Objective To compare the different effects of endothelia progenitor cells （ EPCs ） or basic fibroblast growth factor （b-FGF） intromyocardial infusion on cardiac function and neovascularization for dilated cardiomy...Objective To compare the different effects of endothelia progenitor cells （ EPCs ） or basic fibroblast growth factor （b-FGF） intromyocardial infusion on cardiac function and neovascularization for dilated cardiomyopathy（ DCM） rats. Methods Fifty adult female rats received inguinal subcutaneous injections of isoproterenol （ISO, 250 mg/kg） for induction of DCM. Four weeks later, the model rats were randomly divided into EPCs group, b-FGF group and control group. The 2×106 EPCs （ resolved in 100 μL PBS） , 100 μL b-FGF （ lO0 μg/mL ） and 100 μL PBS were evenly transplanted into the myocardium of EPCs group, b-FGF group and control group, respectively. Three months later, echocardiographic examination and regional myocardial blood flow （RMBF） measurement were performed. EPCs were traced by fluorescence in situ hybridization （FISH）. The protein and mRNA expression of b-FGF in each group was measured by ELISA assay and reverse transcription-polymerase chain reaction （ RT-PCR ） . Results Three months after transplantation, sry positive cells were detected only in EPCs group. The cardiac function as well as RMBF was significantly improved in EPCs group compared with b-FGF group or control group. There was higher capillary density in EPCs group. The protein and mRNA expression of b-FGF was stronger than b-FGF group and control group. Conclusion Transplantation of EPCs can improve cardiac function, induce neovascularization and increase RMBF for DCM rats. The treatment with EPCs has better effect than administration of b-FGF alone.展开更多
Poly-scale refinable function with dilation factor a is introduced. The existence of solution of poly-scale refinable equation is investigated. Specially, necessary and sufficient conditions for the orthonormality of ...Poly-scale refinable function with dilation factor a is introduced. The existence of solution of poly-scale refinable equation is investigated. Specially, necessary and sufficient conditions for the orthonormality of solution function Ф of poly-scale refinable equation with integer dilation factor a are established. Some properties of poly-scale refinable function are discussed. Several examples illustrating how to use the method to construct poly-scale refinable function are given.展开更多
In this paper, we extend the generalized multiresolution analysis （GMRA） to higher dimensional spaces. The GMRA is generalized from each ladder space expanded by a different scaling function with positive integer di...In this paper, we extend the generalized multiresolution analysis （GMRA） to higher dimensional spaces. The GMRA is generalized from each ladder space expanded by a different scaling function with positive integer dilation factor m ≥2. The n-d GMRA is discussed in orthogonal and bi-orthogonal cases. Then the optimal m-band wavelets are applied in processing the image datasets of the human body slices. The efficiency and superiority of the algorithm can be seen from the processing results.展开更多
文摘Objective To compare the different effects of endothelia progenitor cells （ EPCs ） or basic fibroblast growth factor （b-FGF） intromyocardial infusion on cardiac function and neovascularization for dilated cardiomyopathy（ DCM） rats. Methods Fifty adult female rats received inguinal subcutaneous injections of isoproterenol （ISO, 250 mg/kg） for induction of DCM. Four weeks later, the model rats were randomly divided into EPCs group, b-FGF group and control group. The 2×106 EPCs （ resolved in 100 μL PBS） , 100 μL b-FGF （ lO0 μg/mL ） and 100 μL PBS were evenly transplanted into the myocardium of EPCs group, b-FGF group and control group, respectively. Three months later, echocardiographic examination and regional myocardial blood flow （RMBF） measurement were performed. EPCs were traced by fluorescence in situ hybridization （FISH）. The protein and mRNA expression of b-FGF in each group was measured by ELISA assay and reverse transcription-polymerase chain reaction （ RT-PCR ） . Results Three months after transplantation, sry positive cells were detected only in EPCs group. The cardiac function as well as RMBF was significantly improved in EPCs group compared with b-FGF group or control group. There was higher capillary density in EPCs group. The protein and mRNA expression of b-FGF was stronger than b-FGF group and control group. Conclusion Transplantation of EPCs can improve cardiac function, induce neovascularization and increase RMBF for DCM rats. The treatment with EPCs has better effect than administration of b-FGF alone.
基金Project supported by the Natural Science Foundation of Guangdong Province (Nos.032038, 05008289, 06105648) the Doctoral Foundation of Guangdong Province (No.04300917)
文摘Poly-scale refinable function with dilation factor a is introduced. The existence of solution of poly-scale refinable equation is investigated. Specially, necessary and sufficient conditions for the orthonormality of solution function Ф of poly-scale refinable equation with integer dilation factor a are established. Some properties of poly-scale refinable function are discussed. Several examples illustrating how to use the method to construct poly-scale refinable function are given.
基金National High-Tech Research and Development Plan(2001AA231031)National Key Basic Research Plan(G1998030608)National Special R&D Plan for Olympic Games(2001BAg04B08).
文摘In this paper, we extend the generalized multiresolution analysis （GMRA） to higher dimensional spaces. The GMRA is generalized from each ladder space expanded by a different scaling function with positive integer dilation factor m ≥2. The n-d GMRA is discussed in orthogonal and bi-orthogonal cases. Then the optimal m-band wavelets are applied in processing the image datasets of the human body slices. The efficiency and superiority of the algorithm can be seen from the processing results.
