Analysis of The Effect of General Medicine-Based Education in Type 2 Diabetes Mellitus Patients in Neijiang City, China

Objective:To investigate and analyze the current situation of cognition,attitude,behavior,and influencing factors of Type 2 Diabetes Mellitus(T2DM)patients in Neijiang City,and to explore the effectiveness of the application of the education program based on the popularization of science in general medicine.Methods:Seventy cases of T2DM patients in Neijiang City were selected and randomly divided into 35 cases each in the observation group and the control group.The observation group received general medicine science education intervention and the control group received traditional health education.Indicators such as cognitive level,attitude,and behavioral change between the two groups were compared to assess the effect of general medical science education.Results:Before the intervention,there was no difference between the two groups in terms of knowledge,beliefs,and behaviors in general medicine,glycemic control,body mass index(BMI),and satisfaction with health education(P>0.05).After 3 months of the intervention,there was a highly significant difference in the aforementioned levels between the two groups(P<0.05).Conclusion:The approach of general medicine popularization had a significant effect on the treatment and management of T2DM patients in Neijiang City.It improved the patient’s cognitive level and self-management ability of the disease,increased their treatment adherence,and improved the therapeutic effect.

Rural Labor Force Transfer Training Effects Evaluation by Matching Methods: Evidence from Yunnan Province of China

Rural labor force transfer training is one of important poverty alleviation measures in China. This paper describes training participation situation and evaluates training effects by matching methods in the case of coastal autonomous minority nationality areas of Yunnan province by using 2053 rural household data. The result shows that the average training participation from 2006 to 2008 is 26.39 percent. In addition, ATE is 18.33 percent, TT is 18.99 percent, TUT is 18.09 percent. And,TUT . It demonstrates that the rural labor force transfer training program is effective and well-directed in coastal autonomous minority nationality areas of Yunnan province of China.

Analysis of Combined Therapy and Treatment Effect of Localized Ultraviolet Irradiation and Shengji Yuhong Cream on Diabetic Foot

Objective:To investigate the treatment effect of combined application of localized ultraviolet irradiation and Shengji Yuhong Cream on diabetic foot patients.Methods:Diabetic foot patients in the control group were treated with localized ultraviolet irradiation on the basis of conventional treatment.The study group was added with Shengji Yuhong Cream on top of the localized ultraviolet irradiation on the basis of conventional treatment.Results:The results of ankle brachial index and dorsal foot skin temperature of that two groups before treatment were compared,P>0.05.After treatment,the ankle brachial index and dorsal foot skin temperature of the study group were better than those of the control group.The comparison between the groups and within the group was P<0.05.The total effective rate of the study group(95.65%)was higher than that of the control group(71.11%),P<0.05.Conclusion:The application of localized ultraviolet irradiation and Shengji Yuhong Cream in the treatment of diabetic foot is effective.

Research Progress in the Effect Evaluation of GLP1-1 Agonists

Glucagon-like peptide-1(GLP-1)promotes insulin secretion,inhibits glucagon secretion,and repairs pancreatic islet cell function to enhance islet cell proliferation and regeneration.Furthermore,it includes a mechanism for weight loss and angiocarpy protection.This study covers the comparison of GLP-1 agonists with DPP-4 inhibitors and GLT-2 inhibitors,the mechanism of GLP-1 agonists,and its research possibilities based on a summary of current clinical tests of GLP-1 receptor agonists.

Clinical Effect of Laser Treatment Combined with Compound Xueshuantong Capsule in the Treatment of Diabetic Retinopathy

Objective:To determine the clinical value of compound Xueshuantong capsule in the treatment of diabetic retinopathy on the basis of laser treatment.Methods:Data were collected from 98 patients with diabetic retinopathy from February 2021 to February 2022.They were divided into two groups by drawing lots.The experimental group was treated with compound Xueshuantong capsule and laser treatment,whereas the control group was treated with laser treatment alone.Results:The absorption of exudation,resolution of retinal edema,and absorption of bleeding took longer in the control group;the incidence of visual acuity recovery to more than 0.5 and the patients’blood glucose levels were better in the experimental group,p<0.05.Conclusion:For patients with diabetic retinopathy,laser treatment combined with compound Xueshuantong capsule can effectively improve the visual function and rehabilitation efficiency of patients with diabetic retinopathy as well as stabilize their blood sugar levels.It has high clinical application value.

Observation on the Curative Effect of Auricular Acupoint Sticking Combined with Acupoint Sticking in the Treatment of Diabetic Constipation

The study was conducted to observe the clinical effect of acupoint and auricular point application on diabetes patients with constipation.Around 104 patients with diabetes and constipation were selected from the Hospital Shaanxi University of Chinese Medicine from February 2021 to February 2022 as the study subjects.They were divided into groups by drawing lots.The experimental group carried out the combined analysis of acupoint and auricular point application based on the treatment methods of the control group.Meanwhile,the control group carried out the traditional treatment,and the evaluation index,including the improvement of constipation and the clinical effective rate data were included in the analysis.This study showed that,the total effective number of patients,times of defecation per week,time of defecation,and interval of defecation in the experimental group were greater,compared to control group(p<0.05).In summary,diabetes patients with constipation,the auricular plaster and acupoint application can effectively improve the constipation symptoms,shorten the defecation time,improve the cure rate of the disease,and ensure the normal defecation cycle in the patients.

Statistical Analysis and Evaluation of Macroeconomic Policies: A Selective Review

In this paper,we highlight some recent developments of a new route to evaluate macroeconomic policy effects,which are investigated under the framework with potential outcomes.First,this paper begins with a brief introduction of the basic model setup in modern econometric analysis of program evaluation.Secondly,primary attention goes to the focus on causal effect estimation of macroeconomic policy with single time series data together with some extensions to multiple time series data.Furthermore,we examine the connection of this new approach to traditional macroeconomic models for policy analysis and evaluation.Finally,we conclude by addressing some possible future research directions in statistics and econometrics.

SURGICAL TREATMENT OF METASTATIC SPINAL TUMOR

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Recent Researches in Repair of Unilateral Cleft Lip Nasal Deformity

The cleft lip nasal deformity accounts for 84% of nasal deformities, which is one of the most common diseases in plastic surgery. The Unilateral cleft lip nasal deformity ,which has a high incidence,had many treatments but not very effective.In this article, we will focus on the repair of unilateral cleft lip nasal deformity, embryology and etiology, anatomy and pathology, classification, preoperative evaluation and repair timing strategies, surgical goals and surgical techniques, postoperative care and effect evaluation . I hope to bring some useful information for clinicians to further guide clinical work.

Clinical Effect of Integrated Traditional Chinese and Western Medicine on Diabetic Peripheral Neuropathy

Objective:Patients with diabetic peripheral neuropathy were treated with integrated traditional Chinese and western medicine,and the final results were observed.Methods:70 patients with such symptoms were randomly divided into two groups.The number of people is the same,and the treatment methods are different.The control group uses western medicine,while the observation group uses traditional Chinese medicine to evaluate the treatment effect.Results:After treatment,the effective rate of the observation group was(P<0.05),indicating that the treatment effect was significantly better.Conclusion:Patients with clinical diabetic peripheral neuropathy treated with routine nutrition and nerve repair,and with Chinese medicine,the effect is more satisfactory,and the effect is positive,so as to promote the optimization of their health.

Could We Use Clinical Benefit to Evaluate the Effects of Chinese Medicine on the Treatment of Cancer?

The patients, who cannot endure the chemotherapy anymore, or internal disease or present drug resistance, normally use CM for improving their physical conditions and inhibiting tumor. CM has got excellent reputation because of the effects. Nonetheless, few clinical articles of CM to treat cancer are published on major international journals up to now.

Prevalence of metabolic syndrome in type 2 diabetic patients: A comparative study using WHO, NCEP ATP III, IDF and Harmonized definitions

To determine the prevalence of metabolic syndrome (MetS) in Malaysian type 2 diabetic patients using WHO, NCEP ATP III, IDF and the new Harmonized definitions, and the concordance between these definitions. This study involved 313 patients diagnosed with type 2 diabetes mellitus (T2DM) at two Malaysian tertiary hospitals. Socio-demographic data were assessed using a pre-tested interviewer-administered structured questionnaire. Anthropometric measurements were carried out according to standard protocols. Clinical and laboratory characteristics were examined. Kappa (k) statistics were used for the agreement between the four MetS definitions. The overall prevalence rates of MetS (95% CI) were 95.8% (93.6-98.1), 96.1% (94.0-98.3), 84.8% (80.8-88.9) and 97.7% (96.1-99.4) according to the WHO, NCEP ATP III, IDF and the Harmonized definitions, respectively. The Kappa statistics demonstrated a slight to substantial agreement between the definitions (k = 0.179-0.875, p k = 0.875, p hest specificity (100%) in identifying MetS. In conclusion, the new Harmonized criteria established the highest prevalence of MetS among the four definitions applied. There was a very good concordance between the WHO and NCEP ATP III criteria. The extremely high prevalence of MetS observed in type 2 diabetic patients indicates an impending pandemic of CVD risk in Malaysia. Aggressive treatment of MetS components is required to reduce cardiovascular risk in T2DM.

《生活饮用水水质处理器卫生安全与功能评价规范》实施效果调查与分析

《生活饮用水水质处理器卫生安全与功能评价规范》(以下简称《规范》)自2001年发布以来已实施20余年,该规范对饮用水水质处理器的市场准入起到重要的作用。2023年国家疾病预防控制局发布了《生活饮用水水质处理器卫生安全与功能评价标准》行业标准的制订计划,为了解《规范》实施过程中存在的问题及对制订卫生行业标准的建议,此研究对来自饮用水处理器生产企业、卫生监督机构、涉水产品检验机构及各级疾病预防控制中心(以下简称各级疾控中心)的133名工作人员开展问卷调查,调查内容包括参与人员的基本信息、对饮用水水质处理器的认知、关于修订《规范》的看法、《规范》的适用范围、卫生安全试验、加标试验、总体性能试验和《规范》的适用性等方面。结果显示:58%的被调查者工作年限在10年以上,具有丰富的专业经验和知识背景;约70%的被调查者对当前生活饮用水水质处理器的卫生安全与功能表现比较满意;约90%的被调查者认为修订《规范》是必须且重要的。对《规范》具体内容的调查发现:《规范》中缺乏具体的操作细则和标准,导致在实际操作中难以统一执行;饮用水处理器生产企业的被调查者主要关注卫生安全性试验,建议修订卫生安全性试验评价指标;涉水产品检验机构以及各级疾控中心的被调查者在检测指标限值的修改方面普遍持认可意见。为推动水质处理器的健康发展,保障公众饮用水安全,应加快《规范》的制订与发布,细化试验的操作要求与细则,完善评价指标与限值要求。

糖尿病并发脓毒症患者应用二甲双胍临床效果分析

目的 研究糖尿病并发脓毒症患者应用二甲双胍的临床治疗效果。方法 选择2020年10月至2023年10月在我院接受治疗的60例糖尿病患者作为研究对象,依据不同治疗方式分成常规组和分析组,常规组采用抗生素控制感染、胰岛素纠正血糖、纠正酸中毒等药物治疗,研究组基于常规治疗联合二甲双胍治疗。对比2组患者病死率、治疗效果、乳酸水平、血清炎性因子、尿素氮(BUN)、血清肌酐(Scr)值等变化。采用SPSS19.0软件包进行统计分析,计数资料组间比较运用χ^(2)检验,计量资料组间比较运用t检验。结果研究组治疗病死率(20.0%)显著优于常规组(46.7%),差异有统计学意义(χ^(2)=4.800,P<0.05);研究组治疗有效率达(96.7%)高于常规组(66.7%),差异有统计学意义(χ^(2)=13.293,P<0.05);治疗后研究组炎性因子降钙素原(PCT)、白细胞介素(IL)-6、C反应蛋白(CRP)及BUN、Scr值,均低于常规组,差异有统计学意义(P<0.05)。结论二甲双胍可能通过在不同的器官中抑制促炎细胞因子的产生,改善糖尿病并发脓毒症临床症状和脓毒症的肾脏等器官损伤,降低病死率。

达格列净治疗早期糖尿病肾病的临床效果研究

目的研究早期糖尿病肾病患者接受达格列净治疗的临床效果。方法选取2022年4月—2024年3月泰州市第二人民医院收治的76例早期糖尿病肾病患者为研究对象,按照治疗方法不同分为两组,各38例。研究组采用达格列净治疗,对照组采用二甲双胍治疗。比较两组血糖水平、肾功能、临床疗效。结果研究组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。治疗后,研究组血尿素氮、血肌酐、尿微量白蛋白水平均低于对照组,差异有统计学意义(P均<0.05)。治疗后,研究组空腹血糖、餐后2 h血糖、糖化血红蛋白水平均低于对照组,差异有统计学意义(P均<0.05)。结论达格列净用于早期糖尿病肾病治疗中,可修复患者受损的肾功能,有效控制血糖,临床疗效较好。

阿柏西普联合雷珠单抗治疗效果欠佳的糖尿病黄斑水肿的疗效分析

目的探讨阿柏西普联合雷珠单抗治疗效果欠佳的糖尿病黄斑水肿患者的效果。方法回顾性选取2021年9月—2022年9月广州医科大学第六附属医院收治的90例糖尿病黄斑水肿患者的临床资料,依据用药方案不同分为两组。对照组(n=45,均为单侧眼病变)用雷珠单抗持续治疗,观察组(n=45,均为单侧眼病变)用雷珠单抗联合阿柏西普治疗。比较两组治疗后的视力、眼压、视网膜厚度、不良反应发生情况。结果观察组在治疗前的视力、黄斑中心厚度、眼压与单一组比较,差异无统计学意义(P均>0.05)。治疗后,观察组的视力较对照组明显提高,观察组的黄斑中心凹厚度和眼压对比对照组明显降低,差异有统计学意义(P均<0.05)。两组不良反应发生情况对比,差异无统计学意义(P>0.05)。结论对于雷珠单抗治疗效果欠佳的糖尿病黄斑水肿患者,雷珠单抗联合阿柏西普治疗对患者的视力提高作用明显,对视网膜结构的改善成效突出,治疗安全有效。

水资源污染综合治理措施及其防治效果评估研究

长期的水污染会破坏水环境,造成生态系统的破坏和失衡,影响人类的生产和生活。为此,研究水资源污染综合治理措施并评估防治效果。在分析了水资源污染物的4种主要类型后,从工业生产、市政管理以及工程保障3方面提出相应的治理措施,并使用模糊综合评价法对治理后的效果评价,将评价结果分为5个等级,利用加权平均原则对评价结果定量计算。将所提治理措施应用在某市生态公园调节塘内,经一段时间后检验该塘水质有了明显改善,防治效果评估结果为优秀,证明所提方法在水资源污染治理方面具有可行性。

德谷胰岛素联合西格列汀二甲双胍治疗难治性2型糖尿病的临床研究

目的探讨德谷胰岛素联合西格列汀二甲双胍治疗难治性2型糖尿病患者的临床效果。方法选取2021年5月至2023年3月我院收治的84例难治性2型糖尿病住院患者,随机分为试验组(42例)和参照组(42例)。参照组采用西格列汀二甲双胍治疗,试验组采用德谷胰岛素联合西格列汀二甲双胍治疗。比较两组的血糖水平、低血糖发生情况。结果治疗12周后,两组空腹血糖(FPG)、餐后2h血糖(2hPBG)和糖化血红蛋白(HbA1c)水平降低,且试验组FPG、2hPBG、HbA1c水平低于参照组(P<0.05)。试验组治疗期间低血糖发生率为11.90%,与参照组的9.52%无统计学差异(P>0.05)。结论德谷胰岛素联合西格列汀二甲双胍治疗难治性2型糖尿病患者的控糖效果更佳,且未明显增加低血糖发生风险,安全性较高,值得临床推广。

长效胰岛素联合口服降糖药治疗2型糖尿病的疗效

目的 分析2型糖尿病(T2DM)采取长效胰岛素+口服降糖药治疗的效果。方法 96例T2DM患者,随机分为观察组和对照组,每组48例。对照组给予口服降糖药治疗,观察组给予长效胰岛素+口服降糖药治疗。比较两组患者治疗前后的血糖[糖化血红蛋白(HbA1c)、餐后2 h血糖(2 h PG)、空腹血糖(FPG)]水平、生活质量(总体健康、精力、社会功能、心理健康、躯体疼痛、躯体角色功能、情绪角色功能、躯体健康)评分以及不良反应发生情况(体重增加、低血糖)、治疗效果。结果 治疗后,观察组患者HbA1c(6.20±0.91)%、2 h PG(8.63±1.37)mmol/L、FPG(5.83±0.72)mmol/L均低于对照组的(8.34±1.15)%、(9.56±1.60)mmol/L、(7.91±1.31)mmol/L,差异具有统计学意义(P<0.05)。观察组不良反应发生率2.08%(1/48)低于对照组的14.58%(7/48),差异具有统计学意义(χ^(2)=4.909,P<0.05)。治疗后,观察组患者总体健康评分(63.25±4.48)分、精力评分(74.25±4.54)分、社会功能评分(83.67±3.91)分、心理健康评分(81.48±4.25)分、躯体疼痛评分(74.48±6.38)分、躯体角色功能评分(73.54±4.18)分、情绪角色功能评分(84.54±3.67)分、躯体健康评分(71.37±4.28)分;对照组患者总体健康评分(54.54±3.25)分、精力评分(61.22±4.01)分、社会功能评分(76.32±2.75)分、心理健康评分(61.24±3.75)分、躯体疼痛评分(66.58±4.70)分、躯体角色功能评分(61.24±4.42)分、情绪角色功能评分(73.05±2.50)分、躯体健康评分(52.31±2.76)分。观察组患者总体健康、精力、社会功能、心理健康、躯体疼痛、躯体角色功能、情绪角色功能、躯体健康评分均高于对照组,差异有统计学意义(P<0.05)。观察组治疗总有效率95.83%高于对照组的79.17%,差异具有统计学意义(P<0.05)。结论 长效胰岛素联合口服降糖药物对T2DM治疗可有效改善血糖水平,降低不良反应发生率,提升疗效。