Hypothemycin production and its derivatives diversifying of <i>Aigialus parvus</i>BCC 5311 influenced by cultural condition

Many metabolites produced by various microorganisms have proven their usefulness in the area concerning human health. However, most of their diverse natural compound biosyntheses are hardly discovered. These metabolites might have specific or novel functions and these diverse active compounds can be achieved by biosynthesis, semi-biosynthesis, or chemical synthesis. A strategy to exploit the biosynthesis potential of a fungal strain is to use various culture conditions and to evaluate the chemical profiles of the culture extracts. The value of this approach was demonstrated with the fungal strain Aigialus parvus BCC 5311, producer of hypothemycin, aigialospirol, and aigialomycin A-D. The optimization of hypothemycin production and its derivative diversity by Aigialus parvus BCC 5311 was carried out using qualitative (general factorial design) and quantitative analysis (two-level fractional factorial design). Qualitative analysis revealed that soluble starch and yeast extract were shown to be the best carbon and nitrogen source respectively for the production of hypothemycin, aigialospirol and aigialomycin A-D. Quantitative analysis showed that the initial pH of culture medium is the most important factor that affects the production of hypothemycin and its derivatives (aigialospirol and aigialomycin A-D) production. Optimal medium composition used in a 5 L bioreactor generated a specific growth rate of A. parvus BCC 5311 of 0.0295 h-1, biomass yield of 1.6 g×gstarch-1, hypothemycin yield of 13.6 mg×gbiomass-1, and hypothemycin production rate of 0.6 mg×L-1×day-1. The maximum concentration of 58.0 mg×L-1 of hypothemycin was obtained at 120 h of culturing. Furthermore, the Aigialomycin A-D and Aigialospirol obtained were diversified towards various cultural conditions used. The high amount of hypothemycin produced and the diversity of derivatives obtained from this study should be useful for future mass production.

Approach in A People-Oriented and Diversifying Way——Exclusive Interview with Professor Wu Guangjun, Dean of SELLC, BISU

This autumn fruitful autumn,Beijing International Studies University(BISU)is about to celebrate the54th anniversary since its foundation.Meanwhile,the Department of English established in1964turned into the School of English Language,Literature and Culture(SELLC)in2009.Are there any moving stories behind these name-changes,and did the teaching philosophy change accordingly?

A Review of Contact Electrification at Diversified Interfaces and Related Applications on Triboelectric Nanogenerator

The triboelectric nanogenerator(TENG)can effectively collect energy based on contact electrification(CE)at diverse interfaces,including solid–solid,liquid–solid,liquid–liquid,gas–solid,and gas–liquid.This enables energy harvesting from sources such as water,wind,and sound.In this review,we provide an overview of the coexistence of electron and ion transfer in the CE process.We elucidate the diverse dominant mechanisms observed at different interfaces and emphasize the interconnectedness and complementary nature of interface studies.The review also offers a comprehensive summary of the factors influencing charge transfer and the advancements in interfacial modification techniques.Additionally,we highlight the wide range of applications stemming from the distinctive characteristics of charge transfer at various interfaces.Finally,this review elucidates the future opportunities and challenges that interface CE may encounter.We anticipate that this review can offer valuable insights for future research on interface CE and facilitate the continued development and industrialization of TENG.

Co-incorporating green manure and crop straw increases crop productivity and improves soil quality with low greenhouse-gas emissions in a crop rotation

In a nine-year field experiment in a wheat-maize-sunflower cropping system in Hetao Irrigation Area,Inner Mongolia,China,organic amendments applied as straw,manure,green manure,and the combination of green manure and straw increased wheat and maize yield,soil aggregate stability,and soil microbial activity in comparison with chemical fertilizer,without changing greenhouse gas emission intensity.

Design of Diversified Intelligent Control System for Energy-saving Optimization of Solar Greenhouse in North China

Intelligent greenhouse can promote the development of modern agriculture, realize the high quality and high yield of crops, and also bring greater economic benefits. In accordance with the climate conditions in northwest China, a set of intelligent control system for diversified environment of solar greenhouse was designed. The system divides the annual greenhouse control into six stages according to the optimal energy saving. It uses modern detection technology to collect the greenhouse environmental temperature, environmental humidity, soil humidity, CO_(2) concentration and illumination parameters under different working modes. It uses programmable logic control technology to realize the data processing of various parameters and the action control of rolling film, wet curtain fan and other actuators. It uses KingView monitoring software to realize the monitoring and manual control of greenhouse environment parameters. The operation results indicate that the control system runs stably and basically meets the control requirements.

Diversified Teaching Method in Basic Piano Course Instruction for Higher Education Teachers

Diversified teaching plays an important role in the sustainable development of China’s basic piano course instruction for higher education teachers.A diversified curriculum system should be designed to promote the development of each student,and efforts should be made to cultivate high-quality talents who can adapt to the various needs of the society as well as to promote the reform and development of basic piano course instruction for higher education teachers.The aim of this study was to explore the teaching of basic piano course for higher education teachers based on the diversified teaching method.The teaching methods use for basic piano course were analyzed in this study,and two research methods were used to carry out the present study so as to effectively improve the operation of the diversified teaching method.Through a survey of the current situation of piano instruction in two higher education faculties,we can see that the teaching of basic piano course in higher education is still dominated by the traditional teaching method although the majority of students preferred the diversified teaching method.

上海联创国际设计谷,上海,中国

原建筑是一座已经老朽的宾馆建筑,设计目标是希望通过把宾馆改造成一个能够满足日益多元的使用需求的创意设计园区,即通过功能置换型的改造与再生以及创新材料与技术的应用,为建筑注入新的活力,为衰败的城市机体注入新的生机。

Species-diversified plant cover enhances orchard ecosystem resistance to climatic stress and soil erosion in subtropical hillside

Naturally occurring plants in agroecosystem evidently play an important role in ecosystem stability. Field studies on the ecological effects of native plants conserved in orchard and their resistance to adverse climatic stress, and soil erosion were conducted from 1998 to 2001 in a newly developed Changshan-huyou (Citrus changshan-huyou Y.B. Chang) orchard. The experimental area covered 150 ha in typical red soil hilly region in southeastern China. The experimental design was a randomized complete block with six combinations of twelve plant species with four replications. All species used were native in the orchard. Plots were 15×8m^2 and separated by 2m buffer strips. Precipitation, soil erosion in rainstorm days and aboveground biomass of plant community when rainstorm days ended, soil temperature and moisture under various plant covers during seasonal megathermal drought period, antiscourability of soil with different root density under various simulated rainfalls were measured. Plant cover significantly decreased the daily highest and mean soil temperature and its daily variation in hot-drought season, but there was no significant difference of the alleviation among various plant covers. Plant covers significantly increased the soil moisture in seasonal megathermal drought period. Better moisture maintenance and soil erosion reduction was found when the plant species numbers in cover plant communities increased from one to eight. Higher root density in plant communities with higher species richness increased significantly the antiscourability of the soil. It was suggested that conserving plant communities with diversified native species could produce the best positive ecological effects on citrus orchard ecosystem stability.

Thoughts on Development of Green Agriculture and Green Economy——Based on the Survey of Farms in Qinhuangdao

Based on the concept and development process of green agriculture and green economy,the field survey and questionnaire investigation were carried out in Jincheng Specialized Planting Cooperative in Xinji Town,Changli County of Qinhuangdao City. The results show that there are still many problems in the development of green economy and the improvement of green farms in Hebei Province. On this basis,it came up with pertinent measures and recommendations,in the hope of providing theoretical basis and reference for establishment and development of green farms in Hebei Province and most of domestic areas.

Confucian Human Rights Ideas and Their Influence on Modern Human Rights Thought

The world in which we are now living is becoming economically globalized, politically multi-polarized and culturally diversified. In such a global trend, the discussion on oriental culture and human rights development aims at stimulating Chinese and international human rights development, promoting China’s human rights exchanges and cooperation with the theme of peace and development. This is of theoretical and practical importance.

Satellite E2E Network Slicing Based on 5G Technology

We investigate the design of satellite network slicing for the first time to provide customized services for the diversified applications,and propose a novel scheme for satellite end-to-end(E2E) network slicing based on 5G technology,which provides a view of common satellite network slicing and supports flexible network deployment between the satellite and the ground.Specifically,considering the limited satellite network resource and the characteristics of the satellite channel,we propose a novel satellite E2E network slicing architecture.Therein,the deployment of the network functions between the satellite and the ground is coordinately considered.Subsequently,the classification and the isolation technologies of satellite network sub-slices are proposed adaptively based on 5G technology to support resource allocation on demand.Then,we develop the management technologies for the satellite E2E network slicing including slicing key performance indicator(KPI) design,slicing deployment,and slicing management.Finally,the analysis of the challenges and future work shows the potential research in the future.

Diversified Teaching Methods in Nursing:Using Animal Experimentation to Promote Core Professional Competencies in Basic Nursing Training

Objective： The aim of this project was to train highly professional and specialized nursing students from medical colleges to adapt to bedside clinical care by exploring and discussing various methods of injection and IV infusion in animal experimentation to hone the core professional nursing competencies. Methods： Two classes from the 2012 senior graduating nursing class were randomly selected by a computer to conduct the diversified practical teaching methods based on animal experimentation. A hospital environment was simulated by requiring students to perform different types of injections and practical IV infusion techniques. A comprehensive evaluation of the core professional competencies, as well as other integrated competencies, was conducted to determine the effectiveness of the teaching methods. Results： Two-sampled, pairwise u-tests were performed between the scores of the experimental （nursing class 2） and control （nursing class 1） groups. These findings showed that the overall test scores were significantly higher in the experimental group compared to the control group and that the average P-values for the competencies in various categories were 〈0.01, which indicated statistically significant results. Conclusions： Based on the data from this project, diversified teaching methods for basic nursing training founded on animal experimentation can help nursing students perfect their core professional competencies and improve their overall professional standing. The introduction of animal experimentation requires further verification, and an increased acknowledgement of its benefits through the widespread dissemination of this information.

Editorial: Special issue on marine instruments

Our blue planet is made of atmosphere,hydrosphere,lithosphere and biosphere,these four layers are interdependence and interaction,which effect the environment and life on the planet.In these four layers,the hydrosphere is mainly associated with the ocean which is crucial to the human survival and development,due to the difference heat capacities be-

On the Relationship between China and the International Energy Agency

As China needs to play a more active role in global energy governance, it must create a diversified, multi-level system to enhance energy security and to alleviate environmental pressures. A China-IEA bilateral relationship exists under an Association Initiative, but a stronger bond is needed. Though it is not an IEA member, China's massive energy needs makes it sensible that the two sides overcome existing obstacles that include OECD membership, statistical information issues and energy autonomy. In this regard an "IEA+China" might be a feasible model.

Flexible Internet for Sustainable Evolution

Over the past 30 years,the Internet has grown into a truly worldwide open infrastructure for information,communication and commerce,which has revolutionized our society.Nevertheless,the lack of adaptability along with diversified applications makes Internet difficult to provide corresponding services efficiently including convergence,universality,quality of service,expansibility,mobility,and so on.At the same time,

PRESENT SITUATION OF CHINESE ACUPUNCTURE AND MOXIBUSTION EDUCATION AND ITS PROSPECTIVE STRATEGY

PRESENT SITUATION OFCHINESE ACUPUNCTURE ANDMOXIBUSTION EDUCATIONThe science of acupuncture andmoxibustion(Acup-Moxi)is an importantbranch of Traditional Chinese Medicine(TCM).Likewise,Acup-Moxi eudcation

剖析近五年江苏高考任务型阅读——谈高中英语课文教学改革与习题设计的多样化

自从江苏高考英语考查任务型阅读以来,已经五年过去了。其中,任务型阅读的考查特别重视学生＂综合语言应用能力＂的培养,＂着重提高学生用英语获取信息、处理信息、分析问题和解决问题的能力＂,＂注重发展学生用英语进行思维和表达的能力＂,体现了高中英语课程和课标教材采用的＂任务型＂教学途径。剖析这五年来任务型阅读的考查特点、考点类型、考查方法,在牛津英语课文教学和练习设计方面应该进行一些改革与创新。

ISSUES ON CHINA′S ENERGY SECURITY

For many years, China has made great strides in constructing a sizeable and stable energy supply system rooted mainly in domestic coal supply. That system, however, is subject to immense strain as a result of rapid economic growth, rising living standard, widespread environmental degradation, limited oil reserves and uneven resources distribution. Industrialization and urbanization since the early 1980s have imposed structural constraints on its traditional coal-based energy supply model. Eventually, China became a net oil-importer in 1993 when ten million tons of crude oil and petroleum products from abroad fed into the local economies of the coastal areas. Such a change meant that energy security has become an increasingly sensitive issue to the central government of China. This paper argues that China could benefit from a more open energy supply by striking to a balance of both domestic and international sources, rather than the traditional mode emphasized on a highly self-sufficiency rate.

The Formulation of Water System Planning of Jingdezhen Under Diversified Needs

The water system is the basic condition for urban development, and a key resource and environmental carrier in the process of urban formation. It has an important restrictive effect on the survival of the city. Based on the diversified needs of urban water system development, this paper explores the preparation of the urban water system planning of Jingdezhen, strengthens the protection of water system and environmental quality, and explores urban cultural connotation, in order to build a unique urban water environment.