The development of cancer is a complex process that requires the participation of many factors,including mutations in genes, regulation of signaling pathways, disruption of homeostasis, and failure of self-monitoring ...The development of cancer is a complex process that requires the participation of many factors,including mutations in genes, regulation of signaling pathways, disruption of homeostasis, and failure of self-monitoring mechanisms. Sufficient evidence has展开更多
In this article,we relocated the seismic source location of the earthquakes in the Muli area of Sichuan,inverted the focal mechanism of the larger earthquakes and analyzed the relationship between the water level of t...In this article,we relocated the seismic source location of the earthquakes in the Muli area of Sichuan,inverted the focal mechanism of the larger earthquakes and analyzed the relationship between the water level of the Jinping reservoir and the frequency of the earthquake swarm. The results show that:( 1) The epicenters of the relocated small earthquake swarms are distributed in a seismic zone,and the earthquake focal depths were in the range of 0- 12 km.( 2) By analyzing the earthquake swarm spatial distribution,we found that the swarms were generated by one branch fault on the west of Xiaojinhe fault.( 3) The focal mechanism of the three earthquakes with magnitude greater than 4. 0 is significantly different,with the shallow source thrust events affected by vertical stress,and the strike-slip events are related to regional stress tectonic activity.展开更多
Objective To investigate the effects of different doses of vecuronium on ventilatory function and mechanics of breathing during elective laparoscopic cholecystectomy. Methods Sixty - three ASA Ⅰ - Ⅱ patients aged 29...Objective To investigate the effects of different doses of vecuronium on ventilatory function and mechanics of breathing during elective laparoscopic cholecystectomy. Methods Sixty - three ASA Ⅰ - Ⅱ patients aged 29 -57 yr were randomly divided into 3 groups of twenty-one: group Ⅰ received vecuronium 1 ± ED95 , group Ⅱ 2 ± ED95 and group Ⅲ ± ED95. Patients with respiratory disease were excluded. The patients were premedicated with intramuscular scopolamine 0 . 3 mg and oral diazepam 0 . 1 mg· kg-1 . Anesthesia was induced with fentanyl 2 μg ·kg-1 ,propofol 2 mg·kg-1 and succinylcholine 1. 5 mg· kg-1 and maintained with 1.0% -1.5% isoflurance and intermittent iv boluses of propofol 1 mg·kg when needed. Vecuronium 1 ± ED95 ( group Ⅰ ) or 2 ± ED95 (group Ⅱ ) or 3 ± ED95 (group Ⅲ ) was given iv after succinylcholine when TOF showed that T1 】 70 % . The patients were mechanically ventilated. VT was set at 10 ml ·kg-1 and respiratory rate at 12 bpm. End-tidal PCO2 was maintained at 30 -展开更多
The effects of various cooling paths on uniformity of through-thickness microstructure and mechanical properties of X80 pipeline steel of 22.0 mm in thickness were studied. The finite difference method was employed to...The effects of various cooling paths on uniformity of through-thickness microstructure and mechanical properties of X80 pipeline steel of 22.0 mm in thickness were studied. The finite difference method was employed to calculate the temperature field during cooling. It was confirmed by the experimental result and temperature field calculation that the optimizing process was achieved by the ultra-fast cooling with medium cooling capacity（cooling rate of ＊23 K/s）followed by ultimate cooling capacity（cooling rate of ＊50 K/s）. After optimization, the experimental steel displayed much uniform microstructure and the deviation of through-thickness hardness was controlled within 20 HV. In addition,the yield strength, tensile strength and elongation of the experimental steel were 621, 728 MPa and 21.5%, respectively,meeting the requirements of the API standard for X80 pipeline steels.展开更多
基金supported by the grants from the Outstanding Academic Leaders Plan of Shanghai [Grant No.2018BR07]the National Science Foundation of China [Grant No.81572061]+1 种基金Program for Young Medical Technicians(Clinical Examination)in Shanghai [2016]05Shanghai Health and Family Planning Commission Clinical Research Project for Health Industry [Grant No.20184Y0199]
文摘The development of cancer is a complex process that requires the participation of many factors,including mutations in genes, regulation of signaling pathways, disruption of homeostasis, and failure of self-monitoring mechanisms. Sufficient evidence has
基金sponsored by the Regular Project of Earthquake Monitoring and Prediction in 2016(16C23ZX327)
文摘In this article,we relocated the seismic source location of the earthquakes in the Muli area of Sichuan,inverted the focal mechanism of the larger earthquakes and analyzed the relationship between the water level of the Jinping reservoir and the frequency of the earthquake swarm. The results show that:( 1) The epicenters of the relocated small earthquake swarms are distributed in a seismic zone,and the earthquake focal depths were in the range of 0- 12 km.( 2) By analyzing the earthquake swarm spatial distribution,we found that the swarms were generated by one branch fault on the west of Xiaojinhe fault.( 3) The focal mechanism of the three earthquakes with magnitude greater than 4. 0 is significantly different,with the shallow source thrust events affected by vertical stress,and the strike-slip events are related to regional stress tectonic activity.
文摘Objective To investigate the effects of different doses of vecuronium on ventilatory function and mechanics of breathing during elective laparoscopic cholecystectomy. Methods Sixty - three ASA Ⅰ - Ⅱ patients aged 29 -57 yr were randomly divided into 3 groups of twenty-one: group Ⅰ received vecuronium 1 ± ED95 , group Ⅱ 2 ± ED95 and group Ⅲ ± ED95. Patients with respiratory disease were excluded. The patients were premedicated with intramuscular scopolamine 0 . 3 mg and oral diazepam 0 . 1 mg· kg-1 . Anesthesia was induced with fentanyl 2 μg ·kg-1 ,propofol 2 mg·kg-1 and succinylcholine 1. 5 mg· kg-1 and maintained with 1.0% -1.5% isoflurance and intermittent iv boluses of propofol 1 mg·kg when needed. Vecuronium 1 ± ED95 ( group Ⅰ ) or 2 ± ED95 (group Ⅱ ) or 3 ± ED95 (group Ⅲ ) was given iv after succinylcholine when TOF showed that T1 】 70 % . The patients were mechanically ventilated. VT was set at 10 ml ·kg-1 and respiratory rate at 12 bpm. End-tidal PCO2 was maintained at 30 -
基金supported by the National Natural Science Foundation of China(No.51234002)the Fundamental Research Funds for the Central Universities(N130407001)
文摘The effects of various cooling paths on uniformity of through-thickness microstructure and mechanical properties of X80 pipeline steel of 22.0 mm in thickness were studied. The finite difference method was employed to calculate the temperature field during cooling. It was confirmed by the experimental result and temperature field calculation that the optimizing process was achieved by the ultra-fast cooling with medium cooling capacity（cooling rate of ＊23 K/s）followed by ultimate cooling capacity（cooling rate of ＊50 K/s）. After optimization, the experimental steel displayed much uniform microstructure and the deviation of through-thickness hardness was controlled within 20 HV. In addition,the yield strength, tensile strength and elongation of the experimental steel were 621, 728 MPa and 21.5%, respectively,meeting the requirements of the API standard for X80 pipeline steels.
