Purpose: The study investigated the impact of dietary habits, specifically soda, milk kefir, water kefir, almond milk, and distilled water (control) consumption, on the microhardness of gingiva-coloured composite and ...Purpose: The study investigated the impact of dietary habits, specifically soda, milk kefir, water kefir, almond milk, and distilled water (control) consumption, on the microhardness of gingiva-coloured composite and acrylic denture bases. Methods: Materials included gingiva-coloured composite (Fusion Universal G1), acrylic (Imicryl), and subdivided Procryla group. Subgroups comprised 15 and 30-minute heat polymerized (Pro15, Pro30), and 1 wt% (Pro1Z) and 3 wt% (Pro3Z) zirconium added groups. Immersed in beverages for 1, 7, and 14 days, pH and microhardness were assessed. SEM examined random samples. Statistical analysis used repeated measures ANOVA, and post hoc tests (p Results: The gingiva-coloured composites displayed noteworthy time-associated microhardness changes (p 0.05). Despite variable pH levels in beverages, no substantial group interaction effects were observed (p > 0.05). Initial microhardness rankings shifted after a 14-day immersion. Conclusions: Gingiva-coloured composite exhibited the highest microhardness pre- and post-immersion, followed by Procryla30 and Imicryl groups. .展开更多
The most commonly used material for constructing complete dentures is polymethyl methacrylate (PMMA). However, the strength characteristics of PMMA, such as impact strength and fatigue strength, are poor, and fracturi...The most commonly used material for constructing complete dentures is polymethyl methacrylate (PMMA). However, the strength characteristics of PMMA, such as impact strength and fatigue strength, are poor, and fracturing of PMMA dentures is a common problem in prosthodontic practice. Reinforcing PMMA with various materials, such as carbon fibers, glass fibers (fiberglass), and ultrahigh modulus polyethylene fibers, has been suggested to strengthen the denture-base material. A common problem encountered when packing the resin on these specimens is fiber slippage beyond the denture edges. The present study proposes an alternative method of incorporating fiber meshes into complete dentures, whereby a thin filament of self-polymerizing resin at the perimeter of the fiber mesh is produced, giving a clear and stable shape to the mesh that fits the upper jaw cast. During placement of the shaped mesh on the cast, a positive-negative relationship is created between the mesh and cast, which immobilizes the mesh during the incorporation process.展开更多
Objective:To investigate the effect of Phyllanthus emblica(P.emblica) Linn,ethanolic extract on the adhesion of Candida albicans(C.albicans) to human buccal epithelial cells(BECs) and denture acrylic surfaces.Methods:...Objective:To investigate the effect of Phyllanthus emblica(P.emblica) Linn,ethanolic extract on the adhesion of Candida albicans(C.albicans) to human buccal epithelial cells(BECs) and denture acrylic surfaces.Methods:Human BECs and transparent acrylic strips were pretreated with ethanolic extract solution of P.emblica fruits at concentration ranged from 18.7 to 300 mg/mL.After washing BECs and the strips were inoculated with three strains of C.albicans (ATCC 10281 and two clinical isolates)(10~7 cells/mL).Normal saline solution(NSS) and 0.2% chlorhexidine gluconate were used as negative and positive controls,respectively.BECs were harvested on 12μm-polycarbonate filters(Millipore,USA).The membrane filters and the strips were stained with Gram stain.Adherent yeast cells on 100 randomly selected epithelial cells and 20 randomly selected fields on each strip were counted under microscope.The statistical significance was calculated by Kruskal-Wallis and Tukey tests at a significant level of P【0.05. Results:Significant lower numbers of all strains of yeasts adhering to BECs and acrylic strips were observed after exposure to 75-300 mg/mL of plant extract compared with NSS.Conclusions: The present study demonstrates that P.emblica ethanolic extract interferes with the adhesion of C. albicans to BECs and denture acrylic surfaces in vitro.展开更多
The aim of the study was to evaluate the effect of adding acrylamide monomer (AAm) on the characterization, flexural strength, flexural modulus and thermal degradation temperature of poly(methyl methacrylate) (P...The aim of the study was to evaluate the effect of adding acrylamide monomer (AAm) on the characterization, flexural strength, flexural modulus and thermal degradation temperature of poly(methyl methacrylate) (PMMA) denture-base resins. Specimens (n= 10) were fabricated from a conventional heat-activated QC-20 (Qc-) and a microwave heat-activated Acron MC (Ac-) PMMA resins. Powder/ liquid ratio followed the manufacturer's instructions for the control groups (Qc-c and Ac-c) and for the copolymer groups, the resins were prepared with 5% (-5), 10% (- 10), 15% (- 15) and 20% (-20) acrylamide contents, according to the molecular weight ratio, respectively. The flexural strength and flexural modulus were measured by a three-point bending test. The data obtained were statistically analyzed by Kruskal-Wallis test (a=O.05) to determine significant differences between the groups, The chemical structures of the resins were characterized by the nuclear magnetic resonance spectroscopy. Thermal stabilities were determined by thermogravimetric analysis (TGA) with a heating rate of 10 ~C.min-1 from 35 ~C to 600 ~C. Control groups from both acrylic resins showed the lowest flexural strength values. Qc-15 showed significant increase in the flexural strength when compared to Qc-c (P〈O.01). Ac-10 and Ac-15 showed significance when compared to Ac-c (P〈O.01). Acrylamide incorporation increased the elastic modulus in Qc-10, Qc-15 and Qc-20 when compared to Qc-c (P〈0.01). Also significant increase was observed in Ac-10, Ac-15 and Ac-20 copolymer groups when compared to Ac-c (P〈0.01). According to the 1H-nuclear magnetic resonance (NMR) results, acrylamide copolymerization was confirmed in the experimental groups. TGA results showed that the thermal stability of PMMA is increased by the insertion of AAm.展开更多
Severe dementia, including Alzheimer’s disease, is intractable and progressive. The purpose of this study was to document the improvement observed in two cases of severe dementia after denture placement. The subjects...Severe dementia, including Alzheimer’s disease, is intractable and progressive. The purpose of this study was to document the improvement observed in two cases of severe dementia after denture placement. The subjects, two women in their 70s with severe dementia, were diagnosed with Alzheimer’s disease by the medical doctors in charge of their cases. In the first case, the subject’s symptoms included severe disorientation, impaired communication, and a tendency to wander. Two weeks after a lower complete denture placement, she was able to greet others. Five weeks later, she was able to communicate and precisely read an analog clock. Her condition continued to improve for at least 3 months. In the second case, the subject’s mouth was always open. She was bedridden in a vegetative state and hardly moved, talked, or laughed;it was impossible to communicate with her. Only a few seconds after an upper complete denture placement, she started to talk, albeit unintelligibly. Two weeks after a lower complete denture placement, she could communicate normally, laugh, and walk without help. Although the underlying mechanism has not yet been clarified, the author hypothesizes that positive signals from the oral area are transferred to the brain as positive stimulation via the trigeminal nerve, the largest cranial nerve.展开更多
Objective:To investigate effect of Boesenbergia pandurata(B.pandurata) rhizome extract on adhesion of Candida albicans(C.albicans) to acrylic surface.Methods:Transparent acrylic strips were prepared and divided into t...Objective:To investigate effect of Boesenbergia pandurata(B.pandurata) rhizome extract on adhesion of Candida albicans(C.albicans) to acrylic surface.Methods:Transparent acrylic strips were prepared and divided into three groups with pretreatment by extract solution of B. pandurata rhizome at concentration of 25,50 and 100 mg/mL,respectively.After washing, the strips were then inoculated with two strains of C.albicans(ATCC13803 and the clinical isolate)(10~7 cells/mL).Normal saline solution and 0.2%chlorhexidine gluconate were used as negative and positive controls,respectively.Stained the strips with modified Cram stain without counterstain.Adherent yeast cells were direct counted under microscope(OlympusCX31, Japan) in 20 randomly selected fields on each strip.The statistical significance was calculated by Kruskal-Wallis and Mann-Whitney non-parametric tests at a significance level of P 【 0.05.Results:Pretreatment with B.pandurata extract significantly reduced the adhesion of both strains of C.albicans to acrylic surfaces in a dose dependent manner.Conclusions: This observation indicates that B.pandurata extract has an inhibitory effect on the ability of C. albicans to adhere to denture acrylic and could be employed as an antifungal agent for preventing denture stomatitis.展开更多
Objective:To study the relationship between plasma treatment time acrylic resin denture material in the size of 2 mm × 10 mm × 10 mm. and efficacy. Methods:Test specimens were prepared from an Plasma treat...Objective:To study the relationship between plasma treatment time acrylic resin denture material in the size of 2 mm × 10 mm × 10 mm. and efficacy. Methods:Test specimens were prepared from an Plasma treatment was carried out on the surface of Polymethyl methacrylate(PMMA) at different time. XPS studies, IR spectra studies and measurement of wetting angle were performed. Results: XPS showed the peak corresponding to C-O getting higher as the treatment proceeded, however at 120 seconds, the peak did not increase any longer and partly crossed with the peak at the duration of 60 seconds. IR spectra showed the wave corresponding to C-H was reduced as O2-plasma treatment proceeded, and then changed little, Wetting angle initially decreased dramatically, however, as the reaction proceeded, wetting angle increased slightly. Conclusion:Equilibrium was reached for introducing oxygen-containing groups and changing of C-H. As the treatment proceeded, wetting angle increased slightly.展开更多
The aim of this research is to clarify whether the midline axis of the complete upper denture (CUD) is the axis of its torsion during loading, apart from the known bending deflection. Furthermore the present study is ...The aim of this research is to clarify whether the midline axis of the complete upper denture (CUD) is the axis of its torsion during loading, apart from the known bending deflection. Furthermore the present study is intended to estimate the influence of the anterior notches on the torsional deformation of the CUD. Using commercial edentulous molds and standardized procedures, six identical CUDs were fabricated with an initial fraenal notch of 5 mm. Two additional notch conditions were produced by deepening the notch to a total depth of 9 mm and by creating an incisal diastema of 7 mm. Five biaxial (also known as “fish bone”) strain gauges were cemented onto the palatal section of the dentures so that their middle axis coincided with the midline axis of the outer surface of the denture. For the denture specimen used in this study, the specific point of torsion was detected 2 cm from the point of contact of the two artificial central incisors. The presence of a deep fraenal notch and the combination of the deep fraenal notch with the presence of an incisal diastema increased the torsion of the CUD to a significant level (P = 0.006 and P = 0.05, respectively). It was shown that the midline can be the CUD’s axis of torsion. Biaxial strain gauges could be a reliable method of measuring the torsional deformation of the CUD.展开更多
This article reviews the literatures dealing with the lingualized occlusion of complete denture including the origin,development and research.Lingualized occlusion is a valuable concept because many advantages of anat...This article reviews the literatures dealing with the lingualized occlusion of complete denture including the origin,development and research.Lingualized occlusion is a valuable concept because many advantages of anatomic and nonanatomic occlusions are retained,satisfactory occlusion is easily obtained,balanced occlusion can be accomplished.展开更多
This study was conducted to investigate the maxillary denture bases and occlusal discrepancies using the Vertex Thermosens in comparison with the conventional polymethyl-methacrylate materials. Twenty maxillary dentur...This study was conducted to investigate the maxillary denture bases and occlusal discrepancies using the Vertex Thermosens in comparison with the conventional polymethyl-methacrylate materials. Twenty maxillary denture bases were prepared from the Vertex ThermoSens and a conventional heat-cured denture base materials. Acrylic maxillary second molars were arranged in their respective positions on the ridge. After curing of both types of denture bases, they were deflasked with their respective master casts. Reference points were prepared for measurements of the antero-posterior and cross-arch dimensions at the denture borders using caliper device. Furthermore, the teeth discrepancies were measured between reference points in the ligual aspect of the second maxillary molars. The recorded data was analyzed using SPSS statistical software version 20. The results showed initial shrinkage of both denture bases in the antero-posterior and cross-arch dimensions immediately after decasting. This contraction was compensated gradually during storage in water up to 2 weeks. Regarding the variable time, there was a significant difference between the tested materials. Moreover, the results revealed occlusal discrepancies and shifting of teeth inward immediately after decasting, followed by outward movement after storage in water for 2 weeks. Regarding the variables time and materials, there were significant differences. Both materials exhibited inward shrinkage in the antero-posterior and cross-arch dimensions immediately after decasting. Both denture bases showed inward shifting of teeth immediately after decasting, followed by outward movement after storage in water up to 2 weeks.展开更多
Aim: Both conventional and flexible resins may show color alteration due to intrinsic and extrinsic factors. The aim of this study was to evaluate the color changes of the polyamid and heat polymerized acrylic denture...Aim: Both conventional and flexible resins may show color alteration due to intrinsic and extrinsic factors. The aim of this study was to evaluate the color changes of the polyamid and heat polymerized acrylic denture base materials in storage of different staining solutions. Methods: Two denture base materials were used in this study. The speciemens were stored in two staining solutions (tea, coffee), distilled water and denture cleaner. For each group, 14 speciemens (25 × 15 × 2.5 mm) were prepared. The color of speciemens was measured using a colorimeter according to the CIE L*a*b* color scale. The color changes of speciemens were evaluated before and after 7 and 30 days. All data recorded were taken by the same investigator to minimize inconstancy of technique. The data were analyzed statistically by repeated measures analysis of variance and Tukey honestly significant difference multiple comparison tests. It was found no statistically significant difference between solutions (P > 0.05). Results: Polyamid denture base resin displayed the greatest colour change when compared to polymetyhl methacrylate denture base resin (P < 0.001). Polyamid material indicated the highest value (ΔE: 7.28) in coffee solution for 7 days. Significance: The colour stability of polymetyhl methacrylate denture base resin is greater than polyamid denture base resin.展开更多
A novel kind of denture base nanocomposite was prepared by polymethyl methyacrylate(PMMA) and cethyltrimethylammonium bromide modified organic montmorillonite (OMMT). The dispersion of montmorillonite in the polym...A novel kind of denture base nanocomposite was prepared by polymethyl methyacrylate(PMMA) and cethyltrimethylammonium bromide modified organic montmorillonite (OMMT). The dispersion of montmorillonite in the polymer matrix was characterized by x-ray diffraction (XRD) and transimission electron microscope (TEM).The content of residual MMA in nanocomposites and the amount of MMA released to water from nanocomposites were determined by gas chromatography (GC). The analysis of TEM and XRD showed that exfoliated-intercalated and intercalated nanocomposites were formed when the content of OMMT was 3% and 5% in the PMMA powder respectively. The results of GC showed that the residual MMA increased with the increase of OMMT content in the polymer matrix. After 7 days in water, the amount of MMA released into water from the nanocomposites tended to be stable. The results of one-way ANOVA and t-test showed that OMMT gave a significant increase of residual MMA concentration (p〈0.05) in nanocomposites.展开更多
The effects of 3 chairside polishing kits and mechanical brushing on the surface roughness of 3 different acrylic denture base resins were compared. Acrylic denture base resins (auto-polymerizing, heat-polymerizing, ...The effects of 3 chairside polishing kits and mechanical brushing on the surface roughness of 3 different acrylic denture base resins were compared. Acrylic denture base resins (auto-polymerizing, heat-polymerizing, injected heat-polymerizing resins) were examined after a tungsten carbide bur, and after chairside polishing using 3 polishing kits and pumice. The specimens were subjected to mechanical brushing using a wear tester to simulate 30 000 strokes of brushing. The surface roughness of the acrylic denture base resin specimens was measured using a contact pro-filometer. After the test, the random polished acrylic resins were evaluated by scanning electron mi-croscopy (SEM) and atomic force microscopy (AFM). Acrylic denture base resins polished using the 3 types of polishing kits had a smoother surface than those finished with the tungsten carbide bur (p〈0.05). The surface of the resin polished by a TC cutter exceeded the Ra of 0.2 μm (p〈0.05). The auto-polymerizing resin showed a significantly higher surface roughness than the heat-polymerizing resin and injected heat-polymerizing resin (p〉0.05). In the case of polishing step wise, there was almost no change in surface roughness after brushing (p〉0.05).展开更多
To develop a new kind of denture adhesive (DA), then to evaluate its mechanical and chemical properties, polyethylene oxide, methyl cellulose, sodium alginate, and cellulose ether, were viewed as four main factors, ...To develop a new kind of denture adhesive (DA), then to evaluate its mechanical and chemical properties, polyethylene oxide, methyl cellulose, sodium alginate, and cellulose ether, were viewed as four main factors, which would affect bonding load of DA, while two levels of each component were differentiated. Following table L12(211), twelve different formulae were designed by orthogonal design and bonding load values were recorded. According to bonding load of each formula, the optimized formula was selected out as this new adhesive material, Comfort-DA II. The changing of bonding load values of Comfort-DA II marinating in artificial saliva were measured, and an existing product, Protefix and Comfort-DA, were used as controls. Following initial load readings, samples and controls were measured from 1- to 12- hour intervals, respectively. Comfort-DA II was diluted at 1.0%, 2.0%, 3.3%, 5.0%, and 10.0% concentrations, and pH values were measured at 1-, 2-, 3-, 4-, 5-, 6-, and 8-hour intervals. Comfort-DA II presented as a pale-yellow paste. Group 6 gained the highest bonding load value of [193.8 (4.2)] N. The mean bonding load of Comfort-DA II was statistically different to Comfort-DA (p = 0.004) and Protefix (p = 0.006). Comfort-DA II exhibited a progressive increase in pH value over time and was slightly alkaline. Comfort-DA II showed significantly elevated mechanical and chemical properties, comparing to Comfort-DA. The results also indicate that orthogonal design may be an efficacious way to develop new dental materials.展开更多
Introduction: Several techniques have been described by which a pair of dentures may be replicated. Case Report: The method described in this paper used materials readily available in a private practice to generate a ...Introduction: Several techniques have been described by which a pair of dentures may be replicated. Case Report: The method described in this paper used materials readily available in a private practice to generate a pair of duplicate dentures for a 74-year-old Black male, which captured all of the features of the patients’ existing pair. These were modified chair-side and used to capture vital information on fit, occlusion and aesthetics, forming a template which was transferred to the laboratory and used to generate new dentures via the traditional laboratory process. The same template was also used to generate a pair of “AvaDent Digital Dentures” by digital scanning and production of a digital denture template for try and then fabrication of the digital denture. Conclusion: The results of this pilot study show that this simple chair-side method of fabricating duplicate dentures can be incorporated successfully into the AvaDent Digital Denture fabrication process to generate a pair of dentures with comparability if not superior fit and aesthetics to a pair fabricated from the same template via the traditional laboratory process.展开更多
Removable partial dentures (RPDs) (conventional and implant-supported) treatment is considered a viable option to replace missing teeth as inexpensively as possible, but it has limitations. Objectives: This study repo...Removable partial dentures (RPDs) (conventional and implant-supported) treatment is considered a viable option to replace missing teeth as inexpensively as possible, but it has limitations. Objectives: This study reports the effect of gender and location (maxilla vs. mandible) on the clinical performance of removable partial dentures (RPDs). Materials and Methods: A total of 100 Patients who had RPDs delivered between 1990-1995 were evaluated. A 4-point scoring system was used to assess seventeen criteria. These criteria include acceptance, stability, support, retention, adaptation, occlusion, integrity, and design of the pros-theses, rest and rest seat preparation, occlusal wear, esthetics, phonetics, tissue condition, mobility of abutments, gingival and plaque indices. The data were analyzed using Kruskal-Wallis and Mann-Whitney U non-parametric statistical tests. Results: The results showed that acceptance of RPDs was rated the lowest. Other reasons for failure were poor retention, lack of integrity of the prostheses and inadequate adaptation. Retention and design of major connectors attributed to Mandibular RPD failure. Success rate of 75% was observed in male compared with 67.2% for female. Maxillary RPDs showed a higher success rate (78%) compared with the mandibular (70.1%). No significant statistical difference in Alpha scores between female and male patients and between maxillary and mandibular RPDs (p < 0.05). Conclusions: The clinical performance of RPDs showed a higher success rate in male patients compared to female patients and the maxillary RPDs showed a higher success rate compared to mandibular.展开更多
Objective: Infection control protocols dictate the disinfection of dentures. There are no products available which are designed for the specific use of disinfecting dentures. The objective of this study was to investi...Objective: Infection control protocols dictate the disinfection of dentures. There are no products available which are designed for the specific use of disinfecting dentures. The objective of this study was to investigate the impact of chemical disinfectants on elastic modulus, flexural strength and color stability of denture base resins. Methods: 256 specimens from four acrylic denture base resins were manufactured. Two cold-curing denture base resins: PalaXpress (Heraeus Kulzer, Hanau, Germany), Futura Gen (Schuetz Dental, Roßbach, Germany) and two heat-curing denture base resins: Paladon 65 (Heraeus Kulzer, Hanau, Germany), FuturAcryl 2000 (Schuetz Dental, Roßbach, Germany) were used. Three chemical disinfecting agents were tested: Impresept, D050 Instru-Gen, Stammopur DR. Specimens were stored in distilled water and in chemical disinfecting agents. They were divided randomly into groups. E-Modulus and flexural strength were measured using the three-point bending test. Color changes (ΔE) were determined spectrophotometrically. Results: The disinfection agents showed no significant influence on the E-modulus compared to distilled water (Acrylic vs. distilled water from (Futura Gen) 2688.80 ± 230.78 vs. 2766.60 ± 91.22 MPa to (PalaXpress) 3004.20 ± 26.40 vs. 2851.00 ± 95.23 MPa). Flexural strength after storage in distilled water and disinfection did not differ significantly (Acrylic vs. distilled water from (Paladon65) 27.28 ± 1.30 vs. 28.42 ± 0.84 N/mm2, (p > 0.05) to (PalaXpress) 30.88 ± 0.25 vs. 29.68 ± 0.79 N/mm2, p < 0.001). Disinfection caused a significant color change with Impresept of Paladon 65 (p ≤ 0.001), FuturaAcryl 2000 with Stammopur DR and D 050 Instru-Gen (p ≤ 0.001). Conclusions: The investigated disinfection agents did not influence elastic modulus and flexural strength of denture base resins negatively. ΔE-values were in a range of 1 to 2. Thus, the detected color changes may be marginal. Clinical relevance: Single use disinfections are feasible for acrylic dentures regarding to elastic modulus and flexural strength.展开更多
Aim: To compare the chewing process and swallowing threshold parameters of subjects with complete dentures and overdentures with data obtained from subjects with complete natural dentitions. Metho-dology: The chewing ...Aim: To compare the chewing process and swallowing threshold parameters of subjects with complete dentures and overdentures with data obtained from subjects with complete natural dentitions. Metho-dology: The chewing process in terms of swallowing threshold parameters of four groups of subjects with complete dentures (all females) was quantified by sieving particles after chewing of an artificial test ‘food’ and compared with that of subjects with com-plete natural dentitions as a reference group (33 sub-jects). All subjects (except those of the reference group) had a complete denture in the upper jaw. Regarding the lower jaw two groups with complete dentures (with high (24 subjects), respectively low mandible (12 subjects)) and two groups with overdentures (implant-retained (22 subjects), respectively natural root supported (19 subjects)) were composed. Results: The ‘overdenture-implants’ group needed significantly more chewing cycles and time (mean: 45 cycles in 32 seconds) until ‘swallowing’ compared to the group with complete natural dentitions (mean: 26 cycles in 19 seconds until ‘swallowing’). Also the ‘complete denture-low mandible’ group needed sig-nificantly more cycles and time (mean: 52 cycles in 44 seconds) until ‘swallowing’ than the complete dentition group. In the ‘overdenture-natural roots’ group these outcomes (33 cycles in 24 seconds) were not significantly different compared with the complete dentition group. The ‘complete denture-high mandi-ble’ group (32 cycles in 26 seconds) needed not sig-nificantly more cycles until ‘swallowing’, however time until ‘swallowing’ was significantly longer com-pared to the complete dentition group. All denture groups had significantly larger mean particle sizes when ‘swallowing’ (sizes in the order of 3 mm) than the natural dentition group (about 2 mm). Conclusion: Despite efforts to compensate for a reduced chewing efficiency, subjects with complete dentures (including overdentures) had 50% larger median particle sizes when ‘swallowing’ compared to subjects with complete natural dentitions.展开更多
The aim of this study was to evaluate the Vickers Hardness of four different denture base materials. Four different denture base materials were used in this study: Heat-cured pink acrylic resin, self-cured acrylic res...The aim of this study was to evaluate the Vickers Hardness of four different denture base materials. Four different denture base materials were used in this study: Heat-cured pink acrylic resin, self-cured acrylic resin, heat-cured clear acrylic resin and polyamide denture base materials. To-tally 80 disc shaped samples which 2 mm thickness and 40 mm diameter were prepared. The samples were stored in distilled water after polished. Then, Vickers Hardness test was performed with TMTeck HV-1000B (200 gram at 15 second). The statistically analysis of obtained data was performed with use one-way analysis of variance test. The results showed that the highest Vickers Hardness value (18.57 HV) was identified in heat-cured (pink) acrylic resin, the lowest Vickers Hardness value (9.62 HV) was identified in polyamide denture base materials. The result of one-way analysis of variance test showed that there were statistically very highly significant differences between four denture base materials of Vickers Hardness (p < 0.001). The obtained data presented that the self-cured denture base acrylic resin was the hardnest denture base materials.展开更多
We aimed to evaluate the microbial and inflammatory characteristics associated with Denture Stomatitis (DS) analyzing: l) Levels of salivary cytokines and cultivable C. albicans;2) DNA-DNA checkerboard on biofilm asso...We aimed to evaluate the microbial and inflammatory characteristics associated with Denture Stomatitis (DS) analyzing: l) Levels of salivary cytokines and cultivable C. albicans;2) DNA-DNA checkerboard on biofilm associated with mucosal tissue-bearing denture surfaces, 3) Serum C-reactive protein (CRP) levels. Thirty-two subjects were enrolled in the study with control (n = 17) and DS types II and III (n = 15) subjects. Samples were collected from unstimulated whole saliva, serum and swabs from denture surfaces. Salivary levels of inflammatory mediators and CRP were measured by multiplex. Samples from denture and mucosal surfaces were analyzed by DNA-DNA checkerboard. Saliva from DS subjects showed increase in IL-8 (p = 0.04) and IL-1β (p = 0.04) with trend for increase in IL-1β, TNFα and IL-6 levels. C. albicans higher counts in DS saliva (p = 0.03) showed association with elevated levels of IL-8 (p = 0.03) and IL-1α (p = 0.01). CRP levels were not different among groups (p = 0.74). DNA-DNA checkerboard analyses indicated typical periodontal pathogens below the detection threshold of 104 organisms on both denture and inflamed mucosal surfaces. The data suggest that DS is associated with elevation of salivary IL1 and IL-8 together with increased C. albicans. There was no evidence of systemic inflammation as measured by serum C-reactive protein levels.展开更多
文摘Purpose: The study investigated the impact of dietary habits, specifically soda, milk kefir, water kefir, almond milk, and distilled water (control) consumption, on the microhardness of gingiva-coloured composite and acrylic denture bases. Methods: Materials included gingiva-coloured composite (Fusion Universal G1), acrylic (Imicryl), and subdivided Procryla group. Subgroups comprised 15 and 30-minute heat polymerized (Pro15, Pro30), and 1 wt% (Pro1Z) and 3 wt% (Pro3Z) zirconium added groups. Immersed in beverages for 1, 7, and 14 days, pH and microhardness were assessed. SEM examined random samples. Statistical analysis used repeated measures ANOVA, and post hoc tests (p Results: The gingiva-coloured composites displayed noteworthy time-associated microhardness changes (p 0.05). Despite variable pH levels in beverages, no substantial group interaction effects were observed (p > 0.05). Initial microhardness rankings shifted after a 14-day immersion. Conclusions: Gingiva-coloured composite exhibited the highest microhardness pre- and post-immersion, followed by Procryla30 and Imicryl groups. .
文摘The most commonly used material for constructing complete dentures is polymethyl methacrylate (PMMA). However, the strength characteristics of PMMA, such as impact strength and fatigue strength, are poor, and fracturing of PMMA dentures is a common problem in prosthodontic practice. Reinforcing PMMA with various materials, such as carbon fibers, glass fibers (fiberglass), and ultrahigh modulus polyethylene fibers, has been suggested to strengthen the denture-base material. A common problem encountered when packing the resin on these specimens is fiber slippage beyond the denture edges. The present study proposes an alternative method of incorporating fiber meshes into complete dentures, whereby a thin filament of self-polymerizing resin at the perimeter of the fiber mesh is produced, giving a clear and stable shape to the mesh that fits the upper jaw cast. During placement of the shaped mesh on the cast, a positive-negative relationship is created between the mesh and cast, which immobilizes the mesh during the incorporation process.
文摘Objective:To investigate the effect of Phyllanthus emblica(P.emblica) Linn,ethanolic extract on the adhesion of Candida albicans(C.albicans) to human buccal epithelial cells(BECs) and denture acrylic surfaces.Methods:Human BECs and transparent acrylic strips were pretreated with ethanolic extract solution of P.emblica fruits at concentration ranged from 18.7 to 300 mg/mL.After washing BECs and the strips were inoculated with three strains of C.albicans (ATCC 10281 and two clinical isolates)(10~7 cells/mL).Normal saline solution(NSS) and 0.2% chlorhexidine gluconate were used as negative and positive controls,respectively.BECs were harvested on 12μm-polycarbonate filters(Millipore,USA).The membrane filters and the strips were stained with Gram stain.Adherent yeast cells on 100 randomly selected epithelial cells and 20 randomly selected fields on each strip were counted under microscope.The statistical significance was calculated by Kruskal-Wallis and Tukey tests at a significant level of P【0.05. Results:Significant lower numbers of all strains of yeasts adhering to BECs and acrylic strips were observed after exposure to 75-300 mg/mL of plant extract compared with NSS.Conclusions: The present study demonstrates that P.emblica ethanolic extract interferes with the adhesion of C. albicans to BECs and denture acrylic surfaces in vitro.
文摘The aim of the study was to evaluate the effect of adding acrylamide monomer (AAm) on the characterization, flexural strength, flexural modulus and thermal degradation temperature of poly(methyl methacrylate) (PMMA) denture-base resins. Specimens (n= 10) were fabricated from a conventional heat-activated QC-20 (Qc-) and a microwave heat-activated Acron MC (Ac-) PMMA resins. Powder/ liquid ratio followed the manufacturer's instructions for the control groups (Qc-c and Ac-c) and for the copolymer groups, the resins were prepared with 5% (-5), 10% (- 10), 15% (- 15) and 20% (-20) acrylamide contents, according to the molecular weight ratio, respectively. The flexural strength and flexural modulus were measured by a three-point bending test. The data obtained were statistically analyzed by Kruskal-Wallis test (a=O.05) to determine significant differences between the groups, The chemical structures of the resins were characterized by the nuclear magnetic resonance spectroscopy. Thermal stabilities were determined by thermogravimetric analysis (TGA) with a heating rate of 10 ~C.min-1 from 35 ~C to 600 ~C. Control groups from both acrylic resins showed the lowest flexural strength values. Qc-15 showed significant increase in the flexural strength when compared to Qc-c (P〈O.01). Ac-10 and Ac-15 showed significance when compared to Ac-c (P〈O.01). Acrylamide incorporation increased the elastic modulus in Qc-10, Qc-15 and Qc-20 when compared to Qc-c (P〈0.01). Also significant increase was observed in Ac-10, Ac-15 and Ac-20 copolymer groups when compared to Ac-c (P〈0.01). According to the 1H-nuclear magnetic resonance (NMR) results, acrylamide copolymerization was confirmed in the experimental groups. TGA results showed that the thermal stability of PMMA is increased by the insertion of AAm.
文摘Severe dementia, including Alzheimer’s disease, is intractable and progressive. The purpose of this study was to document the improvement observed in two cases of severe dementia after denture placement. The subjects, two women in their 70s with severe dementia, were diagnosed with Alzheimer’s disease by the medical doctors in charge of their cases. In the first case, the subject’s symptoms included severe disorientation, impaired communication, and a tendency to wander. Two weeks after a lower complete denture placement, she was able to greet others. Five weeks later, she was able to communicate and precisely read an analog clock. Her condition continued to improve for at least 3 months. In the second case, the subject’s mouth was always open. She was bedridden in a vegetative state and hardly moved, talked, or laughed;it was impossible to communicate with her. Only a few seconds after an upper complete denture placement, she started to talk, albeit unintelligibly. Two weeks after a lower complete denture placement, she could communicate normally, laugh, and walk without help. Although the underlying mechanism has not yet been clarified, the author hypothesizes that positive signals from the oral area are transferred to the brain as positive stimulation via the trigeminal nerve, the largest cranial nerve.
文摘Objective:To investigate effect of Boesenbergia pandurata(B.pandurata) rhizome extract on adhesion of Candida albicans(C.albicans) to acrylic surface.Methods:Transparent acrylic strips were prepared and divided into three groups with pretreatment by extract solution of B. pandurata rhizome at concentration of 25,50 and 100 mg/mL,respectively.After washing, the strips were then inoculated with two strains of C.albicans(ATCC13803 and the clinical isolate)(10~7 cells/mL).Normal saline solution and 0.2%chlorhexidine gluconate were used as negative and positive controls,respectively.Stained the strips with modified Cram stain without counterstain.Adherent yeast cells were direct counted under microscope(OlympusCX31, Japan) in 20 randomly selected fields on each strip.The statistical significance was calculated by Kruskal-Wallis and Mann-Whitney non-parametric tests at a significance level of P 【 0.05.Results:Pretreatment with B.pandurata extract significantly reduced the adhesion of both strains of C.albicans to acrylic surfaces in a dose dependent manner.Conclusions: This observation indicates that B.pandurata extract has an inhibitory effect on the ability of C. albicans to adhere to denture acrylic and could be employed as an antifungal agent for preventing denture stomatitis.
基金This work was supported by Science Fund of Department of Education of Jiangsu Province(06KJD320125)
文摘Objective:To study the relationship between plasma treatment time acrylic resin denture material in the size of 2 mm × 10 mm × 10 mm. and efficacy. Methods:Test specimens were prepared from an Plasma treatment was carried out on the surface of Polymethyl methacrylate(PMMA) at different time. XPS studies, IR spectra studies and measurement of wetting angle were performed. Results: XPS showed the peak corresponding to C-O getting higher as the treatment proceeded, however at 120 seconds, the peak did not increase any longer and partly crossed with the peak at the duration of 60 seconds. IR spectra showed the wave corresponding to C-H was reduced as O2-plasma treatment proceeded, and then changed little, Wetting angle initially decreased dramatically, however, as the reaction proceeded, wetting angle increased slightly. Conclusion:Equilibrium was reached for introducing oxygen-containing groups and changing of C-H. As the treatment proceeded, wetting angle increased slightly.
文摘The aim of this research is to clarify whether the midline axis of the complete upper denture (CUD) is the axis of its torsion during loading, apart from the known bending deflection. Furthermore the present study is intended to estimate the influence of the anterior notches on the torsional deformation of the CUD. Using commercial edentulous molds and standardized procedures, six identical CUDs were fabricated with an initial fraenal notch of 5 mm. Two additional notch conditions were produced by deepening the notch to a total depth of 9 mm and by creating an incisal diastema of 7 mm. Five biaxial (also known as “fish bone”) strain gauges were cemented onto the palatal section of the dentures so that their middle axis coincided with the midline axis of the outer surface of the denture. For the denture specimen used in this study, the specific point of torsion was detected 2 cm from the point of contact of the two artificial central incisors. The presence of a deep fraenal notch and the combination of the deep fraenal notch with the presence of an incisal diastema increased the torsion of the CUD to a significant level (P = 0.006 and P = 0.05, respectively). It was shown that the midline can be the CUD’s axis of torsion. Biaxial strain gauges could be a reliable method of measuring the torsional deformation of the CUD.
文摘This article reviews the literatures dealing with the lingualized occlusion of complete denture including the origin,development and research.Lingualized occlusion is a valuable concept because many advantages of anatomic and nonanatomic occlusions are retained,satisfactory occlusion is easily obtained,balanced occlusion can be accomplished.
文摘This study was conducted to investigate the maxillary denture bases and occlusal discrepancies using the Vertex Thermosens in comparison with the conventional polymethyl-methacrylate materials. Twenty maxillary denture bases were prepared from the Vertex ThermoSens and a conventional heat-cured denture base materials. Acrylic maxillary second molars were arranged in their respective positions on the ridge. After curing of both types of denture bases, they were deflasked with their respective master casts. Reference points were prepared for measurements of the antero-posterior and cross-arch dimensions at the denture borders using caliper device. Furthermore, the teeth discrepancies were measured between reference points in the ligual aspect of the second maxillary molars. The recorded data was analyzed using SPSS statistical software version 20. The results showed initial shrinkage of both denture bases in the antero-posterior and cross-arch dimensions immediately after decasting. This contraction was compensated gradually during storage in water up to 2 weeks. Regarding the variable time, there was a significant difference between the tested materials. Moreover, the results revealed occlusal discrepancies and shifting of teeth inward immediately after decasting, followed by outward movement after storage in water for 2 weeks. Regarding the variables time and materials, there were significant differences. Both materials exhibited inward shrinkage in the antero-posterior and cross-arch dimensions immediately after decasting. Both denture bases showed inward shifting of teeth immediately after decasting, followed by outward movement after storage in water up to 2 weeks.
基金supported financially by the Department of Scientific Research Projects of Ataturk University(Project No.2003/158)and(Project no.2010/141).
文摘Aim: Both conventional and flexible resins may show color alteration due to intrinsic and extrinsic factors. The aim of this study was to evaluate the color changes of the polyamid and heat polymerized acrylic denture base materials in storage of different staining solutions. Methods: Two denture base materials were used in this study. The speciemens were stored in two staining solutions (tea, coffee), distilled water and denture cleaner. For each group, 14 speciemens (25 × 15 × 2.5 mm) were prepared. The color of speciemens was measured using a colorimeter according to the CIE L*a*b* color scale. The color changes of speciemens were evaluated before and after 7 and 30 days. All data recorded were taken by the same investigator to minimize inconstancy of technique. The data were analyzed statistically by repeated measures analysis of variance and Tukey honestly significant difference multiple comparison tests. It was found no statistically significant difference between solutions (P > 0.05). Results: Polyamid denture base resin displayed the greatest colour change when compared to polymetyhl methacrylate denture base resin (P < 0.001). Polyamid material indicated the highest value (ΔE: 7.28) in coffee solution for 7 days. Significance: The colour stability of polymetyhl methacrylate denture base resin is greater than polyamid denture base resin.
文摘A novel kind of denture base nanocomposite was prepared by polymethyl methyacrylate(PMMA) and cethyltrimethylammonium bromide modified organic montmorillonite (OMMT). The dispersion of montmorillonite in the polymer matrix was characterized by x-ray diffraction (XRD) and transimission electron microscope (TEM).The content of residual MMA in nanocomposites and the amount of MMA released to water from nanocomposites were determined by gas chromatography (GC). The analysis of TEM and XRD showed that exfoliated-intercalated and intercalated nanocomposites were formed when the content of OMMT was 3% and 5% in the PMMA powder respectively. The results of GC showed that the residual MMA increased with the increase of OMMT content in the polymer matrix. After 7 days in water, the amount of MMA released into water from the nanocomposites tended to be stable. The results of one-way ANOVA and t-test showed that OMMT gave a significant increase of residual MMA concentration (p〈0.05) in nanocomposites.
文摘The effects of 3 chairside polishing kits and mechanical brushing on the surface roughness of 3 different acrylic denture base resins were compared. Acrylic denture base resins (auto-polymerizing, heat-polymerizing, injected heat-polymerizing resins) were examined after a tungsten carbide bur, and after chairside polishing using 3 polishing kits and pumice. The specimens were subjected to mechanical brushing using a wear tester to simulate 30 000 strokes of brushing. The surface roughness of the acrylic denture base resin specimens was measured using a contact pro-filometer. After the test, the random polished acrylic resins were evaluated by scanning electron mi-croscopy (SEM) and atomic force microscopy (AFM). Acrylic denture base resins polished using the 3 types of polishing kits had a smoother surface than those finished with the tungsten carbide bur (p〈0.05). The surface of the resin polished by a TC cutter exceeded the Ra of 0.2 μm (p〈0.05). The auto-polymerizing resin showed a significantly higher surface roughness than the heat-polymerizing resin and injected heat-polymerizing resin (p〉0.05). In the case of polishing step wise, there was almost no change in surface roughness after brushing (p〉0.05).
基金Funded by the Science and Technology Planning Project of Guangdong Province, China (2010B060900045)
文摘To develop a new kind of denture adhesive (DA), then to evaluate its mechanical and chemical properties, polyethylene oxide, methyl cellulose, sodium alginate, and cellulose ether, were viewed as four main factors, which would affect bonding load of DA, while two levels of each component were differentiated. Following table L12(211), twelve different formulae were designed by orthogonal design and bonding load values were recorded. According to bonding load of each formula, the optimized formula was selected out as this new adhesive material, Comfort-DA II. The changing of bonding load values of Comfort-DA II marinating in artificial saliva were measured, and an existing product, Protefix and Comfort-DA, were used as controls. Following initial load readings, samples and controls were measured from 1- to 12- hour intervals, respectively. Comfort-DA II was diluted at 1.0%, 2.0%, 3.3%, 5.0%, and 10.0% concentrations, and pH values were measured at 1-, 2-, 3-, 4-, 5-, 6-, and 8-hour intervals. Comfort-DA II presented as a pale-yellow paste. Group 6 gained the highest bonding load value of [193.8 (4.2)] N. The mean bonding load of Comfort-DA II was statistically different to Comfort-DA (p = 0.004) and Protefix (p = 0.006). Comfort-DA II exhibited a progressive increase in pH value over time and was slightly alkaline. Comfort-DA II showed significantly elevated mechanical and chemical properties, comparing to Comfort-DA. The results also indicate that orthogonal design may be an efficacious way to develop new dental materials.
文摘Introduction: Several techniques have been described by which a pair of dentures may be replicated. Case Report: The method described in this paper used materials readily available in a private practice to generate a pair of duplicate dentures for a 74-year-old Black male, which captured all of the features of the patients’ existing pair. These were modified chair-side and used to capture vital information on fit, occlusion and aesthetics, forming a template which was transferred to the laboratory and used to generate new dentures via the traditional laboratory process. The same template was also used to generate a pair of “AvaDent Digital Dentures” by digital scanning and production of a digital denture template for try and then fabrication of the digital denture. Conclusion: The results of this pilot study show that this simple chair-side method of fabricating duplicate dentures can be incorporated successfully into the AvaDent Digital Denture fabrication process to generate a pair of dentures with comparability if not superior fit and aesthetics to a pair fabricated from the same template via the traditional laboratory process.
文摘Removable partial dentures (RPDs) (conventional and implant-supported) treatment is considered a viable option to replace missing teeth as inexpensively as possible, but it has limitations. Objectives: This study reports the effect of gender and location (maxilla vs. mandible) on the clinical performance of removable partial dentures (RPDs). Materials and Methods: A total of 100 Patients who had RPDs delivered between 1990-1995 were evaluated. A 4-point scoring system was used to assess seventeen criteria. These criteria include acceptance, stability, support, retention, adaptation, occlusion, integrity, and design of the pros-theses, rest and rest seat preparation, occlusal wear, esthetics, phonetics, tissue condition, mobility of abutments, gingival and plaque indices. The data were analyzed using Kruskal-Wallis and Mann-Whitney U non-parametric statistical tests. Results: The results showed that acceptance of RPDs was rated the lowest. Other reasons for failure were poor retention, lack of integrity of the prostheses and inadequate adaptation. Retention and design of major connectors attributed to Mandibular RPD failure. Success rate of 75% was observed in male compared with 67.2% for female. Maxillary RPDs showed a higher success rate (78%) compared with the mandibular (70.1%). No significant statistical difference in Alpha scores between female and male patients and between maxillary and mandibular RPDs (p < 0.05). Conclusions: The clinical performance of RPDs showed a higher success rate in male patients compared to female patients and the maxillary RPDs showed a higher success rate compared to mandibular.
文摘Objective: Infection control protocols dictate the disinfection of dentures. There are no products available which are designed for the specific use of disinfecting dentures. The objective of this study was to investigate the impact of chemical disinfectants on elastic modulus, flexural strength and color stability of denture base resins. Methods: 256 specimens from four acrylic denture base resins were manufactured. Two cold-curing denture base resins: PalaXpress (Heraeus Kulzer, Hanau, Germany), Futura Gen (Schuetz Dental, Roßbach, Germany) and two heat-curing denture base resins: Paladon 65 (Heraeus Kulzer, Hanau, Germany), FuturAcryl 2000 (Schuetz Dental, Roßbach, Germany) were used. Three chemical disinfecting agents were tested: Impresept, D050 Instru-Gen, Stammopur DR. Specimens were stored in distilled water and in chemical disinfecting agents. They were divided randomly into groups. E-Modulus and flexural strength were measured using the three-point bending test. Color changes (ΔE) were determined spectrophotometrically. Results: The disinfection agents showed no significant influence on the E-modulus compared to distilled water (Acrylic vs. distilled water from (Futura Gen) 2688.80 ± 230.78 vs. 2766.60 ± 91.22 MPa to (PalaXpress) 3004.20 ± 26.40 vs. 2851.00 ± 95.23 MPa). Flexural strength after storage in distilled water and disinfection did not differ significantly (Acrylic vs. distilled water from (Paladon65) 27.28 ± 1.30 vs. 28.42 ± 0.84 N/mm2, (p > 0.05) to (PalaXpress) 30.88 ± 0.25 vs. 29.68 ± 0.79 N/mm2, p < 0.001). Disinfection caused a significant color change with Impresept of Paladon 65 (p ≤ 0.001), FuturaAcryl 2000 with Stammopur DR and D 050 Instru-Gen (p ≤ 0.001). Conclusions: The investigated disinfection agents did not influence elastic modulus and flexural strength of denture base resins negatively. ΔE-values were in a range of 1 to 2. Thus, the detected color changes may be marginal. Clinical relevance: Single use disinfections are feasible for acrylic dentures regarding to elastic modulus and flexural strength.
文摘Aim: To compare the chewing process and swallowing threshold parameters of subjects with complete dentures and overdentures with data obtained from subjects with complete natural dentitions. Metho-dology: The chewing process in terms of swallowing threshold parameters of four groups of subjects with complete dentures (all females) was quantified by sieving particles after chewing of an artificial test ‘food’ and compared with that of subjects with com-plete natural dentitions as a reference group (33 sub-jects). All subjects (except those of the reference group) had a complete denture in the upper jaw. Regarding the lower jaw two groups with complete dentures (with high (24 subjects), respectively low mandible (12 subjects)) and two groups with overdentures (implant-retained (22 subjects), respectively natural root supported (19 subjects)) were composed. Results: The ‘overdenture-implants’ group needed significantly more chewing cycles and time (mean: 45 cycles in 32 seconds) until ‘swallowing’ compared to the group with complete natural dentitions (mean: 26 cycles in 19 seconds until ‘swallowing’). Also the ‘complete denture-low mandible’ group needed sig-nificantly more cycles and time (mean: 52 cycles in 44 seconds) until ‘swallowing’ than the complete dentition group. In the ‘overdenture-natural roots’ group these outcomes (33 cycles in 24 seconds) were not significantly different compared with the complete dentition group. The ‘complete denture-high mandi-ble’ group (32 cycles in 26 seconds) needed not sig-nificantly more cycles until ‘swallowing’, however time until ‘swallowing’ was significantly longer com-pared to the complete dentition group. All denture groups had significantly larger mean particle sizes when ‘swallowing’ (sizes in the order of 3 mm) than the natural dentition group (about 2 mm). Conclusion: Despite efforts to compensate for a reduced chewing efficiency, subjects with complete dentures (including overdentures) had 50% larger median particle sizes when ‘swallowing’ compared to subjects with complete natural dentitions.
文摘The aim of this study was to evaluate the Vickers Hardness of four different denture base materials. Four different denture base materials were used in this study: Heat-cured pink acrylic resin, self-cured acrylic resin, heat-cured clear acrylic resin and polyamide denture base materials. To-tally 80 disc shaped samples which 2 mm thickness and 40 mm diameter were prepared. The samples were stored in distilled water after polished. Then, Vickers Hardness test was performed with TMTeck HV-1000B (200 gram at 15 second). The statistically analysis of obtained data was performed with use one-way analysis of variance test. The results showed that the highest Vickers Hardness value (18.57 HV) was identified in heat-cured (pink) acrylic resin, the lowest Vickers Hardness value (9.62 HV) was identified in polyamide denture base materials. The result of one-way analysis of variance test showed that there were statistically very highly significant differences between four denture base materials of Vickers Hardness (p < 0.001). The obtained data presented that the self-cured denture base acrylic resin was the hardnest denture base materials.
文摘We aimed to evaluate the microbial and inflammatory characteristics associated with Denture Stomatitis (DS) analyzing: l) Levels of salivary cytokines and cultivable C. albicans;2) DNA-DNA checkerboard on biofilm associated with mucosal tissue-bearing denture surfaces, 3) Serum C-reactive protein (CRP) levels. Thirty-two subjects were enrolled in the study with control (n = 17) and DS types II and III (n = 15) subjects. Samples were collected from unstimulated whole saliva, serum and swabs from denture surfaces. Salivary levels of inflammatory mediators and CRP were measured by multiplex. Samples from denture and mucosal surfaces were analyzed by DNA-DNA checkerboard. Saliva from DS subjects showed increase in IL-8 (p = 0.04) and IL-1β (p = 0.04) with trend for increase in IL-1β, TNFα and IL-6 levels. C. albicans higher counts in DS saliva (p = 0.03) showed association with elevated levels of IL-8 (p = 0.03) and IL-1α (p = 0.01). CRP levels were not different among groups (p = 0.74). DNA-DNA checkerboard analyses indicated typical periodontal pathogens below the detection threshold of 104 organisms on both denture and inflamed mucosal surfaces. The data suggest that DS is associated with elevation of salivary IL1 and IL-8 together with increased C. albicans. There was no evidence of systemic inflammation as measured by serum C-reactive protein levels.