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Chaos Synchronization in Discrete-Time Dynamical Systems with Application in Population Dynamics
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作者 Tahmineh Azizi Gabriel Kerr 《Journal of Applied Mathematics and Physics》 2020年第3期406-423,共18页
Study of chaotic synchronization as a fundamental phenomenon in the nonlinear dynamical systems theory has been recently raised many interests in science, engineering, and technology. In this paper, we develop a new m... Study of chaotic synchronization as a fundamental phenomenon in the nonlinear dynamical systems theory has been recently raised many interests in science, engineering, and technology. In this paper, we develop a new mathematical framework in study of chaotic synchronization of discrete-time dynamical systems. In the novel drive-response discrete-time dynamical system which has been coupled using convex link function, we introduce a synchronization threshold which passes that makes the drive-response system lose complete coupling and synchronized behaviors. We provide the application of this type of coupling in synchronized cycles of well-known Ricker model. This model displays a rich cascade of complex dynamics from stable fixed point and cascade of period-doubling bifurcation to chaos. We also numerically verify the effectiveness of the proposed scheme and demonstrate how this type of coupling makes this chaotic system and its corresponding coupled system starting from different initial conditions, quickly get synchronized. 展开更多
关键词 Chaos SYNCHRONIZATION SYNCHRONIZATION Threshold PERIOD-DOUBLING BIFURCATION CONVEX Link Function Nonlinear dynamics
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Stabilization of Discrete-Time Dynamical Systems Under Event-Triggered Impulsive Control with and Without Time-Delays 被引量:4
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作者 LIU Bin HILL David John +1 位作者 ZHANG Changfan SUN Zhijie 《Journal of Systems Science & Complexity》 SCIE EI CSCD 2018年第1期130-146,共17页
This paper investigates the issue of stabilization for discrete-time dynamical systems(DDS)by event-triggered impulsive control(ETIC). Based on some relatively simple threshold constants, three levels of event con... This paper investigates the issue of stabilization for discrete-time dynamical systems(DDS)by event-triggered impulsive control(ETIC). Based on some relatively simple threshold constants, three levels of event conditions are set and thus the ETIC scheme is designed. Three cases for ETIC with and without time-delays and data dropouts are studied respectively, and the criteria on exponential stability are derived for the controlled DDS. The stabilization in the form of exponential stability is achieved for DDS under the designed ETIC with or without time-delays. And in the case of the ETIC data dropouts, the conditions of exponential stabilization are derived for DDS and the maximal allowable dropout rates for ETIC are estimated. Finally, one example with numerical simulations is worked out for illustration. 展开更多
关键词 Data dropout discrete-time dynamical systems event-triggered control exponential stability impulsive control stabilization time-delay
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Adaptive Optimal Discrete-Time Output-Feedback Using an Internal Model Principle and Adaptive Dynamic Programming 被引量:1
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作者 Zhongyang Wang Youqing Wang Zdzisław Kowalczuk 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第1期131-140,共10页
In order to address the output feedback issue for linear discrete-time systems, this work suggests a brand-new adaptive dynamic programming(ADP) technique based on the internal model principle(IMP). The proposed metho... In order to address the output feedback issue for linear discrete-time systems, this work suggests a brand-new adaptive dynamic programming(ADP) technique based on the internal model principle(IMP). The proposed method, termed as IMP-ADP, does not require complete state feedback-merely the measurement of input and output data. More specifically, based on the IMP, the output control problem can first be converted into a stabilization problem. We then design an observer to reproduce the full state of the system by measuring the inputs and outputs. Moreover, this technique includes both a policy iteration algorithm and a value iteration algorithm to determine the optimal feedback gain without using a dynamic system model. It is important that with this concept one does not need to solve the regulator equation. Finally, this control method was tested on an inverter system of grid-connected LCLs to demonstrate that the proposed method provides the desired performance in terms of both tracking and disturbance rejection. 展开更多
关键词 Adaptive dynamic programming(ADP) internal model principle(IMP) output feedback problem policy iteration(PI) value iteration(VI)
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Stability analysis of synchronization in discrete-time complex dynamical networks 被引量:1
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作者 邵春 顾亚琴 傅新楚 《Journal of Shanghai University(English Edition)》 CAS 2007年第2期121-125,共5页
In this paper, by using both the linear stability analysis and Lyapunov function approach, some conditions for stabilizing synchronization behavior in a discrete-time complex dynamical network were derived. These cond... In this paper, by using both the linear stability analysis and Lyapunov function approach, some conditions for stabilizing synchronization behavior in a discrete-time complex dynamical network were derived. These conditions were determined by the coupling strength and the eigenvalues of coupling configuration matrix. Furthermore, some explicit results were obtained when the coupling map between the nodes is equal to the dynamics function of the network, which implies that the product of the coupling strength and the eigenvalues is bounded. 展开更多
关键词 discrete-time complex network SYNCHRONIZATION STABILITY
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Discrete-time Markov-based dynamic control approach for compressed sampling 被引量:1
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作者 安春燕 纪红 +1 位作者 李屹 张晓亮 《Journal of Southeast University(English Edition)》 EI CAS 2012年第3期287-291,共5页
To solve the problem that the signal sparsity level is time-varying and not known as a priori in most cases,a signal sparsity level prediction and optimal sampling rate determination scheme is proposed.The discrete-ti... To solve the problem that the signal sparsity level is time-varying and not known as a priori in most cases,a signal sparsity level prediction and optimal sampling rate determination scheme is proposed.The discrete-time Markov chain is used to model the signal sparsity level and analyze the transition between different states.According to the current state,the signal sparsity level state in the next sampling period and its probability are predicted.Furthermore,based on the prediction results,a dynamic control approach is proposed to find out the optimal sampling rate with the aim of maximizing the expected reward which considers both the energy consumption and the recovery accuracy.The proposed approach can balance the tradeoff between the energy consumption and the recovery accuracy.Simulation results show that the proposed dynamic control approach can significantly improve the sampling performance compared with the existing approach. 展开更多
关键词 compressed sampling signal sparsity level prediction discrete-time Markov chain
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Superiority of a Convolutional Neural Network Model over Dynamical Models in Predicting Central Pacific ENSO 被引量:2
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作者 Tingyu WANG Ping HUANG 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第1期141-154,共14页
The application of deep learning is fast developing in climate prediction,in which El Ni?o–Southern Oscillation(ENSO),as the most dominant disaster-causing climate event,is a key target.Previous studies have shown th... The application of deep learning is fast developing in climate prediction,in which El Ni?o–Southern Oscillation(ENSO),as the most dominant disaster-causing climate event,is a key target.Previous studies have shown that deep learning methods possess a certain level of superiority in predicting ENSO indices.The present study develops a deep learning model for predicting the spatial pattern of sea surface temperature anomalies(SSTAs)in the equatorial Pacific by training a convolutional neural network(CNN)model with historical simulations from CMIP6 models.Compared with dynamical models,the CNN model has higher skill in predicting the SSTAs in the equatorial western-central Pacific,but not in the eastern Pacific.The CNN model can successfully capture the small-scale precursors in the initial SSTAs for the development of central Pacific ENSO to distinguish the spatial mode up to a lead time of seven months.A fusion model combining the predictions of the CNN model and the dynamical models achieves higher skill than each of them for both central and eastern Pacific ENSO. 展开更多
关键词 ENSO diversity deep learning ENSO prediction dynamical forecast system
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Dynamically triggered seismicity on a tectonic scale:A review 被引量:1
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作者 Chengzhi Qi Mingyang Wang +2 位作者 Gevorg Kocharyan Artem Kunitskikh Zefan Wang 《Deep Underground Science and Engineering》 2024年第1期1-24,共24页
Earthquakes triggered by dynamic disturbances have been confirmed by numerous observations and experiments.In the past several decades,earthquake triggering has attracted increasing attention of scholars in relation t... Earthquakes triggered by dynamic disturbances have been confirmed by numerous observations and experiments.In the past several decades,earthquake triggering has attracted increasing attention of scholars in relation to exploring the mechanism of earthquake triggering,earthquake prediction,and the desire to use the mechanism of earthquake triggering to reduce,prevent,or trigger earthquakes.Natural earthquakes and large‐scale explosions are the most common sources of dynamic disturbances that trigger earthquakes.In the past several decades,some models have been developed,including static,dynamic,quasi‐static,and other models.Some reviews have been published,but explosiontriggered seismicity was not included.In recent years,some new results on earthquake triggering have emerged.Therefore,this paper presents a new review to reflect the new results and include the content of explosion‐triggered earthquakes for the reference of scholars in this area.Instead of a complete review of the relevant literature,this paper primarily focuses on the main aspects of dynamic earthquake triggering on a tectonic scale and makes some suggestions on issues that need to be resolved in this area in the future. 展开更多
关键词 dynamic disturbances dynamic models problems for future research quasi‐static models static models triggered seismicity
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Influencer identification of dynamical networks based on an information entropy dimension reduction method
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作者 段东立 纪思源 袁紫薇 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第4期375-384,共10页
Identifying critical nodes or sets in large-scale networks is a fundamental scientific problem and one of the key research directions in the fields of data mining and network science when implementing network attacks,... Identifying critical nodes or sets in large-scale networks is a fundamental scientific problem and one of the key research directions in the fields of data mining and network science when implementing network attacks, defense, repair and control.Traditional methods usually begin from the centrality, node location or the impact on the largest connected component after node destruction, mainly based on the network structure.However, these algorithms do not consider network state changes.We applied a model that combines a random connectivity matrix and minimal low-dimensional structures to represent network connectivity.By using mean field theory and information entropy to calculate node activity,we calculated the overlap between the random parts and fixed low-dimensional parts to quantify the influence of node impact on network state changes and ranked them by importance.We applied this algorithm and the proposed importance algorithm to the overall analysis and stratified analysis of the C.elegans neural network.We observed a change in the critical entropy of the network state and by utilizing the proposed method we can calculate the nodes that indirectly affect muscle cells through neural layers. 展开更多
关键词 dynamical networks network influencer low-dimensional dynamics network disintegration
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Exponential Synchronization of Delayed Stochastic Complex Dynamical Networks via Hybrid Impulsive Control
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作者 Yao Cui Pei Cheng Xiaohua Ge 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第3期785-787,共3页
Dear Editor,This letter addresses the synchronization problem of a class of delayed stochastic complex dynamical networks consisting of multiple drive and response nodes.The aim is to achieve mean square exponential s... Dear Editor,This letter addresses the synchronization problem of a class of delayed stochastic complex dynamical networks consisting of multiple drive and response nodes.The aim is to achieve mean square exponential synchronization for the drive-response nodes despite the simultaneous presence of time delays and stochastic noises in node dynamics. 展开更多
关键词 dynamICS STOCHASTIC LETTER
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Target layer state estimation in multi-layer complex dynamical networks considering nonlinear node dynamics
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作者 吴亚勇 王欣伟 蒋国平 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第4期245-252,共8页
In many engineering networks, only a part of target state variables are required to be estimated.On the other hand,multi-layer complex network exists widely in practical situations.In this paper, the state estimation ... In many engineering networks, only a part of target state variables are required to be estimated.On the other hand,multi-layer complex network exists widely in practical situations.In this paper, the state estimation of target state variables in multi-layer complex dynamical networks with nonlinear node dynamics is studied.A suitable functional state observer is constructed with the limited measurement.The parameters of the designed functional observer are obtained from the algebraic method and the stability of the functional observer is proven by the Lyapunov theorem.Some necessary conditions that need to be satisfied for the design of the functional state observer are obtained.Different from previous studies, in the multi-layer complex dynamical network with nonlinear node dynamics, the proposed method can estimate the state of target variables on some layers directly instead of estimating all the individual states.Thus, it can greatly reduce the placement of observers and computational cost.Numerical simulations with the three-layer complex dynamical network composed of three-dimensional nonlinear dynamical nodes are developed to verify the effectiveness of the method. 展开更多
关键词 multi-layer complex dynamical network nonlinear node dynamics target state estimation functional state observer
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Dynamical analysis,control,boundedness,and prediction for a fractional-order financial risk system
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作者 Kehao Yang Song Zheng +4 位作者 Tianhu Yu Aceng Sambas Muhamad Deni Johansyah Hassan Saberi-Nik Mohamad Afendee Mohamed 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第11期223-235,共13页
This paper delves into the dynamical analysis,chaos control,Mittag–Leffler boundedness(MLB),and forecasting a fractional-order financial risk(FOFR)system through an absolute function term.To this end,the FOFR system ... This paper delves into the dynamical analysis,chaos control,Mittag–Leffler boundedness(MLB),and forecasting a fractional-order financial risk(FOFR)system through an absolute function term.To this end,the FOFR system is first proposed,and the adomian decomposition method(ADM)is employed to resolve this fractional-order system.The stability of equilibrium points and the corresponding control schemes are assessed,and several classical tools such as Lyapunov exponents(LE),bifurcation diagrams,complexity analysis(CA),and 0–1 test are further extended to analyze the dynamical behaviors of FOFR.Then the global Mittag–Leffler attractive set(MLAS)and Mittag–Leffler positive invariant set(MLPIS)for the proposed financial risk(FR)system are discussed.Finally,a proficient reservoir-computing(RC)method is applied to forecast the temporal evolution of the complex dynamics for the proposed system,and some simulations are carried out to show the effectiveness and feasibility of the present scheme. 展开更多
关键词 FOFR system dynamical analysis CONTROL BOUNDEDNESS forecasting
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Dynamical localization in a non-Hermitian Floquet synthetic system
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作者 可汗 张嘉明 +1 位作者 霍良 赵文垒 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第5期147-151,共5页
We investigate the non-Hermitian effects on quantum diffusion in a kicked rotor model where the complex kicking potential is quasi-periodically modulated in the time domain.The synthetic space with arbitrary dimension... We investigate the non-Hermitian effects on quantum diffusion in a kicked rotor model where the complex kicking potential is quasi-periodically modulated in the time domain.The synthetic space with arbitrary dimension can be created by incorporating incommensurate frequencies in the quasi-periodical modulation.In the Hermitian case,strong kicking induces the chaotic diffusion in the four-dimension momentum space characterized by linear growth of mean energy.We find that the quantum coherence in deep non-Hermitian regime can effectively suppress the chaotic diffusion and hence result in the emergence of dynamical localization.Moreover,the extent of dynamical localization is dramatically enhanced by increasing the non-Hermitian parameter.Interestingly,the quasi-energies become complex when the non-Hermitian parameter exceeds a certain threshold value.The quantum state will finally evolve to a quasi-eigenstate for which the imaginary part of its quasi-energy is large most.The exponential localization length decreases with the increase of the non-Hermitian parameter,unveiling the underlying mechanism of the enhancement of the dynamical localization by nonHermiticity. 展开更多
关键词 Floquet system non-Hermitian physics dynamical localization
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Theory and practice for assessing structural integrity and dynamical integrity of high-speed trains
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作者 Weihua Zhang Yuanchen Zeng +1 位作者 Dongli Song Zhiwei Wang 《Railway Sciences》 2024年第2期113-127,共15页
Purpose–The safety and reliability of high-speed trains rely on the structural integrity of their components and the dynamic performance of the entire vehicle system.This paper aims to define and substantiate the ass... Purpose–The safety and reliability of high-speed trains rely on the structural integrity of their components and the dynamic performance of the entire vehicle system.This paper aims to define and substantiate the assessment of the structural integrity and dynamical integrity of high-speed trains in both theory and practice.The key principles and approacheswill be proposed,and their applications to high-speed trains in Chinawill be presented.Design/methodology/approach–First,the structural integrity and dynamical integrity of high-speed trains are defined,and their relationship is introduced.Then,the principles for assessing the structural integrity of structural and dynamical components are presented and practical examples of gearboxes and dampers are provided.Finally,the principles and approaches for assessing the dynamical integrity of highspeed trains are presented and a novel operational assessment method is further presented.Findings–Vehicle system dynamics is the core of the proposed framework that provides the loads and vibrations on train components and the dynamic performance of the entire vehicle system.For assessing the structural integrity of structural components,an open-loop analysis considering both normal and abnormal vehicle conditions is needed.For assessing the structural integrity of dynamical components,a closed-loop analysis involving the influence of wear and degradation on vehicle system dynamics is needed.The analysis of vehicle system dynamics should follow the principles of complete objects,conditions and indices.Numerical,experimental and operational approaches should be combined to achieve effective assessments.Originality/value–The practical applications demonstrate that assessing the structural integrity and dynamical integrity of high-speed trains can support better control of critical defects,better lifespan management of train components and better maintenance decision-making for high-speed trains. 展开更多
关键词 Structural integrity dynamical integrity Vehicle system dynamics High-speed trains BOGIE Integrity assessment FATIGUE
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Spontaneous Recovery in Directed Dynamical Networks
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作者 Xueming Liu Xian Yan H.Eugene Stanley 《Engineering》 SCIE EI CAS CSCD 2024年第6期208-214,共7页
Complex networked systems,which range from biological systems in the natural world to infrastructure systems in the human-made world,can exhibit spontaneous recovery after a failure;for example,a brain may spontaneous... Complex networked systems,which range from biological systems in the natural world to infrastructure systems in the human-made world,can exhibit spontaneous recovery after a failure;for example,a brain may spontaneously return to normal after a seizure,and traffic flow can become smooth again after a jam.Previous studies on the spontaneous recovery of dynamical networks have been limited to undirected networks.However,most real-world networks are directed.To fill this gap,we build a model in which nodes may alternately fail and recover,and we develop a theoretical tool to analyze the recovery properties of directed dynamical networks.We find that the tool can accurately predict the final fraction of active nodes,and the prediction accuracy decreases as the fraction of bidirectional links in the network increases,which emphasizes the importance of directionality in network dynamics.Due to different initial states,directed dynamical networks may show alternative stable states under the same control parameter,exhibiting hysteresis behavior.In addition,for networks with finite sizes,the fraction of active nodes may jump back and forth between high and low states,mimicking repetitive failure-recovery processes.These findings could help clarify the system recovery mechanism and enable better design of networked systems with high resilience. 展开更多
关键词 Network resilience Directed dynamical networks Spontaneous recovery
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Structure and dynamical properties during solidification of liquid aluminum induced by cooling and compression
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作者 吴旻 杨永琪 王垚 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第7期476-481,共6页
The structural transformation from a liquid into a crystalline solid is an important subject in condensed matter physics and materials science. In the present study, first-principles molecular dynamics calculations ar... The structural transformation from a liquid into a crystalline solid is an important subject in condensed matter physics and materials science. In the present study, first-principles molecular dynamics calculations are performed to investigate the structure and properties of aluminum during the solidification which is induced by cooling and compression. In the cooling process and compression process, it is found that the icosahedral short-range order is initially enhanced and then begin to decay, the face-centered cubic short-range order eventually becomes dominant before it transforms into a crystalline solid. 展开更多
关键词 first-principles method molecular dynamics short-range order liquid aluminum
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A Neural-network-based Alternative Scheme to Include Nonhydrostatic Processes in an Atmospheric Dynamical Core
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作者 Yang XIA Bin WANG +13 位作者 Lijuan LI Li LIU Jianghao LI Li DONG Shiming XU Yiyuan LI Wenwen XIA Wenyu HUANG Juanjuan LIU Yong WANG Hongbo LIU Ye PU Yujun HE Kun XIA 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第6期1083-1099,I0002,I0003,共19页
Here,a nonhydrostatic alternative scheme(NAS)is proposed for the grey zone where the nonhydrostatic impact on the atmosphere is evident but not large enough to justify the necessity to include an implicit nonhydrostat... Here,a nonhydrostatic alternative scheme(NAS)is proposed for the grey zone where the nonhydrostatic impact on the atmosphere is evident but not large enough to justify the necessity to include an implicit nonhydrostatic solver in an atmospheric dynamical core.The NAS is designed to replace this solver,which can be incorporated into any hydrostatic models so that existing well-developed hydrostatic models can effectively serve for a longer time.Recent advances in machine learning(ML)provide a potential tool for capturing the main complicated nonlinear-nonhydrostatic relationship.In this study,an ML approach called a neural network(NN)was adopted to select leading input features and develop the NAS.The NNs were trained and evaluated with 12-day simulation results of dry baroclinic-wave tests by the Weather Research and Forecasting(WRF)model.The forward time difference of the nonhydrostatic tendency was used as the target variable,and the five selected features were the nonhydrostatic tendency at the last time step,and four hydrostatic variables at the current step including geopotential height,pressure in two different forms,and potential temperature,respectively.Finally,a practical NAS was developed with these features and trained layer by layer at a 20-km horizontal resolution,which can accurately reproduce the temporal variation and vertical distribution of the nonhydrostatic tendency.Corrected by the NN-based NAS,the improved hydrostatic solver at different horizontal resolutions can run stably for at least one month and effectively reduce most of the nonhydrostatic errors in terms of system bias,anomaly root-mean-square error,and the error of the wave spatial pattern,which proves the feasibility and superiority of this scheme. 展开更多
关键词 neural network nonhydrostatic alternative scheme atmospheric model dynamical core
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Enhanced measurement precision with continuous interrogation during dynamical decoupling
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作者 张军 杜鹏 +3 位作者 敬雷 徐鹏 尤力 张文献 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第3期88-94,共7页
Dynamical decoupling(DD)is normally ineffective when applied to DC measurement.In its straightforward implementation,DD nulls out DC signal as well while suppressing noise.This work proposes a phase relay method that ... Dynamical decoupling(DD)is normally ineffective when applied to DC measurement.In its straightforward implementation,DD nulls out DC signal as well while suppressing noise.This work proposes a phase relay method that is capable of continuously interrogating the DC signal over many DD cycles.We illustrate its efficacy when applied to the measurement of a weak DC magnetic field with an atomic spinor Bose-Einstein condensate.Sensitivities approaching standard quantum limit or Heisenberg limit are potentially realizable for a coherent spin state or a squeezed spin state of 10000 atoms,respectively,while ambient laboratory level noise is suppressed by DD.Our work offers a practical approach to mitigate the limitations of DD to DC measurement and would find other applications for resorting coherence in quantum sensing and quantum information processing research. 展开更多
关键词 quantum sensing continuous interrogation quantum magnetometer dynamical decoupling Heisenberg limit
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A Unique Modelling Strategy to Dynamically Simulate the Performance of a Lobe Pump for Industrial Applications
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作者 Deepak Kumar Kanungo Rabiranjan Murmu Harekrushna Sutar 《Advances in Chemical Engineering and Science》 CAS 2024年第2期57-73,共17页
The performance of a newly designed tri-lobe industrial lobe pump of high capacity is simulated by using commercial CFD solver Ansys Fluent. A combination of user-defined-functions and meshing strategies is employed t... The performance of a newly designed tri-lobe industrial lobe pump of high capacity is simulated by using commercial CFD solver Ansys Fluent. A combination of user-defined-functions and meshing strategies is employed to capture the rotation of the lobes. The numerical model is validated by comparing the simulated results with the literature values. The processes of suction, displacement, compression and exhaust are accurately captured in the transient simulation. The fluid pressure value remains in the range of inlet pressure value till the processes of suction and displacement are over. The instantaneous process of compression is accurately captured in the simulation. The movement of a particular working chamber is traced along the gradual degree of lobe’s rotation. At five different degrees of lobe’s rotation, pressure contour plots are reported which clearly shows the pressure values inside the working chamber. Each pressure value inside the working chamber conforms to the particular process in which the working chamber is operating. Finally, the power requirement at the shaft of rotation is estimated from the simulated values. The estimated value of power requirement is 3.61 BHP FHP whereas the same calculated theoretically is 3 BHP FHP. The discrepancy is attributed to the assumption of symmetry of blower along the thickness. 展开更多
关键词 CFD Lobe Pump Moving dynamic Mesh Pressure Fluctuation Transient Simulation
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Computing large deviation prefactors of stochastic dynamical systems based on machine learning
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作者 李扬 袁胜兰 +1 位作者 陆凌宏志 刘先斌 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第4期364-373,共10页
We present a large deviation theory that characterizes the exponential estimate for rare events in stochastic dynamical systems in the limit of weak noise.We aim to consider a next-to-leading-order approximation for m... We present a large deviation theory that characterizes the exponential estimate for rare events in stochastic dynamical systems in the limit of weak noise.We aim to consider a next-to-leading-order approximation for more accurate calculation of the mean exit time by computing large deviation prefactors with the aid of machine learning.More specifically,we design a neural network framework to compute quasipotential,most probable paths and prefactors based on the orthogonal decomposition of a vector field.We corroborate the higher effectiveness and accuracy of our algorithm with two toy models.Numerical experiments demonstrate its powerful functionality in exploring the internal mechanism of rare events triggered by weak random fluctuations. 展开更多
关键词 machine learning large deviation prefactors stochastic dynamical systems rare events
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Unveiling structural and dynamical features of chromatin using NMR spectroscopy This article is part of the virtual special issue“Solid-state NMR studies on polymers and biological solids”
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作者 Xiangyan Shi 《Magnetic Resonance Letters》 2024年第4期62-70,共9页
Eukaryotic deoxyribonucleic acid(DNA)is wrapped around histone octamers(HOs)to form nucleosome core particles(NCPs),which in turn interact with linker DNA and linker histones to assemble chromatin fibers with more com... Eukaryotic deoxyribonucleic acid(DNA)is wrapped around histone octamers(HOs)to form nucleosome core particles(NCPs),which in turn interact with linker DNA and linker histones to assemble chromatin fibers with more complex,high-order structures.The molecular properties of chromatin are dynamically regulated by several factors,such as post-translational modifications and effector proteins,to maintain genome stability.In the past two decades,high-resolution techniques have led to many breakthroughs in understanding the molecular mechanisms that govern chromatin regulation.Nuclear magnetic resonance(NMR)has emerged as one of the major techniques in this field,providing new insights into the nucleosomes and nucleosome-protein complexes in different states ranging from soluble form to condensed states.Solution-state NMR has proven valuable in elucidating the conformational dynamics and molecular interactions for histone N-terminal tails,histone core regions and DNA with the combination of specific isotopic labeling.Solid-state NMR,which is not constrained by the high molecular weights of complexes like nucleosomes,has been applied to capture the structural and dynamical characteristics of both flexible tails and rigid histone core regions in nucleosomes and their complexes with effector proteins.Furthermore,the combination of the two techniques allows tracking molecular properties of nucleosomes during phase separation processes,which potentially play essential roles in chromatin regulation.This review summarizes recent advances in NMR studies of chromatin structure and dynamics.It highlighted that NMR revealed unique molecular characteristics for nucleosomes that are often invisible experimentally by other techniques like cryogenic electron microscopy(cryo-EM)and X-ray diffraction(XRD).I envision that,with future ef-forts such as the development of NMR methods and optimization of sample production protocols,solution-state NMR and solid-state NMR will provide invaluable information to expand our understanding of chromatin activity and its regulatory processes. 展开更多
关键词 CHROMATIN Structure dynamics Phase separation Solution-state NMR Solid-state NMR
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