OBJECTIVE:To evaluate the effect of acupuncture on the quality of life in patients with depression by clinical randomized single-blind placebo-controlled study.METHODS:one hundred and sixty-three cases of depression a...OBJECTIVE:To evaluate the effect of acupuncture on the quality of life in patients with depression by clinical randomized single-blind placebo-controlled study.METHODS:one hundred and sixty-three cases of depression according with the inclusion criteria were randomly divided into a group of acupuncture dredging liver and regulating flow of theosophy(group 1),a group of acupoint shallow stab(group 2)and a group of non-acupoint shallow stab(group 3)at 1∶1∶1 ratio,and treated with acu-puncture,moxibustion,and intradermal embedding of needle,twice a week,for a total of 12 weeks.Scale of Quality of Life(SF-36)was used to measure the scores at four different time points and evaluate the effect of acupuncture on the quality of life of the patients with depression.RESULTS:At each time point after treatment,in scores of the 8 items,physical function,physical role,bodily pain,general physical condition,energy,social function,emotional function and mental health there were statistically significant differences among the 3 groups(P<0.0125).CONCLUSION:Acupuncture can effectively improve the quality of life of patients with depression.展开更多
Objective:By observing the differences in Western Ontario and McMaster Universities osteoarthritis index(WOMAC)and visual analog scale(VAS)scores in moxibustion treatment for moderate-to-severe primary knee osteoarthr...Objective:By observing the differences in Western Ontario and McMaster Universities osteoarthritis index(WOMAC)and visual analog scale(VAS)scores in moxibustion treatment for moderate-to-severe primary knee osteoarthritis(KOA)with moxa of different storage years(3-year moxa and 1-year moxa from Qichun,Huanggang City,Hubei Province,China)through a randomized clinical trial,to objectively evaluate the differences in therapeutic efficacy of moxibustion with moxa of different storage years.Methods:A total of 63 patients with moderate-to-severe KOA who met the inclusion criteria were randomized into moxibustion group 1 and moxibustion group 2 by central randomization method,with 32 cases in moxibustion group 1 and 31 cases in moxibustion group 2.Moxibustion group 1 was treated with moxa stored for 3 years,and moxibustion group 2 was treated with moxa stored for 1 year.Dubi(ST 35),Neixiyan(EX-LE 4)and Heding(EX-LE 2)were selected in both groups,and the treatment lasted 20 min per time,3 times a week.The immediate efficacy was compared after 6 times of treatment,and long-term efficacy was compared at follow-up 4 weeks after the end of treatment.Results:During the treatment,there were 2 dropouts in moxibustion group 1,and 1 dropout in moxibustion group 2.The total effective rate in the two groups was 83.3%and 60.0%,respectively.Followed up at 4 weeks after the end of treatment,the total effective rate in the two groups was 80.0%and 66.7%,respectively.There were no statistical differences between the two groups(both P>0.05).After treatment and 4 weeks after the end of treatment,the WOMAC and VAS scores in both groups decreased significantly compared with those before treatment(all P<0.01);the scores of stiffness item of WOMAC in moxibustion group 1 were lower than those in moxibustion group 2(both P<0.05);there were no statistical differences in the scores of pain item and dysfunction item of WOMAC,and VAS scores between the two groups(all P>0.05).Conclusion:Moxibustion with moxa of different storage years(stored for 3 years and 1 year)both can improve the pain,stiffness and motor function in patients with moderate-to-severe KOA.While moxa stored for 3 years has a better therapeutic efficacy in improving stiffness of the knee joint than that stored for 1 year.展开更多
基金Supported by the Youth Fund Project of Natural Science Foundation of China(Antidepressant Mechanism of Acupuncture Based on Snare Proteins Modulating the Release of Glutamic Acid in Presynaptic NeuronsNo.81303041)+5 种基金the China Postdoctoral Science Foundation(Mechanism Research of Acupuncture on Hippocampal Tripartite Glutamatergic Synapses of Depressive Disorder RatsNo.2012M511784)the Outstanding Young Innovation Foundation of Guangdong Provincial Department of Education(Clinical Research of Acupuncture in the Treatment of Mild to Moderate Depression,No.2012LYM0043)Special Research Foundation of New Teacher Category for the Doctor-al Program of Higher School of National Ministry of Education(the Moderating Effects of Acupuncture for Hippocampal Tripartite Glutamatergic Synapses of Depressive Disorder rats,No.20124425120005)the Special Financial Grant from the China Postdoctoral Science Foundation(the Modulating Effects of Acupuncture for Glutamic Acid in Hippocampal Presynaptic Neurons of Depressive Disorder Rats,No.2013T60793)the Science Foundation of the Postdoctoral Researchers in Guangzhou University of Chinese Medicine from Guangdong Provincial Department of Human Resources and Social Security(Clinical Study on Acupuncture and Moxibustion for Treatment of Depression Based on Patient Reported Outcome Indicators,No.BBK429122K19)
文摘OBJECTIVE:To evaluate the effect of acupuncture on the quality of life in patients with depression by clinical randomized single-blind placebo-controlled study.METHODS:one hundred and sixty-three cases of depression according with the inclusion criteria were randomly divided into a group of acupuncture dredging liver and regulating flow of theosophy(group 1),a group of acupoint shallow stab(group 2)and a group of non-acupoint shallow stab(group 3)at 1∶1∶1 ratio,and treated with acu-puncture,moxibustion,and intradermal embedding of needle,twice a week,for a total of 12 weeks.Scale of Quality of Life(SF-36)was used to measure the scores at four different time points and evaluate the effect of acupuncture on the quality of life of the patients with depression.RESULTS:At each time point after treatment,in scores of the 8 items,physical function,physical role,bodily pain,general physical condition,energy,social function,emotional function and mental health there were statistically significant differences among the 3 groups(P<0.0125).CONCLUSION:Acupuncture can effectively improve the quality of life of patients with depression.
文摘Objective:By observing the differences in Western Ontario and McMaster Universities osteoarthritis index(WOMAC)and visual analog scale(VAS)scores in moxibustion treatment for moderate-to-severe primary knee osteoarthritis(KOA)with moxa of different storage years(3-year moxa and 1-year moxa from Qichun,Huanggang City,Hubei Province,China)through a randomized clinical trial,to objectively evaluate the differences in therapeutic efficacy of moxibustion with moxa of different storage years.Methods:A total of 63 patients with moderate-to-severe KOA who met the inclusion criteria were randomized into moxibustion group 1 and moxibustion group 2 by central randomization method,with 32 cases in moxibustion group 1 and 31 cases in moxibustion group 2.Moxibustion group 1 was treated with moxa stored for 3 years,and moxibustion group 2 was treated with moxa stored for 1 year.Dubi(ST 35),Neixiyan(EX-LE 4)and Heding(EX-LE 2)were selected in both groups,and the treatment lasted 20 min per time,3 times a week.The immediate efficacy was compared after 6 times of treatment,and long-term efficacy was compared at follow-up 4 weeks after the end of treatment.Results:During the treatment,there were 2 dropouts in moxibustion group 1,and 1 dropout in moxibustion group 2.The total effective rate in the two groups was 83.3%and 60.0%,respectively.Followed up at 4 weeks after the end of treatment,the total effective rate in the two groups was 80.0%and 66.7%,respectively.There were no statistical differences between the two groups(both P>0.05).After treatment and 4 weeks after the end of treatment,the WOMAC and VAS scores in both groups decreased significantly compared with those before treatment(all P<0.01);the scores of stiffness item of WOMAC in moxibustion group 1 were lower than those in moxibustion group 2(both P<0.05);there were no statistical differences in the scores of pain item and dysfunction item of WOMAC,and VAS scores between the two groups(all P>0.05).Conclusion:Moxibustion with moxa of different storage years(stored for 3 years and 1 year)both can improve the pain,stiffness and motor function in patients with moderate-to-severe KOA.While moxa stored for 3 years has a better therapeutic efficacy in improving stiffness of the knee joint than that stored for 1 year.