfacial bonding strength.To identify the interfacial structure of Mg/La2O3/graphene,first-principles calculations were conducted to calculate the ideal work of separation and electronic structure of the interfaces.Results demonstrated the presence of strong ionic and covalent interactions at the interface,which theoretically verified the strong interfacial bonding strength among Mg/La2O3/graphene interfaces.To experimentally validate the interface strength,MMCs with the interface structure of Mg/La2O3/GNS were developed.The formation of in-situ La2O3 led to the successful attainment of semi-coherent structures between Mg/La2O3 and La2O3/GNS,resulting in high strength and good ductility of the composite.Overall,this work proposes a new approach to interface design in MMCs with an enhancement of mechanical properties.展开更多
As a kind of large-scale physical energy storage,compressed air energy storage(CAES)plays an important role in the construction of more efficient energy system based on renewable energy in the future.Compared with tra...As a kind of large-scale physical energy storage,compressed air energy storage(CAES)plays an important role in the construction of more efficient energy system based on renewable energy in the future.Compared with traditional industrial compressors,the compressor of CAES has higher off-design performance requirements.From the perspective of design,it needs to pay attention not only to the performance of the design point,but also to the performance of all the stable working range.However,from the previous literature,no diagonal compressor was used in CAES which can meet the requirements,which also reflects the design program can be further improved.Therefore,this paper studies the design strategy of high efficient diagonal compressor for large-scale CAES,and gives the complete strategy algorithms used for different program modules.The pressure ratio,isentropic efficiency and stable working range are comprehensively considered.In the design process,the criteria for the key parameters of the diagonal flow angle of the diagonal compressor are given for the first time.The results show that the isentropic efficiency at the design point is 92.7%,the total pressure ratio is1.97,and the stable working range exceeds 20%,which meets the design requirements of the compressor for CAES and exceeds the overall performance of the previous compressors in the entire working range.展开更多
Multicolor fluorescent probes based on small organic molecules have the advantages of low cost, good biocompatibility, easily modifiable molecular structures and adjustable fluorescence performance. In addition, small...Multicolor fluorescent probes based on small organic molecules have the advantages of low cost, good biocompatibility, easily modifiable molecular structures and adjustable fluorescence performance. In addition, small molecule multicolor fluorescent probes generally undergo multi-site or multi-step reactions, which means that they can be used for the specific detection of structurally similar substances in complex bio-systems. In this review, we focus on the design and application of multicolor fluorescent probes based on small organic molecules: single fluorophores with multiple reaction sites, multiple fluorophores with single reaction sites, or multiple fluorophores with multiple reaction sites. Moreover, a design strategy for multicolor fluorescent probes and its application in biological imaging are also summarized, providing a systematic plan for future research on fluorescent probes functionalized by small organic molecules. It will also play an important role in the development of additional functions for small organic molecule fluorescent probes.展开更多
Since LiOsO_3 was discovered, obtaining easy-accessible polar metals for research and applications has been challenging. In this paper, we present a multilayer design strategy, which is configured as ferroelectric lay...Since LiOsO_3 was discovered, obtaining easy-accessible polar metals for research and applications has been challenging. In this paper, we present a multilayer design strategy, which is configured as ferroelectric layer/carrier reservoir layer/isolation layer/substrate, for obtaining polar metals by electrostatically doping a strained ferroelectric material in a more effective way. In the proposed configuration, both 1 unit-cell thick BaTiO_3 and PbTiO_3 exhibited considerable Ti off-centering with various strains,which should extend the applicability of ferroelectric-based polar metals in ultra-thin devices. Moreover, engineered by the compressive strain and the BaTiO_3 thickness, the design strategy effectively achieved polar metallicity and dimensionalitytunable electronic states associated with the modulation of highly anisotropic properties such as electrical and electronic thermal conductivity, which may be helpful for designing ultra-thin, ultrafast, and low-power switch devices.展开更多
Singlet fission(SF)has attracted much attention on account of its great potential for applications in high efficiency solar energy conversion.The major roadblock to realize this potential is rooted in the limited avai...Singlet fission(SF)has attracted much attention on account of its great potential for applications in high efficiency solar energy conversion.The major roadblock to realize this potential is rooted in the limited availability of practical SF material with strong absorption,suitable triplet energy level,an efficient SF process,and good chemical stability.Quinoidal structures feature an innate diradical character,which endows these skeletons with SF potential yet results in some structural instability.展开更多
Magnesium-based biomaterials(MBMs)are one of the most promising materials for tissue engineering due to their unique mechanical properties and excellent functional properties.This review describes the development,adva...Magnesium-based biomaterials(MBMs)are one of the most promising materials for tissue engineering due to their unique mechanical properties and excellent functional properties.This review describes the development,advantages,and challenges of MBMs for biomedical applications,especially for tissue repair and regeneration.The history of the use of MBMs from the beginning of the 20th century is traced,and the transformative advances in contemporary applications of MBMs in areas such as orthopedics and cardiovascular surgery are emphasized.The review also provides insight into the signaling pathways affected by MBMs,such as the PI3K/Akt and RANKL/RANK/OPG pathways,which are critical for osteogenesis and angiogenesis.The review advocates that future research should focus on optimizing alloy compositions,surface modification and exploring innovative technologies such as 3D printing to improve the efficacy of MBMs in complex tissue repair.The potential of MBMs to tissue engineering and regenerative medicine is significant,urging further exploration and interdisciplinary collaboration to maximize their therapeutic effects.展开更多
Rechargeable lithium-sulfur(Li-S)batteries,featuring high energy density,low cost,and environmental friendliness,have been dubbed as one of the most promising candidates to replace current commercial rechargeable Li-i...Rechargeable lithium-sulfur(Li-S)batteries,featuring high energy density,low cost,and environmental friendliness,have been dubbed as one of the most promising candidates to replace current commercial rechargeable Li-ion batteries.However,their practical deployment has long been plagued by the infamous“shuttle effect”of soluble Li polysulfides(LiPSs)and the rampant growth of Li dendrites.Therefore,it is important to specifically elucidate the solvation structure in the Li-S system and systematically summarize the feasibility strategies that can simultaneously suppress the shuttle effect and the growth of Li dendrites for practical applications.This review attempts to achieve this goal.In this review,we first introduce the importance of developing Li-S batteries and highlight the key challenges.Then,we revisit the working principles of Li-S batteries and underscore the fundamental understanding of LiPSs.Next,we summarize some representative characterization techniques and theoretical calculations applied to characterize the solvation structure of LiPSs.Afterward,we overview feasible designing strategies that can simultaneously suppress the shuttle effect of soluble LiPSs and the growth of Li dendrites.Finally,we conclude and propose personal insights and perspectives on the future development of Li-S batteries.We envisage that this timely review can provide some inspiration to build better Li-S batteries for promoting practical applications.展开更多
To enable further advanced study of Antarctica, a new station called Kunlun Station has been built by China in the Dome A region of the inland East Antarctic ice sheet. This paper describes the Antarctic station build...To enable further advanced study of Antarctica, a new station called Kunlun Station has been built by China in the Dome A region of the inland East Antarctic ice sheet. This paper describes the Antarctic station building design system that was developed with consideration of factors that may affect Kunlun Station, such as environment and climate, construction work and transport, environmental protection and energy conservation, psychological requirements and functional requirements. The design system included site selection, station planning, external building form, construction work, function and indoor environment, energy conservation, environmental protection, and material strategy. We also describe the experience acquired during the transportation and construction phases of Kunlun Station.展开更多
Transformation and innovation of assistance model promote the transition of urban social assistance building to multi-functional building. This paper, on the basis of analyzing complexity and peculiarity of urban soci...Transformation and innovation of assistance model promote the transition of urban social assistance building to multi-functional building. This paper, on the basis of analyzing complexity and peculiarity of urban social assistance building, as well as researches and practices of sustainable improvement of domestic architecture, proposed environmental, social and economic objectives of the sustainable improvement of urban social assistance building, and elaborated design strategies from the perspectives of site selection and its impact on environment, application, evaluation and utilization of ecological technologies, reform of old buildings, flexible internal layout of building and combination of routine use and disaster use design, so as to improve social benefits and social assessment of assistance buildings sustainably, and to balance humanistic concerns and social resource input.展开更多
Based on the characteristics of regional culture,the application strategies of regional cultural elements in the design of cultural and creative products were analyzed.The aim is to effectively combine cultural and cr...Based on the characteristics of regional culture,the application strategies of regional cultural elements in the design of cultural and creative products were analyzed.The aim is to effectively combine cultural and creative design with regional cultural elements to provide contemporary life with regional cultural and creative products,better serve modern needs,and enhance public awareness in the form of aesthetics.Firstly,the research status of regional culture and cultural and creative product design was summarized,and then the relationship between regional culture and product design was discussed from the aspects of appearance,material and craftsmanship.Afterwards,the value of regional cultural and creative product design was proposed,and the general strategies of regional cultural and creative products were further sorted out to make people feel the pleasure brought by the deep and strong regional culture.展开更多
Road traffic conditions can have an important impact on the economic development of various regions.Under the background of rapid social and economic development,more and more expressway construction projects are init...Road traffic conditions can have an important impact on the economic development of various regions.Under the background of rapid social and economic development,more and more expressway construction projects are initiated in various regions,including both new expressways and expansion of old expressways,and interchange design plays an important role.Scientific and reasonable interchange design can not only realize energy saving and low carbon footprint,but also be people-oriented and promote regional economic development.Therefore,this paper mainly analyzes the highway route and its interchange design strategy for reference.展开更多
Traditional modular design methods lead to product maintenance problems, because the module form of a system is created according to either the function requirements or the manufacturing considerations. For solving th...Traditional modular design methods lead to product maintenance problems, because the module form of a system is created according to either the function requirements or the manufacturing considerations. For solving these problems, a new modular design method is proposed with the considerations of not only the traditional function related attributes, but also the maintenance related ones. First, modularity parameters and modularity scenarios for product modularity are defined. Then the reliability and economic assessment models of product modularity strategies are formulated with the introduction of the effective working age of modules. A mathematical model used to evaluate the difference among the modules of the product so that the optimal module of the product can be established. After that, a multi-objective optimization problem based on metrics for preventive maintenance interval different degrees and preventive maintenance economics is formulated for modular optimization. Multi-objective GA is utilized to rapidly approximate the Pareto set of optimal modularity strategy trade-offs between preventive maintenance cost and preventive maintenance interval difference degree. Finally, a coordinate CNC boring machine is adopted to depict the process of product modularity. In addition, two factorial design experiments based on the modularity parameters are constructed and analyzed. These experiments investigate the impacts of these parameters on the optimal modularity strategies and the structure of module. The research proposes a new modular design method, which may help to improve the maintainability of product in modular design.展开更多
Although several research works in the literature have focused on studying the capabilities of additive manufacturing(AM) systems, few works have addressed the development of Design for Additive Manufacturing(DfAM) kn...Although several research works in the literature have focused on studying the capabilities of additive manufacturing(AM) systems, few works have addressed the development of Design for Additive Manufacturing(DfAM) knowledge,tools, rules, and methodologies, which has limited the penetration and impact of AM in industry. In this paper a comprehensive review of design and manufacturing strategies for Fused Deposition Modelling(FDM) is presented.Consequently, several DfAM strategies are proposed and analysed based on existing research works and the operation principles, materials, capabilities and limitations of the FDM process. These strategies have been divided into four main groups: geometry, quality, materials and sustainability. The implementation and practicality of the proposed DfAM is illustrated by three case studies. The new proposed DfAM strategies are intended to assist designers and manufacturers when making decisions to satisfy functional needs, while ensuring manufacturability in FDM systems.Moreover, many of these strategies can be applied or extended to other AM processes besides FDM.展开更多
文摘Slope ecological protection technology is a form of slope protection with high ornamental and good economic value.At present,it is widely used in highways and urban streets’slope protection works.However,its use is not very common in mountain tourism highways;hence,it is necessary to implement strategies for mountain tourism highway slope ecological protection design to promote excellent development.
文摘Highway is an important kind of infrastructure which the transportation sector depends on.The rationality of the interchange design between urban roads and expressways is related to the relieving of urban traffic pressure.Based on the status quo of interchange design between urban roads and expressways,this paper discusses the types and applications of interchange design,hoping to provide reference for the design and construction of highway projects and ensure the rationality of interchange design.
基金supported by the National Natural Science Foundation of China(91963206,21932004,21872067,22172072)the Ministry of Science and Technology of China(2021YFA1500301)。
文摘Under the new energy resource structure,electrocatalysts are key materials for the development of proton membrane fuel cells,electrolysis of aquatic hydrogen devices,and carbon dioxide reduction equipment,to address energy shortages and even environmental pollution issues.Although controlling the morphology or doping with heteroatoms for catalyst active centers have accelerated the reaction rate,it is difficult to solve the problems of multiple by-products,and poor stability of catalytic sites.From this,it will be seen that single regulation of metal active centers is difficult to comprehensively solve application problems.Orderly assembly and coordination of catalyst multi-hierarchy structures at the mesoscale above the nanometer level probably be more reasonable strategies,and numerous studies in thermal catalysis have supported this viewpoint.This article reviews the multi-hierarchy design of electrocatalyst active centers,high-energy supports,and peripheral structures in recent years,providing unconventional inspiration about electrocatalyst creation,which perhaps serves as a simple tutorial of electrocatalysis exploration for abecedarian.
文摘Traditional CAD technique does not support the design processes such as function definition, conceptual design and preliminary design, which are most creative and play significant roles on the design quality. Because scheme design has close relationship with product structure, performance and technology cost, it is important for applying the intelligent CAD of scheme design to improve the quality and competitive level of the product. The definition and function of welding positioner are discussed in this paper. The new definition of welding positioner extends the research scope of welding positioner to welding fixture and welding positioning motion mechanism. The design process of welding fixture and positioning motion system is described, and the cased based and knowledge based design strategy of welding positioner scheme design intelligent CAD is then put forward, which lays foundation for developing proto type system of welding positioner scheme design.
文摘With the accelerated development and utilization of urban underground space,the underground space design of complex based on rail transit has attracted much attention.By sorting out the integration concept and constructing the logical framework of integrated design,the integrated design strategy is proposed from the aspects of function,transportation,space and environment on the urban scale,and the evaluation points of integrated design effect are put forward from the aspects of accessibility,coordination,openness and symbolism.
基金Sponsored by Stage Achievements of Major Projects of Humanities and Social Sciences in Colleges and Universities of Anhui Province (SK2021ZD0036)。
文摘The memorial hall is an important place to learn red culture in China,which plays a positive role in carrying forward red culture and continuing revolutionary spirit.The outline of the “14^(th) Five-year” plan points out that “it should adhere to the integrated development,shape tourism with culture,highlight culture with tourism,and improve the system of integrated development of culture and tourism”.On this basis,it is proposed that the development of memorial halls in the new era needs the integration of culture and tourism.In this paper,the protection status of red culture of Hehan Detachment is investigated,and its existing problems are analyzed.The construction of Hehan Detachment Memorial Hall is taken as research object.The design strategy of the memorial hall is put forward,and rural red culture undertakings and the integrated development of culture and tourism industry are further established and improved.The research could provide a valuable reference for continuing red culture undertakings and innovating the development of culture and tourism industry at present.
文摘Based on the functions and characteristics of the interchange collector-distributor lanes,with Harbin as an example,it is proposed in this paper that the local characteristics and traffic flow characteristics should be considered in the design of the interchange collector-distributor lanes,which includes the analysis of function,location,and many other aspects,in hopes to provide reference for the design of collector-distributor lanes in other regions of our country.
基金supported by the National Key Research and Development Program of China (No.2022YFC2905204)the National Natural Science Foundation of China (Nos.52061028,52061039)the Interdisciplinary Innovation Fund of Nanchang University (IIFNCU),China (No.9166-27060003-ZD05).
文摘The interfacial structure plays an important role in the mechanical properties of magnesium matrix composite(MMCs)reinforced with graphene nanosheet(GNS)due to their poor wettability with the Mg matrix.An interface design strategy was proposed to form the semi-coherent interfacial structure with superior bonding strength.The lattice mismatch and interfacial bonding strength between Mg/rare earth oxide/carbon were utilized as key characteristics to evaluate the interfacial structure.Lanthanum oxide(La2O3)was selected as the intermediate candidate due to its low lattice mismatch and high interfacial bonding strength.To identify the interfacial structure of Mg/La2O3/graphene,first-principles calculations were conducted to calculate the ideal work of separation and electronic structure of the interfaces.Results demonstrated the presence of strong ionic and covalent interactions at the interface,which theoretically verified the strong interfacial bonding strength among Mg/La2O3/graphene interfaces.To experimentally validate the interface strength,MMCs with the interface structure of Mg/La2O3/GNS were developed.The formation of in-situ La2O3 led to the successful attainment of semi-coherent structures between Mg/La2O3 and La2O3/GNS,resulting in high strength and good ductility of the composite.Overall,this work proposes a new approach to interface design in MMCs with an enhancement of mechanical properties.
基金supported by the Major Science and Technology Projects of Inner Mongolia(Grant No.2021ZD0030)the National Natural Science Foundation of China(Grant No.52106278)+2 种基金the National Science Fund for Distinguished Young Scholars(Grant No.51925604)the Science and Technology Foundation of Guizhou Province(No.[2019]1422)Xplorer Prize。
文摘As a kind of large-scale physical energy storage,compressed air energy storage(CAES)plays an important role in the construction of more efficient energy system based on renewable energy in the future.Compared with traditional industrial compressors,the compressor of CAES has higher off-design performance requirements.From the perspective of design,it needs to pay attention not only to the performance of the design point,but also to the performance of all the stable working range.However,from the previous literature,no diagonal compressor was used in CAES which can meet the requirements,which also reflects the design program can be further improved.Therefore,this paper studies the design strategy of high efficient diagonal compressor for large-scale CAES,and gives the complete strategy algorithms used for different program modules.The pressure ratio,isentropic efficiency and stable working range are comprehensively considered.In the design process,the criteria for the key parameters of the diagonal flow angle of the diagonal compressor are given for the first time.The results show that the isentropic efficiency at the design point is 92.7%,the total pressure ratio is1.97,and the stable working range exceeds 20%,which meets the design requirements of the compressor for CAES and exceeds the overall performance of the previous compressors in the entire working range.
基金This work was supported by the National Natural Science Foundation of China(21672131,21775096)One Hundred People Plan of Shanxi Province,Shanxi Province“1331 Project”Key Innovation Team Construction Plan Cultivation Team(2018-CT-1)+7 种基金2018 Xiangyuan County Solid Waste Comprehensive Utilization Science and Technology Project(2018XYSDJS-05)Shanxi Province Foundation for Returness(2017-026)Shanxi Collaborative Innovation Center of High Value-added Utilization of Coal-related Wastes(2015-10-B3)the Shanxi Province Foundation for Selected(No.2019)the Innovative Talents of Higher Education Institutions of Shanxi,Scientific and Technological Innovation Programs of Higher Education Institutions in Shanxi(2019L0031)the Key R&D Program of Shanxi Province(201903D421069)the Shanxi Province Science Foundation(201901D111015)China Institute for Radiation Production and Scientific Instrument Center of Shanxi University(201512).
文摘Multicolor fluorescent probes based on small organic molecules have the advantages of low cost, good biocompatibility, easily modifiable molecular structures and adjustable fluorescence performance. In addition, small molecule multicolor fluorescent probes generally undergo multi-site or multi-step reactions, which means that they can be used for the specific detection of structurally similar substances in complex bio-systems. In this review, we focus on the design and application of multicolor fluorescent probes based on small organic molecules: single fluorophores with multiple reaction sites, multiple fluorophores with single reaction sites, or multiple fluorophores with multiple reaction sites. Moreover, a design strategy for multicolor fluorescent probes and its application in biological imaging are also summarized, providing a systematic plan for future research on fluorescent probes functionalized by small organic molecules. It will also play an important role in the development of additional functions for small organic molecule fluorescent probes.
基金supported by the National Key Basic Research Program of China(Grant No.2014CB921001)the Strategic Priority Research Program(B)of the Chinese Academy of Sciences(Grant No.XDB07030200)+2 种基金the Key Research Program of Frontier Sciences of the Chinese Academy of Sciences(Grant No.QYZDJ-SSW-SLH020)the National Key Research and Development Program of China(Grant No.2017YFA0303604)the National Natural Science Foundation of China(Grant Nos.11721404,and11674385)
文摘Since LiOsO_3 was discovered, obtaining easy-accessible polar metals for research and applications has been challenging. In this paper, we present a multilayer design strategy, which is configured as ferroelectric layer/carrier reservoir layer/isolation layer/substrate, for obtaining polar metals by electrostatically doping a strained ferroelectric material in a more effective way. In the proposed configuration, both 1 unit-cell thick BaTiO_3 and PbTiO_3 exhibited considerable Ti off-centering with various strains,which should extend the applicability of ferroelectric-based polar metals in ultra-thin devices. Moreover, engineered by the compressive strain and the BaTiO_3 thickness, the design strategy effectively achieved polar metallicity and dimensionalitytunable electronic states associated with the modulation of highly anisotropic properties such as electrical and electronic thermal conductivity, which may be helpful for designing ultra-thin, ultrafast, and low-power switch devices.
基金supported by the National Natural Science Foundation of China(nos.22005210,21833005,and 21833006).
文摘Singlet fission(SF)has attracted much attention on account of its great potential for applications in high efficiency solar energy conversion.The major roadblock to realize this potential is rooted in the limited availability of practical SF material with strong absorption,suitable triplet energy level,an efficient SF process,and good chemical stability.Quinoidal structures feature an innate diradical character,which endows these skeletons with SF potential yet results in some structural instability.
基金supported by the National Natural Science Foundation of China(Grant No.82202672)the Key Research and Development Program of Anhui Province(No.2022e07020017)+5 种基金China Postdoctoral Science Foundation Grant(2022M723049)the National Postdoctoral Program for Innovative Talents(BX20230350)Research Funds of Centre for Leading Medicine and Advanced Technologies of IHM(No.2023IHM02007)the Foundation of National Center for Translational Medicine(Shanghai)SHU Branch(No.SUITM-202301)Anhui Provincial Research Preparation Plan(2022AH040074),Natural science fund for colleges and universities in Anhui Proxince(2023AH053289)Research Fund of Anhui Institute of translational medicine(2022zhyx-C32).
文摘Magnesium-based biomaterials(MBMs)are one of the most promising materials for tissue engineering due to their unique mechanical properties and excellent functional properties.This review describes the development,advantages,and challenges of MBMs for biomedical applications,especially for tissue repair and regeneration.The history of the use of MBMs from the beginning of the 20th century is traced,and the transformative advances in contemporary applications of MBMs in areas such as orthopedics and cardiovascular surgery are emphasized.The review also provides insight into the signaling pathways affected by MBMs,such as the PI3K/Akt and RANKL/RANK/OPG pathways,which are critical for osteogenesis and angiogenesis.The review advocates that future research should focus on optimizing alloy compositions,surface modification and exploring innovative technologies such as 3D printing to improve the efficacy of MBMs in complex tissue repair.The potential of MBMs to tissue engineering and regenerative medicine is significant,urging further exploration and interdisciplinary collaboration to maximize their therapeutic effects.
基金financially supported by the National Natural Science Foundation of China(51972064 and 52222315)
文摘Rechargeable lithium-sulfur(Li-S)batteries,featuring high energy density,low cost,and environmental friendliness,have been dubbed as one of the most promising candidates to replace current commercial rechargeable Li-ion batteries.However,their practical deployment has long been plagued by the infamous“shuttle effect”of soluble Li polysulfides(LiPSs)and the rampant growth of Li dendrites.Therefore,it is important to specifically elucidate the solvation structure in the Li-S system and systematically summarize the feasibility strategies that can simultaneously suppress the shuttle effect and the growth of Li dendrites for practical applications.This review attempts to achieve this goal.In this review,we first introduce the importance of developing Li-S batteries and highlight the key challenges.Then,we revisit the working principles of Li-S batteries and underscore the fundamental understanding of LiPSs.Next,we summarize some representative characterization techniques and theoretical calculations applied to characterize the solvation structure of LiPSs.Afterward,we overview feasible designing strategies that can simultaneously suppress the shuttle effect of soluble LiPSs and the growth of Li dendrites.Finally,we conclude and propose personal insights and perspectives on the future development of Li-S batteries.We envisage that this timely review can provide some inspiration to build better Li-S batteries for promoting practical applications.
基金the Architectural Design and Research Institute of Tsinghua University that supported
文摘To enable further advanced study of Antarctica, a new station called Kunlun Station has been built by China in the Dome A region of the inland East Antarctic ice sheet. This paper describes the Antarctic station building design system that was developed with consideration of factors that may affect Kunlun Station, such as environment and climate, construction work and transport, environmental protection and energy conservation, psychological requirements and functional requirements. The design system included site selection, station planning, external building form, construction work, function and indoor environment, energy conservation, environmental protection, and material strategy. We also describe the experience acquired during the transportation and construction phases of Kunlun Station.
文摘Transformation and innovation of assistance model promote the transition of urban social assistance building to multi-functional building. This paper, on the basis of analyzing complexity and peculiarity of urban social assistance building, as well as researches and practices of sustainable improvement of domestic architecture, proposed environmental, social and economic objectives of the sustainable improvement of urban social assistance building, and elaborated design strategies from the perspectives of site selection and its impact on environment, application, evaluation and utilization of ecological technologies, reform of old buildings, flexible internal layout of building and combination of routine use and disaster use design, so as to improve social benefits and social assessment of assistance buildings sustainably, and to balance humanistic concerns and social resource input.
基金the Humanities and Social Sciences Foundation for Young Scholars of the Ministry of Education of China in 2018 (18YJC ZH197)。
文摘Based on the characteristics of regional culture,the application strategies of regional cultural elements in the design of cultural and creative products were analyzed.The aim is to effectively combine cultural and creative design with regional cultural elements to provide contemporary life with regional cultural and creative products,better serve modern needs,and enhance public awareness in the form of aesthetics.Firstly,the research status of regional culture and cultural and creative product design was summarized,and then the relationship between regional culture and product design was discussed from the aspects of appearance,material and craftsmanship.Afterwards,the value of regional cultural and creative product design was proposed,and the general strategies of regional cultural and creative products were further sorted out to make people feel the pleasure brought by the deep and strong regional culture.
文摘Road traffic conditions can have an important impact on the economic development of various regions.Under the background of rapid social and economic development,more and more expressway construction projects are initiated in various regions,including both new expressways and expansion of old expressways,and interchange design plays an important role.Scientific and reasonable interchange design can not only realize energy saving and low carbon footprint,but also be people-oriented and promote regional economic development.Therefore,this paper mainly analyzes the highway route and its interchange design strategy for reference.
基金Supported by National Natural Science Foundation of China(Grant Nos.51205347,51322506)Zhejiang Provincial Natural Science Foundation of China(Grant No.LR14E050003)+3 种基金Project of National Science and Technology Plan of China(Grant No.2013IM030500)Fundamental Research Funds for the Central Universities of ChinaInnovation Foundation of the State Key Laboratory of Fluid Power Transmission and Control of ChinaZhejiang University K.P.Chao’s High Technology Development Foundation of China
文摘Traditional modular design methods lead to product maintenance problems, because the module form of a system is created according to either the function requirements or the manufacturing considerations. For solving these problems, a new modular design method is proposed with the considerations of not only the traditional function related attributes, but also the maintenance related ones. First, modularity parameters and modularity scenarios for product modularity are defined. Then the reliability and economic assessment models of product modularity strategies are formulated with the introduction of the effective working age of modules. A mathematical model used to evaluate the difference among the modules of the product so that the optimal module of the product can be established. After that, a multi-objective optimization problem based on metrics for preventive maintenance interval different degrees and preventive maintenance economics is formulated for modular optimization. Multi-objective GA is utilized to rapidly approximate the Pareto set of optimal modularity strategy trade-offs between preventive maintenance cost and preventive maintenance interval difference degree. Finally, a coordinate CNC boring machine is adopted to depict the process of product modularity. In addition, two factorial design experiments based on the modularity parameters are constructed and analyzed. These experiments investigate the impacts of these parameters on the optimal modularity strategies and the structure of module. The research proposes a new modular design method, which may help to improve the maintainability of product in modular design.
基金Supported by National Science and Technology Council(CONACYT)of Mexico(Grant No.CB-2010-01-154430)PROMEP Program of the Public Education Secretariat(SEP)of MexicoFund for Research Support(FAI)of UASLP
文摘Although several research works in the literature have focused on studying the capabilities of additive manufacturing(AM) systems, few works have addressed the development of Design for Additive Manufacturing(DfAM) knowledge,tools, rules, and methodologies, which has limited the penetration and impact of AM in industry. In this paper a comprehensive review of design and manufacturing strategies for Fused Deposition Modelling(FDM) is presented.Consequently, several DfAM strategies are proposed and analysed based on existing research works and the operation principles, materials, capabilities and limitations of the FDM process. These strategies have been divided into four main groups: geometry, quality, materials and sustainability. The implementation and practicality of the proposed DfAM is illustrated by three case studies. The new proposed DfAM strategies are intended to assist designers and manufacturers when making decisions to satisfy functional needs, while ensuring manufacturability in FDM systems.Moreover, many of these strategies can be applied or extended to other AM processes besides FDM.