Research Progress of Atrial Fibrillation Detection Technology

Atrial fibrillation (AF) is the most common chronic arrhythmia in clinical practice, which can cause high disability and mortality with the progress of the disease. Many studies at home and abroad have shown that the incidence of atrial fibrillation gradually increases with age. Clinically, the onset of most AF patients is insidious, which is difficult to capture by routine electrocardiogram, and there is some difficulty in the diagnosis. In order to make the early diagnosis of atrial fibrillation more efficient and accurate, this paper reviews the current status and research progress of detection technology for atrial fibrillation at home and abroad, in order to provide a scientific basis for the early diagnosis of atrial fibrillation.

Analysis of Detection and Monitoring Technology in the Construction and Maintenance of Large Bridges

Currently,there is significant attention placed on the construction,management,and maintenance of large service bridges.Within the realm of bridge maintenance management,the utilization of detection and monitoring technology is indispensable.By employing these technologies,we can effectively identify any structural defects within the bridge,promptly uncover unknown risks,proactively establish maintenance strategies,and prevent the rapid deterioration of bridge conditions.This article aims to explore the advantages of applying bridge monitoring and testing technology and to discuss various methods for implementing detection and monitoring technology throughout the construction,management,and maintenance phases of large bridges.Ultimately,this will contribute to ensuring the safe operation of large bridges.

Applications of Ultrasonic Detection Technology in Bridge Concrete Pile Foundation Detection

In this paper,the application strategy of ultrasonic detection technology in the detection of concrete foundation piles is analyzed using a construction project as an example.It includes a basic overview of the project,an overview of ultrasonic testing technology in bridge concrete pile foundation testing,and an analysis of its practical application in the concrete pile foundation testing of this project.The objective of this analysis is to provide some reference for the application of ultrasonic testing technology and the improvement of the quality of bridge concrete pile foundation testing.

Discussion on Test and Detection Technology of Highway Asphalt Pavement

The road traffic industry in China has been developing rapidly in recent years.Asphalt has become the main material in road construction because of its seamless connection and short construction period,and it has an important impact on the overall quality of highway construction.Therefore,it is necessary to conduct scientific and reasonable tests and detections for highway asphalt pavement.This paper presents a discussion on the test and detection technology of highway asphalt pavement for future reference.

Review on the application of upconversion nanomaterials in heavy metal detection

As a widespread element,heavy metals have a significant impact on human health and threaten human health.It is of great significance to develop analytical technologies that can detect heavy metal ions quickly and accurately.In comparison to conventional fluorescent materials such as organic dyes,quantum dot(QD)labels,and carbon quantum dots(CD),fluorescence detection technology utilizing lanthanide(Ln)ion-doped upconversion nanoparticles(UCNPs)stands out due to its distinctive attributes.These include a notably reduced autofluorescence background,enhanced tissue penetration capabilities,biocompatibility with cellular tissues,and minimal photodamage inflicted on biological samples.The utilization of this technology has garnered considerable attention across multiple fields.In the domain of heavy metal detection,traditional laboratory methods necessitate costly instrumentation and a fully equipped laboratory,involving intricate sample processing procedures and protracted detection periods,as well as a demand for skilled personnel.In contrast,the implementation of this material offers rapid and cost-effective detection,significantly mitigating the technical barriers for operators.Consequently,this represents an exceptional avenue to curtail expenses and broaden the scope of detection within the analytical process.This paper reviews the research progress of UCNPs in the detection of heavy metal ions,encompassing a brief elucidation of the luminescence principle of upconversion nanomaterials and commonly used detection principles.Additionally,it provides a detailed overview of the research status of several common non-metal ions and essential heavy metals.Furthermore,it summarizes the current focal points in UCNP detection and discusses the challenges and prospects associated with it.

Analysis of Bridge Inspection Technology for Highway Reconstruction and Expansion

This article focuses on bridge testing technologies in highway construction and expansion projects.It provides an overview of the inspection process for bridges in highway reconstruction and expansion projects,the main inspections,and strategies for improving the quality of inspections.Relevant units should conduct bridge inspections using appearance inspections,special inspections,and bearing capacity assessments in highway reconstruction and expansion projects.To effectively improve testing quality,relevant units should also focus on establishing and improving testing standards,strengthening material testing,and improving the overall quality of the testing personnel.This research aims to enhance the quality of highway reconstruction and expansion projects by supporting the sensible application of bridge inspection technology.

Review of advanced road materials, structures, equipment, and detection technologies

As a vital and integral component of transportation infrastructure,pavement has a direct and tangible impact on socio-economic sustainability.In recent years,an influx of groundbreaking and state-of-the-art materials,structures,equipment,and detection technologies related to road engineering have continually and progressively emerged,reshaping the landscape of pavement systems.There is a pressing and growing need for a timely summarization of the current research status and a clear identification of future research directions in these advanced and evolving technologies.Therefore,Journal of Road Engineering has undertaken the significant initiative of introducing a comprehensive review paper with the overarching theme of“advanced road materials,structures,equipment,and detection technologies”.This extensive and insightful review meticulously gathers and synthesizes research findings from 39 distinguished scholars,all of whom are affiliated with 19 renowned universities or research institutions specializing in the diverse and multidimensional field of highway engineering.It covers the current state and anticipates future development directions in the four major and interconnected domains of road engineering:advanced road materials,advanced road structures and performance evaluation,advanced road construction equipment and technology,and advanced road detection and assessment technologies.

Editorial:special issue on medical detection technology

Medical detection technology-from biochemical analysis to medical imaging has witnessed tremendous progress in the past decades,driven by the breakthrough of biomedical and scientific theories,the innovation of engineering techniques,as well as the discovery of new contrast mechanisms.These substantial progresses have significantly promoted

Improved Nucleic Acid Spot Hybridization Technique for Detection of Potato Spindle Tuber Viroid(PSTVd)

Potato spindle tuber viroid(PSTVd)disease is one of the major diseases that threatens potato production.Therefore,an advanced,rapid and sensitive detection technology is needed to detect the disease for better control.In order to establish an easier nucleic acid spot hybridization(NASH)method,some studies were tried as the followings:(1)the pre-hybridization step of nucleic acid spot hybridization(NASH)was omitted compared with ordinary way;(2)RNA extraction(phenol extraction and Ames buffer extraction)methods were compared;(3)fixed RNA by UV lamp and oven compared with UV cross-linker;(4)hybridized the RNA in shaking incubator and so on.The results showed that RNA extracted by Ames buffer was more effective than by the phenol extraction method.Besides,the result of hybridization without pre-hybridization step was better than that with 1.5 h of pre-hybridization.The more important discovery was that the shaking incubator could replace the hybridization oven and the ordinary UV lamp could replace the UV cross-linker.After a long term repeated research and testing,a new hybridization system that could rapidly detect the PSTVd by improved NASH technique merely using common instruments and equipment was established.

Application of Technology in the Fault Diagnosis of Large Centrifugal Pump Units

In order to promote the stability of centrifugal pump units and maximize the role of centrifugal pumps, this paper analyzes the composition and basic working principle of centrifugal pumps, presents the main concerns of centrifugal pump maintenance, and finally investigates the common faults and maintenance methods of centrifugal pumps for reference.

Increased Prevalence of Thyroid Nodules Across Nearly 10 Years in Shanghai,China

Objective This study aimed to determine whether the prevalence of thyroid nodules(TNs)increased due to modern lifestyles or other factors,despite the advances in screening and diagnostic tools.Methods This study included 3474 pairs of participants,who were matched by gender and age(±3 years)from two cross-sectional sampling surveys:(1)the program on the iodine nutritional status and related health status of residents in Shanghai in 2009;(2)the thyroid disease screening program for adults in Shanghai between 2017 and 2018.The prevalence of TNs and thyroid diseases in 2009 and 2017–2018 were compared,and the potential risk factors of TNs were detected.Results The prevalence of TNs in 2009 was 28.9%:22.5%in males and 34.5%in females.In 2017,this increased to 43.8%:37.9%in males and 49.1%in females.The prevalence of TNs significantly increased from 2009 to 2017(odds ratio,1.486;95%confidence interval,1.238–1.786).In addition,female gender,thyroid disease history,and age were the main risk factors for TNs after adjusting for confounders in the logistic regression across the time period.Conclusion The prevalence of TNs significantly increased across nearly 10 years in Shanghai.

Technical Analysis of Highway Bridge Static Load Test

Highway bridges are an important part of the transportation industry and can promote social economic construction and development.In actual operation,highway bridges are often damaged due to overload and natural factors,which tend to affect the safety and shorten the service life of these bridges.Assessing the overall state and performance of highway bridges is therefore a key element.Static load test,which is a type of sustainable detection experiment,has many advantages,including low cost,high efficiency,and high accuracy.In this paper,the bridge structure is analyzed through the application of theoretical calculations and relevant comparisons,so as to judge the operating state of the bridge.

An early screening model of pulse detection technology for hepatic steatosis

Background The increasing prevalence of hepatic steatosis presents a considerable challenge to public health.There is a critical need for the development of novel preventive and screening strategies for this condition.Thisstudy evaluated the potential applications of wrist pulse detection technology for the early detection of liverdiseases.The pulse time-domain features of a medical exam population with and without hepatic steatosis wereassessed to develop a screening model for this disease.Methods Participants were consecutively recruited from March 2021 to March 2022 in the medical examinationcenters of the Yueyang Hospital of Integrated Traditional Chinese and Western Medicine and the Shanghai Municipal Hospital of Traditional Chinese Medicine.Clinical data from 255 participants,including general information(sex,age,and body mass index),and data related to glucose and blood lipids(fasting plasma glucose,triglyceride,total cholesterol,high-density lipoprotein,and low-density lipoprotein levels)were collected.Wrist pulse signalswere acquired using a pulse detection device,and the pulse time-domain features,including t_(1),t_(4),t_(5),T,w_(1),w_(2),h_(2)/h_(1),h_(3)/h_(1),and h5/h_(1) were extracted.Participants were assigned to hepatic steatosis and non-hepatic steatosisgroups according to their abdominal ultrasound examination results.Their clinical data and pulse time-domainfeatures were compared using chi-square and parametric or non-parametric statistical methods.Three datasetswere used to construct screening models for hepatic steatosis based on the random forest algorithm.The datasetsfor modeling were defined as Dataset 1,containing blood glucose and lipid data and general information;Dataset2,containing time-domain features and general information;Dataset 3,containing time-domain features,bloodglucose and lipid data,and general information.The evaluation metrics,accuracy,precision,recall,F1-score,andareas under the receiver operating characteristic curve(AUC)were compared for each model.Results The time-domain features of the two groups differed significantly.The t_(1),t_(4),t_(5),T,h_(2)/h_(1),h_(3)/h_(1),w_(1),and w_(2) features were higher in the hepatic steatosis group than in the non-hepatic steatosis group(P<0.05),while the h5/h_(1) features were lower in the hepatic steatosis group than in the non-hepatic steatosis group(P<0.05).The screening models for hepatic steatosis based on both time-domain features and blood glucose andlipid data outperformed those based on time-domain features or blood markers alone.The accuracy,precision,recall,F1-score,and AUC of the combined model were 81.18%,80.56%,76.32%,79%,and 87.79%,respectively.These proportions were 1.57%,1.86%,1.76%,2%,and 3.54%higher,respectively,than those of the model basedon time-domain features alone and 3.14%,4.2%,2.64%,4%,and 6.47%higher,respectively,than those of themodel based on blood glucose and lipid alone.Conclusion The early screening model for hepatic steatosis using datasets that included pulse time-domainfeatures achieved better performance.The findings suggest that pulse detection technology could be used toinform the development of a mobile medical device or remote home monitoring system to test for hepatitissteatosis.

Application Strategy of CBR Test in Highway Engineering

California Bearing Ratio(CBR)test is highly professional and requires a high level of skills.In order to improve the accuracy of the test results,the relevant staff will not only need to understand the rules and procedures involved in the test,they would also need to be meticulous in their work to avoid human errors,provide good data support for highway engineering,and improve the overall quality of the project.Therefore,this paper presents an analysis of the application of CBR test in highway engineering,which can provide reference for engineering and promote the development of the highway industry.

Research hotspot and frontier progress of cancer under the background of precision medicine

The timely introduction and rapid development of precision medicine have provided strong theoretical support and technical support for tumor research.The treatment methods have been developed from single to multiple;the research technology has been transformed from macro to micro;the treatment drugs have been updated from systemic chemotherapy to targeted therapy and immunotherapy,and cancer has changed from a highly lethal disease to a"chronic disease".Based on the current international cancer research hotspots and treatment frontiers,this paper takes stock from five aspects,namely,treatment methods,detection technology,new drug research and development,information data and traditional Chinese medicine,with a view to"from the point to the surface","from the outside to the inside",and"the combination of Chinese and western",so as to explore the overall picture of cancer treatment and research.

In-Flight Total Dose Estimation Using RADEM Instrument on JUICE

Missions flying to giant planets frequently provide telemetry data after substantial time lag. Determination of crucial environmental characteristic sometimes detrimental for the mission health may be further delayed by duration of subsequent data analysis. We propose a fast method used in-flight to assess the electron total ionizing dose and dose rate onboard of the JUICE ESA mission to JUPITER. The procedure provides estimated values of dose rate behind various thickness of shielding using counting rates from the electron telescope EHD of the RADEM radiation hard electron monitor instrument onboard JUICE.

A Review on the Research of Precision Medicine for Cancer Based on the Integration of Traditional Chinese and Western Medicine

Objective:To summarize and expound the general situation of precision medicine for cancer according to the current international research hot spots and treatment frontiers of cancer.Methods:This article makes an inventory from five aspects of treatment methods,detection technology,new drug research and development,information data and traditional Chinese medicine,"from point to surface","from outside to inside"and"integration of Chinese and Western medicine",to explore the whole picture of tumor treatment and research.Results:With the rapid development of tumor precision medicine in recent years,the tumor treatment methods have been developed from single to multiple.The research technology has been changed from macro to micro.The therapeutic drugs have been changed from systemic chemotherapy to targeted therapy,immunotherapy and other technologies.The treatment concept has been changed from local to overall.And the integrated treatment methods of traditional Chinese and Western medicine have brought a new chapter to tumor treatment.Conclusion:Through a series of new technologies,new methods and new concepts,tumor precision medicine promotes the treatment of tumors with integrated Chinese and Western medicine into a new chapter.

Tech to Protect Football Players' Heads--Technology Emerging to Detect and Prevent Concussions' in Football

头球是足球比赛中有力的得分手段,前德国国脚比埃尔霍夫就以头球著称。但医学研究发现,头球有可能导致颈部和头部损伤,并引发脑损伤,轻者引起人的轻微不适,重者则会危及生命。如果国际足联无法禁止头球,那么应该如何有效地保护、并且最大限度地降低头球给运动员的大脑带来的损伤程度呢?

A muon high-resolution pseudorange measurement method: Application to muon navigation in confined spaces

Confined spaces such as polar regions, deep earth and deep ocean are crucial navigation scenarios where traditional navigation techniques have difficulty in obtaining external signals for positioning. The cosmic ray muons, which carry the spatial and energetic information, are easy to penetrate these confined spaces. Therefore, the unique muon characteristic provides a new perspective to estimate detector position, which can be considered using in confined spaces navigation.In this paper, a well-developed theory of muon navigation is established by combining a muon pseudorange measurement method. Moreover, an Equivalent Velocity Calculation Model(EVCM)and a Muon Sequence Matching Technology(MSMT) are proposed. The first model corrects flight pseudorange error caused by the relativistic energy loss and the second technology compensates the random error in pseudorange measurement. Further, a series of simulations are performed to analyze the muon events number which can be received by detector in different scenarios with the variations of zenith angle, detector area, varied detector plates gap, and muon flight distance.Meanwhile, the simulation results demonstrate that the muon navigation update rate every 10 minutes can reach 5.989 in confined spaces at 100 m, and further pseudorange error analysis indicates that the meter-level positioning accuracy can be acquired. Finally, we construct a muon coincidence measurement scheme and verify that the laws of the muon positioning system for high-energy muons are consistent with the simulation results.

Complex heterozygous mutations in hereditary spherocytosis:A case report

BACKGROUND The aim of this study was to investigate the complex heterozygous mutations of ANK1 and SPTA1 in the same individual and improve our understanding of hereditary spherocytosis(HS)in children.We also hope to promote the application of gene detection technology in children with HS,with the goals of identifying more related gene mutations,supporting the acquisition of improved molecular genetic information to further reveal the pathogenesis of HS in children,and providing important guidance for the diagnosis,treatment,and prevention of HS in children.CASE SUMMARY A 1-year and 5-month-old patient presented jaundice during the neonatal period,mild anemia 8 months later,splenic enlargement at 1 year and 5 months,and brittle red blood cell permeability.Genetic testing was performed on the patient,their parents,and sister.Swiss Model software was used to predict the protein structure of complex heterozygous mutations in ANK1 and SPTA1.Genetic testing revealed that the patient harbored a new mutation in the ANK1 gene from the father and a mutation in the SPTA1 gene from the mother.Combined with the clinical symptoms of the children,it is suggested that the newly discovered complex heterozygous mutations of ANK1 and SPTA1 may be the cause,providing important guidance for revealing the pathogenesis,diagnosis,treatment,and promotion of gene detection technology in children with HS.CONCLUSION This case involves an unreported complex heterozygous mutation of ANK1 and SPTA1,which provides a reference for exploring HS.