Effects of Different Treatments on Seed Germination of Gagea nigra

According to different mechanisms of dormancy,seeds of Gagea nigra L.Z.Shue were treated with different methods so as to investigate the effects of different treatments on seed germination of G.nigra.The results showed that at 4 ℃,the seeds of G.nigra began to germinate on day 32 with germination period of 80 d and germination rate of 72%;room temperature（25 ℃） and acid and alkali treatments were all unsuitable for the germination of G.nigra seeds;no significant differences were found in germination rate of G.nigra seeds among warm water（50℃）,ultrasound and 200 mg/L GA_3treatments（P 0.05）;seed coat-removing treatment effectively promoted the germination of G.nigra seeds（P =0.002 0.01） with germination rate of 88%;seed coat piercing ＋ 200 mg/L GA_3 and 500 mg/L GA_3＋15% H_2O_2 treatments effectively promoted the germination of G.nigra seeds with germination rates of 84% and 82%,respectively（P0.05）;the germination vigor of G.nigra seeds in the seed coat piercing ＋ 200 mg/L GA_3 treatment was highest,and it was significantly higher than those in the other treatments.

Effects of Different Fertilization Treatments on Biological Activity of Reclaimed Soil

As per randomized block design, the research had different fertilizer treatments, and the organic matter, respiration, enzyme activity and microbial carbon and nitrogen in reclaimed soil were studied. Fertilization schemes were as follows： The treatment without fertilizers（CK）, the treatment with chemical fertilizers（C）, the treatment with chemical fertilizers and bacterial fertilizer（CB）, the treatment with organic fertilizer and chemical fertilizers（CM）, and the treatment with chemical fertilizers, organic fertilizer and bacterial fertilizer（CMB）. The results showed： Four fertilization treatments could improve the content of soil organic matter. CMB, CM and CB could significantly improve the soil respiration. Organic fertilizer and fertilizer could significantly improve soil enzyme activity, In different growth stages the CMB treatment had highest urease and phosphatase.The most significant in the treatment content of sucrose was CM. Organic fertilizer and microbial fertilizer can significantly improve the microbial carbon and nitrogen in soil. For the microbial biomass carbon, the CMB treatment increased by 11%-34% than CB treatment, and 35%-63% than C treatment. In terms of microbial nitrogen CMB, CM respectively increased by 31%-51% than CB treatment, and 52%-100% compared with C. In the process of land reclamation, we should combine the organic fertilizer, microbial fertilizer and inorganic fertilizer. Only in this way can soil biological activity be accelerated, soil microbial environment improved, and the ripening increased soil nutrient and soil cultivation be enhanced.

Effect of Different Treatment Rapeseeds on Activity of Cellulose Enzyme in Sheep

The purpose of the experiment is to research the effect of different rapeseed treatments feeding on activity of cellulose enzyme in sheep. Eight male adults of semi-fine wool sheep breeds with the same weight and permanent rurnen cannulas were selected according to 4×4 Latin square design to determine the effect of different rapeseed treatment groups including crushed rapeseed, whole rapeseed, extruded rapeseed （dietary lipid content of =67 g·kg^-1） and control group （dietary lipid content of =30 g·kg^-1） on activity dynamic variation of ruminal celluolytic enzyme in sheep. The results showed that ruminal fluid pH matched up to the condition of fiber degradation and growth of cellulolytic bacterium when fed four diets; but there was significant difference （P〈0.05） for the activity of microcrystalline cellulose, glucanase, salicin enzyme involved in ruminal fiber degradation after fed 2, 4, 6 h.

Mutagenicity and Genotoxicity of Organic Extracts from Finished Water with Different Treatment Process

Purification of surface water is widely practiced with conventional water treatment processes like coagulation-flocculation, sedimentation, filtration,and disinfection. Some reports have specified that conventional wastewater purification processes do not effectively remove many chemical contaminants,

Effect of intervention treatment from different stages on prognosis in children with central coordination disturbance

BACKGROUND： Central coordination disturbance is regarded as the early-stage symptom of brain injury-induced cerebral palsy. This disease manifests itself as motor disorder, abnormal attitudinal reflex and muscular tension. Early intervention may improve its prognosis. OBJECTIVE： To observe the effects of intervention treatment from different stages on the prognosis of central coordination disturbance following brain injury in children patients. DESIGN： A contrast observation experiment SETTING： Department of Neurology and Rehabilitation, Urumqi Children＇s Hospital PARTICIPANTS ： Totally 151 children who were diagnosed as central coordination disturbance from January 2002 to December 2003 in the Department of Neurology and Rehabilitation of Urumqi Children＇s Hospital were recruited. All the children patients, including 101 male and 50 female, aged from 3 months to 1 year old, met the diagnosis criteria of central coordination disturbance from Vojta. They were divided into slight, moderate and severe abnormity according to Vojta attitudinal reflex. All 151 patients were divided into 2 groups according to their age at diagnosis： 3-6 months old group （n=74）, 62 severe, 10 moderate and 2 slight; 7-12 months old group （n=77）, 66 severe, 7 moderate and 4 slight. All the relatives of children patients were informed of the experiment. METHODS： ① Both groups received physical training （PT） as the main treatment; Hand training was given if necessary. All of the patients received additional hyperbaric oxygen therapy, bioelectric therapy, scalp acupuncture, drug treatment and family training. The importance of integration of hospital and family based rehabilitation was stressed. Those who did not catch up with the normal development or had abnormal reflexes continued to receive treatment. ② Around the age of 2 years old, all children did a final evaluation using Bayley Scales of Infant Development （BSID）. Mental development index （MDI） and physical development index （PDI） were taken as evaluative criteria. Children with scores 80 and above on MDI and PDI were considered to have normal motor and mental development; 79 and below were considered delayers. The Diagnostic Criteria of Cerebral Palsy and Infantecondary School Social Adaptation Scale were used in the final evaluation[scores ≤5 was extremely severe （extremely severe cerebral palsy）, 6 was severe（severe cerebral palsy）, 7 was moderate（moderate cerebral palsy）, 8 was slight（slight cerebral palsy）, 9 was borderline（slight cerebral palsy）, 10 was normal, 11 was above average, 12 was excellent and ≥13 was extremely excellent]. ③ Final evaluative results of 2 groups were compared. And u test was used for the comparison of Bayley development index and Chi-square test for the comparison of normalization rate. MAIN OUTCOME MEASURES： BSID MDI and PDI as well as the normalization rate of motor function and mental behavior of children patients at 2 years old. RESULTS： Totally 151 children patients entered the stage of result analysis. ①Two groups of children patients were given integrated rehabilitation therapy , and evaluated at 2 years old . The 3-6 months old group had higher MDI and PDI than the 7-12 months old group （91.81＋19.99 vs 71.93＋18.98;91.55＋23.61 vs 68.95＋23.51, u=6.265,5.894,P 〈 0.01 ）.②After being given integrated rehabilitation therapy, children patients of 3-6 months old group had significantly higher normalization rate of motor function and mental behavior than 7-12 months old group （73% ,27%,X2=29.723 9,P 〈 0.01 ）. ③Six slight and 17 moderate central coordination disturbance children of 2 groups all completely recovered; After intervention treatment, among 128 severe central coordination disturbance children, 52 recovered and 76 were still abnormal, in which, 43 slight cerebral palsy, 18 moderate cerebral palsy, 5 severe cerebral palsy and 10 extremely severe cerebral palsy. CONCLUSION： To perform integrated intervention treatment before 6 months old can better improve and promote mental and physical development levels of children patients with central coordination disturbance after brain injury than 6 months later.

Analysis of the Effect of Different Treatment Schemes on Helicobacter Pylori Infection on Improving the Quality of Life of Patients

Objective:To analyze the effect of different treatment schemes on the quality of life of patients with Helicobacter pylori infection.Methods:From June 2019 to November 2020,96 patients with Helicobacter pylori infection were selected and randomly assigned Combined treatment with omeprazole,amoxicillin and clarithromycin was named group A;Group B was treated with omeprazole,amoxicillin,clarithromycin and colloidal bismuth pectin;Group C was given omeprazole,amoxicillin,clarithromycin and metronidazole.Results:The symptom score and gastroscope score of group B or C were lower than those of group A(P<0.05);The incidence of adverse reactions and HP eradication rate in group C were lower than those in group B,and those in group B were lower than those in group A(P<0.05);The quality of life score of group C was higher than that of group B,and that of group B was higher than that of group A,P<0.05.Conclusions:The sequential therapy of omeprazole,amoxicillin,clarithromycin and metronidazole in patients with Helicobacter pylori infection can improve the HP eradication rate,improve the quality of life of patients,which is safe and efficient.

Cone beam computed tomography-guided differences among registration methods for lung cancer and the effects of tumor position,treatment model,and tumor size on positioning errors

Objective To explore the differences in three different registration methods of cone beam computed tomography(CBCT)-guided down-regulated intense radiation therapy for lung cancer as well as the effects of tumor location,treatment mode,and tumor size on registration.Methods This retrospective analysis included 80 lung cancer patients undergoing radiotherapy in our hospital from November 2017 to October 2019 and compared automatic bone registration,automatic grayscale(t+r)registration,and automatic grayscale(t)positioning error on the X-,Y-,and Z-axes under three types of registration methods.The patients were also grouped according to tumor position,treatment mode,and tumor size to compare positioning errors.Results On the X-,Y-,and Z-axes,automatic grayscale(t+r)and automatic grayscale(t)registration showed a better trend.Analysis of the different treatment modes showed differences in the three registration methods;however,these were not statistically significant.Analysis according to tumor sizes showed significant differences between the three registration methods(P<0.05).Analysis according to tumor positions showed differences in the X-and Y-axes that were not significant(P>0.05),while the autopsy registration in the Z-axis showed the largest difference in the mediastinal and hilar lymph nodes(P<0.05).Conclusion The treatment mode was not the main factor affecting registration error in lung cancer.Three registration methods are available for tumors in the upper and lower lungs measuring<3 cm;among these,automatic gray registration is recommended,while any gray registration method is recommended for tumors located in the mediastinal hilar site measuring<3 cm and in the upper and lower lungs≥3 cm.

Time difference based measurement of ultrasonic cavitations in wastewater treatment

Intensity of cavitation is significant in ultrasonic wastewater treatment,but is complicated to measure.A time difference based method of ultrasonic cavitation measurement is proposed.The time differences at different powers of 495 kHz ultrasonic are measured in experiment in comparison with conductimetric method.Simulation results show that time difference and electrical conductivity are both approximately positive proportional to the ultrasonic power.The degradation of PNP solution verifies the availability in wastewater treatment by using ultrasonic.

部分嵌套式设计在中医药“同病异治”疗效评价中的应用及方法学探索

目的本研究针对中医学同病异治、辨证论治的特征,引入部分嵌套式设计。方法部分嵌套式设计以复杂干预对照标准化治疗,中医组按“证型-治法-方药”分割为多个子集(存在嵌套结构),对照组采用标准化西医治疗(无嵌套结构);并以一项溃疡性结肠炎“同病异治”数据为例,套用该设计类型并采用多水平模型分析。结果部分嵌套式设计符合“同病异治”诊疗特征并满足循证评价的设计要求,通过多水平模型可实现类似数据结构的分析。结论利用部分嵌套式设计能实现对“同病异治”整体效果的评价,可为中医药临床疗效评价提供方法学参考。

上海市典型城镇污水处理厂温室气体排放特征研究

以上海市2家典型城镇污水处理厂Ⅰ和Ⅱ为例,核算近年来因直接排放和间接排放产生的碳排放量。污水厂Ⅰ和Ⅱ的碳排放主要来自于对N污染物的处理,分别占总碳排放的61.36%、46.18%;污水厂Ⅰ电耗产生的碳排放从2015年到2022年翻了一番,污水厂Ⅱ电耗产生的碳排放占比达45.20%。2家污水厂单位进水的总排放强度分别为1065.02、1110.26 g CO_(2)eq/m^(3),与国内某些厂相比属较高水平;与IPCC缔约国相比,2座厂人均碳排放强度分别为1.76、1.93 kg CO_(2)eq/人,属较高水平。此研究运用指南进行核算,有助于了解上海污水厂碳排放基本情况,进而细化核算方法、完善排放因子,是减污降碳、实施双控的基础工作。

不同采后处理对恭城月柿褐变、活性氧代谢及糖类的影响

本文分析了有氧、真空和真空+1-MCP三种采后处理方式对脱涩后柿子贮藏过程中果实褐变、活性氧代谢和糖类的影响,并对褐变与各指标的相关性进行分析。真空和真空+1-MCP组柿子贮藏过程中的褐变指数BI低于有氧组,其中真空+1-MCP组褐变程度最低;三种采后处理柿子贮藏过程中SOD、APX活性分别呈下降和上升的趋势,真空组柿子SOD活性最低,真空和真空+1-MCP条件下柿子APX活性高于有氧组;真空和真空+1-MCP抑制柿子CAT活性的增加,减少H2O2积累,同时抑制羟自由基的能力和抗坏血酸含量较低。真空和真空+1-MCP组柿子还原糖含量低于有氧组,其中真空+1-MCP组增加最慢,从贮藏开始时的14.10%增加至12 d时的14.87%;真空+1-MCP组柿子果胶含量下降缓慢。相关性分析可知,不同采后处理柿子贮藏过程中柿子褐变与各指标的相关性并不相同,但柿子褐变指数BI均与果胶呈负相关,与还原糖呈正相关。综合可知真空和真空+1-MCP条件更有利于抑制脱涩后月柿的褐变。

桂枝茯苓丸化裁异病同治血瘀型功能性肛门直肠痛经验

目的总结运用桂枝茯苓丸化裁治疗血瘀型功能性肛门直肠痛的诊疗思路。方法通过研究古籍、搜集整理文献、整理验方,结合现代医家研究,从病因病机、用药特点等方面,分析总结运用桂枝茯苓丸化裁治疗血瘀型功能性肛门直肠痛的诊疗思路,并列举验案加以佐证。结果功能性肛门直肠痛始于气机升降功能的紊乱,血瘀是该病最终趋势,活血化瘀是中医辨治功能性肛门直肠痛的核心方法。结论桂枝茯苓丸在临床中多用于治疗妇科相关疾病,以异病同治创新性地将其引入血瘀型功能性肛门直肠痛的治疗中,临证经验提示疗效显著,为功能性肛门直肠痛的临床诊治提供了新的思路。

异地就医直接结算、待遇可携带性与人口流动适应性研究

在人口大规模流动常态化的社会背景下,异地就医直接结算作为提升医保公共服务效能的政策创新,满足流动人口就医需求的同时也充当着适应人口流动的重要保障机制。本文选取中国健康与养老追踪调查数据,采用Logit模型、PSM模型及中介效应模型对我国异地就医直接结算的人口流动适应性及作用机制进行实证评估。研究发现,随着医保异地就医直接结算开展范围的扩大,一定程度上打破了传统医保的“枷锁”效应,更加适应人口流动。机制分析表明,异地就医直接结算政策通过增强医保待遇可携带性适应人口流动,具体表现为减轻异地就医人员的间接医疗成本、缩短其异地往返的通勤距离和减少垫资成本。医保异地就医直接结算对健康状况好、45岁以下及60岁以上、工作类型为个体或私营、收入较高者等群体的流动具有更好的适应效果。

公共教育扩张政策与教育收益率的城乡差异

基于2019年中国家庭收入调查数据,通过教育收益率的因果性和异质性测量,实证评估了公共教育扩张政策的个体增收效应和收入分配效应。研究结果如下:(1)利用描述性统计法分析发现,公共教育扩张政策对城镇劳动力受教育程度的提升作用高于农村,因而教育功能具有“城市偏向型”的特征;(2)利用工具变量法纠正内生性问题后,发现公共教育扩张政策对非农户籍具有更强的个体增收效应,农村劳动力的教育收益率高于城镇,大学教育收益率高于义务教育阶段,揭示了公共教育扩张政策的个体增收效应具有“农村导向型”的特征;(3)利用无条件分位数回归及其处理效应模型发现,义务教育改革和高校扩招具有缩小城乡劳动力组内工资收入差距的收入分配功能。

基于网络药理学与分子对接技术探讨半夏厚朴汤“异病同治”胃食管反流病和慢性咽炎的作用机制

目的 基于中医学“异病同治”理论,运用网络药理学与分子对接技术探究半夏厚朴汤治疗胃食管反流病(GERD)和慢性咽炎的作用机制。方法 通过中药系统药理学数据库与分析平台、本草组鉴数据库、中医药百科全书数据库检索半夏厚朴汤活性成分及潜在靶点;通过GeneCards、TTD和OMIM数据库获得GERD和慢性咽炎相关靶点;通过Venny平台筛选药物与两种疾病的共同靶点;通过Cytoscape 3.9.1软件构建“药物-活性成分-共同靶点-疾病”网络,以展示其交互作用关系;通过STRING平台构建共同靶点PPI网络;通过Metascape平台对共同靶点进行GO功能及KEGG通路富集分析;运用Schr9dinger Suite对关键靶点和所有活性成分进行分子对接,验证潜在作用靶点与药物成分的结合能力,并筛选出主要活性成分。结果 共筛选半夏厚朴汤活性成分46个,得到药物靶点223个,共获得GERD疾病靶点2 170个,慢性咽炎疾病靶点402个,筛选得到疾病与药物共有靶点59个;其中核心靶点涉及IL-6、TNF、AKT1、IL-1β、VEGFA等;GO分析显示,共有靶点主要参与细胞群增殖的负调控、细胞转运的正向调控、炎症应答等生物过程;KEGG富集结果显示,共有靶点与癌症通路、JAK-STAT、NF-κB等信号通路相关。分子对接结果显示,核心蛋白与大多数活性成分存在结合位点,其中槲皮素、(+)-儿茶素、刺槐苷B、黄芩苷、鞣花酸等成分与核心靶点结合较为稳定,可推测为“异病同治”主要成分。结论 半夏厚朴汤可通过多成分、多靶点、多通路抑制细胞凋亡、减少炎症反应以及调节免疫等发挥对GERD和慢性咽炎的“异病同治”作用。

基于ABAQUS的白砂岩损伤的本构模型的二次开发

ABAQUS有限元分析软件在岩土力学方面的功能很强大,但是ABAQUS软件的材料库中没有白砂岩酸性条件下不同干湿循环处理下的本构模型,因此论文将在ABAQUS的平台上对此模型进行二次开发,将模型编译成UMAT子程序,并对子程序进行验证。通过UMAT二次开发的子程序进行的模拟结果与实际试验的数据对比。

从气血同治探讨慢性气道疾病的异病同治

支气管哮喘和慢性阻塞性肺疾病(简称慢阻肺)同属慢性气道炎症疾病,在病机和治法上有一定的相似性,其都可通过调节气血以恢复肺气宣肃,行使正常生理功能。针对肺的生理功能和气血的关系,探讨支气管哮喘和慢阻肺的共同病机:支气管哮喘的基本病机是痰伏于肺,外邪引动,痰气互结,肺失宣降,并可兼有瘀血阻络之象;慢阻肺的病机以久病肺虚为本,加之痰浊、水饮、瘀血等病理产物,使得肺失宣降,本虚标实的病机随病程持续进展;进而从气血同治角度探讨支气管哮喘和慢阻肺2种慢性气道疾病的异病同治,得出“气血同治,畅通气道”的治疗理念。结合成药的应用,分析以此病机为指导的丹龙口服液组方特点和功效主治,为丹龙口服液异病同治2种气道疾病提供理论依据。

设立产业转型升级示范区对企业融资约束的影响——基于交错双重差分模型

本文以产业转型升级示范区设立作为准自然实验,利用2010-2019年中国A股上市公司数据,采用交错双重差分模型考察了示范区政策对企业融资约束的影响及作用路径,并充分探讨了交错双重差分模型的处理效应异质性。研究发现,示范区设立以后,能够显著缓解辖区内企业的融资约束,并且政策效果具有持续性,上述结论在考虑交错双重差分模型的处理效应异质性以及一系列识别假定检验和稳健性检验后依然成立。机制分析表明,扩大企业融资来源和降低企业经营成本是示范区政策缓解企业融资约束的重要途径。宏观层面加强政府调节,坚持市场导向,进一步扩大开放,能够有效吸引金融机构和投资者参与示范区建设,助力示范区企业资金融通,对缓解示范区企业的融资约束具有积极作用。此外,示范区政策的实施,为企业发展创造了良好的营商环境,吸引大量新企业入驻,激发了企业创新转型发展的内生动力,提升了企业的全要素生产率水平,具有显著的经济效益。本文的结论有助于拓展宏观产业政策与企业行为的研究框架,对进一步完善示范区政策具有重要启示。