合环电流评估技术对于配电网馈线合环转供电操作具有重要意义,为了提高主动配电网馈线合环电流计算的准确性,文中从融入源荷数据分布特性及预测的角度,提出基于双重K2算法和概率潮流(double K2 algorithm and probability load flow,DK2...合环电流评估技术对于配电网馈线合环转供电操作具有重要意义,为了提高主动配电网馈线合环电流计算的准确性,文中从融入源荷数据分布特性及预测的角度,提出基于双重K2算法和概率潮流(double K2 algorithm and probability load flow,DK2-PLF)的主动配电网馈线合环电流评估方法。首先,采用基于DK2算法的贝叶斯网络描述源荷相关性样本;其次,利用Cholesky分解方法处理获得的源荷相关性样本,以半不变量法计算主动配电网馈线合环电流的累积概率分布;然后,对主动配电网馈线合环电流从合环成功率和越限程度两方面进行安全性评估;最后,以贵州某城市为算例,对10 kV配电网系统开展馈线合环电流评估研究。得出以下结论:一是从概率密度、累积分布、最大误差三方面比较,相比于K2算法,DK2算法源荷预测值的概率密度、累积分布误差较小,验证了DK2算法的优越性;二是从累积分布、最大误差两方面比较,采用Cholesky分解的半不变量法对比未采用Cholesky分解的半不变量法、蒙特卡洛法,其累积分布误差较小,采用Cholesky分解的半不变量法满足主动配电网馈线合环电流评估要求;三是从合环成功率、合环越限程度两方面比较,采用半不变量法计算的合环电流安全性指标结果与仿真结果偏差在电网经验误差5%范围内,说明基于DK2-PLF的主动配电网馈线合环电流评估方法可为合环辅助决策提供参考。展开更多
The effects of DK2,a peroxisome proliferator-activated receptor γ agonist,on cultured human pterygium fibroblasts (HPFs) in virto were studied.The HPFs were incubated with 0-200 μmol/L DK2 for 12-72 h.The MTT method...The effects of DK2,a peroxisome proliferator-activated receptor γ agonist,on cultured human pterygium fibroblasts (HPFs) in virto were studied.The HPFs were incubated with 0-200 μmol/L DK2 for 12-72 h.The MTT method was used to assay the bio-activity of DK2 at different doses and time.The cytotoxic effect of DK2 was measured by LDH release assay.The cell cycle distribution and apoptosis were flow cytometrically detected.The expression of proliferating cell nuclear antigen (PCNA) in each group was detected by real-time PCR (RT-PCR) and Western blotting.The results showed that administration of 1-75 μmol/L DK2 for 12-72 h could significantly inhibit HPF proliferation in a dose-and time-dependent manner.DK2-treated cells did not release significant amount of LDH as compared with rosiglitazone-treated cells.After treatment with DK2 at concentrations of 15,25 μmol/L for 24 h,the number of HPFs in G 0 /G 1 phase was significantly increased while that in S phase was significantly decreased (P【0.05),leading to arrest at G 0 /G 1 phase.The apoptosis rates of HPF cells in drug-treated groups were significantly higher than the rate of control group (P【0.05).At the dosage range between 15-25 μmol/L,DK2 could inhibit the expression of PCNA mRNA and protein in HPFs in a dose-dependent fashion (P【0.05).It was concluded that PPARγ agonist can significantly inhibit HPF proliferation,resulting in the arrest at G 0 /G 1 phase,induce the apoptosis of HPFs,and suppress the synthesis of PCNA,in dose-and time-dependent manners.展开更多
文摘合环电流评估技术对于配电网馈线合环转供电操作具有重要意义,为了提高主动配电网馈线合环电流计算的准确性,文中从融入源荷数据分布特性及预测的角度,提出基于双重K2算法和概率潮流(double K2 algorithm and probability load flow,DK2-PLF)的主动配电网馈线合环电流评估方法。首先,采用基于DK2算法的贝叶斯网络描述源荷相关性样本;其次,利用Cholesky分解方法处理获得的源荷相关性样本,以半不变量法计算主动配电网馈线合环电流的累积概率分布;然后,对主动配电网馈线合环电流从合环成功率和越限程度两方面进行安全性评估;最后,以贵州某城市为算例,对10 kV配电网系统开展馈线合环电流评估研究。得出以下结论:一是从概率密度、累积分布、最大误差三方面比较,相比于K2算法,DK2算法源荷预测值的概率密度、累积分布误差较小,验证了DK2算法的优越性;二是从累积分布、最大误差两方面比较,采用Cholesky分解的半不变量法对比未采用Cholesky分解的半不变量法、蒙特卡洛法,其累积分布误差较小,采用Cholesky分解的半不变量法满足主动配电网馈线合环电流评估要求;三是从合环成功率、合环越限程度两方面比较,采用半不变量法计算的合环电流安全性指标结果与仿真结果偏差在电网经验误差5%范围内,说明基于DK2-PLF的主动配电网馈线合环电流评估方法可为合环辅助决策提供参考。
基金supported by a grant from the Natural Sciences Foundation of Hubei Province,China(No.2008CDA055)
文摘The effects of DK2,a peroxisome proliferator-activated receptor γ agonist,on cultured human pterygium fibroblasts (HPFs) in virto were studied.The HPFs were incubated with 0-200 μmol/L DK2 for 12-72 h.The MTT method was used to assay the bio-activity of DK2 at different doses and time.The cytotoxic effect of DK2 was measured by LDH release assay.The cell cycle distribution and apoptosis were flow cytometrically detected.The expression of proliferating cell nuclear antigen (PCNA) in each group was detected by real-time PCR (RT-PCR) and Western blotting.The results showed that administration of 1-75 μmol/L DK2 for 12-72 h could significantly inhibit HPF proliferation in a dose-and time-dependent manner.DK2-treated cells did not release significant amount of LDH as compared with rosiglitazone-treated cells.After treatment with DK2 at concentrations of 15,25 μmol/L for 24 h,the number of HPFs in G 0 /G 1 phase was significantly increased while that in S phase was significantly decreased (P【0.05),leading to arrest at G 0 /G 1 phase.The apoptosis rates of HPF cells in drug-treated groups were significantly higher than the rate of control group (P【0.05).At the dosage range between 15-25 μmol/L,DK2 could inhibit the expression of PCNA mRNA and protein in HPFs in a dose-dependent fashion (P【0.05).It was concluded that PPARγ agonist can significantly inhibit HPF proliferation,resulting in the arrest at G 0 /G 1 phase,induce the apoptosis of HPFs,and suppress the synthesis of PCNA,in dose-and time-dependent manners.
