Objective:To study the effect of the direct anti-human globulin test on the clinical efficacy of blood transfusion patients.Methods:52 transfused patients were selected for this study,of which 26 cases with positive d...Objective:To study the effect of the direct anti-human globulin test on the clinical efficacy of blood transfusion patients.Methods:52 transfused patients were selected for this study,of which 26 cases with positive direct anti-human globulin tests were included in the positive group,and another 26 cases with negative direct anti-human globulin tests were included in the negative group.The apparent efficacy of the patients in the two groups after blood transfusion was compared.Results:After blood transfusion,the apparent efficacy of the negative group was significantly higher,P<0.05;in the positive group,the proportion of the predominantly multi-antibody group was the highest;after blood transfusion,the post-transfusion apparent efficacy of the simple IgG group was higher than that of the multi-antibody group,P<0.05;comparing the intensity of the different antibodies resulted in the 1+group,and the 3+to 4+groups were significantly lower after blood transfusion,P<0.05.Conclusion:The use of the direct antiglobulin test in transfused patients showed that patients with positive results would have better clinical efficacy.Direct anti-human globulin tests will have an impact on the clinical efficacy of blood transfusion in patients with positive results,so it is very important to carry out a direct anti-human globulin test on blood transfusion patients.展开更多
目的分析在新生儿溶血病(hemolytic disease of the fetus and newborn,HDFN)中血清学检测结果的应用价值。方法选取2019年1月—2022年12月在龙岩市第二医院新生儿科接受治疗的高胆红素血症患儿100例,对其进行抗体释放试验、游离抗体试...目的分析在新生儿溶血病(hemolytic disease of the fetus and newborn,HDFN)中血清学检测结果的应用价值。方法选取2019年1月—2022年12月在龙岩市第二医院新生儿科接受治疗的高胆红素血症患儿100例,对其进行抗体释放试验、游离抗体试验、直接抗人球蛋白试验、不规则抗体筛查、血型鉴定检测,对比产前母体采血送检结果与产后婴儿采血送检结果差异。结果100例患儿中,58例患儿出现母婴血型不合,其中ABO血型系统50例,Rh血型系统8例。ABO血型系统HDFN发生率显著高于Rh血型系统(P<0.05);50例ABO血型系统母婴不合者中,O-A型HDFN发生率显著高于O-B型(P<0.05)。31例HDFN患儿的血清学检测结果中,单独抗体放散试验为阳性的HDFN患儿占比率显著高于其他类型(P<0.05)。产前检测IgG抗A或抗B效价结果与产后采血对比,产前检测准确率为90.32%。结论血清学检测结果在HDFN诊断中具有一定的辅助价值,在1周内检测阳性率最高。展开更多
目的探讨MAP洗涤红细胞(MAP washes the red blood cells,Map WBC)及生理盐水混悬洗涤红细胞(normal saline mixed with red blood cells,WBC)对直接抗人球蛋白试验(direct antiglobulin test,DAT)阳性患者输血治疗的疗效分析。方法选择...目的探讨MAP洗涤红细胞(MAP washes the red blood cells,Map WBC)及生理盐水混悬洗涤红细胞(normal saline mixed with red blood cells,WBC)对直接抗人球蛋白试验(direct antiglobulin test,DAT)阳性患者输血治疗的疗效分析。方法选择2020年1月至2021年12月本院207例直接抗人球蛋白试验阳性患者,分为MAP组(n=93)和盐水组(n=114),MAP组输注MAP洗涤红细胞治疗,盐水组输注生理盐水混悬洗涤红细胞治疗,通过检测血红蛋白(hemoglobin,HGB)和胆红素(total bilirubin,TBIL)实验室指标观察两组患者的输血疗效,同时对输血不良反应进行观察。结果对两组患者输血前后各指标变化程度进行比较,组内HGB和TBIL明显升高,差异有统计学意义(P<0.05),组间HGB和TBIL变化不明显,差异无统计学意义(P>0.05),且两组输血均无不良反应发生。结论DAT阳性患者输注两种洗涤红细胞均安全有效,但MAP洗涤红细胞由于保存时间长,更能满足临床急诊需求。展开更多
文摘Objective:To study the effect of the direct anti-human globulin test on the clinical efficacy of blood transfusion patients.Methods:52 transfused patients were selected for this study,of which 26 cases with positive direct anti-human globulin tests were included in the positive group,and another 26 cases with negative direct anti-human globulin tests were included in the negative group.The apparent efficacy of the patients in the two groups after blood transfusion was compared.Results:After blood transfusion,the apparent efficacy of the negative group was significantly higher,P<0.05;in the positive group,the proportion of the predominantly multi-antibody group was the highest;after blood transfusion,the post-transfusion apparent efficacy of the simple IgG group was higher than that of the multi-antibody group,P<0.05;comparing the intensity of the different antibodies resulted in the 1+group,and the 3+to 4+groups were significantly lower after blood transfusion,P<0.05.Conclusion:The use of the direct antiglobulin test in transfused patients showed that patients with positive results would have better clinical efficacy.Direct anti-human globulin tests will have an impact on the clinical efficacy of blood transfusion in patients with positive results,so it is very important to carry out a direct anti-human globulin test on blood transfusion patients.
文摘目的分析在新生儿溶血病(hemolytic disease of the fetus and newborn,HDFN)中血清学检测结果的应用价值。方法选取2019年1月—2022年12月在龙岩市第二医院新生儿科接受治疗的高胆红素血症患儿100例,对其进行抗体释放试验、游离抗体试验、直接抗人球蛋白试验、不规则抗体筛查、血型鉴定检测,对比产前母体采血送检结果与产后婴儿采血送检结果差异。结果100例患儿中,58例患儿出现母婴血型不合,其中ABO血型系统50例,Rh血型系统8例。ABO血型系统HDFN发生率显著高于Rh血型系统(P<0.05);50例ABO血型系统母婴不合者中,O-A型HDFN发生率显著高于O-B型(P<0.05)。31例HDFN患儿的血清学检测结果中,单独抗体放散试验为阳性的HDFN患儿占比率显著高于其他类型(P<0.05)。产前检测IgG抗A或抗B效价结果与产后采血对比,产前检测准确率为90.32%。结论血清学检测结果在HDFN诊断中具有一定的辅助价值,在1周内检测阳性率最高。
文摘目的探讨MAP洗涤红细胞(MAP washes the red blood cells,Map WBC)及生理盐水混悬洗涤红细胞(normal saline mixed with red blood cells,WBC)对直接抗人球蛋白试验(direct antiglobulin test,DAT)阳性患者输血治疗的疗效分析。方法选择2020年1月至2021年12月本院207例直接抗人球蛋白试验阳性患者,分为MAP组(n=93)和盐水组(n=114),MAP组输注MAP洗涤红细胞治疗,盐水组输注生理盐水混悬洗涤红细胞治疗,通过检测血红蛋白(hemoglobin,HGB)和胆红素(total bilirubin,TBIL)实验室指标观察两组患者的输血疗效,同时对输血不良反应进行观察。结果对两组患者输血前后各指标变化程度进行比较,组内HGB和TBIL明显升高,差异有统计学意义(P<0.05),组间HGB和TBIL变化不明显,差异无统计学意义(P>0.05),且两组输血均无不良反应发生。结论DAT阳性患者输注两种洗涤红细胞均安全有效,但MAP洗涤红细胞由于保存时间长,更能满足临床急诊需求。
