Acetone sensors for non-invasive diagnosis of diabetes based on metal-oxide-semiconductor materials

In recent years, clinical studies have found that acetone concentration in exhaled breath can be taken as a characteristic marker of diabetes. Metal-oxide-semiconductor (MOS) materials are widely used in acetone gas sensors due to their low cost, high sensitivity, fast response/recovery time, and easy integration. This paper reviews recent progress in acetone sensors based on MOS materials for diabetes diagnosis. The methods of improving the performance of acetone sensor have been explored for comparison, especially in high humidity conditions. We summarize the current excellent methods of preparations of sensors based on MOSs and hope to provide some help for the progress of acetone sensors in the diagnosis of diabetes.

Study on Key Biological Indicators of Diabetes Based on Statistical Tests

Normality testing is a fundamental hypothesis test in the statistical analysis of key biological indicators of diabetes.If this assumption is violated,it may cause the test results to deviate from the true value,leading to incorrect inferences and conclusions,and ultimately affecting the validity and accuracy of statistical inferences.Considering this,the study designs a unified analysis scheme for different data types based on parametric statistical test methods and non-parametric test methods.The data were grouped according to sample type and divided into discrete data and continuous data.To account for differences among subgroups,the conventional chi-squared test was used for discrete data.The normal distribution is the basis of many statistical methods;if the data does not follow a normal distribution,many statistical methods will fail or produce incorrect results.Therefore,before data analysis and modeling,the data were divided into normal and non-normal groups through normality testing.For normally distributed data,parametric statistical methods were used to judge the differences between groups.For non-normal data,non-parametric tests were employed to improve the accuracy of the analysis.Statistically significant indicators were retained according to the significance index P-value of the statistical test or corresponding statistics.These indicators were then combined with relevant medical background to further explore the etiology leading to the occurrence or transformation of diabetes status.

Diabetic Retinopathy Diagnosis Using ResNet with Fuzzy Rough C-Means Clustering

Diabetic Retinopathy(DR)is a vision disease due to the long-term prevalenceof Diabetes Mellitus.It affects the retina of the eye and causes severedamage to the vision.If not treated on time it may lead to permanent vision lossin diabetic patients.Today’s development in science has no medication to cureDiabetic Retinopathy.However,if diagnosed at an early stage it can be controlledand permanent vision loss can be avoided.Compared to the diabetic population,experts to diagnose Diabetic Retinopathy are very less in particular to local areas.Hence an automatic computer-aided diagnosis for DR detection is necessary.Inthis paper,we propose an unsupervised clustering technique to automatically clusterthe DR into one of its five development stages.The deep learning based unsupervisedclustering is made to improve itself with the help of fuzzy rough c-meansclustering where cluster centers are updated by fuzzy rough c-means clusteringalgorithm during the forward pass and the deep learning model representationsare updated by Stochastic Gradient Descent during the backward pass of training.The proposed method was implemented using python and the results were takenon DGX server with Tesla V100 GPU cards.An experimental result on the publicallyavailable Kaggle dataset shows an overall accuracy of 88.7%.The proposedmodel improves the accuracy of DR diagnosis compared to the existingunsupervised algorithms like k-means,FCM,auto-encoder,and FRCM withalexnet.