Interaction between high-intensity pulsed ion beam (HIPIB) and a double-layer target with titanium film on top of aluminum substrate was simulated. The two-dimensional nonlinear thermal conduction equations, with th...Interaction between high-intensity pulsed ion beam (HIPIB) and a double-layer target with titanium film on top of aluminum substrate was simulated. The two-dimensional nonlinear thermal conduction equations, with the deposited energy in the target taken as source term, were derived and solved by finite differential method. As a result, the two-dimensional spatial and temporal evolution profiles of temperature were obtained for a titanium/aluminum double-layer target irradiated by a pulse of HIPIB. The effects of ion beam current density on the phase state of the target materials near the film and substrate interface were analyzed. Both titanium and aluminum were melted near the interface after a shot when the ion beam current density fell in the range of 100 A/cm2 to 200 A/cm2.展开更多
We used the allele-specific PCR-double digestion method on peripheral myelin protein 22 (PMP22) to determine duplication and deletion mutations in the proband and family members of one family with Charcot-Marie-Toot...We used the allele-specific PCR-double digestion method on peripheral myelin protein 22 (PMP22) to determine duplication and deletion mutations in the proband and family members of one family with Charcot-Marie-Tooth disease type 1 and one family with hereditary neuropathy with liability to pressure palsies. The proband and one subclinical family member from the Charcot-Marie-Tooth disease type 1 family had a PMP22 gene duplication; one patient from the hereditary neuropathy with liability to pressure palsies family had a PMP22 gene deletion. Electron microscopic analysis of ultrathin sections of the superficial peroneal nerve from the two probands demonstrated demyelination and myelin sheath hyperplasia, as well as an 'onion-like' structure in the Charcot-Marie-Tooth disease type 1A patient. We observed an irregular thickened myelin sheath and 'mouse-nibbled'-Iike changes in the patient with hereditary neuropathy with liability to pressure palsies. In the Charcot-Marie-Tooth disease type 1A patient, nerve electrophysiological examination revealed moderate-to-severe reductions in the motor and sensory conduction velocities of the bilateral median nerve, ulnar nerve, tibial nerve, and sural nerve. Moreover, the compound muscle action potential amplitude was decreased. In the patient with hereditary neuropathy with liability to pressure palsies, the nerve conduction velocity of the bilateral tibial nerve and sural nerve was moderately reduced, and the nerve conduction velocity of the median nerve and ulnar nerve of both upper extremities was slightly reduced.展开更多
In this paper, a new pressure reducing valve (PRV) with an orifice plate is proposed. The main objective is to explain the mechanisms of pressure reduction and energy conversion in the new PRV. A numerical simulatio...In this paper, a new pressure reducing valve (PRV) with an orifice plate is proposed. The main objective is to explain the mechanisms of pressure reduction and energy conversion in the new PRV. A numerical simulation method was used to investigate the PRV internal flow field and to analyze the throttling effects of the orifice plate and the transform of thermal parameters as outlet pressure, outlet temperature, velocity, and superheat. A structure improvement method for the valve body and orifice plate is put forward to reduce energy loss. The governing equations for internal flow numerical simulation are composed of the continuity, momentum, energy and k-e transport equations, based on isotropic eddy viscosity theory. Different valve plug displacement models were built to describe the double throttling process. Our analysis shows that the steam pressure drops twice and the degree of superheat increases. There are also lots of eddies which clog the flow channel and disturb the steam flow in the valve cavity after the valve plug and the outlet cavity. After modifying the structure, the numerical results show a better performance of steam flow.展开更多
Mathematical models of three-dimensional temperature fields in underwater welding with moving heat sources are built. Double ellipsoid Gauss model is proposed as heat sources models. Several factors which affect the t...Mathematical models of three-dimensional temperature fields in underwater welding with moving heat sources are built. Double ellipsoid Gauss model is proposed as heat sources models. Several factors which affect the temperature fields of underwater welding are analyzed. Water has little influence on thermal efftciency. Water convection coefftcient varies with the temperature difference between the water and the workpiece , and water convection makes molten pool freeze quickly. With the increase of water depth, the dimensions of heat sources model should be reduced as arc shrinks. Finite element technology is used to solve mathematical models. ANSYS software is used as finite element tool, and ANSYS Parametric Design Language is used to develop subprograms for loading the moving heat sources and the various convection coefftcients. Experiment results show that computational results by using double ellipsoid Gauss heat sources model accord well with the experimental results.展开更多
In this study,natural convection flow in a porous cavity with sinusoidal temperature distribution has been analyzed by a new double multi relaxation time(MRT)Lattice Boltzmann method(LBM).We consider a copper/water na...In this study,natural convection flow in a porous cavity with sinusoidal temperature distribution has been analyzed by a new double multi relaxation time(MRT)Lattice Boltzmann method(LBM).We consider a copper/water nanofluid filling a porous cavity.For simulating the temperature and flow fields,D2Q5 and D2Q9 lattices are utilized respectively,and the effects of different Darcy numbers(Da)(0.001-0.1)and various Rayleigh numbers(Ra)(10^(3)-10^(5))for porosity(ε)between 0.4 and 0.9 have been considered.Phase deviation(θ)changed from 0 toπand the volume fraction of nanoparticles(∅)varied from 0 to 6%.The present results show a good agreement with the previous works,thus confirming the reliability the new numerical method proposed in this paper.It is indicated that the heat transfer rate increases at increasing Darcy number,porosity,Rayleigh number,the volume fraction of nanoparticles and phase deviation.However,the most sensitive parameter is the Rayleigh number.The maximum Nusselt deviation is 10%,32%and 33%for Ra=10^(3),10^(4) and 10^(5),respectively,withε=0.4 toε=0.9.It can be concluded that the effect of Darcy number on the heat transfer rate increases at increasing Rayleigh number,yielding a maximum enhancement of the average Nusselt number around 12%and 61%for Ra=10^(3) and Ra=10^(5),respectively.展开更多
Reservoir boundary shape has a great influence on the transient pressure response of oil wells located in arbitrarily shaped reservoirs. Conventional analytical methods can only be used to calculate transient pressure...Reservoir boundary shape has a great influence on the transient pressure response of oil wells located in arbitrarily shaped reservoirs. Conventional analytical methods can only be used to calculate transient pressure response in regularly shaped reservoirs. Under the assumption that permeability varies exponentially with pressure drop, a mathematical model for well test interpretation of arbitrarily shaped deformable reservoirs was established. By using the regular perturbation method and the boundary element method, the model could be solved. The pressure behavior of wells with wellbore storage and skin effects was obtained by using the Duhamel principle. The type curves were plotted and analyzed by considering the effects of permeability modulus, arbitrary shape and impermeable region.展开更多
溶融动态核极化(dDNP)是一种将分子样品在超低温、强磁场以及微波照射下高度极化,然后经高温高压溶剂快速溶解后立即转移至NMR/MRI系统进行检测的灵敏度增强技术.溶融系统是实现这一过程的关键部分,其性能直接影响样品的溶融、转移效率...溶融动态核极化(dDNP)是一种将分子样品在超低温、强磁场以及微波照射下高度极化,然后经高温高压溶剂快速溶解后立即转移至NMR/MRI系统进行检测的灵敏度增强技术.溶融系统是实现这一过程的关键部分,其性能直接影响样品的溶融、转移效率以及样品极化度的保留程度.本文提出了基于双闭环PID控制算法的自动化溶融系统的控制方案,可在9 min以后达到目标压强1.7 MPa左右并使内部压强被动控制在1.5%以内.将研制的自动化溶融系统集成于自主开发的5 T dDNP仪器系统,可将−271℃的低温样品快速溶融,并于4 s内将其转移到距离11.2 m处的7 T NMR系统进行检测,获得了[1-^(13)C]-丙酮酸钠在溶融态下^(13)C NMR信号9050倍的增强.自动化溶融系统简化了操作步骤,提高了实验的安全性和一致性.展开更多
基金supported by National Natural Science Foundation of China (No.10975026)
文摘Interaction between high-intensity pulsed ion beam (HIPIB) and a double-layer target with titanium film on top of aluminum substrate was simulated. The two-dimensional nonlinear thermal conduction equations, with the deposited energy in the target taken as source term, were derived and solved by finite differential method. As a result, the two-dimensional spatial and temporal evolution profiles of temperature were obtained for a titanium/aluminum double-layer target irradiated by a pulse of HIPIB. The effects of ion beam current density on the phase state of the target materials near the film and substrate interface were analyzed. Both titanium and aluminum were melted near the interface after a shot when the ion beam current density fell in the range of 100 A/cm2 to 200 A/cm2.
基金funded by the National Natural Science Foundation of China, grant No. 81071001 and 30600200
文摘We used the allele-specific PCR-double digestion method on peripheral myelin protein 22 (PMP22) to determine duplication and deletion mutations in the proband and family members of one family with Charcot-Marie-Tooth disease type 1 and one family with hereditary neuropathy with liability to pressure palsies. The proband and one subclinical family member from the Charcot-Marie-Tooth disease type 1 family had a PMP22 gene duplication; one patient from the hereditary neuropathy with liability to pressure palsies family had a PMP22 gene deletion. Electron microscopic analysis of ultrathin sections of the superficial peroneal nerve from the two probands demonstrated demyelination and myelin sheath hyperplasia, as well as an 'onion-like' structure in the Charcot-Marie-Tooth disease type 1A patient. We observed an irregular thickened myelin sheath and 'mouse-nibbled'-Iike changes in the patient with hereditary neuropathy with liability to pressure palsies. In the Charcot-Marie-Tooth disease type 1A patient, nerve electrophysiological examination revealed moderate-to-severe reductions in the motor and sensory conduction velocities of the bilateral median nerve, ulnar nerve, tibial nerve, and sural nerve. Moreover, the compound muscle action potential amplitude was decreased. In the patient with hereditary neuropathy with liability to pressure palsies, the nerve conduction velocity of the bilateral tibial nerve and sural nerve was moderately reduced, and the nerve conduction velocity of the median nerve and ulnar nerve of both upper extremities was slightly reduced.
基金Project (No. 2012C11018-1) supported by the Science and Technology Department of Zhejiang Province,China
文摘In this paper, a new pressure reducing valve (PRV) with an orifice plate is proposed. The main objective is to explain the mechanisms of pressure reduction and energy conversion in the new PRV. A numerical simulation method was used to investigate the PRV internal flow field and to analyze the throttling effects of the orifice plate and the transform of thermal parameters as outlet pressure, outlet temperature, velocity, and superheat. A structure improvement method for the valve body and orifice plate is put forward to reduce energy loss. The governing equations for internal flow numerical simulation are composed of the continuity, momentum, energy and k-e transport equations, based on isotropic eddy viscosity theory. Different valve plug displacement models were built to describe the double throttling process. Our analysis shows that the steam pressure drops twice and the degree of superheat increases. There are also lots of eddies which clog the flow channel and disturb the steam flow in the valve cavity after the valve plug and the outlet cavity. After modifying the structure, the numerical results show a better performance of steam flow.
文摘Mathematical models of three-dimensional temperature fields in underwater welding with moving heat sources are built. Double ellipsoid Gauss model is proposed as heat sources models. Several factors which affect the temperature fields of underwater welding are analyzed. Water has little influence on thermal efftciency. Water convection coefftcient varies with the temperature difference between the water and the workpiece , and water convection makes molten pool freeze quickly. With the increase of water depth, the dimensions of heat sources model should be reduced as arc shrinks. Finite element technology is used to solve mathematical models. ANSYS software is used as finite element tool, and ANSYS Parametric Design Language is used to develop subprograms for loading the moving heat sources and the various convection coefftcients. Experiment results show that computational results by using double ellipsoid Gauss heat sources model accord well with the experimental results.
文摘In this study,natural convection flow in a porous cavity with sinusoidal temperature distribution has been analyzed by a new double multi relaxation time(MRT)Lattice Boltzmann method(LBM).We consider a copper/water nanofluid filling a porous cavity.For simulating the temperature and flow fields,D2Q5 and D2Q9 lattices are utilized respectively,and the effects of different Darcy numbers(Da)(0.001-0.1)and various Rayleigh numbers(Ra)(10^(3)-10^(5))for porosity(ε)between 0.4 and 0.9 have been considered.Phase deviation(θ)changed from 0 toπand the volume fraction of nanoparticles(∅)varied from 0 to 6%.The present results show a good agreement with the previous works,thus confirming the reliability the new numerical method proposed in this paper.It is indicated that the heat transfer rate increases at increasing Darcy number,porosity,Rayleigh number,the volume fraction of nanoparticles and phase deviation.However,the most sensitive parameter is the Rayleigh number.The maximum Nusselt deviation is 10%,32%and 33%for Ra=10^(3),10^(4) and 10^(5),respectively,withε=0.4 toε=0.9.It can be concluded that the effect of Darcy number on the heat transfer rate increases at increasing Rayleigh number,yielding a maximum enhancement of the average Nusselt number around 12%and 61%for Ra=10^(3) and Ra=10^(5),respectively.
文摘Reservoir boundary shape has a great influence on the transient pressure response of oil wells located in arbitrarily shaped reservoirs. Conventional analytical methods can only be used to calculate transient pressure response in regularly shaped reservoirs. Under the assumption that permeability varies exponentially with pressure drop, a mathematical model for well test interpretation of arbitrarily shaped deformable reservoirs was established. By using the regular perturbation method and the boundary element method, the model could be solved. The pressure behavior of wells with wellbore storage and skin effects was obtained by using the Duhamel principle. The type curves were plotted and analyzed by considering the effects of permeability modulus, arbitrary shape and impermeable region.
文摘溶融动态核极化(dDNP)是一种将分子样品在超低温、强磁场以及微波照射下高度极化,然后经高温高压溶剂快速溶解后立即转移至NMR/MRI系统进行检测的灵敏度增强技术.溶融系统是实现这一过程的关键部分,其性能直接影响样品的溶融、转移效率以及样品极化度的保留程度.本文提出了基于双闭环PID控制算法的自动化溶融系统的控制方案,可在9 min以后达到目标压强1.7 MPa左右并使内部压强被动控制在1.5%以内.将研制的自动化溶融系统集成于自主开发的5 T dDNP仪器系统,可将−271℃的低温样品快速溶融,并于4 s内将其转移到距离11.2 m处的7 T NMR系统进行检测,获得了[1-^(13)C]-丙酮酸钠在溶融态下^(13)C NMR信号9050倍的增强.自动化溶融系统简化了操作步骤,提高了实验的安全性和一致性.