Nine C2-symmetric chiral disulfonamldes were designed and synthesized from L-valine, L-phenylalanine and L-leucine respectively via one-pot ring opening of aziridines. The application of these disulfonamides as cataly...Nine C2-symmetric chiral disulfonamldes were designed and synthesized from L-valine, L-phenylalanine and L-leucine respectively via one-pot ring opening of aziridines. The application of these disulfonamides as catalyst in the addition of diethyl zinc to benzaldehyde in three reagent systems: Ligand-Ti(OiPr)4-Et2Zn; Ligand-Ti(OiPr)4-H2O-Et2Zn; Ligand-Et2Zn was also described.展开更多
文摘Nine C2-symmetric chiral disulfonamldes were designed and synthesized from L-valine, L-phenylalanine and L-leucine respectively via one-pot ring opening of aziridines. The application of these disulfonamides as catalyst in the addition of diethyl zinc to benzaldehyde in three reagent systems: Ligand-Ti(OiPr)4-Et2Zn; Ligand-Ti(OiPr)4-H2O-Et2Zn; Ligand-Et2Zn was also described.
