Diagnosis is of great importance to wireless sensor networks due to the nature of error prone sensor nodes and unreliable wireless links. The state-of-the-art diagnostic tools focus on certain types of faults, and the...Diagnosis is of great importance to wireless sensor networks due to the nature of error prone sensor nodes and unreliable wireless links. The state-of-the-art diagnostic tools focus on certain types of faults, and their performances are highly correlated with the networks they work with. The network administrators feel difficult in measuring the effectiveness of their diagnosis approaches and choosing appropriate tools so as to meet the reliability demand. In this work, we introduce the D-vector to characterize the property of a diagnosis approach. The D-vector has five dimensions, namely the degree of coupling, the granularity, the overhead, the tool reliability and the network reliability, quantifying and evaluating the effectiveness of current diagnostic tools in certain applications. We employ a skyline query algorithm to find out the most effective diagnosis approaches, i.e., skyline points（SPs）, from five dimensions of all potential D-vectors. The selected skyline D-vector points can further guide the design of various diagnosis approaches. In our trace-driven simulations, we design and select tailored diagnostic tools for GreenOrbs, achieving high performance with relatively low overhead.展开更多
To establish a quick and applicable diagnostic method has been a major target in immunological research on malaria. Of all approaches studied, circulating antigen (CAg) detection seems to be the most promising. Scient...To establish a quick and applicable diagnostic method has been a major target in immunological research on malaria. Of all approaches studied, circulating antigen (CAg) detection seems to be the most promising. Scientists have encountered tough difficulties in the analysis and purification of malaria parasite antigen because of its high complexity. Studies showed that plasmadium falciparum (P.f) lactate dehydrogenase (pLDH), as a specific CAg of malaria parasite. is apparently different from that of human erythrocytes (rLDH) both in their physical and biochemical characteristics. and is very easy to be identifed. Consequently, pLDH detection has a great potential to be developed into a method for assessing parasitemia. This paper reviewed the methods for the purification. separation, identification of pLDH and the prospect of its clinical applications as an ideal detector of the presence of malaria parasite in order to speed up this research.展开更多
基金supported by the National Natural Science Foundation of China under Grant Nos.61190110,61325013,61103187,61170213,61228202,61170216,and 61422207the National Basic Research 973 Program of China under Grant No.2014CB347800+2 种基金the Natural Science Foundation of USA under Grant Nos.CNS-0832120,CNS-1035894,ECCS-1247944,and ECCS-1343306the Fundamental Research Funds for the Central Universities of China under Project No.2012jdgz02(Xi’an Jiaotong University)the Research Fund for the Doctoral Program of Higher Education of China under Project No.20130201120016
文摘Diagnosis is of great importance to wireless sensor networks due to the nature of error prone sensor nodes and unreliable wireless links. The state-of-the-art diagnostic tools focus on certain types of faults, and their performances are highly correlated with the networks they work with. The network administrators feel difficult in measuring the effectiveness of their diagnosis approaches and choosing appropriate tools so as to meet the reliability demand. In this work, we introduce the D-vector to characterize the property of a diagnosis approach. The D-vector has five dimensions, namely the degree of coupling, the granularity, the overhead, the tool reliability and the network reliability, quantifying and evaluating the effectiveness of current diagnostic tools in certain applications. We employ a skyline query algorithm to find out the most effective diagnosis approaches, i.e., skyline points（SPs）, from five dimensions of all potential D-vectors. The selected skyline D-vector points can further guide the design of various diagnosis approaches. In our trace-driven simulations, we design and select tailored diagnostic tools for GreenOrbs, achieving high performance with relatively low overhead.
文摘To establish a quick and applicable diagnostic method has been a major target in immunological research on malaria. Of all approaches studied, circulating antigen (CAg) detection seems to be the most promising. Scientists have encountered tough difficulties in the analysis and purification of malaria parasite antigen because of its high complexity. Studies showed that plasmadium falciparum (P.f) lactate dehydrogenase (pLDH), as a specific CAg of malaria parasite. is apparently different from that of human erythrocytes (rLDH) both in their physical and biochemical characteristics. and is very easy to be identifed. Consequently, pLDH detection has a great potential to be developed into a method for assessing parasitemia. This paper reviewed the methods for the purification. separation, identification of pLDH and the prospect of its clinical applications as an ideal detector of the presence of malaria parasite in order to speed up this research.
