The Fifteenth Natlonal Con-gress,a very important andgrand trans—century meeting inthe history Of CCP,was inaugu-rated in Beijing on September 12,1997. Guangdong Customs have sentrepresentatives to attend the Party’...The Fifteenth Natlonal Con-gress,a very important andgrand trans—century meeting inthe history Of CCP,was inaugu-rated in Beijing on September 12,1997. Guangdong Customs have sentrepresentatives to attend the Party’sCongress for the first time in his-tory.Among the two representa-tives is Liu Wenjie,director ofGuangdong CUStoms Branch Of-fice and of Guangzhou Customs.On September 23 after conclusionof the Coilgress,this reporter inte-Viewed directory Liu Wenjie in展开更多
Background: Globally, PRAKI is among the leading causes of death in pregnant women. The prevalence, causes and outcome of this condition vary among countries due to differences in environmental, socioeconomic, and hea...Background: Globally, PRAKI is among the leading causes of death in pregnant women. The prevalence, causes and outcome of this condition vary among countries due to differences in environmental, socioeconomic, and health delivery systems. The common causes that have been reported in several studies are PIH, Haemorrhages and Sepsis while the outcomes may be either complete renal recovery, progression to CKD and hence dialysis dependency or death. This study aimed at determining clinical presentation and treatment outcomes of Pregnancy-Related Acute Kidney Injury in Pregnant women admitted at the Benjamin Mkapa Hospital, Dodoma, Tanzania. Results: Out of 4007 pregnant women who were admitted to the maternity ward 51 pregnant women were found to have PRAKI. Of those with PRAKI, 74.5% were between 21 to 25 years. The leading causes of PRAKI were PPH 12 (23.53%), Eclampsia 12 (23.53%), and pre-eclampsia 12 (23.5%). Hemodialysis therapy was provided to 22 (43.1%) patients, 15 (29.4%) individuals recovered spontaneously with medical management and 14 (27.5%) missed haemodialysis therapy due to various reasons. The mortality due to PRAKI was 17 (33.3%). Conclusion and Recommendation: Pre-eclampsia/eclampsia and post-partum haemorrhage were found to be the main causes of PRAKI. The mortality related to PRAKI is high and Hemodialysis therapy is vital help to prevent deaths for pregnant women with PRAKI. Pregnant women who develop acute kidney injury should be followed closely and a nephrologist should be consulted early. Early referral should be done by the lower level facilities for all at-risk pregnant women to a specialized multidisciplinary health facility.展开更多
Based on the empirical investigation of presentation in college English classes for junior non-English majors in science and engineering universities,the author explains her own thinking on how to improve presentation...Based on the empirical investigation of presentation in college English classes for junior non-English majors in science and engineering universities,the author explains her own thinking on how to improve presentation teaching from four aspects:setting teaching objectives,selecting teaching contents,using teaching methods,and evaluating and implementing methods.展开更多
The link between chronic inflammation and colorectal cancer has been well established. The events proceeding along tumorigenesis are complicated and involve cells activated at the cancer microenvironment, tumor infilt...The link between chronic inflammation and colorectal cancer has been well established. The events proceeding along tumorigenesis are complicated and involve cells activated at the cancer microenvironment, tumor infiltrating polymorphonuclears, immune cells including lymphocyte subtypes and peripheral blood mononuclear cells(PBMC), as well as tumor-associated macrophages. The immune cells generate inflammatory cytokines, several of them playing a crucial role in tumorigenesis. Additional factors, such as gene expression regulated by cytokines, assembling of tumor growth- and transforming factors, accelerated angiogenesis, delayed apoptosis, contribute all to initiation, development and migration of tumor cells. Oxygen radical species originating from the inflammatory area promote cell mutation and cancer proliferation. Tumor cells may over-express pro-inflammatory mediators that in turn activate immune cells for inflammatory cytokines production. Consequently, an immune dialogue emerges between immune and cancer cells orchestrated through a number of activated molecular pathways. Cytokines, encompassing migration inhibitory factor, transforming growth factor beta 1, tumor necrosisfactor-α, Interleukin(IL)-6, IL-10, IL-12, IL-17, IL-23 have been reported to be involved in human cancer development. Some cytokines, namely IL-5, IL-6, IL-10, IL-22 and growth factors promote tumor development and metastasis, and inhibit apoptosis via activation of signal transducer activator transcription-3 transcription factor. Colon cancer environment comprises mesenchymal, endothelial and immune cells. Assessment of the interaction between components in the tumor environment and malignant cells requires a reconsideration of a few topics elucidating the role of chronic inflammation in carcinogenesis, the function of the immune cells expressed by inflammatory cytokine production, the immunomodulation of cancer cells and the existence of a cross-talk between immune and malignant cells leading to a balance in cytokine production. It is conceivable that the prevalence of anti-inflammatory cytokine production by PBMC in the affected colonic mucosa will contribute to the delay, or even to halt down malignant expansion. Targeting the interplay between immune and cancer cells by mediators capable to alter cytokine secretion toward increased anti-inflammatory cytokine release by PBMC and tumor associated macrophages, may serve as an additional strategy for treatment of malignant diseases. This review will focus on the inflammatory events preceding tumorigenesis in general, and on a number of modulators capable to affect colon cancer cell-induced production of inflammatory cytokines by PBMC through alteration of the immune crosstalk between PBMC and cancer cells.展开更多
In this article, the distribution of cultivated land, the changes ofcultivated land productivity, and regional differentiation of the Change forpresent productivity in the Farming-Pastoral Zone, Inner Mongolia aredis...In this article, the distribution of cultivated land, the changes ofcultivated land productivity, and regional differentiation of the Change forpresent productivity in the Farming-Pastoral Zone, Inner Mongolia arediscussed. Then, the close relationship between dynamic characterlsticsdivision and atmospheric circulation systems is revealed. Finally, based ondynamic characteristics, four regions are divided, including thenortheastem area, the eastern area, the western area, and the middle area.展开更多
One of the greatest unmet needs in the treatment of Parkinson’s disease(PD)is a disease-modifying therapy,which can halt the ongoing degeneration of dopaminergic neurons that is characteristic of this disorder.Curr...One of the greatest unmet needs in the treatment of Parkinson’s disease(PD)is a disease-modifying therapy,which can halt the ongoing degeneration of dopaminergic neurons that is characteristic of this disorder.Current therapies focus on managing symptoms,rather than on addressing their cause.Promising candidates for disease-modifying therapies are the dopaminergic neurotrophic factors(NTFs).展开更多
Concept-based instruction(C-BI)has proven to be effective in improving students’command of grammar items used out of context by offering the students revision lessons,but its effect in teaching newly-introduced gramm...Concept-based instruction(C-BI)has proven to be effective in improving students’command of grammar items used out of context by offering the students revision lessons,but its effect in teaching newly-introduced grammar items in a complex context of a specific genre remains unclear.To probe C-BI’s effect on students’use of the past simple and present perfect tenses out of context and in the context of a narrative by its description of the grammar concept in its materialization,that is,the Schemas of a Complete Orienting Basis of an Action(SCOBAs),we taught the two tenses to 40 eighth-graders in a Chinese middle school in our three-week teaching experiment.The qualitative and quantitative analysis of the results shows that i)in both out-ofcontext use and in-context use,accuracy of using the target tenses is higher after C-BI intervention;ii)by improving their conceptual knowledge through C-BI,the students are helped to pin down reference time and are hence more certain in using the target tenses.Moreover,they are encouraged to use the newly-introduced tenses in the complex context of the narrative genre;iii)both in simple contexts or complex contexts,the SCOBAs are effective in helping students navigate the learning task and determine their intended meaning by establishing temporal reference in the context.展开更多
Yeats’ realistic poetry is often imprinted with the mark of its era. By means of the poetic language, Yeats expressed his profound reflection on the historic events of the time. In so doing, a dialogue has comes into...Yeats’ realistic poetry is often imprinted with the mark of its era. By means of the poetic language, Yeats expressed his profound reflection on the historic events of the time. In so doing, a dialogue has comes into existence between literature and history. This paper attempts to consider in detail how the dialogue between literature and history operates in Yeats’ realistic poem “Easter, 1916,” as a case study, under the scrutiny of the new historicist approach. Through the textual analysis of this poetic work, this paper discusses the dialogic relationship of the poem and history by elaborating on how this poetic work becomes historicized and how this historic event becomes textualized. Within this dialogue, the reciprocal relation of this poem and the contemporary society is brought under further examination. This paper argues that this poem harbors subversive force which can be articulated by the poetic text in this dialogue between literature and history. However, this subversive force will be eventually contained by the British power structure that has pervaded and dominated the Irish society. By the uprising and revolution of the Irish people, Ireland would attain to the goal of political de-Anglicization by becoming a sovereign state and with the advent of this political independence Irish literature could also achieve an independent status. However, this paper concludes that Yeats has realized the suppressed beauty of this independence because Irish literature would still have to be composed in the English language which, however, remains to be the product of the British power structure.展开更多
On May 15, the Conference on Dialogue of Asian Civilizations (CDAC) opened in Beijing. Chinese President Xi Jinping delivered a keynote speech at the opening ceremony.“To meet our common challenges and create a bette...On May 15, the Conference on Dialogue of Asian Civilizations (CDAC) opened in Beijing. Chinese President Xi Jinping delivered a keynote speech at the opening ceremony.“To meet our common challenges and create a better future for all, we look to culture and civilization to play their role, which is as important as the role played by the economy.展开更多
Prevention of blindness is the most important aim of ophthalmology. Prevention of blindness is related to many factors. It is related to many factors, such as science and technology, economy and social behavior. There...Prevention of blindness is the most important aim of ophthalmology. Prevention of blindness is related to many factors. It is related to many factors, such as science and technology, economy and social behavior. There are worldwide activities by WHO, NGOs and other functions to promote the prevention of blindness in the world. More than 90% of blind population lives in developing world. Cataract is the top causes of blindness which is curable. Onchocerciasis is an endemic disease in west Africa and cent...展开更多
[Objective] This study aimed to investigate the changes of the transcriptional levels of molecules associated with endogenous antigen processing and presenta- tion in porcine skin-derived dendritic cells infected with...[Objective] This study aimed to investigate the changes of the transcriptional levels of molecules associated with endogenous antigen processing and presenta- tion in porcine skin-derived dendritic cells infected with PCV2 in vivo. [Method] Healthy 40-day-old Landrace piglets were infected with porcine circovirus type 2 (PCV2) and euthanized on the 34, 7rd, 14th, 21st and 35th d post inoculation (DPI). The porcine skin-derived dendritic cells (DCs) were collected to analyze the transcrip- tional levels of molecules (LMP7, UBP, MHC-I, calreticulin) associated with endogenous antigen processing and presentation by using real-time fluorescent quantitative PCR (real-time FQ-PCR). [Result] The results showed that the level of LMP7 mR- NAs was reduced significantly on the 3DPI (P〈0.05); the level of UBP mRNAs was consistently up-regulated, which increased significantly on the 21DPI and 35DPI (P〈 0.05); the level of MHC-I mRNAs was significantly down-regulated on the 7DPI (P〈 0.05); the level of calreticulin mRNAs was up-regulated slightly without significant dif- ference. [Conclusion] PCV2 can inhibit the endogenous antigen processing and presentation ability of porcine skin-derived DCs at early stages of infection.展开更多
The past has had a minor consideration in geographic studies the transformation of rural areas,usually dominated by socioeconomic analysis.Incorporating the old and in many cases,the materialities of the past through ...The past has had a minor consideration in geographic studies the transformation of rural areas,usually dominated by socioeconomic analysis.Incorporating the old and in many cases,the materialities of the past through a reconsideration of heritage to the future of rural space requires an adequate conceptualization and reconsideration of rural materialities and especially of popular housing.In this way,it is intended to decentralize the human and functionalist point of view to give a life of their own to rural cultural and natural materialities in the context of more-than-human-geographies.The renewed study of heritage and the historical past acquires a notable value in the present and future of rural areas through:(1)the interpretation of dissymmetrical realities where the old confronts new activities;(2)for adequate and realistic management of rural heritage and the processes of selective recovery of heritage in certain historical places.展开更多
Both Marxism and nationalism are among the most far-reaching thoughts in modern times.On dealing the ideological collision between Marxism and nationalism, "Difficult Dialogue" universally exists in the acad...Both Marxism and nationalism are among the most far-reaching thoughts in modern times.On dealing the ideological collision between Marxism and nationalism, "Difficult Dialogue" universally exists in the academic circle.Many scholars evaded,ridiculed or even negated classic Marxist writers' explications on nationalism.Though basically,classic Marxist writers criticize nationalism,it doesn' t mean that Marxism and nationalism inevitably oppose to each other.It is highly necessary to analyze the causes of the "difficult dialogue between Marxism and nationalism" and re-thinking classic Marxist writers' explications on nationalism.展开更多
TOURISTS traveling to Beijing always have the Great Wall,Tiananmen Square and the Forbidden City on their must-see list.But what if you have already seen the sights?Then it’s time to explore the ancient capital’s hu...TOURISTS traveling to Beijing always have the Great Wall,Tiananmen Square and the Forbidden City on their must-see list.But what if you have already seen the sights?Then it’s time to explore the ancient capital’s hutongs.Featured this issue is Nanluoguxiang Alley,one of downtown Beijing’s best preserved hutongs.With its grey-walled courtyard homes,it offers a real taste of traditional city life. Located several kilometers north of the Forbidden City and east of Houhai Lake, Nanluoguxiang Alley is a 786-meter-long and 8-meter-wide lane.It stretches northsouth from Gulou East Street to Di’anmen East Street.展开更多
正The Understanding and Cooperation Dialogue, Sponsored by the Chinese Association for International Understanding (CAFIU) and the China Foundation for Peace and Development (CFPD), and Co-organized by the Chinese Peo...正The Understanding and Cooperation Dialogue, Sponsored by the Chinese Association for International Understanding (CAFIU) and the China Foundation for Peace and Development (CFPD), and Co-organized by the Chinese People' s Association for Peace and展开更多
Although there are appropriate stipulations for the chattel guarantees in the law of China, this guarantee system could not adapt to the request of economy's development because of the following reasons: the scope...Although there are appropriate stipulations for the chattel guarantees in the law of China, this guarantee system could not adapt to the request of economy's development because of the following reasons: the scope of chattel guarantees is narrow according to relevant stipulations; the transaction cost of the chattel is high; mortgage registration of chattel is in a mess; lack of efficiently executive guarantee system, etc. To counter the problems existing in the present Chinese chattel guarantee system, in this article, the author proposed some corresponding suggestions and countermeasures, hoping to perfect the chattel guarantee system in China.展开更多
The"Decoding Zhonghua"International Conference on Dialogue among Civilisations,hosted by China International Public Relations Association,China Ethnic News and Academy of Contemporary China and World Studies...The"Decoding Zhonghua"International Conference on Dialogue among Civilisations,hosted by China International Public Relations Association,China Ethnic News and Academy of Contemporary China and World Studies was held in Beijing on January 17th.With the theme"Pursing Harmonious Coexistence of Civilisations through Dialogue".展开更多
Angiotensin Receptor Blockers (ARB) are used as an alternative of Angiotensin Converting Enzyme Inhibitors (ACEI) in patients where ACEIs cannot be used because of their known adverse effects, cough and angioedema. Th...Angiotensin Receptor Blockers (ARB) are used as an alternative of Angiotensin Converting Enzyme Inhibitors (ACEI) in patients where ACEIs cannot be used because of their known adverse effects, cough and angioedema. Thus ARB induced angioedema is considered to be a rare phenomenon and it is continued to be used as an alternatives of ACEIs. In this case report, we reported a case of 78-year-old gentleman who presented to emergency department with losartan, an ARB induced angioedema, who did not have history of any previous use of ACEIs. He was given steroids and antihistamine as a treatment. His angioedema resolved rapidly and he was discharged after six hours of emergency department (ED) observation with stable hemodynamically. We, the authors by reporting this case, wants to make clinicians aware ARB, however rarely, can cause angioedema, which can be life threatening if clinicians are not aware of it and diagnose and stop the offending drug promptly and treat it early.展开更多
Rural electrification remains a critical challenge in achieving equitable access to electricity, a cornerstone for poverty alleviation, economic growth, and improved living standards. Capacitor Coupled Substations (CC...Rural electrification remains a critical challenge in achieving equitable access to electricity, a cornerstone for poverty alleviation, economic growth, and improved living standards. Capacitor Coupled Substations (CCS) offer a promising solution for delivering cost-effective electricity to these underserved areas. However, the integration of multiple CCS units along a transmission network introduces complex interactions that can significantly impact voltage, current, and power flow. This study presents a detailed mathematical model to analyze the effects of varying distances and configurations of multiple CCS units on a transmission network, with a focus on voltage stability, power quality, and reactive power fluctuations. Furthermore, the research addresses the phenomenon of ferroresonance, a critical issue in networks with multiple CCS units, by developing and validating suppression strategies to ensure stable operation. Through simulation and practical testing, the study provides insights into optimizing CCS deployment, ultimately contributing to more reliable and efficient rural electrification solutions.展开更多
文摘The Fifteenth Natlonal Con-gress,a very important andgrand trans—century meeting inthe history Of CCP,was inaugu-rated in Beijing on September 12,1997. Guangdong Customs have sentrepresentatives to attend the Party’sCongress for the first time in his-tory.Among the two representa-tives is Liu Wenjie,director ofGuangdong CUStoms Branch Of-fice and of Guangzhou Customs.On September 23 after conclusionof the Coilgress,this reporter inte-Viewed directory Liu Wenjie in
文摘Background: Globally, PRAKI is among the leading causes of death in pregnant women. The prevalence, causes and outcome of this condition vary among countries due to differences in environmental, socioeconomic, and health delivery systems. The common causes that have been reported in several studies are PIH, Haemorrhages and Sepsis while the outcomes may be either complete renal recovery, progression to CKD and hence dialysis dependency or death. This study aimed at determining clinical presentation and treatment outcomes of Pregnancy-Related Acute Kidney Injury in Pregnant women admitted at the Benjamin Mkapa Hospital, Dodoma, Tanzania. Results: Out of 4007 pregnant women who were admitted to the maternity ward 51 pregnant women were found to have PRAKI. Of those with PRAKI, 74.5% were between 21 to 25 years. The leading causes of PRAKI were PPH 12 (23.53%), Eclampsia 12 (23.53%), and pre-eclampsia 12 (23.5%). Hemodialysis therapy was provided to 22 (43.1%) patients, 15 (29.4%) individuals recovered spontaneously with medical management and 14 (27.5%) missed haemodialysis therapy due to various reasons. The mortality due to PRAKI was 17 (33.3%). Conclusion and Recommendation: Pre-eclampsia/eclampsia and post-partum haemorrhage were found to be the main causes of PRAKI. The mortality related to PRAKI is high and Hemodialysis therapy is vital help to prevent deaths for pregnant women with PRAKI. Pregnant women who develop acute kidney injury should be followed closely and a nephrologist should be consulted early. Early referral should be done by the lower level facilities for all at-risk pregnant women to a specialized multidisciplinary health facility.
文摘Based on the empirical investigation of presentation in college English classes for junior non-English majors in science and engineering universities,the author explains her own thinking on how to improve presentation teaching from four aspects:setting teaching objectives,selecting teaching contents,using teaching methods,and evaluating and implementing methods.
文摘The link between chronic inflammation and colorectal cancer has been well established. The events proceeding along tumorigenesis are complicated and involve cells activated at the cancer microenvironment, tumor infiltrating polymorphonuclears, immune cells including lymphocyte subtypes and peripheral blood mononuclear cells(PBMC), as well as tumor-associated macrophages. The immune cells generate inflammatory cytokines, several of them playing a crucial role in tumorigenesis. Additional factors, such as gene expression regulated by cytokines, assembling of tumor growth- and transforming factors, accelerated angiogenesis, delayed apoptosis, contribute all to initiation, development and migration of tumor cells. Oxygen radical species originating from the inflammatory area promote cell mutation and cancer proliferation. Tumor cells may over-express pro-inflammatory mediators that in turn activate immune cells for inflammatory cytokines production. Consequently, an immune dialogue emerges between immune and cancer cells orchestrated through a number of activated molecular pathways. Cytokines, encompassing migration inhibitory factor, transforming growth factor beta 1, tumor necrosisfactor-α, Interleukin(IL)-6, IL-10, IL-12, IL-17, IL-23 have been reported to be involved in human cancer development. Some cytokines, namely IL-5, IL-6, IL-10, IL-22 and growth factors promote tumor development and metastasis, and inhibit apoptosis via activation of signal transducer activator transcription-3 transcription factor. Colon cancer environment comprises mesenchymal, endothelial and immune cells. Assessment of the interaction between components in the tumor environment and malignant cells requires a reconsideration of a few topics elucidating the role of chronic inflammation in carcinogenesis, the function of the immune cells expressed by inflammatory cytokine production, the immunomodulation of cancer cells and the existence of a cross-talk between immune and malignant cells leading to a balance in cytokine production. It is conceivable that the prevalence of anti-inflammatory cytokine production by PBMC in the affected colonic mucosa will contribute to the delay, or even to halt down malignant expansion. Targeting the interplay between immune and cancer cells by mediators capable to alter cytokine secretion toward increased anti-inflammatory cytokine release by PBMC and tumor associated macrophages, may serve as an additional strategy for treatment of malignant diseases. This review will focus on the inflammatory events preceding tumorigenesis in general, and on a number of modulators capable to affect colon cancer cell-induced production of inflammatory cytokines by PBMC through alteration of the immune crosstalk between PBMC and cancer cells.
文摘In this article, the distribution of cultivated land, the changes ofcultivated land productivity, and regional differentiation of the Change forpresent productivity in the Farming-Pastoral Zone, Inner Mongolia arediscussed. Then, the close relationship between dynamic characterlsticsdivision and atmospheric circulation systems is revealed. Finally, based ondynamic characteristics, four regions are divided, including thenortheastem area, the eastern area, the western area, and the middle area.
文摘One of the greatest unmet needs in the treatment of Parkinson’s disease(PD)is a disease-modifying therapy,which can halt the ongoing degeneration of dopaminergic neurons that is characteristic of this disorder.Current therapies focus on managing symptoms,rather than on addressing their cause.Promising candidates for disease-modifying therapies are the dopaminergic neurotrophic factors(NTFs).
文摘Concept-based instruction(C-BI)has proven to be effective in improving students’command of grammar items used out of context by offering the students revision lessons,but its effect in teaching newly-introduced grammar items in a complex context of a specific genre remains unclear.To probe C-BI’s effect on students’use of the past simple and present perfect tenses out of context and in the context of a narrative by its description of the grammar concept in its materialization,that is,the Schemas of a Complete Orienting Basis of an Action(SCOBAs),we taught the two tenses to 40 eighth-graders in a Chinese middle school in our three-week teaching experiment.The qualitative and quantitative analysis of the results shows that i)in both out-ofcontext use and in-context use,accuracy of using the target tenses is higher after C-BI intervention;ii)by improving their conceptual knowledge through C-BI,the students are helped to pin down reference time and are hence more certain in using the target tenses.Moreover,they are encouraged to use the newly-introduced tenses in the complex context of the narrative genre;iii)both in simple contexts or complex contexts,the SCOBAs are effective in helping students navigate the learning task and determine their intended meaning by establishing temporal reference in the context.
文摘Yeats’ realistic poetry is often imprinted with the mark of its era. By means of the poetic language, Yeats expressed his profound reflection on the historic events of the time. In so doing, a dialogue has comes into existence between literature and history. This paper attempts to consider in detail how the dialogue between literature and history operates in Yeats’ realistic poem “Easter, 1916,” as a case study, under the scrutiny of the new historicist approach. Through the textual analysis of this poetic work, this paper discusses the dialogic relationship of the poem and history by elaborating on how this poetic work becomes historicized and how this historic event becomes textualized. Within this dialogue, the reciprocal relation of this poem and the contemporary society is brought under further examination. This paper argues that this poem harbors subversive force which can be articulated by the poetic text in this dialogue between literature and history. However, this subversive force will be eventually contained by the British power structure that has pervaded and dominated the Irish society. By the uprising and revolution of the Irish people, Ireland would attain to the goal of political de-Anglicization by becoming a sovereign state and with the advent of this political independence Irish literature could also achieve an independent status. However, this paper concludes that Yeats has realized the suppressed beauty of this independence because Irish literature would still have to be composed in the English language which, however, remains to be the product of the British power structure.
文摘On May 15, the Conference on Dialogue of Asian Civilizations (CDAC) opened in Beijing. Chinese President Xi Jinping delivered a keynote speech at the opening ceremony.“To meet our common challenges and create a better future for all, we look to culture and civilization to play their role, which is as important as the role played by the economy.
文摘Prevention of blindness is the most important aim of ophthalmology. Prevention of blindness is related to many factors. It is related to many factors, such as science and technology, economy and social behavior. There are worldwide activities by WHO, NGOs and other functions to promote the prevention of blindness in the world. More than 90% of blind population lives in developing world. Cataract is the top causes of blindness which is curable. Onchocerciasis is an endemic disease in west Africa and cent...
基金Supported by Natural Science Foundation of Beijing "Effect of porcine skin-derived dendritic cells on PCV infection" (6062006)Beijing Organization Department Project"Influence of PCV infection on bone marrow cell differentiation" (20061D0502100282)~~
文摘[Objective] This study aimed to investigate the changes of the transcriptional levels of molecules associated with endogenous antigen processing and presenta- tion in porcine skin-derived dendritic cells infected with PCV2 in vivo. [Method] Healthy 40-day-old Landrace piglets were infected with porcine circovirus type 2 (PCV2) and euthanized on the 34, 7rd, 14th, 21st and 35th d post inoculation (DPI). The porcine skin-derived dendritic cells (DCs) were collected to analyze the transcrip- tional levels of molecules (LMP7, UBP, MHC-I, calreticulin) associated with endogenous antigen processing and presentation by using real-time fluorescent quantitative PCR (real-time FQ-PCR). [Result] The results showed that the level of LMP7 mR- NAs was reduced significantly on the 3DPI (P〈0.05); the level of UBP mRNAs was consistently up-regulated, which increased significantly on the 21DPI and 35DPI (P〈 0.05); the level of MHC-I mRNAs was significantly down-regulated on the 7DPI (P〈 0.05); the level of calreticulin mRNAs was up-regulated slightly without significant dif- ference. [Conclusion] PCV2 can inhibit the endogenous antigen processing and presentation ability of porcine skin-derived DCs at early stages of infection.
文摘The past has had a minor consideration in geographic studies the transformation of rural areas,usually dominated by socioeconomic analysis.Incorporating the old and in many cases,the materialities of the past through a reconsideration of heritage to the future of rural space requires an adequate conceptualization and reconsideration of rural materialities and especially of popular housing.In this way,it is intended to decentralize the human and functionalist point of view to give a life of their own to rural cultural and natural materialities in the context of more-than-human-geographies.The renewed study of heritage and the historical past acquires a notable value in the present and future of rural areas through:(1)the interpretation of dissymmetrical realities where the old confronts new activities;(2)for adequate and realistic management of rural heritage and the processes of selective recovery of heritage in certain historical places.
基金the phased achievement of the national social science fund-Study of Classic Marxist Writers'Explications on Nationalism and Its Contemporary Significance(No:10CMZ002)the national social science fund-Important Literature's Collation and Study of Major CPC Leader'Explications on Nationalism Each Period(No.:13CMZ002)China postdoctoral science foundation-Study of Classic Marxist Writers'Nation-state Theory and Practice(No.:2014M550120)
文摘Both Marxism and nationalism are among the most far-reaching thoughts in modern times.On dealing the ideological collision between Marxism and nationalism, "Difficult Dialogue" universally exists in the academic circle.Many scholars evaded,ridiculed or even negated classic Marxist writers' explications on nationalism.Though basically,classic Marxist writers criticize nationalism,it doesn' t mean that Marxism and nationalism inevitably oppose to each other.It is highly necessary to analyze the causes of the "difficult dialogue between Marxism and nationalism" and re-thinking classic Marxist writers' explications on nationalism.
文摘TOURISTS traveling to Beijing always have the Great Wall,Tiananmen Square and the Forbidden City on their must-see list.But what if you have already seen the sights?Then it’s time to explore the ancient capital’s hutongs.Featured this issue is Nanluoguxiang Alley,one of downtown Beijing’s best preserved hutongs.With its grey-walled courtyard homes,it offers a real taste of traditional city life. Located several kilometers north of the Forbidden City and east of Houhai Lake, Nanluoguxiang Alley is a 786-meter-long and 8-meter-wide lane.It stretches northsouth from Gulou East Street to Di’anmen East Street.
文摘正The Understanding and Cooperation Dialogue, Sponsored by the Chinese Association for International Understanding (CAFIU) and the China Foundation for Peace and Development (CFPD), and Co-organized by the Chinese People' s Association for Peace and
文摘Although there are appropriate stipulations for the chattel guarantees in the law of China, this guarantee system could not adapt to the request of economy's development because of the following reasons: the scope of chattel guarantees is narrow according to relevant stipulations; the transaction cost of the chattel is high; mortgage registration of chattel is in a mess; lack of efficiently executive guarantee system, etc. To counter the problems existing in the present Chinese chattel guarantee system, in this article, the author proposed some corresponding suggestions and countermeasures, hoping to perfect the chattel guarantee system in China.
文摘The"Decoding Zhonghua"International Conference on Dialogue among Civilisations,hosted by China International Public Relations Association,China Ethnic News and Academy of Contemporary China and World Studies was held in Beijing on January 17th.With the theme"Pursing Harmonious Coexistence of Civilisations through Dialogue".
文摘Angiotensin Receptor Blockers (ARB) are used as an alternative of Angiotensin Converting Enzyme Inhibitors (ACEI) in patients where ACEIs cannot be used because of their known adverse effects, cough and angioedema. Thus ARB induced angioedema is considered to be a rare phenomenon and it is continued to be used as an alternatives of ACEIs. In this case report, we reported a case of 78-year-old gentleman who presented to emergency department with losartan, an ARB induced angioedema, who did not have history of any previous use of ACEIs. He was given steroids and antihistamine as a treatment. His angioedema resolved rapidly and he was discharged after six hours of emergency department (ED) observation with stable hemodynamically. We, the authors by reporting this case, wants to make clinicians aware ARB, however rarely, can cause angioedema, which can be life threatening if clinicians are not aware of it and diagnose and stop the offending drug promptly and treat it early.
文摘Rural electrification remains a critical challenge in achieving equitable access to electricity, a cornerstone for poverty alleviation, economic growth, and improved living standards. Capacitor Coupled Substations (CCS) offer a promising solution for delivering cost-effective electricity to these underserved areas. However, the integration of multiple CCS units along a transmission network introduces complex interactions that can significantly impact voltage, current, and power flow. This study presents a detailed mathematical model to analyze the effects of varying distances and configurations of multiple CCS units on a transmission network, with a focus on voltage stability, power quality, and reactive power fluctuations. Furthermore, the research addresses the phenomenon of ferroresonance, a critical issue in networks with multiple CCS units, by developing and validating suppression strategies to ensure stable operation. Through simulation and practical testing, the study provides insights into optimizing CCS deployment, ultimately contributing to more reliable and efficient rural electrification solutions.