Dihydroxy toluene was synthesized from resorcinol in 4 steps:alkylation, methylacylation, Huang Ming Long reaction and dealkylation. In first two steps ethylene dichloride was used as the solvent. This made the two re...Dihydroxy toluene was synthesized from resorcinol in 4 steps:alkylation, methylacylation, Huang Ming Long reaction and dealkylation. In first two steps ethylene dichloride was used as the solvent. This made the two reactions easy and the yields high, and also decreased the amount of DMF used in second step. The third step was a modified Huang Ming Long reaction carried out at more mild condition. The total yield of the title compound was 62%.展开更多
文摘Dihydroxy toluene was synthesized from resorcinol in 4 steps:alkylation, methylacylation, Huang Ming Long reaction and dealkylation. In first two steps ethylene dichloride was used as the solvent. This made the two reactions easy and the yields high, and also decreased the amount of DMF used in second step. The third step was a modified Huang Ming Long reaction carried out at more mild condition. The total yield of the title compound was 62%.
