The representation and acquisition of a product gene is a crucial problem in product evolutionary design. A new methodology of product gene representation and acquisition from a population of product cases is proposed...The representation and acquisition of a product gene is a crucial problem in product evolutionary design. A new methodology of product gene representation and acquisition from a population of product cases is proposed, and the methodology for product evolutionary design based on a population of product cases is realized. By properly classifying product cases according to its product species, the populations of product cases are divided and a model is established. Knowledge of the scheme design is extracted and formulated as the function base, principle base, and structure base, which are then combined to form a product gene. Subsequently, the product gene tree is created and represented by object-oriented method. Then combining this method with the evolutionary reasoning technology, an intelligent and automatic evolutionary scheme design of product based on the population of product cases is realized. This design method will be helpful in the processing of knowledge formulation, accumulation, and reuse, and in addressing the difficulty of acquiring design knowledge in traditional design. In addition, the disadvantages of manual case adaptation and update in case-based reasoning can be eliminated. Moreover, by optimizing the design scheme in multiple levels and aspects of product function, principle, and structure etc., the level of creativity in the scheme design can be improved.展开更多
Genome-wide association study (GWAS) has become a widely accepted strategy for decoding genotype- phenotype associations in many species thanks to advances in next-generation sequencing (NGS) technol- ogies. Maize...Genome-wide association study (GWAS) has become a widely accepted strategy for decoding genotype- phenotype associations in many species thanks to advances in next-generation sequencing (NGS) technol- ogies. Maize is an ideal crop for GWAS and significant progress has been made in the last decade. This review summarizes current GWAS efforts in maize functional genomics research and discusses future prospects in the omics era. The general goal of GWAS is to link genotypic variations to corresponding dif- ferences in phenotype using the most appropriate statistical model in a given population. The current re- view also presents perspectives for optimizing GWAS design and analysis. GWAS analysis of data from RNA, protein, and metabolite-based omics studies is discussed, along with new models and new popula- tion designs that will identify causes of phenotypic variation that have been hidden to date. The joint and continuous efforts of the whole community will enhance our understanding of maize quantitative traits and boost crop molecular breeding designs.展开更多
文摘The representation and acquisition of a product gene is a crucial problem in product evolutionary design. A new methodology of product gene representation and acquisition from a population of product cases is proposed, and the methodology for product evolutionary design based on a population of product cases is realized. By properly classifying product cases according to its product species, the populations of product cases are divided and a model is established. Knowledge of the scheme design is extracted and formulated as the function base, principle base, and structure base, which are then combined to form a product gene. Subsequently, the product gene tree is created and represented by object-oriented method. Then combining this method with the evolutionary reasoning technology, an intelligent and automatic evolutionary scheme design of product based on the population of product cases is realized. This design method will be helpful in the processing of knowledge formulation, accumulation, and reuse, and in addressing the difficulty of acquiring design knowledge in traditional design. In addition, the disadvantages of manual case adaptation and update in case-based reasoning can be eliminated. Moreover, by optimizing the design scheme in multiple levels and aspects of product function, principle, and structure etc., the level of creativity in the scheme design can be improved.
文摘Genome-wide association study (GWAS) has become a widely accepted strategy for decoding genotype- phenotype associations in many species thanks to advances in next-generation sequencing (NGS) technol- ogies. Maize is an ideal crop for GWAS and significant progress has been made in the last decade. This review summarizes current GWAS efforts in maize functional genomics research and discusses future prospects in the omics era. The general goal of GWAS is to link genotypic variations to corresponding dif- ferences in phenotype using the most appropriate statistical model in a given population. The current re- view also presents perspectives for optimizing GWAS design and analysis. GWAS analysis of data from RNA, protein, and metabolite-based omics studies is discussed, along with new models and new popula- tion designs that will identify causes of phenotypic variation that have been hidden to date. The joint and continuous efforts of the whole community will enhance our understanding of maize quantitative traits and boost crop molecular breeding designs.