期刊文献+
共找到377篇文章
< 1 2 19 >
每页显示 20 50 100
The Dissemination, Acceptance and Evolution of The Romance of the Three Kingdoms in Japan
1
作者 CHEN Rui-qi LI Jie 《Journal of Literature and Art Studies》 2024年第7期527-540,共14页
As one of the Four Great Masterpieces of China,The Romance of the Three Kingdoms has become a landmark of ancient Chinese literature with vivid and profound character images,ups and downs of politics and war descripti... As one of the Four Great Masterpieces of China,The Romance of the Three Kingdoms has become a landmark of ancient Chinese literature with vivid and profound character images,ups and downs of politics and war descriptions,and appealing historical plots.After being introduced to Japan in the second half of the 17th century,it was spread in Japanese society and was accepted for literary value,social needs and other reasons,then a series of evolutions were produced by combining with local culture,eventually becoming a national culture in Japan.This paper selects the most popular text of The Romance of the Three Kingdoms with 24 chapters and 120 verses in the Wanli period of the Ming Dynasty,and the Japanese translation of The Popular Romance of the Three Kingdoms published by Hunan Wenshan in 1689 as the objects,guided by Ralph Linton’s“Manifestation,Selection,Integration”cultural communication research method,to analyze the dissemination,acceptance and evolution of The Romance of the Three Kingdoms in 17-20 centuries’Japan,which started from the field of literature,then combined with various cultural forms and spread to the civic class,and finally entered politics area and produced a series of evolutions under the influence of Japanese values to become the representative culture of Japan.This paper suggests that in today’s world of frequent cultural exchanges,China should,based on strengthening cultural self-confidence,actively and appropriately select and accept foreign cultures with the attitude of prioritizing our own culture and utilizing foreign culture for our own purposes.The research outcome can provide experience for the current Chinese culture to go to the world with high quality. 展开更多
关键词 The Romance of the Three Kingdoms dissemination ACCEPTANCE EVOLUTION
下载PDF
On the Dissemination and Acceptance of Dongpo Culture in the UK and the US
2
作者 QIU Shicun XU Jinwen 《Sino-US English Teaching》 2024年第7期322-327,共6页
This study delves into the intricate dissemination and acceptance of Dongpo Culture,epitomized by Su Shi,in the UK and the US,aiming to bolster the global recognition of Chinese literary and cultural values and advanc... This study delves into the intricate dissemination and acceptance of Dongpo Culture,epitomized by Su Shi,in the UK and the US,aiming to bolster the global recognition of Chinese literary and cultural values and advance the national strategy of“Going Out”.Su Shi’s multifaceted contributions—spanning literature,philosophy,calligraphy,and art—serve as a pinnacle of Northern Song Dynasty culture.This research evaluates the varied translations,monographs,biographies,journal articles,and doctoral dissertations about Su Shi in these Western nations,using literature analysis,typical analysis,and comparative methods.The findings reveal a robust interest in Su Shi studies in the US,marked by a proliferation of scholarly works and translations across diverse disciplines,such as literature,art,and aesthetics,establishing the US as a leading center for Dongpo Culture studies.Conversely,the UK,despite its early engagement,shows limited scholarly outputs and significant research papers on the subject.By examining Dongpo Culture’s overseas communication path and influence paradigm,this paper seeks to enhance China’s cultural soft power and self-confidence.It underscores the vital role of international cultural exchange in constructing a positive image of China’s national identity,facilitating its peaceful rise,and providing strategic insights for the global promotion of Chinese culture. 展开更多
关键词 Dongpo Culture dissemination and acceptance national image cultural soft power
下载PDF
A Study on the Path of Promoting External Dissemination of Regional Culture with Translation Technology under the Background of New Quality Productivity
3
作者 Juan Zhou 《Journal of Contemporary Educational Research》 2024年第8期26-31,共6页
With the introduction of the concept of new quality productivity characterized by high technology,efficiency,and quality,various industries in China have ignited a high spirit of innovation and development.Against thi... With the introduction of the concept of new quality productivity characterized by high technology,efficiency,and quality,various industries in China have ignited a high spirit of innovation and development.Against this background,this article analyzes the significance and current situation of the external dissemination of regional culture and combines the application of translation technology empowered by new quality productivity to explore a path suitable for the wider,more effective,and higher-quality external dissemination of regional culture.The aim is to provide practical experience for promoting the effective dissemination of regional culture in China to the world and better build a cultural power. 展开更多
关键词 New quality productivity Regional culture External dissemination Translation technology
下载PDF
On the International Dissemination of Zhuang Medicine
4
作者 ZHANG Yan TAO Jien +1 位作者 LIAN Yujie CHEN Yingzhu 《Journalism and Mass Communication》 2024年第4期227-231,共5页
As an important part of Chinese culture,Zhuang medicine has a long history and unique diagnosis and treatment.With the international dissemination of Chinese culture,the international dissemination of Zhuang medicine ... As an important part of Chinese culture,Zhuang medicine has a long history and unique diagnosis and treatment.With the international dissemination of Chinese culture,the international dissemination of Zhuang medicine has become an increasing concern.This paper aims to discuss the status quo,challenges of the international dissemination of Zhuang medicine,then puts forwards corresponding solutions and recommendations,so as to make Zhuang medicine known by the world. 展开更多
关键词 international dissemination Zhuang medicine intercultural communication
下载PDF
SDN-Enabled Content Dissemination Scheme for the Internet of Vehicles
5
作者 Abida Sharif Muhammad Imran Sharif +5 位作者 Muhammad Attique Khan Nisar Ali Abdullah Alqahtani Majed Alhaisoni Ye Jin Kim Byoungchol Chang 《Computers, Materials & Continua》 SCIE EI 2023年第5期2383-2396,共14页
The content-centric networking(CCN)architecture allows access to the content through name,instead of the physical location where the content is stored,which makes it a more robust and flexible content-based architectu... The content-centric networking(CCN)architecture allows access to the content through name,instead of the physical location where the content is stored,which makes it a more robust and flexible content-based architecture.Nevertheless,in CCN,the broadcast nature of vehicles on the Internet of Vehicles(IoV)results in latency and network congestion.The IoVbased content distribution is an emerging concept in which all the vehicles are connected via the internet.Due to the high mobility of vehicles,however,IoV applications have different network requirements that differ from those of many other networks,posing new challenges.Considering this,a novel strategy mediator framework is presented in this paper for managing the network resources efficiently.Software-defined network(SDN)controller is deployed for improving the routing flexibility and facilitating in the interinteroperability of heterogeneous devices within the network.Due to the limited memory of edge devices,the delectable bloom filters are used for caching and storage.Finally,the proposed scheme is compared with the existing variants for validating its effectiveness. 展开更多
关键词 Internet of vehicles(IOV) content dissemination multi mediator data traffic management
下载PDF
The Dissemination of Intangible Cultural Heritage Along Beijing-Hangzhou Canal Based on Encoding/Decoding Theory
6
作者 TAN Hao XIANYU Jing 《Cultural and Religious Studies》 2023年第5期241-245,共5页
The Beijing-Hangzhou Grand Canal carries a wealth of Chinese cultural symbols,showing the lifestyle and wisdom of working people through ages.The preservation and inheritance of its intangible cultural heritage can he... The Beijing-Hangzhou Grand Canal carries a wealth of Chinese cultural symbols,showing the lifestyle and wisdom of working people through ages.The preservation and inheritance of its intangible cultural heritage can help to evoke cultural memories and cultural identification of the Canal and build cultural confidence.This paper applies Stuart Hall’s encoding/decoding theory to analyze the dissemination of intangible heritage tourism culture.On the basis of a practical study of the villages along the Beijing-Hangzhou Grand Canal,this paper analyses the problems in the transmission of its intangible cultural heritage and proposes specific methods to solve them in four processes,encoding,decoding,communication,and secondary encoding,in order to propose references for the transmission of intangible heritage culture at home and abroad. 展开更多
关键词 dissemination ENCODING DECODING intangible cultural heritage
下载PDF
Oral Literature:The Translation and Dissemination of Mulian Baojuan in the English World
7
作者 LIU Yue 《Journal of Philosophy Study》 2023年第3期135-140,共6页
Mulian baojuan,originating from the Sūtra of Ullambana,tells the story of Mulian rescuing his mother from hell.Rostislav Berezkin,David Johnson,and Wilt L.Idema have studied and introduced it.This paper mainly discus... Mulian baojuan,originating from the Sūtra of Ullambana,tells the story of Mulian rescuing his mother from hell.Rostislav Berezkin,David Johnson,and Wilt L.Idema have studied and introduced it.This paper mainly discusses the translation and dissemination of baojuan to sort out and verify its spread in the English world.The translation and dissemination of baojuan have shifted towards its performances,illustrations,and social functions.The study of baojuan has presented a new development trend by breaking the restrictions of the genre of text and through dynamic interactions with novels,dramas,and other forms of literature. 展开更多
关键词 Mulian baojuan TRANSLATION dissemination English world
下载PDF
English Translation of Chinese Traditional Cultural Vocabulary Under the Context of Cultural Dissemination
8
作者 WU Zhexi 《Sino-US English Teaching》 2023年第5期195-198,共4页
The influence of Chinese culture in English-speaking countries is still not as significant as that of Japan and other East Asian countries.Therefore,it is necessary to explore the English translation of vocabulary wit... The influence of Chinese culture in English-speaking countries is still not as significant as that of Japan and other East Asian countries.Therefore,it is necessary to explore the English translation of vocabulary with Chinese elements.Based on the main purpose of cultural dissemination,this article briefly classifies vocabulary with Chinese elements,explores translation strategies for Chinese traditional cultural vocabulary,and summarizes the actual cultural propaganda effects.The article also provides insights and suggestions for subsequent strategy applications. 展开更多
关键词 cultural dissemination traditional cultural vocabulary translation strategies
下载PDF
中国古代槟榔文化的接受与传播
9
作者 冯青 《农业考古》 北大核心 2024年第4期195-201,共7页
作为舶来品的槟榔,在饮食、医药、赋税等方面扮演过重要的角色,具有丰厚的历史文化。梳理文献发现,两汉三国时期,槟榔视作“奇草异木”记载在各种《异物志》中,开始被接受;南北朝时期,槟榔是贵族士宦的“奢侈品”,唐代受佛教平等思想影... 作为舶来品的槟榔,在饮食、医药、赋税等方面扮演过重要的角色,具有丰厚的历史文化。梳理文献发现,两汉三国时期,槟榔视作“奇草异木”记载在各种《异物志》中,开始被接受;南北朝时期,槟榔是贵族士宦的“奢侈品”,唐代受佛教平等思想影响日渐向大众传播,宋代逐渐成为百姓家的“寻常物”。槟榔之所以能被接受与传播,并在海南用于婚俗,是因其本身的物质文化之外,还与其因贵异而用于重要的人际礼仪、文人墨客极力推崇渲染和赋予了槟榔君子品格等精神文化有着莫大的关系。 展开更多
关键词 betel nut culture imported product ACCEPTANCE dissemination
下载PDF
On the Problem of All Equal Positive Odd Number Solutions of the Dissemination of the Ends' Guess 被引量:1
10
作者 刘元宗 《Chinese Quarterly Journal of Mathematics》 CSCD 2000年第2期108-109,共2页
The thesis is concerned with the problem of the dissemination of the Ends’ guess and offers the formula of all equal positive odd number solutions.
关键词 Ends’ guess dissemination all equal positive odd number solutions
下载PDF
Comparison between sepsis-induced coagulopathy and sepsis-associated coagulopathy criteria in identifying sepsis-associated disseminated intravascular coagulation
11
作者 Huixin Zhao Yiming Dong +4 位作者 Sijia Wang Jiayuan Shen Zhenju Song Mingming Xue Mian Shao 《World Journal of Emergency Medicine》 SCIE CAS CSCD 2024年第3期190-196,共7页
BACKGROUND:Disseminated intravascular coagulation(DIC)is associated with increased mortality in sepsis patients.In this study,we aimed to assess the clinical ability of sepsis-induced coagulopathy(SIC)and sepsis-assoc... BACKGROUND:Disseminated intravascular coagulation(DIC)is associated with increased mortality in sepsis patients.In this study,we aimed to assess the clinical ability of sepsis-induced coagulopathy(SIC)and sepsis-associated coagulopathy(SAC)criteria in identifying overt-DIC and preDIC status in sepsis patients.METHODS:Data from 419 sepsis patients were retrospectively collected from July 2018 to December 2022.The performances of the SIC and SAC were assessed to identify overt-DIC on days 1,3,7,or 14.The SIC status or SIC score on day 1,the SAC status or SAC score on day 1,and the sum of the SIC or SAC scores on days 1 and 3 were compared in terms of their ability to identify pre-DIC.The SIC or SAC status on day 1 was evaluated as a pre-DIC indicator for anticoagulant initiation.RESULTS:On day 1,the incidences of coagulopathy according to overt-DIC,SIC and SAC criteria were 11.7%,22.0%and 31.5%,respectively.The specificity of SIC for identifying overt-DIC was significantly higher than that of the SAC criteria from day 1 to day 14(P<0.05).On day 1,the SIC score with a cut-off value>3 had a significantly higher sensitivity(72.00%)and area under the curve(AUC)(0.69)in identifying pre-DIC than did the SIC or SAC status(sensitivity:SIC status 44.00%,SAC status 52.00%;AUC:SIC status 0.62,SAC status 0.61).The sum of the SIC scores on days 1 and 3 had a higher AUC value for identifying the pre-DIC state than that of SAC(0.79 vs.0.69,P<0.001).Favorable effects of anticoagulant therapy were observed in SIC(adjusted hazard ratio[HR]=0.216,95%confidence interval[95%CI]:0.060–0.783,P=0.018)and SAC(adjusted HR=0.146,95%CI:0.041–0.513,P=0.003).CONCLUSION:The SIC and SAC seem to be valuable for predicting overt-DIC.The sum of SIC scores on days 1 and 3 has the potential to help identify pre-DIC. 展开更多
关键词 Sepsis Disseminated intravascular coagulation Sepsis-induced coagulopathy Sepsis-associated coagulopathy
下载PDF
Colorectal cancer and dormant metastases:Put to sleep or destroy?
12
作者 Marina A Senchukova 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第6期2304-2317,共14页
After reading the review by An et al“Biological factors driving colorectal cancer metastasis”,which covers the problem of the metastasis of colorectal cancer(CRC),I had a desire to discuss with readers one of the ex... After reading the review by An et al“Biological factors driving colorectal cancer metastasis”,which covers the problem of the metastasis of colorectal cancer(CRC),I had a desire to discuss with readers one of the exciting problems associated with dormant metastases.Most deaths from CRCs are caused by metastases,which can be detected both at diagnosis of the primary tumor and several years or even decades after treatment.This is because tumor cells that enter the bloodstream can be destroyed by the immune system,cause metastatic growth,or remain dormant for a long time.Dormant tumor cells may not manifest themselves throughout a person’s life or,after some time and under appropriate conditions,may give rise to the growth of metastases.In this editorial,we will discuss the most important features of dormant metastases and the mechanisms of premetastatic niche formation,as well as factors that contribute to the activation of dormant metastases in CRCs.We will pay special attention to the possible mechanisms involved in the formation of circulating tumor cell complexes and the choice of therapeutic strategies that promote the dormancy or destruction of tumor cells in CRCs. 展开更多
关键词 Circulating tumor cells Colorectal cancer Disseminated tumor cells Dormant metastases METASTASES Premetastatic niche
下载PDF
psk1 virulence gene-induced pulmonary and systemic tuberculosis in a young woman with normal immune function:A case report
13
作者 Fan Wu Bin Yang +6 位作者 Yan Xiao Li-Li Ren Hong-Yi Chen Xin-Lan Hu Yan-Yu Pan Yu-Sheng Chen Hong-Ru Li 《World Journal of Clinical Cases》 SCIE 2024年第35期6826-6833,共8页
BACKGROUND Tuberculosis is a chronic infectious disease and an important public health pro-blem.Despite progress in controlling tuberculosis,the incidence of tuberculosis in China is still very high,with 895000 new ca... BACKGROUND Tuberculosis is a chronic infectious disease and an important public health pro-blem.Despite progress in controlling tuberculosis,the incidence of tuberculosis in China is still very high,with 895000 new cases annually.This case report des-cribes the investigation of a case of severe disseminated tuberculosis in a young adult with normal immune function,conducted to ascertain why a Mycobacterium tuberculosis(M.tuberculosis)strain caused such severe disease.CASE SUMMARY A previously healthy 28-year-old woman presented to our hospital with a 1-mo-nth history of fever and fatigue.She was diagnosed with severe disseminated pulmonary tuberculosis,spinal tuberculosis with paravertebral abscesses,and tuberculous meningitis.M.tuberculosis was isolated from bronchoal-veolar lavage fluid.She was treated with standard antituberculous therapy and underwent debridement,bone graft,and internal fixation surgery for spinal tuberculosis.She responded to therapy and regained her ability to walk following the surgery.We analysed the whole-genome sequence of the strain and designated it BLM-A21.Additional M.tuberculosis genomes were selected from the Virulence Factor Database(http://www.mgc.ac.cn/cgi-bin/VFs/genus.cgi?Genus=Mycobacterium)for comparison.An evolutionary tree of the BLM-A21 strain was built using PhyML maximum likelihood software.Further gene analysis revealed that,except for the pks1 gene,BLM-A21 had similar virulence genes to the CDC 1551 and H37Rv strains,which have lower dissemination.CONCLUSION We speculate that the pks1 virulence gene in BLM-A21 may be the key virulence gene responsible for the wide-spread dissemination of M.tuberculosis infection in this previously healthy adult with normal immune function. 展开更多
关键词 Mycobacterium tuberculosis Disseminated tuberculosis Spinal tuberculosis Tuberculous meningitis Virulence gene Whole-genome sequencing Case report
下载PDF
Floristic Diversity, Stand Structure and Plant Life Traits in the Forest-Savanna Mosaic at Ndjole (Centre Cameroon)
14
作者 Djeuguen Vanessa Tchaleu Solefack Marie Caroline Momo +3 位作者 Mateso Aimé Kambale Ndondjeu Charles Tafen Yanick Borel Kamga Victor François Nguetsop 《Open Journal of Ecology》 2024年第4期309-330,共22页
With the aim of assessing floristic diversity, stand structure and vegetation ecology, the present work was carried out in the savanna mosaic forest of the locality of Ndjole (Centre Cameroon). A total of 30 floristic... With the aim of assessing floristic diversity, stand structure and vegetation ecology, the present work was carried out in the savanna mosaic forest of the locality of Ndjole (Centre Cameroon). A total of 30 floristic plots of 40 m × 40 m (1600 m<sup>2</sup>) were delineated in the different ecosystems (forest, forest-savanna contact zone and the savanna). Within each plot, all individuals with a diameter at breast height ≥ 10 cm at 1.30 m were taken into account. ANOVA was used to compare the means of the diversity indices of the different ecosystems, and the DUNCAN test at 5% significance level (XLSTAT 2016) to separate these means. A total of 85 species belonging to 67 genera and 33 families were recorded. That is, 68 species in semi-caducifolia forest, 45 in forest-savanna contact zone and 18 in savanna. Urticaceae, Combretaceae, Apocynaceae, Myristicaceae and Euphorbiaceae are the most diverse families in the forest. On the other hand, in contact zones, the Euphorbiaceae, Fabaceae, Annonaceae and Moraceae families are the most diversified, while in the savannas, the Combretaceae, Fabaceae and Annonaceae families are the most diversified. Shannon’s diversity index values (1.7 to 2.37 bits) reflect low specific diversity;Piélou’s equitability (0.86 to 0.9) shows good distribution of individuals within species. The diametric structure of woody species shows an inverted “J” shape in all plant communities. This indicates a high regeneration potential characterized by a greater number of small trees than large trees. Mesophanerophytes and megaphanerophytes are dominant in forests and forest-savanna contact zones, and microphanerophytes in the savannas. Endozoochory is the main mode of diaspore dissemination. As regards the distribution of phytogeographical types, it shows the overall dominance of Guineo-Congolese species in all plant communities. Our study provides detailed data on forest-savanna floristic and plant life traits in the mosaic and recommends further studies on the impact of environmental parameter variations on the forest encroachment into savanna. 展开更多
关键词 MOSAIC COMMUNITIES dissemination Regeneration Diversity
下载PDF
Clinical and pathological characteristics and expression of related molecules in patients with airway disseminated lung adenocarcinoma
15
作者 Wei Luan Shuai Liu +1 位作者 Kai Zhang Yin-Zai He 《Oncology and Translational Medicine》 2024年第1期30-34,共5页
Objective:Lung adenocarcinoma exhibits diverse genetic and morphological backgrounds,in addition to considerable differences in clinical pathology and molecular biological characteristics.Among these,the phenomenon of... Objective:Lung adenocarcinoma exhibits diverse genetic and morphological backgrounds,in addition to considerable differences in clinical pathology and molecular biological characteristics.Among these,the phenomenon of spread through air space(STAS),a distinct mode of lung cancer infiltration,has rarely been reported.Therefore,this study aimed to explore the relationship between STAS tumor cells and the clinical and molecular characteristics of patients with lung adenocarcinoma,as well as their impact on prognosis.Methods:This study included 147 patients who were diagnosed with lung adenocarcinoma at the Inner Mongolia Autonomous Region Cancer Institute between January 2014 and December 2017.Surgical resection specimens were retrospectively analyzed.Using univariate and multivariate Cox analyses,we assessed the association between STAS and the clinicopathological features and molecular characteristics of patients with lung adenocarcinoma.Furthermore,we investigated the effects on patient prognosis.In addition,we developed a column–line plot prediction model and performed internal validation.Results:Patients with positive STAS had a significantly higher proportion of tumors with a diameter≥2 cm,with infiltration around the pleura,blood vessels,and nerves,and a pathological stage>IIB than in STAS-negative patients(P<0.05).Cox multivariate survival analysis revealed that clinical stage,STAS status,tumor size,and visceral pleural invasion were independent prognostic factors influencing the 5-year progression-free survival in patients with lung adenocarcinoma.The predictive values and P values from the Hosmer-Lemeshow test were 0.8 and 0.2,respectively,indicating no statistical difference.Receiver operating characteristic curve analysis demonstrated areas under the curve of 0.884 and 0.872 for the training and validation groups,respectively.The nomogram model exhibited the best fit with a value of 192.09.Conclusions:Clinical stage,pleural invasion,vascular invasion,peripheral nerve invasion,tumor size,and necrosis are independent prognostic factors for patients with STAS-positive lung adenocarcinoma.The nomogrambased on the clinical stage,pleural invasion,vascular invasion,peripheral nerve invasion,tumor size,and necrosis showed good accuracy,differentiation,and clinical practicality. 展开更多
关键词 Airway dissemination of tumor cells Lung adenocarcinoma Clinicopathological characteristics NOMOGRAM Prognosis prediction model
下载PDF
Hierarchical Media Ethics in the Digital Age: An Analysis of the “Primary School Student Lost Homework in Paris” Incident
16
作者 ZHAO Yifei 《Journalism and Mass Communication》 2024年第3期205-208,共4页
In the digital age,traditional media ethics norms lack sufficient explanatory power and binding force in practice.This paper uses the“Primary School Student Lost Homework in Paris”incident as a case study to explore... In the digital age,traditional media ethics norms lack sufficient explanatory power and binding force in practice.This paper uses the“Primary School Student Lost Homework in Paris”incident as a case study to explore the ethical controversies surrounding the dissemination of this event.By adopting a hierarchical media ethics perspective,the paper dynamically examines the ethical conduct of various communicators,elucidates the ethical responsibilities of each party involved,and reveals the complexity of communication ethics in the digital age. 展开更多
关键词 media ethics information dissemination self-media ethics norms “Primary School Student Lost Homework in Paris”
下载PDF
International Dissemination of TCM Culture under the "Belt and Road" Initiative: Opportunities and Challenges
17
作者 毛和荣 LIU Dian-gang HE Qiang 《海外英语》 2017年第1期168-169,184,共3页
The international dissemination of TCM culture, as a carrier of the implementation of the"Belt and Road"Initiative, is being endowed with greater importance. However, the spread of TCM culture into the world... The international dissemination of TCM culture, as a carrier of the implementation of the"Belt and Road"Initiative, is being endowed with greater importance. However, the spread of TCM culture into the world faces opportunities as well as challenges. To better serve the"Belt and Road"Initiative, measures should be taken to strengthen TCM communication and cooperation in different aspects and build a sound intellectual property protection system. 展开更多
关键词 International dissemination TCM Culture the " Belt and Road " Initiative OPPORTUNITIES Challenges
下载PDF
Molecular mechanisms of peritoneal dissemination in gastric cancer 被引量:20
18
作者 Mitsuro Kanda Yasuhiro Kodera 《World Journal of Gastroenterology》 SCIE CAS 2016年第30期6829-6840,共12页
Peritoneal dissemination represents a devastating form of gastric cancer(GC) progression with a dismal prognosis. There is no effective therapy for this condition. The 5-year survival rate of patients with peritoneal ... Peritoneal dissemination represents a devastating form of gastric cancer(GC) progression with a dismal prognosis. There is no effective therapy for this condition. The 5-year survival rate of patients with peritoneal dissemination is 2%, even including patients with only microscopic free cancer cells without macroscopic peritoneal nodules. The mechanism of peritoneal dissemination of GC involves several steps: detachment of cancer cells from the primary tumor, survival in the free abdominal cavity, attachment to the distant peritoneum, invasion into the subperitoneal space and proliferation with angiogenesis. These steps are not mutually exclusive, and combinations of different molecular mechanisms can occur in each process of peritoneal dissemination. A comprehensive understanding of the molecular events involved in peritoneal dissemination is important and should be systematically pursued. It is crucial to identify novel strategies for the prevention of this condition and for identification of markers of prognosis and the development of molecular-targeted therapies. In this review, we provide an overview of recently published articles addressing the molecular mechanisms of peritoneal dissemination of GC to provide an update on what is currently known in this field and to propose novel promising candidates for use in diagnosis and as therapeutic targets. 展开更多
关键词 GASTRIC cancer PERITONEAL dissemination MICROENVIRONMENT BIOMARKER Molecular target
下载PDF
Prognostic nutritional index is an independent prognostic factor for gastric cancer patients with peritoneal dissemination 被引量:20
19
作者 Runcong Nie Shuqiang Yuan +7 位作者 Shi Chen Xiaojiang Chen Yongming Chen Baoyan Zhu Haibo Qiu Zhiwei Zhou Junsheng Peng Yingbo Chen 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 2016年第6期570-578,共9页
Objective: The predictive and prognostic role of prognostic nutritional index(PNI) in gastric cancer patients with peritoneal dissemination remains unclear. This study aims to explore the role of the PNI in predict... Objective: The predictive and prognostic role of prognostic nutritional index(PNI) in gastric cancer patients with peritoneal dissemination remains unclear. This study aims to explore the role of the PNI in predicting outcomes of gastric cancer patients with peritoneal dissemination.Methods: A total of 660 patients diagnosed with gastric adenocarcinoma with peritoneal metastasis between January 2000 and April 2014 at Sun Yat-sen University Cancer Center and the Sixth Affiliated Hospital of Sun Yatsen University were retrospectively analyzed. The clinicopathologic characteristics and clinical outcomes of patients with peritoneal dissemination were analyzed.Results: Compared with PNI-high group, PNI-low group was correlated with advanced age(P=0.036), worse performance status(P0.001), higher frequency of ascites(P0.001) and higher frequency of multisite distant metastasis(P0.001). Kaplan-Meier survival curves showed that PNI-high group had a significantly longer median overall survival than PNI-low group(13.13 vs. 9.03 months, P0.001). Multivariate survival analysis revealed that Borrmann type IV(P=0.014), presence of ascites(P=0.017) and lower PNI(P=0.041) were independent poor prognostic factors, and palliative surgery(P0.001) and first-line chemotherapy(P0.001) were good prognostic factors. For patients receiving palliative surgery, the postoperative morbidity rates in the PNI-low group and PNIhigh group were 9.1% and 9.9%, respectively(P=0.797). The postoperative mortality rate was not significantly different between PNI-low and PNI-high groups(2.3% vs. 0.9%, P=0.362).Conclusions: PNI is a useful and practical tool for evaluating the nutritional status of gastric cancer patients with peritoneal dissemination, and is an independent prognostic factor for these patients. 展开更多
关键词 Prognostic nutritional index(PNI) gastric cancer peritoneal dissemination SURVIVAL
下载PDF
Use of high-resolution X-ray computed tomography and 3D image analysis to quantify mineral dissemination and pore space in oxide copper ore particles 被引量:8
20
作者 Bao-hua Yang Ai-xiang Wu +2 位作者 Guillermo A.Narsilio Xiu-xiu Miao Shu-yue Wu 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2017年第9期965-973,共9页
Mineral dissemination and pore space distribution in ore particles are important features that influence heap leaching performance. To quantify the mineral dissemination and pore space distribution of an ore particle,... Mineral dissemination and pore space distribution in ore particles are important features that influence heap leaching performance. To quantify the mineral dissemination and pore space distribution of an ore particle, a cylindrical copper oxide ore sample (I center dot 4.6 mm x 5.6 mm) was scanned using high-resolution X-ray computed tomography (HRXCT), a nondestructive imaging technology, at a spatial resolution of 4.85 mu m. Combined with three-dimensional (3D) image analysis techniques, the main mineral phases and pore space were segmented and the volume fraction of each phase was calculated. In addition, the mass fraction of each mineral phase was estimated and the result was validated with that obtained using traditional techniques. Furthermore, the pore phase features, including the pore size distribution, pore surface area, pore fractal dimension, pore centerline, and the pore connectivity, were investigated quantitatively. The pore space analysis results indicate that the pore size distribution closely fits a log-normal distribution and that the pore space morphology is complicated, with a large surface area and low connectivity. This study demonstrates that the combination of HRXCT and 3D image analysis is an effective tool for acquiring 3D mineralogical and pore structural data. 展开更多
关键词 high-resolution X-ray computed tomography 3D image analysis ore particles mineral dissemination pore space
下载PDF
上一页 1 2 19 下一页 到第
使用帮助 返回顶部