Optimization of Extraction Process of Clerodendrum philippinum Schauer var. simplex Mlodenke Total Flavonoids(CPTF) by Central Composite Design-Response Surface Methodology

[Objectives] The research aimed to optimize extraction process of Clerodendrum philippinum Schauer var. simplex Mlodenke total flavonoids( CPTF),and provide reference for its development and utilization. [Methods] Based on single-factor test,ethanol concentration,extraction temperature and extraction time were taken as independent variables,and total flavonoids yield was taken as dependent variable. The test was conducted according to central composite design principle. Multivariate linear regression and binomial equation fitting of the result were conducted,and extraction process of CPTF was optimized by using response surface methodology. [Results]The optimal extraction process of CPTF was as below: ethanol concentration 54. 76%,extraction temperature 83. 92℃,extraction time 102. 64 min,solid-liquid ratio 1:20,extraction for twice. [Conclusions] The extraction process of CPTF by central composite design-response surface methodology was simple and feasible,with reliable prediction result,which was suitable for industrial production.

Optimization of Extraction Process of Total Flavonoids from Akebia trifoliata (Thunb.) Koidz. by Central Composite Design-Response Surface Methodology

[Objectives]To optimize extraction process of total flavonoids from Akebia trifoliata( Thunb.) Koidz.,so as to provide references for development and use of Akebia trifoliata( Thunb.) Koidz. [Methods]The extraction rate of total flavonoids of Akebia trifoliata( Thunb.)Koidz. was taken as observation indicator. On the basis of single factor experiment,central composite design( CCD) was used to evaluate the effects of the extraction temperature,extraction time,and ethanol concentration on the extraction process. Multiple linear regression and binomial fitting were used,and response surface methodology( RSM) was used to select the optimum extraction process. [Results] The optimum extraction process conditions for total flavonoids of Akebia trifoliata( Thunb.) Koidz. was extraction temperature: 83. 92 ℃; extraction time:96. 47 min; ethanol concentration: 63. 92%; extraction times: two times; solid to liquid ratio: 1 ∶ 20; extraction rate of total flavonoids:4. 55%. [Conclusions] The central composite design-response surface methodology( CCD-RSM) is simple,convenient,and feasible for extraction of total flavonoids from Akebia trifoliata( Thunb.) Koidz.,and the prediction results are reliable.

Generalized nth-Order Perturbation Method Based on Loop Subdivision Surface Boundary Element Method for Three-Dimensional Broadband Structural Acoustic Uncertainty Analysis

In this paper,a generalized nth-order perturbation method based on the isogeometric boundary element method is proposed for the uncertainty analysis of broadband structural acoustic scattering problems.The Burton-Miller method is employed to solve the problem of non-unique solutions that may be encountered in the external acoustic field,and the nth-order discretization formulation of the boundary integral equation is derived.In addition,the computation of loop subdivision surfaces and the subdivision rules are introduced.In order to confirm the effectiveness of the algorithm,the computed results are contrasted and analyzed with the results under Monte Carlo simulations(MCs)through several numerical examples.

Monte Carlo method for evaluation of surface emission rate measurement uncertainty

The aim of this study is to evaluate the uncertainty of 2πα and 2πβ surface emission rates using the windowless multiwire proportional counter method.This study used the Monte Carlo method (MCM) to validate the conventional Guide to the Expression of Uncertainty in Measurement (GUM) method.A dead time measurement model for the two-source method was established based on the characteristics of a single-channel measurement system,and the voltage threshold correction factor measurement function was indirectly obtained by fitting the threshold correction curve.The uncertainty in the surface emission rate was calculated using the GUM method and the law of propagation of uncertainty.The MCM provided clear definitions for each input quantity and its uncertainty distribution,and the simulation training was realized with a complete and complex mathematical model.The results of the surface emission rate uncertainty evaluation for four radioactive plane sources using both methods showed the uncertainty’s consistency E_(n)<0.070 for the comparison of each source,and the uncertainty results of the GUM were all lower than those of the MCM.However,the MCM has a more objective evaluation process and can serve as a validation tool for GUM results.

Approach Based on Response-Surface Method to Optimize Lining of Dies Used in 3D Free-Bending Forming Technology

In three-dimensional free-bending forming(3D-FBF),the tube is not overly constrained,and the plastic deformation behavior and forming quality of the bent tube are significantly affected by the critical structure of the forming die lining.However,the effects of die-lining structural parameters on the tube quality,and a method to determine the combination of die-lining structural parameters is yet to be devised.This study aims to propose a new framework that allows one to understand the effects of various die-lining structural parameters on tube quality and to propose the best combination of die-lining structural parameters.First,finite-element modeling is performed to simulate 3D-FBF and examine the effects of individual die-lining structures on the quality of tube formation.The simulation results show that the deformation-zone length and die gap are positively correlated with the tube-section distortion and wall-thickness variation,whereas it shows an opposite trend with respect to the bending radius.Additionally,the lining chamfer radius of the bending die and the guide lining chamfer radius minimally affect the tube forming quality.Subsequently,the optimal die-lining structure is obtained using the response-surface method.The tube cross-sectional distortion rate reduced from 2.73 to 2.53%after the die lining is optimized.Additionally,the average inner-wall thickness reduced to 1.06 mm,whereas the average outer-wall thickness increased to 0.97 mm.This paper proposes a method for optimizing the forming-die-lining mechanism and for improving the tube forming quality in 3D-FBF.

Optimizing Bucket Elevator Performance through a Blend of Discrete Element Method, Response Surface Methodology, and Firefly Algorithm Approaches

This research introduces a novel approach to enhancing bucket elevator design and operation through the integration of discrete element method(DEM)simulation,design of experiments(DOE),and metaheuristic optimization algorithms.Specifically,the study employs the firefly algorithm(FA),a metaheuristic optimization technique,to optimize bucket elevator parameters for maximizing transport mass and mass flow rate discharge of granular materials under specified working conditions.The experimental methodology involves several key steps:screening experiments to identify significant factors affecting bucket elevator operation,central composite design(CCD)experiments to further explore these factors,and response surface methodology(RSM)to create predictive models for transport mass and mass flow rate discharge.The FA algorithm is then applied to optimize these models,and the results are validated through simulation and empirical experiments.The study validates the optimized parameters through simulation and empirical experiments,comparing results with DEM simulation.The outcomes demonstrate the effectiveness of the FA algorithm in identifying optimal bucket parameters,showcasing less than 10%and 15%deviation for transport mass and mass flow rate discharge,respectively,between predicted and actual values.Overall,this research provides insights into the critical factors influencing bucket elevator operation and offers a systematic methodology for optimizing bucket parameters,contributing to more efficient material handling in various industrial applications.

INTEGRATION SHAPE AND SIZING OPTIMIZATION OF COMPOSITE WING STRUCTURE BASED ON RESPONSE SURFACE METHOD

An effective optimization method for the shape/sizing design of composite wing structures is presented with satisfying weight-cutting results. After decoupling, a kind of two-layer cycled optimization strategy suitable for these integrated shape/sizing optimization is obtained. The uniform design method is used to provide sample points, and approximation models for shape design variables. And the results of sizing optimization are construct- ed with the quadratic response surface method （QRSM）. The complex method based on QRSM is used to opti- mize the shape design variables and the criteria method is adopted to optimize the sizing design variables. Compared with the conventional method, the proposed algorithm is more effective and feasible for solving complex composite optimization problems and has good efficiency in weight cutting.

Surface edge element method for 3-D electromagnetic computation

A surface edge element method is proposed and implemented in the study ofelectromagnetic scattering fields of general targets. The basis functions for surfaces of arbitraryshape are derived according to the geometrical properties of each triangular patch. The proposedbasis functions are 3-D linear functions and the tangential components of the vectors are continuousas the traditional edge element method. Combined field integral equations (CFIE) that include bothelectrical field and magnetic field integral equations are used to model the electromagneticscattering of general dielectric targets. Special treatment for singularity is presented to enhancethe quality of numerical solutions. The proposed method is used to compute the scattering fieldsfrom various targets. Numerical results obtained by the proposed method are validated by resultsfrom other numerical methods.

A METHOD FOR PREDICTING BUCKLING LOADS OF COMPOSITE LAMINATED STRIPS WITH A SURFACE NOTCH

Surface notches lower the stiffness of laminated strips, so they lower the buckling loads of the laminated strips, too. In this paper a new method is proposed to predict the buckling loads of the laminated strips with a surface notch. The theoretical and experimental results show that the buckling loads decrease as the depth or width of the surface notches increase; when the stacking sequence of the laminated strips is [0°/0°/+ θ/-θ/0°/0°/+θ/-θ] s , the buckling load decrease as θ increases. It proves that the method is reliable and significant.

Finite Element Analysis for Magneto-Convection Heat Transfer Performance in Vertical Wavy Surface Enclosure:Fin Size Impact

The goal of this paper is to represent a numerical study of magnetohydrodynamic mixed convection heat transfer in a lid-driven vertical wavy enclosure with a fin attached to the bottomwall.We use a finite elementmethod based on Galerkin weighted residual(GWR)techniques to set up the appropriate governing equations for the present flow model.We have conducted a parametric investigation to examine the impact of Hartmann and Richardson numbers on the flow pattern and heat transmission features inside a wavy cavity.We graphically represent the numerical results,such as isotherms,streamlines,velocity profiles,local and mean Nusselt numbers,and average surface temperature.Comparisons between the results of this work and previously published work in a literature review have been produced to examine the reliability and consistency of the data.The different sizes of the fin surface significantly impact flow creation and temperature fields.Additionally,the long fin size is necessary to enhance the heat transfer rate on the right surface at large Richardson numbers and low Hartmann numbers.Fin surfaces can significantly increase the mixing of fluid inside the enclosure,which can mean reductions in reaction times and operating costs,along with increases in heat transfer and efficiency.

Impact of surface-reflected seismic waves on the seismic isolation performance of circular tunnel isolation layers

Seismic isolation is an effective strategy to mitigate the risk of seismic damage in tunnels.However,the impact of surface-reflected seismic waves on the effectiveness of tunnel isolation layers remains under explored.In this study,we employ the wave function expansion method to provide analytical solutions for the dynamic responses of linings in an elastic half-space and an infinite elastic space.By comparing the results of the two models,we investigate the seismic isolation effect of tunnel isolation layers induced by reflected seismic waves.Our findings reveal significant differences in the dynamic responses of the lining in the elastic half-space and the infinitely elastic space.Specifically,the dynamic stress concentration factor(DSCF)of the lining in the elastic half-space exhibits periodic fluctuations,influenced by the incident wave frequency and tunnel depth,while the DSCF in the infinitely elastic space remain stable.Overall,the seismic isolation application of the tunnel isolation layer is found to be less affected by surface-reflected seismic waves.Our results provide valuable insights for the design and assessment of the seismic isolation effect of tunnel isolation layers.

Running-in Test and Fractal Methodology for Worn Surface Topography Characterization

Studying and understanding of the surface topography variation are the basis for analyzing tribological problems,and characterization of worn surface is necessary.Fractal geometry offers a more accurate description for surface roughness that topographic surfaces are statistically self-similar and can be quantitatively evaluated by fractal parameters.The change regularity of worn surface topography is one of the most important aspects of running-in study.However,the existing research normally adopts only one friction matching pair to explore the surface topography change,which interrupts the running-in wear process and makes the experimental result lack authenticity and objectivity.In this paper,to investigate the change regularity of surface topography during the real running-in process,a series of running-in tests by changing friction pairs under the same operating conditions are conducted on UMT-II Universal Multifunction Tester.The surface profile data are acquired by MiaoXAM2.5X-50X Ultrahigh Precision Surface 3D Profiler and analyzed using fractal dimension D,scale coefficient C and characteristic roughness Ra ＊based on root mean square（RMS） method.The characterization effects of the three parameters are discussed and compared.The results obtained show that there exists remarkable fractal feature of surface topography during running-in process,both D and Ra ＊increase gradually,while C decreases slowly as the wear-in process goes on,and all parameters tend to be stable when the wear process steps into the normal wear process.Ra ＊illustrates higher sensitivity for rough surface characterization compared with the other two parameters.In addition,the running-in test carried with a set of identical surface properties is more scientific and reasonable than the traditional one.The proposed research further indicates that the fractal method can quantitatively measure the rough surface,which also provides an evidence for running-in process identification and tribology design.

Long-term deformation analysis of Shuibuya concrete face rockfill dam based on response surface method and improved genetic algorithm

Due to the size effects of rockfill materials, the settlement difference between numerical simulation and in situ monitoring of rockfill dams is a topic of general concern.The constitutive model parameters obtained from laboratory triaxial tests often underestimate the deformation of high rockfill dams.Therefore, constitutive model parameters obtained by back analysis were used to calculate and predict the long-term deformation of rockfill dams.Instead of using artificial neural networks (ANNs), the response surface method (RSM) was employed to replace the finite element simulation used in the optimization iteration.Only 27 training samples were required for RSM, improving computational efficiency compared with ANN, which required 300 training samples.RSM can be used to describe the relationship between the constitutive model parameters and dam settlements.The inversion results of the Shuibuya concrete face rockfill dam (CFRD) show that the calculated settlements agree with the measured data, indicating the accuracy and efficiency of RSM.

Statistical Modification Analysis of Helical Planetary Gears based on Response Surface Method and Monte Carlo Simulation

Tooth modification technique is widely used in gear industry to improve the meshing performance of gearings. However, few of the present studies on tooth modification considers the influence of inevitable random errors on gear modification effects. In order to investigate the uncertainties of tooth modification amount variations on system＇s dynamic behaviors of a helical planetary gears, an analytical dynamic model including tooth modification parameters is proposed to carry out a deterministic analysis on the dynamics of a helical planetary gear. The dynamic meshing forces as well as the dynamic transmission errors of the sun-planet 1 gear pair with and without tooth modifications are computed and compared to show the effectiveness of tooth modifications on gear dynamics enhancement. By using response surface method, a fitted regression model for the dynamic transmission error（DTE） fluctuations is established to quantify the relationship between modification amounts and DTE fluctuations. By shifting the inevitable random errors arousing from manufacturing and installing process to tooth modification amount variations, a statistical tooth modification model is developed and a methodology combining Monte Carlo simulation and response surface method is presented for uncertainty analysis of tooth modifications. The uncertainly analysis reveals that the system＇s dynamic behaviors do not obey the normal distribution rule even though the design variables are normally distributed. In addition, a deterministic modification amount will not definitely achieve an optimal result for both static and dynamic transmission error fluctuation reduction simultaneously.

Low/distortion on Exterior Surface of Auto Body and Its Correction Method

Surface low/distortion is one of the most challenging surface deflections that have a great effect on the exterior appearance of automobiles.Most studies on surface distortion/deflection have focused on evaluation and visualization techniques,the research work on correction or prevention of surface low/distortion is limited,and there is no perfect surface low/distortion corrective method that can satisfy the needs of the engineering.A B-spline based geometry morphing algorithm is proposed and then a new program based on UG-NX platform is developed to modify the die face in the surface low/distortion areas.To verify this developed system,the experimental dies that can replicate the surface low/distortion phenomenon successfully is put to use.Five geometric variables are introduced to describe the basic geometry of typical depression features of automotive outer panels.The experimental dies are then designed to reflect various combinations of these geometric parameters.The stamping experiments are conducted on cold rolled grade 5（CR5） sheet steel and various static measurements,such as oil-stoning,laser scanner,etc,are performed to measure and record the surface low/distortions.Three approaches including good bearing,holds in blank and die face morphing that aim to correct low/distortions are tried out and surface low/distortions are observed in the specimen with reverse draw depth of 10 mm.The measurement results show that die morphing is a practical and effective method to correct the surface low/distortion.The correction method proposed can be used to minimize the occurrence of surface low/distortion in die manufacturing,which has certain reference significance to the correction of surface low/distortion.

Hybrid method for investigation of electromagnetic scattering from conducting target above the randomly rough surface

A current based hybrid method （HM） is proposed which combines the method of moment （MOM） with the Kirchhoff approximation （KA） for the analysis of scattering interaction between a two-dimensional （2D） infinitely long conducting target with arbitrary cross section and a one-dimensional （1D） Gaussian rough surface. The electromagnetic scattering region in the HM is split into KA region and MOM region. The electric field integral equation （EFIE） in MOM region （target） is derived, the computational time of the HM depends mainly on the number of unknowns of the target. The bistatic scattering coefficient for the infinitely long cylinder above the rough surface with Gaussian roughness spectrum is calculated, and the numerical results are compared and verified with those obtained by the conventional MOM, which shows the high efficiency of the HM. Finally, the influence of the size, location of the target, the rms height and correlation length of the rough surface on the bistatic scattering coefficient with different polarizations is discussed in detail.

Distributed Collaborative Response Surface Method for Mechanical Dynamic Assembly Reliability Design

Because of the randomness of many impact factors influencing the dynamic assembly relationship of complex machinery, the reliability analysis of dynamic assembly relationship needs to be accomplished considering the randomness from a probabilistic perspective. To improve the accuracy and efficiency of dynamic assembly relationship reliability analysis, the mechanical dynamic assembly reliability（MDAR） theory and a distributed collaborative response surface method（DCRSM） are proposed. The mathematic model of DCRSM is established based on the quadratic response surface function, and verified by the assembly relationship reliability analysis of aeroengine high pressure turbine（HPT） blade-tip radial running clearance（BTRRC）. Through the comparison of the DCRSM, traditional response surface method（RSM） and Monte Carlo Method（MCM）, the results show that the DCRSM is not able to accomplish the computational task which is impossible for the other methods when the number of simulation is more than 100 000 times, but also the computational precision for the DCRSM is basically consistent with the MCM and improved by 0.40-4.63% to the RSM, furthermore, the computational efficiency of DCRSM is up to about 188 times of the MCM and 55 times of the RSM under 10000 times simulations. The DCRSM is demonstrated to be a feasible and effective approach for markedly improving the computational efficiency and accuracy of MDAR analysis. Thus, the proposed research provides the promising theory and method for the MDAR design and optimization, and opens a novel research direction of probabilistic analysis for developing the high-performance and high-reliability of aeroengine.

Optimization of High-Protein Glutinous Rice Flour Production Using Response Surface Method

A response surface method was employed to study the effect of α-amylase concentration, hydrolysis temperature and time on the production of high protein glutinous rice flour(HPGRF). The suspension of glutinous rice flour(15%) that contained 6.52% protein was gelatinized and subsequently hydrolyzed by thermostable α-amylase. The hydrolysis yielded 0.144–0.222 g/g HPGRF with 29.4%–45.4% protein content. Hydrolysis time exerted a significant effect, while enzyme concentration and hydrolysis temperature showed insignificant effect on the protein content and production yield of HPGRF. The result of response surface method showed that the optimum condition for the production of HPGRF that contained at least 36% protein was treating gelatinized 15% glutinous rice flour suspension with 0.90 Kilo Novo α-amylase Unit(KNU)/g α-amylase at 80 oC for 99 min. By carrying out the predicted hydrolysis condition, HPGRF with 35.9% protein and 61.8% carbohydrates was resulted. The process yielded 0.172 g/g HPGRF. HPGRF contained higher amount of essential amino acids compared to glutinous rice flour. HPGRF had higher solubility and lower swelling power, and also showed no pasting peak compared with glutinous rice flour.

Redesigned Surface Based Machining Strategy and Method in Peripheral Milling of Thin-walled Parts

Currently, simultaneously ensuring the machining accuracy and efficiency of thin-walled structures especially high performance parts still remains a challenge. Existing compensating methods are mainly focusing on 3-aixs machining, which sometimes only take one given point as the compensative point at each given cutter location. This paper presents a redesigned surface based machining strategy for peripheral milling of thin-walled parts. Based on an improved cutting force/heat model and finite element method（FEM） simulation environment, a deflection error prediction model, which takes sequence of cutter contact lines as compensation targets, is established. And an iterative algorithm is presented to determine feasible cutter axis positions. The final redesigned surface is subsequently generated by skinning all discrete cutter axis vectors after compensating by using the proposed algorithm. The proposed machining strategy incorporates the thermo-mechanical coupled effect in deflection prediction, and is also validated with flank milling experiment by using five-axis machine tool. At the same time, the deformation error is detected by using three-coordinate measuring machine. Error prediction values and experimental results indicate that they have a good consistency and the proposed approach is able to significantly reduce the dimension error under the same machining conditions compared with conventional methods. The proposed machining strategy has potential in high-efficiency precision machining of thin-walled parts.

An Intelligent Method for Structural Reliability Analysis Based on Response Surface

As water depth increases, the structural safety and reliability of a system become more and more important and challenging. Therefore, the structural reliability method must be applied in ocean engineering design such as offshore platform design. If the performance function is known in structural reliability analysis, the first-order second-moment method is often used. If the performance function could not be definitely expressed, the response surface method is always used because it has a very clear train of thought and simple programming. However, the traditional response surface method fits the response surface of quadratic polynomials where the problem of accuracy could not be solved, because the true limit state surface can be fitted well only in the area near the checking point. In this paper, an intelligent computing method based on the whole response surface is proposed, which can be used for the situation where the performance function could not be definitely expressed in structural reliability analysis. In this method, a response surface of the fuzzy neural network for the whole area should be constructed first, and then the structural reliability can be calculated by the genetic algorithm. In the proposed method, all the sample points for the training network come from the whole area, so the true limit state surface in the whole area can be fitted. Through calculational examples and comparative analysis, it can be known that the proposed method is much better than the traditional response surface method of quadratic polynomials, because, the amount of calculation of finite element analysis is largely reduced, the accuracy of calculation is improved, and the true limit state surface can be fitted very well in the whole area. So, the method proposed in this paper is suitable for engineering application.