The advancement of navigation systems for the visually impaired has significantly enhanced their mobility by mitigating the risk of encountering obstacles and guiding them along safe,navigable routes.Traditional appro...The advancement of navigation systems for the visually impaired has significantly enhanced their mobility by mitigating the risk of encountering obstacles and guiding them along safe,navigable routes.Traditional approaches primarily focus on broad applications such as wayfinding,obstacle detection,and fall prevention.However,there is a notable discrepancy in applying these technologies to more specific scenarios,like identifying distinct food crop types or recognizing faces.This study proposes a real-time application designed for visually impaired individuals,aiming to bridge this research-application gap.It introduces a system capable of detecting 20 different food crop types and recognizing faces with impressive accuracies of 83.27%and 95.64%,respectively.These results represent a significant contribution to the field of assistive technologies,providing visually impaired users with detailed and relevant information about their surroundings,thereby enhancing their mobility and ensuring their safety.Additionally,it addresses the vital aspects of social engagements,acknowledging the challenges faced by visually impaired individuals in recognizing acquaintances without auditory or tactile signals,and highlights recent developments in prototype systems aimed at assisting with face recognition tasks.This comprehensive approach not only promises enhanced navigational aids but also aims to enrich the social well-being and safety of visually impaired communities.展开更多
Based on the asymptotic spectral distribution of Wigner matrices, a new normality test method is proposed via reforming the white noise sequence. In this work, the asymptotic cumulative distribution function （CDF） o...Based on the asymptotic spectral distribution of Wigner matrices, a new normality test method is proposed via reforming the white noise sequence. In this work, the asymptotic cumulative distribution function （CDF） of eigenvalues of the Wigner matrix is deduced. A numerical Kullback-Leibler divergence of the empiric-d spectral CDF based on test samples from the deduced asymptotic CDF is established, which is treated as the test statistic. For validating the superiority of our proposed normality test, we apply the method to weak SIPSK signal detection in the single-input single-output （SISO） system and the single-input multiple-output （SIMO） system. By comparing with other common normality tests and the existing signal detection methods, simulation results show that the proposed method is superior and robust.展开更多
An in situ hybridization technique with 35S labelled proto-oncogene probes (c-myc & c-fes) was used to detect their expression in bone marrow cells of 22 cases of leukemia of various types and immature granulocyte...An in situ hybridization technique with 35S labelled proto-oncogene probes (c-myc & c-fes) was used to detect their expression in bone marrow cells of 22 cases of leukemia of various types and immature granulocytes and erythroblasts of 16 nomal myelograms as controls. Both c-myc and c-fes were detectable in leukemic cells as well as in immature granulocytes and erythroblasts of normal bone marrow, but the expression extent varied in different cases. The levels of c-myc expression in leukemic cells were higher than those in controls (P<0.001). There was no difference of c-fes expression in two groups of bone marrow cells (P>0.05). This technique provides us a new method in studying variations of proto-oncogene expression in leukemic cells.展开更多
A concise fractional Fourier transform （CFRFT） is proposed to detect the linear frequency-modulated （LFM） signal with low signal to noise ratio （SNR）. The frequency axis in time-frequency plane of the CFRFT is r...A concise fractional Fourier transform （CFRFT） is proposed to detect the linear frequency-modulated （LFM） signal with low signal to noise ratio （SNR）. The frequency axis in time-frequency plane of the CFRFT is rotated to get the spectrum of the signal in different an- gles using chirp multiplication and Fourier transform （FT）. For LFM signal which distributes as a straight line in time-frequency plane, the CFRFT can gather the energy in the corresponding angle as a peak and improve the detection SNR, thus the LFM signal of low SNR can be de- tected. Meanwhile, the location of the peak value relates to the parameters of the LFM signal. Numerical simulations and experimental results show that, the proposed method can be used to efficiently detect the LFM signal masked by noise and to estimate the signal＇s parameters accurately. Compared with the conventional fractional Fourier transform （FRFT）, the CFRFT reduces the transform complexity and improves the real-time detection performance of LFM signal.展开更多
Regarding the performance of traditional endpoint detection algorithms degrades as the environment noise level increases, a recursive calculating algorithm for higher-order cu- mulants over a sliding window is propose...Regarding the performance of traditional endpoint detection algorithms degrades as the environment noise level increases, a recursive calculating algorithm for higher-order cu- mulants over a sliding window is proposed. Then it is applied to the speech endpoint detection. Furthermore, endpoint detection is carried out with the feature of energy. Experimental results show that both the computational efficiency and the robustness against noise of the proposed algorithm are improved remarkably compared with traditional algorithm. The average prob- ability of correct point detection （Pc-point） of the proposed voice activity detection （VAD） is 6.07% higher than that of G.729b VAD in different noisy at different signal-noise ratios （SNRs） environments.展开更多
The ultrasonic testing for the defects of complete disbond in multi-layered structure with lower acoustic impedance beneath a high acoustic impedance overburden is one of the difficult problems in ultrasonic nondestru...The ultrasonic testing for the defects of complete disbond in multi-layered structure with lower acoustic impedance beneath a high acoustic impedance overburden is one of the difficult problems in ultrasonic nondestructive testing field. A model of a multi-layered steel-rubber composite plate is depicted. Because the acoustic impedance of the steel differs far from that of the couplant water and the rubber, the energy of the signal reflected from the debonded rubber layers is very weak. More over, the flaw echoes are masked by the strong echoes reverberated in the steel plate. It's nearly impossible to identify the debonding echoes directly. The subband adaptive filtering method is discussed in the paper, where the subband decomposition is performed by mutual wavelet packets decomposition on the criterion of maximizing the cross-correlation between the signals. The simulations on both synthetic and real signals are presented. The echoes from the delaminated flaw at the depth of 5 mm in the rubber from the calculated signal, and echoes from the flaw at the depth of 3 mm from the real signal are extracted successfully.展开更多
PKHD1 gene mutations are found responsible for autosomal recessive polycystic kidney disease（ARPKD）. However, it is inconvenient to detect the mutations by common polymerase chain reaction（PCR） because the open re...PKHD1 gene mutations are found responsible for autosomal recessive polycystic kidney disease（ARPKD）. However, it is inconvenient to detect the mutations by common polymerase chain reaction（PCR） because the open reading frame of PKHD1 is very long. Recently, long-range（LR） PCR is demonstrated to be a more sensitive mutation screening method for PKHD1 by directly sequencing. In this study, the entire PKHD1 coding region was amplified by 29 reactions to avoid the specific PCR amplification of individual exons, which generated the size of 1 to 7 kb products by LR PCR. This method was compared to the screening method with standard direct sequencing of each individual exon of the gene by a reference laboratory in 15 patients with ARPKD. The results showed that a total of 37 genetic changes were detected with LR PCR sequencing, which included 33 variations identified by the reference laboratory with standard direct sequencing. LR PCR sequencing had 100% sensitivity, 96% specificity, and 97.0% accuracy, which were higher than those with standard direct sequencing method. In conclusion, LR PCR sequencing is a reliable method with high sensitivity, specificity and accuracy for detecting genetic variations. It also has more intronic coverage and lower cost, and is an applicable clinical method for complex genetic analyses.展开更多
Conglutinin was extracted and purified from bovine’s sera and was used in ELISA for the detection of circulating immune complexes in the sera of patients suffering from epidemic hemorrhagic fever (EHF). The detected ...Conglutinin was extracted and purified from bovine’s sera and was used in ELISA for the detection of circulating immune complexes in the sera of patients suffering from epidemic hemorrhagic fever (EHF). The detected rates of circu-展开更多
基金supported by theKorea Industrial Technology Association(KOITA)Grant Funded by the Korean government(MSIT)(No.KOITA-2023-3-003)supported by the MSIT(Ministry of Science and ICT),Korea,under the ITRC(Information Technology Research Center)Support Program(IITP-2024-2020-0-01808)Supervised by the IITP(Institute of Information&Communications Technology Planning&Evaluation)。
文摘The advancement of navigation systems for the visually impaired has significantly enhanced their mobility by mitigating the risk of encountering obstacles and guiding them along safe,navigable routes.Traditional approaches primarily focus on broad applications such as wayfinding,obstacle detection,and fall prevention.However,there is a notable discrepancy in applying these technologies to more specific scenarios,like identifying distinct food crop types or recognizing faces.This study proposes a real-time application designed for visually impaired individuals,aiming to bridge this research-application gap.It introduces a system capable of detecting 20 different food crop types and recognizing faces with impressive accuracies of 83.27%and 95.64%,respectively.These results represent a significant contribution to the field of assistive technologies,providing visually impaired users with detailed and relevant information about their surroundings,thereby enhancing their mobility and ensuring their safety.Additionally,it addresses the vital aspects of social engagements,acknowledging the challenges faced by visually impaired individuals in recognizing acquaintances without auditory or tactile signals,and highlights recent developments in prototype systems aimed at assisting with face recognition tasks.This comprehensive approach not only promises enhanced navigational aids but also aims to enrich the social well-being and safety of visually impaired communities.
基金Supported by the National Natural Science Foundation of China under Grant No 61371170the Fundamental Research Funds for the Central Universities under Grant Nos NP2015404 and NS2016038+1 种基金the Aeronautical Science Foundation of China under Grant No 20152052028the Funding of Jiangsu Innovation Program for Graduate Education under Grant No KYLX15_0282
文摘Based on the asymptotic spectral distribution of Wigner matrices, a new normality test method is proposed via reforming the white noise sequence. In this work, the asymptotic cumulative distribution function （CDF） of eigenvalues of the Wigner matrix is deduced. A numerical Kullback-Leibler divergence of the empiric-d spectral CDF based on test samples from the deduced asymptotic CDF is established, which is treated as the test statistic. For validating the superiority of our proposed normality test, we apply the method to weak SIPSK signal detection in the single-input single-output （SISO） system and the single-input multiple-output （SIMO） system. By comparing with other common normality tests and the existing signal detection methods, simulation results show that the proposed method is superior and robust.
文摘An in situ hybridization technique with 35S labelled proto-oncogene probes (c-myc & c-fes) was used to detect their expression in bone marrow cells of 22 cases of leukemia of various types and immature granulocytes and erythroblasts of 16 nomal myelograms as controls. Both c-myc and c-fes were detectable in leukemic cells as well as in immature granulocytes and erythroblasts of normal bone marrow, but the expression extent varied in different cases. The levels of c-myc expression in leukemic cells were higher than those in controls (P<0.001). There was no difference of c-fes expression in two groups of bone marrow cells (P>0.05). This technique provides us a new method in studying variations of proto-oncogene expression in leukemic cells.
基金supported by the National Natural Science Foundation of China(11434012)
文摘A concise fractional Fourier transform （CFRFT） is proposed to detect the linear frequency-modulated （LFM） signal with low signal to noise ratio （SNR）. The frequency axis in time-frequency plane of the CFRFT is rotated to get the spectrum of the signal in different an- gles using chirp multiplication and Fourier transform （FT）. For LFM signal which distributes as a straight line in time-frequency plane, the CFRFT can gather the energy in the corresponding angle as a peak and improve the detection SNR, thus the LFM signal of low SNR can be de- tected. Meanwhile, the location of the peak value relates to the parameters of the LFM signal. Numerical simulations and experimental results show that, the proposed method can be used to efficiently detect the LFM signal masked by noise and to estimate the signal＇s parameters accurately. Compared with the conventional fractional Fourier transform （FRFT）, the CFRFT reduces the transform complexity and improves the real-time detection performance of LFM signal.
基金supported by the National Natural Science Eoundation of China(61271352)
文摘Regarding the performance of traditional endpoint detection algorithms degrades as the environment noise level increases, a recursive calculating algorithm for higher-order cu- mulants over a sliding window is proposed. Then it is applied to the speech endpoint detection. Furthermore, endpoint detection is carried out with the feature of energy. Experimental results show that both the computational efficiency and the robustness against noise of the proposed algorithm are improved remarkably compared with traditional algorithm. The average prob- ability of correct point detection （Pc-point） of the proposed voice activity detection （VAD） is 6.07% higher than that of G.729b VAD in different noisy at different signal-noise ratios （SNRs） environments.
基金This work was supported by the National Science Foundation of China (No. 19974063) and the President Foundation of the Institute of Acoustics, Chinese Academy of Sciences.
文摘The ultrasonic testing for the defects of complete disbond in multi-layered structure with lower acoustic impedance beneath a high acoustic impedance overburden is one of the difficult problems in ultrasonic nondestructive testing field. A model of a multi-layered steel-rubber composite plate is depicted. Because the acoustic impedance of the steel differs far from that of the couplant water and the rubber, the energy of the signal reflected from the debonded rubber layers is very weak. More over, the flaw echoes are masked by the strong echoes reverberated in the steel plate. It's nearly impossible to identify the debonding echoes directly. The subband adaptive filtering method is discussed in the paper, where the subband decomposition is performed by mutual wavelet packets decomposition on the criterion of maximizing the cross-correlation between the signals. The simulations on both synthetic and real signals are presented. The echoes from the delaminated flaw at the depth of 5 mm in the rubber from the calculated signal, and echoes from the flaw at the depth of 3 mm from the real signal are extracted successfully.
基金supported by grants from the Hubei Provincial Natural Science Foundation of China(No.2010CDB-06903)National Key Basic Research Program of China(“973”Program,No.2012CB526706)the National Natural Science Foundation of China(Nos.81000771 and 81271694)
文摘PKHD1 gene mutations are found responsible for autosomal recessive polycystic kidney disease（ARPKD）. However, it is inconvenient to detect the mutations by common polymerase chain reaction（PCR） because the open reading frame of PKHD1 is very long. Recently, long-range（LR） PCR is demonstrated to be a more sensitive mutation screening method for PKHD1 by directly sequencing. In this study, the entire PKHD1 coding region was amplified by 29 reactions to avoid the specific PCR amplification of individual exons, which generated the size of 1 to 7 kb products by LR PCR. This method was compared to the screening method with standard direct sequencing of each individual exon of the gene by a reference laboratory in 15 patients with ARPKD. The results showed that a total of 37 genetic changes were detected with LR PCR sequencing, which included 33 variations identified by the reference laboratory with standard direct sequencing. LR PCR sequencing had 100% sensitivity, 96% specificity, and 97.0% accuracy, which were higher than those with standard direct sequencing method. In conclusion, LR PCR sequencing is a reliable method with high sensitivity, specificity and accuracy for detecting genetic variations. It also has more intronic coverage and lower cost, and is an applicable clinical method for complex genetic analyses.
文摘Conglutinin was extracted and purified from bovine’s sera and was used in ELISA for the detection of circulating immune complexes in the sera of patients suffering from epidemic hemorrhagic fever (EHF). The detected rates of circu-
