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Dietary Surveys Carried out among Diabetic Patients Hospitalized in the Metabolic and Endocrine Diseases Department of the C.H.U-B
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作者 Lewis Raud Miamb Bertin Mikolo +2 位作者 Melyna Aïcha Ntsan Bonaventure Max Lazare Peneme Arnaud Wilfrid Etou Ossibi 《Journal of Biosciences and Medicines》 2024年第10期361-372,共12页
A varied and balanced diet has always been essential in the optimal management of diabetes. The objective of this work was to evaluate dietary surveys among 50 diabetic patients hospitalized in the metabolic and endoc... A varied and balanced diet has always been essential in the optimal management of diabetes. The objective of this work was to evaluate dietary surveys among 50 diabetic patients hospitalized in the metabolic and endocrine diseases department of the Brazzaville Hospital and University Center. This survey was carried out using two methods: dietary history and 24-hour recall. The results relating to the dietary history revealed in the patients a dietary imbalance characterized by snacking at meals, non-compliance with a balanced diet and a high frequency of consumption of foods rich in simple sugar. and saturated fats. Regarding the 24-hour recall, the survey showed that the average blood sugar levels of hospitalized patients increased depending on the number of meals. This meant that these hyperglycemias (2 to 5 g/L) observed in these patients exceeded three meals per day and required, among other things, an increase in insulin intake or doses. The age groups of diabetic patients were also divided. These age groups had partly defined the types of diabetes encountered. Regarding body mass index, women had a body mass index greater than 30 kg/m2 compared to men. This increase in body mass index was explained by being overweight or even obese due to excess body fat. 展开更多
关键词 Diabetes dietary Survey dietary History 24-Hour Recall
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Resilience effects for household food expenditure and dietary diversity in rural western China 被引量:1
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作者 Xiao Han Kaiyu Lyu +1 位作者 Fengying Nie Yuquan Chen 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第2期384-396,共13页
A more resilient livelihood is increasingly recognized as an efficient way to improve vulnerable households’food security and optimize their dietary decisions.This study quantifies rural household resilience in weste... A more resilient livelihood is increasingly recognized as an efficient way to improve vulnerable households’food security and optimize their dietary decisions.This study quantifies rural household resilience in western China,identifies the three pillars(absorptive capacity,adaptive capacity,and transformative capacity)contribution to resilience,and then establishes the estimated Resilience Capacity Index(RCI)linked with food security and dietary diversity supported by the multiple indicator multiple cause(MIMIC)model.Results show that,despite geographical heterogeneity,the RCI consistently increased from 2015 to 2021.Households with a higher RCI inheriting better capacity to deal with risk and shocks are significantly and positively correlated with increasing food expenditure and diversifying food choices.It can be because resilient households will allocate more money to food expenditure instead of saving for livelihood uncertainty.Thus,policymakers can provide more incentives for rural households to adopt more dynamic and effective risk management strategies.This,in turn,could yield positive spillover effects by preventing human capital loss associated with dietary-related chronic diseases and mortality. 展开更多
关键词 RESILIENCE food expenditure dietary diversity China risk management
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Carbon Emission Effects Driven by Evolution of Chinese Dietary Structure from 1987 to 2020 被引量:1
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作者 ZHU Yuanyuan ZHANG Yan ZHU Xiaohua 《Chinese Geographical Science》 SCIE CSCD 2024年第1期181-194,共14页
Exploring carbon emission effects based on the evolution of residents’ dietary structure to achieve the carbon neutrality goal and mitigate climate change is an important task.This study took China as the research ob... Exploring carbon emission effects based on the evolution of residents’ dietary structure to achieve the carbon neutrality goal and mitigate climate change is an important task.This study took China as the research object(data excluding Hong Kong,Macao and Taiwan) and used the carbon emission coefficient method to quantitatively measure the food carbon emissions from 1987–2020,then analyzed the carbon emission effects under the evolution of dietary structure.The results showed that during the study period,the Chinese dietary structure gradually changed to a high-carbon consumption pattern.The dietary structure of urban residents developed to a balanced one,while that of rural residents developed to a high-quality one.During the study period,the per capita food carbon emissions and total food consumption of Chinese showed an increasing trend.The per capita food carbon emissions of residents in urban and rural showed an overall upward trend.The total food carbon emissions in urban increased significantly,while that in rural increased first and then decreased.The influence of beef and mutton on carbon emissions is the highest in dietary structure.Compared with the balanced dietary pattern,the food carbon emissions of Chinese residents had not yet reached the peak,but were evolving to a high-carbon consumption pattern. 展开更多
关键词 dietary structure structural evolution carbon emission effects carbon neutrality China
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Engineering Strategies for Suppressing the Shuttle Effect in Lithium–Sulfur Batteries 被引量:2
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作者 Jiayi Li Li Gao +7 位作者 Fengying Pan Cheng Gong Limeng Sun Hong Gao Jinqiang Zhang Yufei Zhao Guoxiu Wang Hao Liu 《Nano-Micro Letters》 SCIE EI CAS CSCD 2024年第1期187-221,共35页
Lithium–sulfur(Li–S)batteries are supposed to be one of the most potential next-generation batteries owing to their high theoretical capacity and low cost.Nevertheless,the shuttle effect of firm multi-step two-elect... Lithium–sulfur(Li–S)batteries are supposed to be one of the most potential next-generation batteries owing to their high theoretical capacity and low cost.Nevertheless,the shuttle effect of firm multi-step two-electron reaction between sulfur and lithium in liquid electrolyte makes the capacity much smaller than the theoretical value.Many methods were proposed for inhibiting the shuttle effect of polysulfide,improving corresponding redox kinetics and enhancing the integral performance of Li–S batteries.Here,we will comprehensively and systematically summarize the strategies for inhibiting the shuttle effect from all components of Li–S batteries.First,the electrochemical principles/mechanism and origin of the shuttle effect are described in detail.Moreover,the efficient strategies,including boosting the sulfur conversion rate of sulfur,confining sulfur or lithium polysulfides(LPS)within cathode host,confining LPS in the shield layer,and preventing LPS from contacting the anode,will be discussed to suppress the shuttle effect.Then,recent advances in inhibition of shuttle effect in cathode,electrolyte,separator,and anode with the aforementioned strategies have been summarized to direct the further design of efficient materials for Li–S batteries.Finally,we present prospects for inhibition of the LPS shuttle and potential development directions in Li–S batteries. 展开更多
关键词 Shuttle effect Designed strategies Li-S battery Lithium polysulfides
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The impact of Internet access on household dietary quality:Evidence from rural China 被引量:1
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作者 Yi Cui Qiran Zhao +1 位作者 Thomas Glauben Wei Si 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第2期374-383,共10页
Over the past few decades,the Internet has rapidly diffused across China.The spread of the Internet has had a profound economic and social impact on Chinese rural areas.Existing research shows that Internet access sig... Over the past few decades,the Internet has rapidly diffused across China.The spread of the Internet has had a profound economic and social impact on Chinese rural areas.Existing research shows that Internet access significantly impacts agricultural production and improves smallholder farmers’income.Beyond these,the Internet can affect other dimensions of social welfare.However,research about the impact of Internet access on dietary quality in rural China remains scarce.This study utilizes multi-period panel data from Fixed Observation Point in rural China from 2009 to 2015 to estimate the impact of Internet access on dietary quality and food consumption of rural households and conducts a causal analysis.Regression models with time and household fixed effects allow robust estimation while reducing potential issues of unobserved heterogeneity.The estimates show that Internet access has significantly increased rural household dietary quality(measured by the Chinese Diet Balance Index).Further research finds that Internet access has increased the consumption of animal products,such as aquatic and dairy products.We also examine the underlying mechanisms.Internet access improves dietary quality and food consumption mainly through increasing household income and food expenditure.These results encourage the promotion of Internet access as a valuable tool for nutritional improvements,especially in rural areas. 展开更多
关键词 dietary quality fixed effect model Internet access rural China
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Off-farm employment,agriculture production activities,and household dietary diversity in environmentally and economically vulnerable areas of Asia 被引量:1
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作者 Yunli Bai Xuanye Zeng +1 位作者 Chao Fu Linxiu Zhang 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第2期359-373,共15页
Access to off-farm employment has been expected to be a critical approach to ending hunger and all forms of malnutrition,two important targets of achieving Zero Hunger.This study aims to investigate the role of off-fa... Access to off-farm employment has been expected to be a critical approach to ending hunger and all forms of malnutrition,two important targets of achieving Zero Hunger.This study aims to investigate the role of off-farm employment in improving dietary diversity through substitution effect and complementary effect with agricultural production activities and income effect.This study adopts Poisson/Tobit/Probit/OLS regressions and the instrument variable method based on the primary survey data collected among 1,282 households at 12 sites in environmentally and economically vulnerable areas of China,Nepal,Cambodia,Thailand,and Myanmar in 2019.The results show that off-farm employment is positively associated with household dietary diversity and the consumption of flesh meat,fish and other aquatic animals,fruits,and milk and dairy products,which are rich in protein and micronutrients.The results of mechanism analysis show that off-farm employment contributes to household dietary diversity by improving crop diversity,especially for poor households,boosting the probability of livestock raising for households with the middle one-third disposal income,and increasing household income.The positive association between off-farm employment and household dietary diversity is much higher for households with the bottom one-third disposal income,low illiteracy,and from upper-middle income countries.These findings imply that off-farm employment does play a vital role in achieving multiple benefits of poverty alleviation,malnutrition reduction,and agrobiodiversity conservation in environmentally and economically vulnerable areas.However,it may enlarge the gaps in dietary diversity between households with low human capital and from low and lower-middle income countries and those with high human capital and from middle-high countries. 展开更多
关键词 off-farm employment dietary diversity income effect substitution effect complementary effect
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Drug resistance mechanisms in cancers:Execution of prosurvival strategies 被引量:1
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作者 Pavan Kumar Dhanyamraju 《Journal of Biomedical Research》 CAS CSCD 2024年第2期95-121,共27页
One of the quintessential challenges in cancer treatment is drug resistance.Several mechanisms of drug resistance have been described to date,and new modes of drug resistance continue to be discovered.The phenomenon o... One of the quintessential challenges in cancer treatment is drug resistance.Several mechanisms of drug resistance have been described to date,and new modes of drug resistance continue to be discovered.The phenomenon of cancer drug resistance is now widespread,with approximately 90% of cancer-related deaths associated with drug resistance.Despite significant advances in the drug discovery process,the emergence of innate and acquired mechanisms of drug resistance has impeded the progress in cancer therapy.Therefore,understanding the mechanisms of drug resistance and the various pathways involved is integral to treatment modalities.In the present review,I discuss the different mechanisms of drug resistance in cancer cells,including DNA damage repair,epithelial to mesenchymal transition,inhibition of cell death,alteration of drug targets,inactivation of drugs,deregulation of cellular energetics,immune evasion,tumor-promoting inflammation,genome instability,and other contributing epigenetic factors.Furthermore,I highlight available treatment options and conclude with future directions. 展开更多
关键词 cancer drug resistance MECHANISMS MICRORNAS treatment strategies
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Overview of the immunological mechanisms in hepatitis B virus reactivation:Implications for disease progression and management strategies 被引量:1
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作者 Hui Ma Qing-Zhu Yan +2 位作者 Jing-Ru Ma Dong-Fu Li Jun-Ling Yang 《World Journal of Gastroenterology》 SCIE CAS 2024年第10期1295-1312,共18页
Hepatitis B virus(HBV)reactivation is a clinically significant challenge in disease management.This review explores the immunological mechanisms underlying HBV reactivation,emphasizing disease progression and manageme... Hepatitis B virus(HBV)reactivation is a clinically significant challenge in disease management.This review explores the immunological mechanisms underlying HBV reactivation,emphasizing disease progression and management.It delves into host immune responses and reactivation’s delicate balance,spanning innate and adaptive immunity.Viral factors’disruption of this balance,as are interac-tions between viral antigens,immune cells,cytokine networks,and immune checkpoint pathways,are examined.Notably,the roles of T cells,natural killer cells,and antigen-presenting cells are discussed,highlighting their influence on disease progression.HBV reactivation’s impact on disease severity,hepatic flares,liver fibrosis progression,and hepatocellular carcinoma is detailed.Management strategies,including anti-viral and immunomodulatory approaches,are critically analyzed.The role of prophylactic anti-viral therapy during immunosuppressive treatments is explored alongside novel immunotherapeutic interventions to restore immune control and prevent reactivation.In conclusion,this compre-hensive review furnishes a holistic view of the immunological mechanisms that propel HBV reactivation.With a dedicated focus on understanding its implic-ations for disease progression and the prospects of efficient management stra-tegies,this article contributes significantly to the knowledge base.The more profound insights into the intricate interactions between viral elements and the immune system will inform evidence-based approaches,ultimately enhancing disease management and elevating patient outcomes.The dynamic landscape of management strategies is critically scrutinized,spanning anti-viral and immunomodulatory approaches.The role of prophylactic anti-viral therapy in preventing reactivation during immunosuppressive treatments and the potential of innovative immunotherapeutic interventions to restore immune control and proactively deter reactivation. 展开更多
关键词 Hepatitis B virus reactivation Immunological mechanisms Disease progression Management strategies Immune response
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Progress on Transition Metal Ions Dissolution Suppression Strategies in Prussian Blue Analogs for Aqueous Sodium-/Potassium-Ion Batteries 被引量:1
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作者 Wenli Shu Junxian Li +3 位作者 Guangwan Zhang Jiashen Meng Xuanpeng Wang Liqiang Mai 《Nano-Micro Letters》 SCIE EI CAS CSCD 2024年第7期142-168,共27页
Aqueous sodium-ion batteries(ASIBs)and aqueous potassium-ion batteries(APIBs)present significant potential for large-scale energy storage due to their cost-effectiveness,safety,and environmental compatibility.Nonethel... Aqueous sodium-ion batteries(ASIBs)and aqueous potassium-ion batteries(APIBs)present significant potential for large-scale energy storage due to their cost-effectiveness,safety,and environmental compatibility.Nonetheless,the intricate energy storage mechanisms in aqueous electrolytes place stringent require-ments on the host materials.Prussian blue analogs(PBAs),with their open three-dimensional framework and facile synthesis,stand out as leading candidates for aqueous energy storage.However,PBAs possess a swift capacity fade and limited cycle longevity,for their structural integrity is compromised by the pronounced dis-solution of transition metal(TM)ions in the aqueous milieu.This manuscript provides an exhaustive review of the recent advancements concerning PBAs in ASIBs and APIBs.The dissolution mechanisms of TM ions in PBAs,informed by their structural attributes and redox processes,are thoroughly examined.Moreover,this study delves into innovative design tactics to alleviate the dissolution issue of TM ions.In conclusion,the paper consolidates various strategies for suppressing the dissolution of TM ions in PBAs and posits avenues for prospective exploration of high-safety aqueous sodium-/potassium-ion batteries. 展开更多
关键词 Prussian blue analogs Transition metal ions dissolution Suppression strategies Aqueous sodium-ion batteries Aqueous potassium-ion batteries
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Dietary Diversity and Food Security Status among Cameroonian Adults Living in Semi-Urban Areas: A Cross-Sectional Study
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作者 Tonou Boris Ronald Tchuente Pauline Vervaine Hagbe +6 位作者 Eliane Flore Eyenga Kemadjou Ruth Edwige Dibacto Ngassa Dany Joël Ngoumen Fotso Janvier Aime Youovop Nguemto Roussel Guy Takuissu Judith Laure Ngondi Julius Enyong Oben 《Food and Nutrition Sciences》 CAS 2024年第7期548-564,共17页
Introduction: Food security is one of the greatest challenges that most African countries face. It is a concept that considers not only food quantity but also food quality. The objective of this study was to describe ... Introduction: Food security is one of the greatest challenges that most African countries face. It is a concept that considers not only food quantity but also food quality. The objective of this study was to describe dietary diversity and food security status at the individual level in Cameroonian populations. Methods: A total of 1180 men and women aged 20 and over and living in the West, North West, and Littoral regions of Cameroon were recruited. Data on dietary habits were collected through the frequency of consumption of various food groups. Dietary diversity was assessed using a 24-hour dietary recall. Food security status was determined by combining two indicators (food consumption score and individual food diversity score). Results: The mean dietary diversity score of the population was 3.53 ± 1.44, p Conclusion: The diet diversity of adults living in the West, North West, and Littoral regions of Cameroon is medium. Although half of the study population was food secure, there is a need to implement food security policies further to reduce food insecurity among the Cameroonian population. 展开更多
关键词 dietary Diversity Individual Food Security LITTORAL WEST North West Cameroon
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The Impact of Social Media on Dietary Behaviors and Body Image of College Students: A Qualitative Approach
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作者 Basem Azmy Saad Boutros Tabbetha D. Lopez Valencia Browning-Keen 《Food and Nutrition Sciences》 CAS 2024年第8期711-726,共16页
Background: The use of social media platforms for health and nutrition information has become popular among college students. Although social media made information readily accessible in different formats, nutritional... Background: The use of social media platforms for health and nutrition information has become popular among college students. Although social media made information readily accessible in different formats, nutritional misinformation promoted by influencers and non-experts caused negative impact on diet behavior and perception of body image. Previous research indicated that extensive use of social media was positively linked to disordered eating behaviors. Social media platforms like Facebook and Instagram that allow users to follow celebrities intensified exposure to influencers’ messages and images and resulted in negative moods and body dissatisfaction. Objective: This paper aims to explore the impact of social media on college students’ dietary behaviors and body image. Participants: 18 undergraduate students from a public university in the Southern United States were recruited through a mass email. Methods: A cross-sectional qualitative study of three focus groups was conducted. The focus groups were based on guiding open-ended questions. Atlas.ti was used to code and analyze the data using inductive and deductive codes. Results: Three main themes were identified. The conditions theme included elements that explain why and how social media influences the participants’ actions. The actions theme included eating behavior, physical activity, and dietary supplement intake. The consequences theme describes anticipated or actual outcomes of actions such as body image and ideal weight. Conclusions: Social media has had a negative influence on diet behaviors and a positive influence on physical activity. Evidence-based nutrition and weight management information is needed to thwart potential misinformation. 展开更多
关键词 Social Media Nutrition Information dietary Behavior Body Image College Students
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Plant-based dietary patterns and risk of esophageal cancer:A prospective cohort study spanning 17 years
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作者 Xiaorui Zhang Feifan He +6 位作者 Jiayue Li Ru Chen Xinqing Li Li Li Fen Liu Shaoming Wang Wenqiang Wei 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 2024年第1期36-45,共10页
Objective: Plant-based diets have multiple health benefits for cancers;however, little is known about the association between plant-based dietary patterns and esophageal cancer(EC).This study presents an investigation... Objective: Plant-based diets have multiple health benefits for cancers;however, little is known about the association between plant-based dietary patterns and esophageal cancer(EC).This study presents an investigation of the prospective associations among three predefined indices of plant-based dietary patterns and the risk of EC.Methods: We performed endoscopic screening for 15,709 participants aged 40-69 years from two high-risk areas of China from January 2005 to December 2009 and followed the cohort until December 31, 2022. The overall plant-based diet index(PDI), healthful plant-based diet index(h PDI), and unhealthful plant-based diet index(u PDI), were calculated using survey responses to assess dietary patterns. We applied Cox proportional hazard regression to estimate the multivariable hazard ratios(HRs) and 95% confidence intervals(95% CIs) of EC across 3plant-based diet indices and further stratified the analysis by subgroups.Results: The final study sample included 15,184 participants in the cohort. During a follow-up of 219,365person-years, 176 patients with EC were identified. When the highest quartile was compared with the lowest quartile, the pooled multivariable-adjusted HR of EC was 0.50(95% CI, 0.32-0.77) for h PDI. In addition, the HR per 10-point increase in the h PDI score was 0.42(95% CI, 0.27-0.66) for ECs. Conversely, u PDI was positively associated with the risk of EC, and the HR was 1.80(95% CI, 1.16-2.82). The HR per 10-point increase in the u PDI score was 1.90(95% CI, 1.26-2.88) for ECs. The associations between these scores and the risk of EC were consistent in most subgroups. These results remained robust in sensitivity analyses.Conclusions: A healthy plant-based dietary pattern was associated with a reduced risk of EC. Emphasizing the healthiness and quality of plant-based diets may be important for preventing the development of EC. 展开更多
关键词 Esophageal cancer DIET dietary pattern EPIDEMIOLOGY NUTRITION prospective cohort study
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Association of hypertension and plant-based dietary patterns on cognitive impairment: a nationwide cohort study in China
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作者 Fang Liang Jialin Fu +5 位作者 Gabrielle Turner-McGrievy Yechuang Wang Kai Ding Jing Zeng Justin B Moore Rui Li 《Food Science and Human Wellness》 SCIE CAS CSCD 2024年第6期3544-3552,共9页
This study investigated the association of hypertension with cognitive impairment and determined whether better adherence to plant-based diet(PBD)patterns may modify the association.We analyzed 4485 elderly individual... This study investigated the association of hypertension with cognitive impairment and determined whether better adherence to plant-based diet(PBD)patterns may modify the association.We analyzed 4485 elderly individuals with normal cognition at baseline from the Chinese Longitudinal Healthy Longevity Survey(2011−2018).Cognitive function was assessed by the Mini-mental State Examination(MMSE),and cognitive impairment was defined as an MMSE score below 18 points.Diet patterns were assessed using the overall plant-based diet index(PDI),healthful plant-based diet index(hPDI),and unhealthful plant-based diet index(uPDI)derived from a simplified food frequency questionnaire(FFQ).Blood pressure was measured through physical examination.Cox proportional hazard regression and restricted cubic spline were performed.Participants with hypertension had an increased risk of cognitive impairment compared with normal group.The associations between hypertension and cognitive impairment were more pronounced among participants with lower PDI than those with higher PDI,among participants with lower hPDI than those with higher hPDI,and among participants with higher uPDI than those with lower uPDI.A healthful PBD pattern may attenuate hypertension-induced cognitive impairment,while an unhealthful PBD pattern may exacerbate hypertensioninduced cognitive impairment in elderly.Adherence to healthful PBD pattern could be used to prevent or mitigate adverse neurological effects in the hypertensive population. 展开更多
关键词 Cognitive impairment HYPERTENSION Plant-based dietary pattern Chinese older adults COHORT
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Examining dietary interventions in Crohn’s disease
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作者 Lynna Chen Ashish Srinivasan Abhinav Vasudevan 《World Journal of Gastroenterology》 SCIE CAS 2024年第34期3868-3874,共7页
This editorial builds on the article by Shakhshir et al.We conducted an overview of evidence-based dietary interventions in adults with inflammatory bowel disease(IBD).In the IBD population,there may be a role for the... This editorial builds on the article by Shakhshir et al.We conducted an overview of evidence-based dietary interventions in adults with inflammatory bowel disease(IBD).In the IBD population,there may be a role for the Mediterranean diet due to its anti-inflammatory effects,long-term sustainability,and role in improving cardiovascular health.In active Crohn’s disease,the use of exclusive enteral nutrition,the Crohn’s disease exclusion diet,or the specific carbohydrate diet may be used as a short-term adjunct to medical therapy and may improve mucosal healing.The low-FODMAP diet can assist in reducing symptoms for patients without evidence of active bowel inflammation.As interest in nutritional therapy increases amongst clinicians and patients alike,it is integral that dietary therapies are understood and discussed in routine management of patients with IBD as part of holistic care,ideally through a multidisciplinary setting with involvement of experienced dietitians.This serves to improve clinician-patient engagement and reduce complications of IBD including micro and micronutrient deficiencies. 展开更多
关键词 Inflammatory bowel disease NUTRITION dietary therapies INFLAMMATION MALNUTRITION
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LDAS&ET-AD:Learnable Distillation Attack Strategies and Evolvable Teachers Adversarial Distillation
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作者 Shuyi Li Hongchao Hu +3 位作者 Xiaohan Yang Guozhen Cheng Wenyan Liu Wei Guo 《Computers, Materials & Continua》 SCIE EI 2024年第5期2331-2359,共29页
Adversarial distillation(AD)has emerged as a potential solution to tackle the challenging optimization problem of loss with hard labels in adversarial training.However,fixed sample-agnostic and student-egocentric atta... Adversarial distillation(AD)has emerged as a potential solution to tackle the challenging optimization problem of loss with hard labels in adversarial training.However,fixed sample-agnostic and student-egocentric attack strategies are unsuitable for distillation.Additionally,the reliability of guidance from static teachers diminishes as target models become more robust.This paper proposes an AD method called Learnable Distillation Attack Strategies and Evolvable Teachers Adversarial Distillation(LDAS&ET-AD).Firstly,a learnable distillation attack strategies generating mechanism is developed to automatically generate sample-dependent attack strategies tailored for distillation.A strategy model is introduced to produce attack strategies that enable adversarial examples(AEs)to be created in areas where the target model significantly diverges from the teachers by competing with the target model in minimizing or maximizing the AD loss.Secondly,a teacher evolution strategy is introduced to enhance the reliability and effectiveness of knowledge in improving the generalization performance of the target model.By calculating the experimentally updated target model’s validation performance on both clean samples and AEs,the impact of distillation from each training sample and AE on the target model’s generalization and robustness abilities is assessed to serve as feedback to fine-tune standard and robust teachers accordingly.Experiments evaluate the performance of LDAS&ET-AD against different adversarial attacks on the CIFAR-10 and CIFAR-100 datasets.The experimental results demonstrate that the proposed method achieves a robust precision of 45.39%and 42.63%against AutoAttack(AA)on the CIFAR-10 dataset for ResNet-18 and MobileNet-V2,respectively,marking an improvement of 2.31%and 3.49%over the baseline method.In comparison to state-of-the-art adversarial defense techniques,our method surpasses Introspective Adversarial Distillation,the top-performing method in terms of robustness under AA attack for the CIFAR-10 dataset,with enhancements of 1.40%and 1.43%for ResNet-18 and MobileNet-V2,respectively.These findings demonstrate the effectiveness of our proposed method in enhancing the robustness of deep learning networks(DNNs)against prevalent adversarial attacks when compared to other competing methods.In conclusion,LDAS&ET-AD provides reliable and informative soft labels to one of the most promising defense methods,AT,alleviating the limitations of untrusted teachers and unsuitable AEs in existing AD techniques.We hope this paper promotes the development of DNNs in real-world trust-sensitive fields and helps ensure a more secure and dependable future for artificial intelligence systems. 展开更多
关键词 Adversarial training adversarial distillation learnable distillation attack strategies teacher evolution strategy
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Eradication Treatment of Helicobacter pylori Infection: Evaluation of Therapeutic Strategies in N’Djamena
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作者 Mayanna Habkréo Ali Mahamat Moussa +5 位作者 Tahir Mahamat Saleh Djerabet Franckly Fany Haby Mairé Dehainssala Adama Ngaré Mahamat Ali Hachim 《Open Journal of Gastroenterology》 CAS 2024年第2期59-67,共9页
Background: Helicobacter pylori (Hp) infection is the most widespread bacterial infection in the world. The infection is generally acquired in childhood, but can persist into adulthood. Eradication therapy has undergo... Background: Helicobacter pylori (Hp) infection is the most widespread bacterial infection in the world. The infection is generally acquired in childhood, but can persist into adulthood. Eradication therapy has undergone several modifications. The aim of this study was to evaluate the different therapeutic strategies used in the eradication of Helicobacter pylori infection in the Centre Hospitalier Universitaire La Reference Nationale of N’Djaména. Patients and Methods: This was a prospective, descriptive analytical study spread over one year, from September 2021 to September 2022. Patients at least 15 years of age presenting with dyspeptic symptoms, seen consecutively in a hepato-gastroenterology consultation and with a positive stool test for H. pylori infection, were included in the study. Equally, 1/3 of patients were treated with dual or triple therapy. The remaining third received quadritherapy. Results: A total of 268 patients were included in the study (mean age 38.40 ± 14.66 with extremes of 16 and 80 years). Males predominated in 58% of cases. Overall therapeutic efficacy was 88.9%. According to different therapeutic strategies, efficacy was 90.75% for dual therapy with PPI (Rabeprazole) and Amoxicillin. On the other hand, efficacy was 87% and 88.88% for PPI-based triple therapy and dual antibiotic therapy, and for PPI-based quadruple therapy and triple antibiotic therapy. Conclusion: H. pylori infection is a common disease in Chad. Dual therapy with rabeprazole combined with a high dose of amoxicillin over a period of at least two weeks showed similar if not better efficacy than triple or quadruple therapy. 展开更多
关键词 Helicobacter pylori Therapeutic strategies ERADICATION DYSPEPSIA CHAD
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Maternal dietary patterns associated with bone density in Chinese lactating women and infants at 6 months postpartum:a prospective study using data from 2018-2019
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作者 Yalin Zhou Xiaoyu Zhu +7 位作者 Ying Lü Runlong Zhao Hanxu Shi Wanyun Ye Zhang Wen Rui Li Hanming Huang Yajun Xu 《Food Science and Human Wellness》 SCIE CAS CSCD 2024年第5期2668-2676,共9页
This cohort study was designed to explore the relationship between maternal dietary patterns(DPs)and bone health in Chinese lactating mothers and infants.We recruited 150 lactating women at 1-month postpartum.The esti... This cohort study was designed to explore the relationship between maternal dietary patterns(DPs)and bone health in Chinese lactating mothers and infants.We recruited 150 lactating women at 1-month postpartum.The estimated bone mineral density(eBMD)of subjects’calcanei and the information on dietary intake were collected.After 5-month follow-up,the eBMD of mothers and their infants were measured again.Factor analysis was applied to determine maternal DPs.General linear models were used to evaluate the association between maternal DPs and maternal eBMD loss or infants’eBMD.With all potential covariates adjusted,Factor 2(high intake of whole grains,tubers,mixed beans,soybeans and soybean products,seaweeds,and nuts)showed a positive association with the changes of maternal eBMD(β=0.16,95%CI:0.005,0.310).Factor 3(high intake of soft drinks,fried foods,and puffed foods)was inversely correlated with the changes of maternal eBMD(β=-0.22,95%CI:-0.44,0.00).The changes of maternal eBMD were positively associated with 6-month infants’eBMD(β=0.34,95%CI:0.017,0.652).In conclusion,Factor 2 might contribute to the maintenance of eBMD in lactating women,while Factor 3 could exacerbate maternal eBMD loss.Additionally,the changes of maternal eBMD presented a positive correlation with 6-month infants’eBMD. 展开更多
关键词 dietary patterns Estimated bone mineral density Lactating women
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Comprehensive analysis of advanced glycation end-products in commonly consumed foods:presenting a database for dietary AGEs and associated exposure assessment
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作者 Qiaozhi Zhang Huatao Li +7 位作者 Ruixing Zheng Lili Cao Shufen Zhang Shuifeng Zhang Huadong Sheng Yuhao Jiang Yanbo Wang Linglin Fu 《Food Science and Human Wellness》 SCIE CAS CSCD 2024年第4期1917-1928,共12页
Advanced glycation end-products(AGEs)are a group of heterogeneous compounds formed in heatprocessed foods and are proven to be detrimental to human health.Currently,there is no comprehensive database for AGEs in foods... Advanced glycation end-products(AGEs)are a group of heterogeneous compounds formed in heatprocessed foods and are proven to be detrimental to human health.Currently,there is no comprehensive database for AGEs in foods that covers the entire range of food categories,which limits the accurate risk assessment of dietary AGEs in human diseases.In this study,we first established an isotope dilution UHPLCQq Q-MS/MS-based method for simultaneous quantification of 10 major AGEs in foods.The contents of these AGEs were detected in 334 foods covering all main groups consumed in Western and Chinese populations.Nε-Carboxymethyllysine,methylglyoxal-derived hydroimidazolone isomers,and glyoxal-derived hydroimidazolone-1 are predominant AGEs found in most foodstuffs.Total amounts of AGEs were high in processed nuts,bakery products,and certain types of cereals and meats(>150 mg/kg),while low in dairy products,vegetables,fruits,and beverages(<40 mg/kg).Assessment of estimated daily intake implied that the contribution of food groups to daily AGE intake varied a lot under different eating patterns,and selection of high-AGE foods leads to up to a 2.7-fold higher intake of AGEs through daily meals.The presented AGE database allows accurate assessment of dietary exposure to these glycotoxins to explore their physiological impacts on human health. 展开更多
关键词 Advanced glycation end-products Maillard reaction Processed foods dietary database Exposure assessment
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Review on dietary supplements as an effective improvement of Alzheimer's disease:focus on structures and mechanisms
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作者 Sheng Li Yinling Wei +3 位作者 Zhenzhen Liang Lingli Guo Xiaojiang Hao Yu Zhang 《Food Science and Human Wellness》 SCIE CAS CSCD 2024年第4期1787-1805,共19页
Alzheimer’s disease(AD),the major form of neurodegenerative diseases that can severely impede normal cognitive function,makes it one of the most common fatal diseases.There are currently over 50 million AD patients w... Alzheimer’s disease(AD),the major form of neurodegenerative diseases that can severely impede normal cognitive function,makes it one of the most common fatal diseases.There are currently over 50 million AD patients worldwide.The neuropathology of AD is perplexing and there is a scarcity of disease-modifying treatments.Currently,early diagnosis of AD has been made possible with the discovery of biological markers associated with pathology,providing strong support for the improvement of the disease status.The search for inhibitors of AD markers from dietary supplements(DSs)has become a major hot topic.Especially with the widespread use of DSs,DSs containing polyphenols,alkaloids,terpenes,polysaccharides and other bioactive components can prevent AD by reducing Aβdeposition,inhibiting tau protein hyperphosphorylation,reconstructing synaptic dysfunction,weakening cholinesterase activity,regulating mitochondrial oxidative stress,neuronal inflammation and apoptosis.This review summarizes the anti-AD effects of the main DSs and their bioactive constituents,as well as the potential molecular mechanisms covers from 2017 to 2023.Additionally,we discussed the opportunities and challenges faced by DSs in the process of AD prevention and treatment,aiming to further provide new perspectives for functional food development. 展开更多
关键词 dietary supplements Bioactive ingredients Alzheimer’s disease Mechanism of action
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Accurate models and nutritional strategies for specific oxidative stress factors: Does the dose matter in swine production?
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作者 Changming Hong Yujian Huang +6 位作者 Shuting Cao Li Wang Xuefen Yang Shenglan Hu Kaiguo Gao Zongyong Jiang Hao Xiao 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2024年第2期519-534,共16页
Oxidative stress has been associated with a number of physiological problems in swine,including reduced production efficiency.Recently,although there has been increased research into regulatory mechanisms and antioxid... Oxidative stress has been associated with a number of physiological problems in swine,including reduced production efficiency.Recently,although there has been increased research into regulatory mechanisms and antioxidant strategies in relation to oxidative stress-induced pig production,it remains so far largely unsuccessful to develop accurate models and nutritional strategies for specific oxidative stress factors.Here,we discuss the dose and dose intensity of the causes of oxidative stress involving physiological,environmental and dietary factors,recent research models and the antioxidant strategies to provide theoretical guidance for future oxidative stress research in swine. 展开更多
关键词 Accurate models DOSE Nutritional strategies Oxidative stress SWINE
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