Exploring well-being disparities between urban and rural areas:A case study in the Stavropol Territory,Russia

Rural areas are crucial for a country’s sustainable economy.New strategies are needed to develop rural areas to improve the well-being of rural population and generate new job opportunities.This is especially important in countries where agricultural production accounts for a significant share of the gross product,such as Russia.In this study,we identified the key indicators of satisfaction and differences between rural and urban citizens based on their social,economic,and environmental backgrounds,and determined whether there are well-being disparities between rural and urban areas in the Stavropol Territory,Russia.We collected primary data through a survey based on the European Social Survey framework to investigate the potential differences between rural and urban areas.By computing the regional well-being index using principal component analysis,we found that there was no statistically significant difference in well-being between rural and urban areas.Results of key indicators showed that rural residents felt psychologically more comfortable and safer,assessed their family relationships better,and adhered more to traditions and customs.However,urban residents showed better economic and social conditions(e.g.,infrastructures,medical care,education,and Internet access).The results of this study imply that we can better understand the local needs,advantages,and unique qualities,thereby gaining insight into the effectiveness of government programs.Policy-makers and local authorities can consider targeted interventions based on the findings of this study and strive to enhance the well-being of both urban and rural residents.

Women health and microbiota:Different aspects of well-being

In this editorial,we comment on the article by Marano et al recently published in the World Journal of Gastroenterology 2023;29(45):5945-5952.We focus on the role of gut microbiota(GM)in women’s health,highlighting the need to thoroughly comprehend the sex differences in microbiota.Together,the host and GM support the host’s health.The microbiota components consist of viruses,bacteria,fungi,and archaea.This complex is an essential part of the host and is involved in neu-rological development,metabolic control,immune system dynamics,and host dynamic homeostasis.It has been shown that differences in the GM of males and females can contribute to chronic diseases,such as gastrointestinal,metabolic,neurological,cardiovascular,and respiratory illnesses.These differences can also result in some sex-specific changes in immunity.Every day,research on GM reveals new and more expansive frontiers,offering a wealth of innovative oppor-tunities for preventive and precision medicine.

Relationship Between Individuals’Epidemic Risk Perception Within Living Space and Subjective Well-Being:Empirical Evidence from China after the First Wave of COVID-19

It is common to observe the epidemic risk perception(ERP)and a decline in subjective well-being(SWB)in the context of public health events,such as Corona Virus Disease 2019(COVID-19).However,there have been few studies exploring the impact of individuals’ERP within living space on their SWB,especially from a geographical and daily activity perspective after the resumption of work and other activities following a wave of the pandemic.In this paper,we conducted a study with 789 participants in urban China,measuring their ERP within living space and examining its influence on their SWB using path analysis.The results indicated that individuals’ERP within their living space had a significant negative effect on their SWB.The density of certain types of facilities within their living space,such as bus stops,subway stations,restaurants,fast food shops,convenience shops,hospitals,and public toilets,had a significantly negative impact on their SWB,mediated by their ERP within living space.Additionally,participation in out-of-home work and other activities not only increased individuals’ERP within living space,but also strengthened its negative effect on their SWB.

Self-Compassion Moderates the Effect of Contingent Self-Esteem on Well-Being:Evidence from Cross-Sectional Survey and Experiment

Contingent self-esteem captures the fragile nature of self-esteem and is often regarded as suboptimal to psychological functioning.Self-compassion is another important self-related concept assumed to promote mental health and well-being.However,research on the relation of self-compassion to contingent self-esteem is lacking.Two studies were conducted to explore the role of selfcompassion,either as a personal characteristic or an induced mindset,in influencing the effects of contingent self-esteem on well-being.Study 1 recruited 256 Chinese college students(30.4%male,mean age=21.72 years)who filled out measures of contingent self-esteem,self-compassion,and well-being.The results found that self-compassion moderated the effect of contingent self-esteem on well-being.In Study 2,a sample of 90 Chinese college students(34%male,mean age=18.39 years)were randomly assigned to either a control or self-compassion group.They completed baseline trait measures of contingent self-esteem,self-compassion,and self-esteem.Then,they were led to have a 12-min break(control group)or listen to a 12-min self-compassion audio(self-compassion group),followed by a social stress task and outcome measures.The results demonstrated the effectiveness of the brief self-compassion training and its moderating role in influencing the effects of contingent self-esteem on negative affects after the social stress task.This research provides implications that to equip with a self-compassionate mindset could lower the risk of the impairment of well-being associated with elements of contingent selfesteem,which involves a fragile sense of self-worth.It may also provide insights into the development of an“optimal selfesteem”and the improvement of well-being.

Disparities in the impact of economic well-being on self-esteem in adulthood:Race and ethnicity

BACKGROUND Most studies have defined economic well-being as socioeconomic status,with little attention given to whether other indicators influence self-esteem.Little is known about racial/ethnic disparities in the relationship between economic wellbeing and self-esteem during adulthood.AIM To explore the impact of economic well-being on self-esteem in adulthood and differences in the association across race/ethnicity.METHODS The current study used data from the National Longitudinal Survey of Youth 1979.The final sample consisted of 2267 African Americans,1425 Hispanics,and 3678 non-Hispanic Whites.Ordinary linear regression analyses and logistic regression analyses were conducted.RESULTS African Americans and Hispanics were more likely to be in poverty in comparison with non-Hispanic Whites.More African Americans were unemployed than Whites.Those who received fringe benefits,were more satisfied with jobs,and were employed were more likely to have higher levels of self-esteem.Poverty was negatively associated with self-esteem.Interaction effects were found between African Americans and job satisfaction predicting self-esteem.CONCLUSION The role of employers is important in cultivating employees’self-esteem.Satisfactory outcomes or feelings of happiness from the workplace may be more important to non-Hispanic Whites compared to African Americans and Hispanics.

Single-cell profiling of the pig cecum at various developmental stages

The gastrointestinal tract is essential for food digestion,nutrient absorption,waste elimination,and microbial defense.Single-cell transcriptome profiling of the intestinal tract has greatly enriched our understanding of cellular diversity,functional heterogeneity,and their importance in intestinal tract development and disease.Although such profiling has been extensively conducted in humans and mice,the single-cell gene expression landscape of the pig cecum remains unexplored.Here,single-cell RNA sequencing was performed on 45572 cells obtained from seven cecal samples in pigs at four different developmental stages(days(D)30,42,150,and 730).Analysis revealed 12 major cell types and 38 subtypes,as well as their distinctive genes,transcription factors,and regulons,many of which were conserved in humans.An increase in the relative proportions of CD8^(+)T and Granzyme A(low expression)natural killer T cells(GZMA^(low)NKT)cells and a decrease in the relative proportions of epithelial stem cells,Tregs,RHEX^(+)T cells,and plasmacytoid dendritic cells(pDCs)were noted across the developmental stages.Moreover,the post-weaning period exhibited an up-regulation in mitochondrial genes,COX2 and ND2,as well as genes involved in immune activation in multiple cell types.Cell-cell crosstalk analysis indicated that IBP6^(+)fibroblasts were the main signal senders at D30,whereas IBP6^(−)fibroblasts assumed this role at the other stages.NKT cells established interactions with epithelial cells and IBP6^(+)fibroblasts in the D730 cecum through mediation of GZMA-F2RL1/F2RL2 pairs.This study provides valuable insights into cellular heterogeneity and function in the pig cecum at different development stages.

A Review of Western and Eastern Traditional Views of Well-Being

This paper reviews traditional understanding of well-being from both Western and Eastern cultural perspectives. First, two distinct Western traditions in defining well-being are compared, namely hedonic and eudaemonic approaches. The hedonic approach defines happiness as the maximization of pleasure, while the eudaemonic approach regards happiness as the fulfillment of a person’s natural needs and overall flourishing. Second, the views of well-being in lens of Confucianism, Buddhism, and Taoism in the East are reviewed. The common and different understandings of well-being between Western and Eastern traditions are discussed as followed. Finally, two well-known operationalized definitions of well-being, that is subjective well-being and psychological well-being, proposed in the roots of Western traditions are elucidated.

Treatment of bilateral developmental dysplasia of the hip joint with an improved technique:A case report

BACKGROUND Developmental dysplasia of the hip(DDH)is a common osteoarticular deformity in pediatric orthopedics.A patient with bilateral DDH was diagnosed and treated using our improved technique"(powerful overturning acetabuloplasty)"combined with femoral rotational shortening osteotomy.CASE SUMMARY A 4-year-old girl who was diagnosed with bilateral DDH could not stand normally,and sought surgical treatment to solve the problem of double hip extension and standing.As this child had high dislocation of the hip joint and the acetabular index was high,we changed the traditional acetabuloplasty to"powerful turnover acetabuloplasty"combined with femoral rotation shortening osteotomy.During the short-term postoperative follow-up(1,3,6,9,12,and 15 months),the child had no discomfort in her lower limbs.After the braces and internal fixation plates were removed,formal rehabilitation training was actively carried out.CONCLUSION Our"powerful overturning acetabuloplasty"combined with femoral rotational shortening osteotomy is feasible in the treatment of DDH in children.This technology may be widely used in the clinic.

Economic Resilience in Bangladesh: Analyzing Household Well-Being amidst Price Hikes through ANOVA and Paired Sample t-Test Insights

This study delves into the multifaceted impact of price hikes on the standard of living in Bangladesh, with a specific focus on distinct socioeconomic segments. Amidst Bangladesh’s economic growth, the challenges of rising inflation and increased living costs have become pressing concerns. Employing a mixed-methods approach combines quantitative data from a structured survey with qualitative insights from in-depth interviews and focused group discussions to analyze the repercussions of price hikes. Stratified random sampling ensures representation across affluent, middle-class, and economically disadvantaged groups. Utilizing data [1] from 2020 to November 2023 on the yearly change in retail prices of essential commodities, analysis reveals significant demographic shifts, occupational changes, and altered asset ownership patterns among households. The vulnerable population, including daily wage laborers and low-income individuals, is disproportionately affected by adjustments in consumption, income generation, and living arrangements. Statistical analyses, including One-Way ANOVA and Paired Sample t-tests, illuminate significant mean differences in strategies employed during price hikes. Despite challenges, the prioritization of education remains evident, emphasizing its resilience in the face of economic hardships. The result shows that price hikes, especially in essential items, lead to substantial adjustments in living costs, with items like onions, garlic, and ginger experiencing significant increases of 275%, 108%, and 483%, respectively.

Bibliographical Review on Rehabilitation of Executive Functions in Patients With Developmental Coordination Disorder(DCD)

The present study aims to establish a literature review on intervention programs for executive functions(EFs)through the use of fundamental motor skills,from a neuropsychopedagogical perspective in subjects with Developmental Coordination Disorder(DCD).An exploratory study was carried out through an integrative literature review.The research was carried out in the Scientific databases Electronic Library Online(SciELO),Latin American and Caribbean Literature in Health Sciences(LILACS),Virtual Health Library-Psychology Brazil(BVSPSI),Electronic Journals of Psychology(PePSIC),in the periodicals available in the Brazilian Digital Library of Theses and Dissertations(BDTD)and on the website of the Coordination for the Improvement of Higher Education Personnel(CAPES).The covering publications took place from 2018 to 2023,14 articles were selected for analysis.This literature review made it possible to create strategies for stimulating EF and Visuomotor Functions so that educators and other professionals can better deal with students with DCD.It was perceived the need to carry out and develop more empirical research regarding the intervention of EFs and Visuomotor Functions by educators and professionals,with a greater sampling amplitude,to increase the number of studies that enable interventions both in children and in teenagers with DCD.

The Relationship between Mental Health Literacy and Subjective Well-Being of Young and Middle-Aged Residents: Perceived the Mediating Role of Social Support and Its Urban-Rural Differences

This study investigates mental health literacy among young and middle-aged urban and rural residents and the differences in mental health literacy,perceived social support and subjective well-being.From January to February 2022,620 participants(320 rural and 300 urban residents)from three provinces of China were selected by con-venience sampling.A general data questionnaire,mental health literacy scale,perceived social support scale and subjective well-being scale were administered.The mental health literacy scores of urban residents were 3.34±0.57 and those of rural residents were 2.73±0.79.The results of multiple regression analysis showed that the mental health literacy scores of rural residents were more significant than those of urban residents in terms of sex and age,while urban residents’mental health literacy scores were more significant than those of rural resi-dents in terms of monthly income.Mental health literacy,perceived social support and subjective well-being of young and middle-aged urban and rural residents were all positively correlated(P<0.01).While the level of mental health literacy is better among urban residents than rural residents,perceived social support plays a partial mediating role between mental health literacy and subjective well-being of both urban and rural residents,and should be the focus of researchers seeking to improve the level of well-being of residents.

Effects of different pelvic osteotomies on acetabular morphology in developmental dysplasia of hip in children

Developmental dysplasia of hip seriously affects the health of children,and pelvic osteotomy is an important part of surgical treatment.Improving the shape of the acetabulum,preventing or delaying the progression of osteoarthritis is the ultimate goal of pelvic osteotomies.Re-directional osteotomies,reshaping osteotomies and salvage osteotomies are the three most common types of pelvic osteotomy.The influence of different pelvic osteotomy on acetabular morphology is different,and the acetabular morphology after osteotomy is closely related to the prognosis of the patients.But there lacks comparison of acetabular morphology between different pelvic osteotomies,on the basis of retrospective analysis and measurable imaging indicators,this study predicted the acetabular shape after developmental dysplasia of the hip pelvic osteotomy in order to help clinicians make reasonable and correct decisions and improve the planning and performance of pelvic osteotomy.

Is there regional convergence between Morocco and its OECD partner countries in terms of well-being?

Morocco wants its 12 regions to play the role as the main lever of its public policies to initiate harmonized spatial multidimensional development. In the context of this goal and Morocco’s openness over the past two decades to bilateral and multilateral cooperation in an effort toward regional integration, this article studies the convergence of 389 regions in 36 countries(Morocco and 35 of its partner member countries in the Organization for Economic Co-operation and Development(OECD)) between 2000 and 2019 in terms of well-being. To this end, we considered the territorial dimension of β-convergence models for well-being and its four domains(economic, social, environmental, and governance). Then, we adapted the absolute β-convergence model by taking into account the existence of spatial heterogeneity according to five specifications of spatial models. Thus, apart from environmental domain, we found that β-convergence of regions is significant for well-being and three of its domains(economic, social, and governance). These convergences are made by a spatially autocorrelated error model(SEM). However, the speed and period of convergence are relatively low for social domain, partly explaining the very exacerbated tensions at the territorial level. The fastest convergence was achieved in governance domain, followed by economic domain. This suggests that emerging countries must pay particular attention to national public action in favor of social cohesion at the territorial level. The lack of convergence in environmental domain calls for common actions for all countries at the supranational level to protect the commons at the territorial level.

The Mediating Role of Religious Beliefs in the Relationship between Well-Being and Fear of the Pandemic

Religion is one of the social entities that has had a significant impact on the pandemic.The study’s goals are to investigate the relationship between well-being and fear of COVID-19,as well as to test whether religious beliefs mediate the effect of wellbeing on fear of COVID-19.The sample comprised of 433 participants in Vietnam.Independent Sample t-Test,One-way ANOVA,mediation analysis were used to analyze the data.In the levels of well-being,individuals who engage in religious services daily have higher levels than those hardly and never attend,and people from the age of 18 to 30 have higher levels than individuals from 31 to above 60 years.In addition,people aged from 51 to above 60 have higher levels of religious beliefs than people aged from 18 to 50.Females experience more fear of COVID-19 compared to males.The latter illustrates that religious beliefs mediate the effect of well-being on fear of COVID-19.Social workers and clinicians must prioritize older adults and people with chronic diseases for early mental interventions,and they should be aware of the role of religion in psychological treatment integration.

Exploring the Impact of Crisis and Trauma on the Mental Health and Psychological Well-Being of University Students in Northern Haiti

In recent decades,Haiti has been subject to man-made and natural disasters that have left its citizens vulnerable to a range of shocks.With a weak state unable to protect its populace,Haitians are exposed to some of the highest levels of poverty and violence in the Western Hemisphere.In recent years,Haitians have experienced two crises that this study analyzes:the instability and political violence of“peyi lòk”as well as the global pandemic of COVID-19.This community-based assessment explores the impact of these two crises on the mental health and psychological well-being of 38 Haitian university students in the understudied northern part of the country.Results indicate that both crises had similarities related to their psychological effects on young people,most notably in terms of traumatic experiences related to threats or violence,forced confinement,and large increases in population-wide uncertainty.Additionally,the extreme violence of“peyi lòk”and the widespread unpredictability of COVID-19 and its effects in the early days of the pandemic resulted in high levels of stress and fear.Both crises also resulted in extreme economic hardship for students,with many reporting difficulties accessing basic needs such as food and water.This study highlights how converging population-level crises in“complex emergencies”can heighten trauma and compromise mental health.

Children and Workers Well-Being in Belgian French-Speaking Primary Schools during the COVID-19 Pandemic

Purpose: During the COVID-19 pandemic, a significant number of measures were taken worldwide to limit the transmission of SARS-CoV-2, and in many ways, changed human life. All these measures had harmful consequences and impacted the well-being of many people. Children were one of the most vulnerable groups. We conducted the present study to assess children’s and staff’s well-being in French-speaking primary schools in Belgium during the COVID-19 pandemic. Methods: A 37-question questionnaire for each child based on the Revised Children’s Manifest Anxiety Scale (RCMAS), and a 14-question questionnaire for each staff based on the Hospital Anxiety and Depression (HAD) scale was undertaken in order to assess the well-being. Multiple logistic regressions were performed to assess the relationship between RCMAS or HAD and other explanatory variables. Staff reported their perception of their current life and their future life in 5 years on a Visual Analogue Scale (VAS). Results: A total of 231 children and 221 staff in 11 primary schools answered the well-being questionnaire between January and May 2021. 53% (122/231) of children had symptoms of anxiety. Girls reported more anxiety symptoms than boys (≥10: 59%;Adj OR = 2.25;95% CI [1.28;4.03]). 52% (120/231) of children had a definite state of social desirability. According to age, the youngest (6 - 7 years) children were more likely to have social desirability (≥5: 71%;Adj OR = 3.44;95% CI [1.53;8.09]) compared to the oldest (10 - 12 years). Children who did not practice outdoor/street activities were more likely to have social desirability (≥5: 60%;Adj OR = 2.59;95% CI [1.38;4.99]). In schools with a higher local incidence of SARS-CoV-2, children were more likely to have social desirability (≥5: 64%;Adj OR = 2.15;95% CI [1.13;4.17]). In schools with a lower socioeconomic status, children were more likely to have social desirability (≥5: 72%;Adj OR = 2.74;95% CI [1.23;6.37]). Higher RCMAS anxiety (r = −0.18;p −0.23;p −0.20;p Conclusion: Our results showed that the well-being of children was impacted during the COVID-19 pandemic. Special attention must be focused on the most vulnerable groups, as the consequences can be catastrophic in the long term.

A Study of Hie and LBP: The First Step to Improve Subjective Well-Being

Backgrounds: Health does not only physical health, therefore, we need to study it from various viewpoints. Many Japanese female complain of a Hie or a low back pain (LBP), which they reduce their subjective well-being. We analyze. Those patients often have acupuncture therapy. In this study, we analyze the characteristics of Hie and LBP, the satisfaction level of alternative therapy and we pursue a tip to improve subjective well-being. Methods: Of 1000 women, Hie (+)/Hie (−) or LBP (+)/LBP (−), we compared their body temperature (BT) (axilla) and body mass index (BMI). Furthermore, the Chi test identified ten factors of “body” and seven “mind” information. Results: In the result of BT (axilla) while LBP indicated a significant difference. Both Hie and LBP showed difference in the opposite direction. Hie did now show such clear differences in “body” information. However, interestingly, all seven questions in the “mind” information showed statistical difference. Discussion and conclusion: One reason why those patients have acupuncture therapy may acupuncture therapy traditionally has not separate “mind” and “body” and it has the concept of “mind-body unity”. To improve subjective well-being, first we need to focus on “Mind” as well as “mind-body unity”. Mental-health support is important for patients with Hie or LBP to reduce physiological stress.

Design of Multifunctional Milk Powder Spoon Based on Environment-friendly and Developmental Concept

Recycling of junks is positive for the environmental protection.Along with the proposal of three-child policy,purchase volume of milk powder surely will experience a drastic growth,and the milk powder spoon as an affiliated product will win the attention of parents.Against the background of consumption upgrading,consumers have had higher requirements on the humanization and safety design of products.Most of milk powder spoons on the market are plastic,and the disposal of waste milk powder spoon has gradually become a burden for the environment.Based on the environment-friendly and developmental concept,and also the characteristics of infant development,this paper proposed the“in-one”design,applied color and tactile designs into the milk powder design,chose food grade silicone to make the milk powder spoon not only a spoon but also a baby teether toy,so as to expand the service life and functions of the product,meet the requirements of saving energy,protecting environment and developing circular economy,which also to some extent reduces the burden on environment brought by plastics,improves the efficiency of junk recycling,and meet the individualized needs of consumers.

A perspective on molecular and cellular biology-based developmental toxicology biomarkers

The process of development is intricate and couple-dependent phenomenon.Accordingly,the study of molecular and cellular biology-based developmental toxicology biomarkers increasingly is becoming an important part of risk assessment and management of chemicals for detection of health outcomes and/or biological endpoint like cytotoxicity,cell death,etc.Since,the evolution of developmental toxicology field a number of tools/markers have been developed or addressed to deal with developmental outcomes,which can ultimately be used for the development of adverse outcome pathways(AOPs)of developmental toxicants.As a result,this paper provides an overview of the current state of developmental toxicology biomarkers and describes the strategies used in the selection and evaluation of such biomarkers in the context of developmental toxicity studies.Here,we discuss about the biological markers that are directly linked to developmental toxicity with respect to future revolutionary perspectives.Additionally,this chapter will address different associated outcomes of developmental exposure by intriguing advance techniques.The discussion focuses on the challenges associated with the development of biomarkers for developmental toxicity and highlights some of the recent advances in this area.Finally,the chapter concludes with a brief discussion of the future prospects for the use of molecular and cellular biology-based developmental toxicity biomarkers.Hope the present state of the art will provide a succinct summary of recent developments of biomarkers of developmental toxicology.

Anethole improves the developmental competence of porcine embryos by reducing oxidative stress via the sonic hedgehog signaling pathway

Background Anethole(AN)is an organic antioxidant compound with a benzene ring and is expected to have a positive impact on early embryogenesis in mammals.However,no study has examined the effect of AN on porcine embryonic development.Therefore,we investigated the effect of AN on the development of porcine embryos and the underlying mechanism.Results We cultured porcine in vitro-fertilized embryos in medium with AN(0,0.3,0.5,and 1 mg/mL)for 6 d.AN at 0.5 mg/mL significantly increased the blastocyst formation rate,trophectoderm cell number,and cellular survival rate compared to the control.AN-supplemented embryos exhibited significantly lower reactive oxygen species levels and higher glutathione levels than the control.Moreover,AN significantly improved the quantity of mitochondria and mitochondrial membrane potential,and increased the lipid droplet,fatty acid,and ATP levels.Interestingly,the levels of proteins and genes related to the sonic hedgehog(SHH)signaling pathway were significantly increased by AN.Conclusions These results revealed that AN improved the developmental competence of porcine preimplantation embryos by activating SHH signaling against oxidative stress and could be used for large-scale production of high-quality porcine embryos.