Objective: Early detection of LV mechanical abnormalities in patients with cardiac syndrome X (CSX) by speckle tracking echocardiography (STE). Background: Cardiac syndrome X is a triad of angina pectoris, positive st...Objective: Early detection of LV mechanical abnormalities in patients with cardiac syndrome X (CSX) by speckle tracking echocardiography (STE). Background: Cardiac syndrome X is a triad of angina pectoris, positive stress test for myocardial ischemia and angiographically free coronary arteries. Two dimensional speckle tracking?echocardiography (2D-STE) provides a more sensitive method for evaluation of global and segmental LV function than conventional two dimensional echocardiographic parameters. Subjects and Methods: Seventy patients proved to have CSX and 20 healthy control volunteers were included with a mean age of 49.43 ± 5.92 vs. 49.40 ±6.27 years respectively with no difference regarding sex for both patients and controls. Patients with hypertension, diabetes mellitus, valvular heart disease, cardiomyopathies, inflammatory diseases, myocarditis and arrhythmias were excluded. All included individuals were subjected to complete conventional echocardiographic assessment and left ventricular global and segmental mechanical function was assessed using 2D based strain and strain rate (longitudinal, radial and circumferential) imaging. Results: There was no statistically significant difference in LV conventional echo parameters between patients and controls. However, global mean longitudinal strain was significantly lower in patients than controls (-15.05 ± 3.28 vs. -20.22 ± 2.49;p 0.001). For radial and circumferential strain stain, there was no significant changes between patients vs. controls (29.75 ± 18.26 vs. 28.09 ± 15.48;p = 0.74) and (-19.88 ± 8.63 vs. -21.93 ± 5.69;p 0.05) respectively. Conclusion: In spite of normal conventional echo parameters among patients and controls, LV longitudinal strain and strain rate by 2D speckle tracking imaging were lower in the patients denoting subclinical left ventricular mechanical dysfunction in patients with CSX.展开更多
Background： Surgical ventricular restoration （SVR） has been performed to treat left ventricular （LV） aneurysm. However, there is limited analysis of changes in LV shape. This study aimed to evaluate the changes i...Background： Surgical ventricular restoration （SVR） has been performed to treat left ventricular （LV） aneurysm. However, there is limited analysis of changes in LV shape. This study aimed to evaluate the changes in LV shape induced by SVR and the effects of SVR on LV size and function for LV aneurysm. Methods： Between April 2006 and March 2015, 18 patients with dyskinetic （dyskinetic group） and 12 patients with akinetic （akinetic group） postinfarction LV anterior aneurysm receiving SVR with the Dor procedure at Chinese People＇s Liberation Army General Hospital were enrolled in this study. A retrospective analysis was carried out using data from the echocardiography database. LV shape was analyzed by calculating the apical conicity index （ACI）. LV end-diastolic volume index, end-systolic volume index, and ejection fraction （EF） were measured. One-way analysis of variance was used to compare means at different time points within each group. Results： Within one week after SVR, LV shape became more conical in the two groups （ACI decreased from 0.84 ± 0.13 to 0.69 ± 0.11 [t = 5.155, P = 0.000] in dyskinetic group and from 0.73 ± 0.07 to 0.60 ± 0.11 [t = 2.701, P = 0.026] in akinetic group; LV volumes were decreased significantly and became closer to normal values and EF was improved significantly in the two groups）. On follow-up at least one year, LV shape remained unchanged in dyskinetic group （ACI increased from 0.69 ± 0.11 to 0.74 ± 0.12, t = - 1.109, P = 0.294）, but became more spherical in akinetic group （ACI significantly increased from 0.60 ± 0.11 to 0.75 ±0.11, t = -I .880, P = 0.047）; LV volumes remained unchanged in dyskinetic group, but increased significantly in akinetic group and EF remained unchanged in the two groups. Conclusions： SVR could reshape LV to a more conical shape and a more normal size and improve LV function significantly early after the procedure in patients with dyskinetic or akinetic postinfarction LV anterior aneurysm. However, LV tends to be more spherical and enlarged in the akinetic group on at least 1-year follow-up.展开更多
目的分析血清脑钠肽、降钙素原变化与心力衰竭患者纽约心脏病协会(New York Heart Association,NYHA)分级的相关性。方法选取2019年5月—2023年2月云南省玉溪市第二人民医院收治的97例心力衰竭患者为研究对象,所有患者都进行NYHA心功能...目的分析血清脑钠肽、降钙素原变化与心力衰竭患者纽约心脏病协会(New York Heart Association,NYHA)分级的相关性。方法选取2019年5月—2023年2月云南省玉溪市第二人民医院收治的97例心力衰竭患者为研究对象,所有患者都进行NYHA心功能分级后分为3组,心功能Ⅱ级57例(Ⅱ级组),心功能Ⅲ级28例(Ⅲ级组),心功能Ⅳ级12例(Ⅳ级组),检测3组血清脑钠肽、降钙素原含量并进行相关性分析。结果随着NYHA分级的增加,患者的左室射血分数明显降低,左室舒张末期内径明显升高,差异有统计学意义(P均<0.05)。随着NYHA分级的增加,患者的血清脑钠肽、降钙素原含量明显升高,差异有统计学意义(P均<0.05)。Spearman分析显示NYHA分级与血清脑钠肽、降钙素原含量、左室射血分数、左室舒张末期内径存在相关性(r=0.714、0.746、-0.788、0.692,P均<0.05)。结论心力衰竭患者多伴随有血清脑钠肽、降钙素原的高表达,与患者的NYHA分级存在相关性,可作为判断患者病情的重要依据。展开更多
文摘Objective: Early detection of LV mechanical abnormalities in patients with cardiac syndrome X (CSX) by speckle tracking echocardiography (STE). Background: Cardiac syndrome X is a triad of angina pectoris, positive stress test for myocardial ischemia and angiographically free coronary arteries. Two dimensional speckle tracking?echocardiography (2D-STE) provides a more sensitive method for evaluation of global and segmental LV function than conventional two dimensional echocardiographic parameters. Subjects and Methods: Seventy patients proved to have CSX and 20 healthy control volunteers were included with a mean age of 49.43 ± 5.92 vs. 49.40 ±6.27 years respectively with no difference regarding sex for both patients and controls. Patients with hypertension, diabetes mellitus, valvular heart disease, cardiomyopathies, inflammatory diseases, myocarditis and arrhythmias were excluded. All included individuals were subjected to complete conventional echocardiographic assessment and left ventricular global and segmental mechanical function was assessed using 2D based strain and strain rate (longitudinal, radial and circumferential) imaging. Results: There was no statistically significant difference in LV conventional echo parameters between patients and controls. However, global mean longitudinal strain was significantly lower in patients than controls (-15.05 ± 3.28 vs. -20.22 ± 2.49;p 0.001). For radial and circumferential strain stain, there was no significant changes between patients vs. controls (29.75 ± 18.26 vs. 28.09 ± 15.48;p = 0.74) and (-19.88 ± 8.63 vs. -21.93 ± 5.69;p 0.05) respectively. Conclusion: In spite of normal conventional echo parameters among patients and controls, LV longitudinal strain and strain rate by 2D speckle tracking imaging were lower in the patients denoting subclinical left ventricular mechanical dysfunction in patients with CSX.
文摘Background： Surgical ventricular restoration （SVR） has been performed to treat left ventricular （LV） aneurysm. However, there is limited analysis of changes in LV shape. This study aimed to evaluate the changes in LV shape induced by SVR and the effects of SVR on LV size and function for LV aneurysm. Methods： Between April 2006 and March 2015, 18 patients with dyskinetic （dyskinetic group） and 12 patients with akinetic （akinetic group） postinfarction LV anterior aneurysm receiving SVR with the Dor procedure at Chinese People＇s Liberation Army General Hospital were enrolled in this study. A retrospective analysis was carried out using data from the echocardiography database. LV shape was analyzed by calculating the apical conicity index （ACI）. LV end-diastolic volume index, end-systolic volume index, and ejection fraction （EF） were measured. One-way analysis of variance was used to compare means at different time points within each group. Results： Within one week after SVR, LV shape became more conical in the two groups （ACI decreased from 0.84 ± 0.13 to 0.69 ± 0.11 [t = 5.155, P = 0.000] in dyskinetic group and from 0.73 ± 0.07 to 0.60 ± 0.11 [t = 2.701, P = 0.026] in akinetic group; LV volumes were decreased significantly and became closer to normal values and EF was improved significantly in the two groups）. On follow-up at least one year, LV shape remained unchanged in dyskinetic group （ACI increased from 0.69 ± 0.11 to 0.74 ± 0.12, t = - 1.109, P = 0.294）, but became more spherical in akinetic group （ACI significantly increased from 0.60 ± 0.11 to 0.75 ±0.11, t = -I .880, P = 0.047）; LV volumes remained unchanged in dyskinetic group, but increased significantly in akinetic group and EF remained unchanged in the two groups. Conclusions： SVR could reshape LV to a more conical shape and a more normal size and improve LV function significantly early after the procedure in patients with dyskinetic or akinetic postinfarction LV anterior aneurysm. However, LV tends to be more spherical and enlarged in the akinetic group on at least 1-year follow-up.
文摘目的分析血清脑钠肽、降钙素原变化与心力衰竭患者纽约心脏病协会(New York Heart Association,NYHA)分级的相关性。方法选取2019年5月—2023年2月云南省玉溪市第二人民医院收治的97例心力衰竭患者为研究对象,所有患者都进行NYHA心功能分级后分为3组,心功能Ⅱ级57例(Ⅱ级组),心功能Ⅲ级28例(Ⅲ级组),心功能Ⅳ级12例(Ⅳ级组),检测3组血清脑钠肽、降钙素原含量并进行相关性分析。结果随着NYHA分级的增加,患者的左室射血分数明显降低,左室舒张末期内径明显升高,差异有统计学意义(P均<0.05)。随着NYHA分级的增加,患者的血清脑钠肽、降钙素原含量明显升高,差异有统计学意义(P均<0.05)。Spearman分析显示NYHA分级与血清脑钠肽、降钙素原含量、左室射血分数、左室舒张末期内径存在相关性(r=0.714、0.746、-0.788、0.692,P均<0.05)。结论心力衰竭患者多伴随有血清脑钠肽、降钙素原的高表达,与患者的NYHA分级存在相关性,可作为判断患者病情的重要依据。
