In this work,a six-bed pressure swing adsorption(PSA)process was investigated to produce medical oxygen from air,which uses the combination of six-way rotating distribution valve and PSA and has the main advantage of ...In this work,a six-bed pressure swing adsorption(PSA)process was investigated to produce medical oxygen from air,which uses the combination of six-way rotating distribution valve and PSA and has the main advantage of effectively saving space compared to the traditional two-bed or four-bed PSA process and can obtain greater productivity.The mathematical model of adsorption beds was developed based on the separation mechanism and the interaction among different equipment.Moreover,a pilot-scale device has been constructed to verify the accuracy of mathematical model by experiment.The oxygen product conformed to the medical standard(>93%(vol))with a recovery of over 57%.Some related parameters were also discussed in detail,such as step time,ratio of length to the diameter,flow rate of product.展开更多
Water distribution network(WDN)leakage management has received increased attention in recent years.One of the most successful leakage-control strategies is to divide the network into District Metered Areas(DMAs).As a ...Water distribution network(WDN)leakage management has received increased attention in recent years.One of the most successful leakage-control strategies is to divide the network into District Metered Areas(DMAs).As a multi-staged technique,the generation of DMAs is a difficult task in design and implementation(i.e.,clustering,sectorization,and performance evaluation).Previous studies on DMAs implementation did not consider the potential use of existing valves in achieving the objective.In this work,a methodology is proposed for detecting clusters and reducing the cost of additional valves and DMA sectorization by considering existing valves as much as possible.The procedure of DMAs identification has been divided into three stages,i.e.,a)clusters identification;b)sectorization or boundaries optimization and c)performance evaluation of the partitioned network.The proposed methodology is evaluated on a simple network and a real-world water network with the findings provided and compared to the DMAs,established for a raw water network with no existing valves.It is found that there is an adequate difference in cost of strategy implementation in both the cases for the network under consideration and the existing valve system achieved better network performance in terms of resilience index.展开更多
AIM: To determine the impact of red blood cell distribution width on outcome in anemic patients undergoing transcatheter aortic valve implantation(TAVI).METHODS: In a retrospective single center cohort study we determ...AIM: To determine the impact of red blood cell distribution width on outcome in anemic patients undergoing transcatheter aortic valve implantation(TAVI).METHODS: In a retrospective single center cohort study we determined the impact of baseline red cell distribution width(RDW) and anemia on outcome in 376 patients with aortic stenosis undergoing TAVI. All patients were discussed in the institutional heart team and declined for surgical aortic valve replacement due to high operative risk. Collected data included patient characteristics, imaging findings, periprocedural in hospital data, laboratory results and follow up data. Blood samples for hematology and biochemistry analysis were taken from every patient before and at fixed intervals up to 72 h after TAVI including blood count and creatinine. Descriptive statistics were used for patient's characteristics. KaplanMeier survival curves were used for time to event outcomes. A recursive partitioning regression and classification was used to investigate the association between potential risk factors and outcome variables.RESULTS: Mean age in our study population was 81 ± 6.1 years. Anemia was prevalent in 63.6%(n = 239) of our patients. Age and creatinine were identified as risk factors for anemia. In our study population, anemia per se did influence 30-d mortality but did not predict longterm mortality. In contrast, a RDW > 14% showed to be highly predictable for a reduced short- and longterm survival in patients with aortic valve disease after TAVI procedure.CONCLUSION: Age and kidney function determine the degree of anemia. The anisocytosis of red blood cells in anemic patients supplements prognostic information in addition to that derived from the WHO-based definition of anemia.展开更多
This paper probes into the feasibility of equilibrating pressure of water distribution network through (using auto-control valves) in theory and in the economy. An optimal valve control model is designed to minimize t...This paper probes into the feasibility of equilibrating pressure of water distribution network through (using auto-control valves) in theory and in the economy. An optimal valve control model is designed to minimize the sum of squares of residual pressure in the network. Such an analog simulation has been performed on the year 2003 programming network of a certain littoral district in North China, through which this paper confirms that it is feasible to equilibrate pressure with auto-control valves in theory. The research work has brought about a discovery of applicable conditions of valves in economic feasibility, which avoids a great economic loss due to the wild use of auto-control valve. In addition, simulated annealing algorithm is applied to optimize valve settings and shown to identify global optimum or near-optimum.展开更多
Energy consumed by distribution valves causes an energy loss for the output energy of hydraulic breakers, which has a significant influence on its efficiency. A new type of distribution valve used for hydraulic breake...Energy consumed by distribution valves causes an energy loss for the output energy of hydraulic breakers, which has a significant influence on its efficiency. A new type of distribution valve used for hydraulic breakers, de- signed to reduce energy consumption, is analyzed on the basis of the operating principle and energy loss of the current distribution valve. The new distribution valve adopts a cone valve and the optimization technique of unequal open de- gree for the valve port. Theoretical calculations and analyses have proven that the new distribution valve can reduce en- ergy loss by 9.0127J, or energy consumption by 31%, during an impact cycle and the efficiency of the hydraulic breaker can be raised by 4.5%. It has the following characteristics: little leakage, little pressure loss and low energy consump- tion.展开更多
A high-voltage optoelectronic probe is developed for measuring impulse voltage distribution along thyristor units in the HVDC converter valve.The dimension of the resistive voltage divider is optimized by means of num...A high-voltage optoelectronic probe is developed for measuring impulse voltage distribution along thyristor units in the HVDC converter valve.The dimension of the resistive voltage divider is optimized by means of numerical computation of electric field.A pulse frequency modulation(PFM) mode is adopted for the data transmission link because of its immunity to high-intensity electromagnetic interference.Experimental results indicate that the linearity deviation for the whole measuring system is within ±0.15%,and therefore it can meet requirements specified by IEC60700-1.展开更多
The paper deals with the simulation and the experimental verification of the hydraulic behavior of an electro-hydraulic load-sensing proportional control valve. An innovative CAE (computer aided engineering) methodo...The paper deals with the simulation and the experimental verification of the hydraulic behavior of an electro-hydraulic load-sensing proportional control valve. An innovative CAE (computer aided engineering) methodology, developed combining CFD (computational fluid dynamics) simulations with lumped and distributed numerical modeling, is firstly introduced and tailored by comparing the numerical results with measurements coming from an experimental campaign performed for a wide range of pressure loads and metered flow rates. Then, both the reliability and the limits of the numerical approach are highlighted through a detailed numerical vs. experimental comparison, involving the pressure of the main hydraulic lines, the flow rate through the first section and the local compensator displacement. Finally, the CAE methodology has been applied for assessing the internal ducts hydraulic permeability and the local compensator spring pre-load influence on the control valve metering curves. At the end of this analysis, an optimized design configuration, featuring a maximum controlled volumetric flow rate increased of more than 25%, has been proposed.展开更多
In this paper,several properties of one-way classification model with skew-normal random effects are obtained,such as moment generating function,density function and noncentral skew chi-square distribution,etc.Based o...In this paper,several properties of one-way classification model with skew-normal random effects are obtained,such as moment generating function,density function and noncentral skew chi-square distribution,etc.Based on the EM algorithm,we discuss the maximum likelihood(ML)estimation of unknown parameters.For testing problem of fixed effect,a parametric bootstrap(PB)approach is developed.Finally,some simulation results on the Type I error rates and powers of the PB approach are obtained,which show that the PB approach provides satisfactory performances on the Type I error rates and powers,even for small samples.For illustration,our main results are applied to a real data problem.展开更多
Pilot two-stage proportional valves are widely used in high-power hydraulic systems. For the purpose of improving the dynamic performance, reliability, and digitization of the traditional proportional valve, a novel t...Pilot two-stage proportional valves are widely used in high-power hydraulic systems. For the purpose of improving the dynamic performance, reliability, and digitization of the traditional proportional valve, a novel two-stage proportional valve with a pilot digital flow distribution is proposed from the viewpoint of the dual nozzle-flapper valve’s working principle. In particular, the dual nozzle-flapper is decoupled by two high-speed on/off valves (HSVs). First, the working principle and mathematical model of the proposed valve are determined. Then, the influences of the control parameters (duty cycle and switching frequency) and structural parameters (fixed orifice’s diameter and main valve’s spring) on the main valve’s motion are analyzed on the basis of theory, simulation, and experiment. In addition, in optimizing the value of the fixed orifice’s diameter, a new design criterion that considers the maximum pressure sensitivity, flow controllability, and flow linearization is proposed to improve the balance between the effective displacement and the displacement fluctuation of the main valve. The new scheme is verified by simulations and experiments. Experimental results of the closed-loop displacement tracking have demonstrated that the delay time of the main valve is always within 3.5 ms under different working conditions, and the tracking error can be significantly reduced using the higher switching frequency. The amplitude–frequency experiments indicate that a −3 dB-frequency of the proposed valve can reach 9.5 Hz in the case of ±50% full scale and 15 Hz in the case of 0%–50% full scale. The values can be further improved by increasing the flow rate of the pilot HSV.展开更多
To understand any statistical tool requires not only an understanding of the relevant computational procedures but also an awareness of the assumptions upon which the procedures are based, and the effects of violation...To understand any statistical tool requires not only an understanding of the relevant computational procedures but also an awareness of the assumptions upon which the procedures are based, and the effects of violations of these assumptions. In our earlier articles (Laverty, Miket, & Kelly [1]) and (Laverty & Kelly, [2] [3]) we used Microsoft Excel to simulate both a Hidden Markov model and heteroskedastic models showing different realizations of these models and the performance of the techniques for identifying the underlying hidden states using simulated data. The advantage of using Excel is that the simulations are regenerated when the spreadsheet is recalculated allowing the user to observe the performance of the statistical technique under different realizations of the data. In this article we will show how to use Excel to generate data from a one-way ANOVA (Analysis of Variance) model and how the statistical methods behave both when the fundamental assumptions of the model hold and when these assumptions are violated. The purpose of this article is to provide tools for individuals to gain an intuitive understanding of these violations using this readily available program.展开更多
基金supported by Major military logistics research pro-jects(AWS13Z006)National Key Research and Development program of China(2017YFC0806404).
文摘In this work,a six-bed pressure swing adsorption(PSA)process was investigated to produce medical oxygen from air,which uses the combination of six-way rotating distribution valve and PSA and has the main advantage of effectively saving space compared to the traditional two-bed or four-bed PSA process and can obtain greater productivity.The mathematical model of adsorption beds was developed based on the separation mechanism and the interaction among different equipment.Moreover,a pilot-scale device has been constructed to verify the accuracy of mathematical model by experiment.The oxygen product conformed to the medical standard(>93%(vol))with a recovery of over 57%.Some related parameters were also discussed in detail,such as step time,ratio of length to the diameter,flow rate of product.
文摘Water distribution network(WDN)leakage management has received increased attention in recent years.One of the most successful leakage-control strategies is to divide the network into District Metered Areas(DMAs).As a multi-staged technique,the generation of DMAs is a difficult task in design and implementation(i.e.,clustering,sectorization,and performance evaluation).Previous studies on DMAs implementation did not consider the potential use of existing valves in achieving the objective.In this work,a methodology is proposed for detecting clusters and reducing the cost of additional valves and DMA sectorization by considering existing valves as much as possible.The procedure of DMAs identification has been divided into three stages,i.e.,a)clusters identification;b)sectorization or boundaries optimization and c)performance evaluation of the partitioned network.The proposed methodology is evaluated on a simple network and a real-world water network with the findings provided and compared to the DMAs,established for a raw water network with no existing valves.It is found that there is an adequate difference in cost of strategy implementation in both the cases for the network under consideration and the existing valve system achieved better network performance in terms of resilience index.
文摘AIM: To determine the impact of red blood cell distribution width on outcome in anemic patients undergoing transcatheter aortic valve implantation(TAVI).METHODS: In a retrospective single center cohort study we determined the impact of baseline red cell distribution width(RDW) and anemia on outcome in 376 patients with aortic stenosis undergoing TAVI. All patients were discussed in the institutional heart team and declined for surgical aortic valve replacement due to high operative risk. Collected data included patient characteristics, imaging findings, periprocedural in hospital data, laboratory results and follow up data. Blood samples for hematology and biochemistry analysis were taken from every patient before and at fixed intervals up to 72 h after TAVI including blood count and creatinine. Descriptive statistics were used for patient's characteristics. KaplanMeier survival curves were used for time to event outcomes. A recursive partitioning regression and classification was used to investigate the association between potential risk factors and outcome variables.RESULTS: Mean age in our study population was 81 ± 6.1 years. Anemia was prevalent in 63.6%(n = 239) of our patients. Age and creatinine were identified as risk factors for anemia. In our study population, anemia per se did influence 30-d mortality but did not predict longterm mortality. In contrast, a RDW > 14% showed to be highly predictable for a reduced short- and longterm survival in patients with aortic valve disease after TAVI procedure.CONCLUSION: Age and kidney function determine the degree of anemia. The anisocytosis of red blood cells in anemic patients supplements prognostic information in addition to that derived from the WHO-based definition of anemia.
文摘This paper probes into the feasibility of equilibrating pressure of water distribution network through (using auto-control valves) in theory and in the economy. An optimal valve control model is designed to minimize the sum of squares of residual pressure in the network. Such an analog simulation has been performed on the year 2003 programming network of a certain littoral district in North China, through which this paper confirms that it is feasible to equilibrate pressure with auto-control valves in theory. The research work has brought about a discovery of applicable conditions of valves in economic feasibility, which avoids a great economic loss due to the wild use of auto-control valve. In addition, simulated annealing algorithm is applied to optimize valve settings and shown to identify global optimum or near-optimum.
基金Project 50374071 supported by National Natural Science Foundation of China
文摘Energy consumed by distribution valves causes an energy loss for the output energy of hydraulic breakers, which has a significant influence on its efficiency. A new type of distribution valve used for hydraulic breakers, de- signed to reduce energy consumption, is analyzed on the basis of the operating principle and energy loss of the current distribution valve. The new distribution valve adopts a cone valve and the optimization technique of unequal open de- gree for the valve port. Theoretical calculations and analyses have proven that the new distribution valve can reduce en- ergy loss by 9.0127J, or energy consumption by 31%, during an impact cycle and the efficiency of the hydraulic breaker can be raised by 4.5%. It has the following characteristics: little leakage, little pressure loss and low energy consump- tion.
文摘A high-voltage optoelectronic probe is developed for measuring impulse voltage distribution along thyristor units in the HVDC converter valve.The dimension of the resistive voltage divider is optimized by means of numerical computation of electric field.A pulse frequency modulation(PFM) mode is adopted for the data transmission link because of its immunity to high-intensity electromagnetic interference.Experimental results indicate that the linearity deviation for the whole measuring system is within ±0.15%,and therefore it can meet requirements specified by IEC60700-1.
文摘The paper deals with the simulation and the experimental verification of the hydraulic behavior of an electro-hydraulic load-sensing proportional control valve. An innovative CAE (computer aided engineering) methodology, developed combining CFD (computational fluid dynamics) simulations with lumped and distributed numerical modeling, is firstly introduced and tailored by comparing the numerical results with measurements coming from an experimental campaign performed for a wide range of pressure loads and metered flow rates. Then, both the reliability and the limits of the numerical approach are highlighted through a detailed numerical vs. experimental comparison, involving the pressure of the main hydraulic lines, the flow rate through the first section and the local compensator displacement. Finally, the CAE methodology has been applied for assessing the internal ducts hydraulic permeability and the local compensator spring pre-load influence on the control valve metering curves. At the end of this analysis, an optimized design configuration, featuring a maximum controlled volumetric flow rate increased of more than 25%, has been proposed.
基金Supported by Zhejiang Provincial Philosophy and Social Science Planning Zhijiang Youth Project of China(Grant No.16ZJQN017YB)Ministry of Education of China,Humanities and Social Science Projects(Grant No.19YJA910006)+2 种基金Zhejiang Provincial Natural Science Foundation of China(Grant No.LY20A010019)Fundamental Research Funds for the Provincial Universities of Zhejiang(Grant No.GK199900299012-204)Zhejiang Provincial Statistical Science Research Base Project of China(Grant No.19TJJD08)
文摘In this paper,several properties of one-way classification model with skew-normal random effects are obtained,such as moment generating function,density function and noncentral skew chi-square distribution,etc.Based on the EM algorithm,we discuss the maximum likelihood(ML)estimation of unknown parameters.For testing problem of fixed effect,a parametric bootstrap(PB)approach is developed.Finally,some simulation results on the Type I error rates and powers of the PB approach are obtained,which show that the PB approach provides satisfactory performances on the Type I error rates and powers,even for small samples.For illustration,our main results are applied to a real data problem.
基金This work was supported by the National Natural Science Foundation of China(Grant No.51975275)the National Key Laboratory of Science and Technology on Helicopter Transmission(Nanjing University of Aeronautics and Astronautics),China(Grant No.HTL-A-20G02)the Postgraduate Research and Practice Innovation Program of Jiangsu Province,China(Grant No.KYCX200178).
文摘Pilot two-stage proportional valves are widely used in high-power hydraulic systems. For the purpose of improving the dynamic performance, reliability, and digitization of the traditional proportional valve, a novel two-stage proportional valve with a pilot digital flow distribution is proposed from the viewpoint of the dual nozzle-flapper valve’s working principle. In particular, the dual nozzle-flapper is decoupled by two high-speed on/off valves (HSVs). First, the working principle and mathematical model of the proposed valve are determined. Then, the influences of the control parameters (duty cycle and switching frequency) and structural parameters (fixed orifice’s diameter and main valve’s spring) on the main valve’s motion are analyzed on the basis of theory, simulation, and experiment. In addition, in optimizing the value of the fixed orifice’s diameter, a new design criterion that considers the maximum pressure sensitivity, flow controllability, and flow linearization is proposed to improve the balance between the effective displacement and the displacement fluctuation of the main valve. The new scheme is verified by simulations and experiments. Experimental results of the closed-loop displacement tracking have demonstrated that the delay time of the main valve is always within 3.5 ms under different working conditions, and the tracking error can be significantly reduced using the higher switching frequency. The amplitude–frequency experiments indicate that a −3 dB-frequency of the proposed valve can reach 9.5 Hz in the case of ±50% full scale and 15 Hz in the case of 0%–50% full scale. The values can be further improved by increasing the flow rate of the pilot HSV.
文摘To understand any statistical tool requires not only an understanding of the relevant computational procedures but also an awareness of the assumptions upon which the procedures are based, and the effects of violations of these assumptions. In our earlier articles (Laverty, Miket, & Kelly [1]) and (Laverty & Kelly, [2] [3]) we used Microsoft Excel to simulate both a Hidden Markov model and heteroskedastic models showing different realizations of these models and the performance of the techniques for identifying the underlying hidden states using simulated data. The advantage of using Excel is that the simulations are regenerated when the spreadsheet is recalculated allowing the user to observe the performance of the statistical technique under different realizations of the data. In this article we will show how to use Excel to generate data from a one-way ANOVA (Analysis of Variance) model and how the statistical methods behave both when the fundamental assumptions of the model hold and when these assumptions are violated. The purpose of this article is to provide tools for individuals to gain an intuitive understanding of these violations using this readily available program.