The\dDDe)Rhly --CU)Zjw(CO)3(jab--Cr,ilo,W)heterobinuclear m,t'1carbonyl c ompQunds were synthesized and characterized by ic and h Iljlh'Their catalytic activit ies for CO hydrogecation were determined.
Two binuclear copper(I) complexes with novel structures and novel bonding,Cu_2(Ph_2PCH_2PPh_2)Cl_2 (Ph_2PCH_2PPh_2=dppm) and Cu_2(Ph_2P-CH_2CH_2PPh_2)Cl_2 (Ph_2PCH_2CH_2PPh_2=dppe), were prepared and characterized thr...Two binuclear copper(I) complexes with novel structures and novel bonding,Cu_2(Ph_2PCH_2PPh_2)Cl_2 (Ph_2PCH_2PPh_2=dppm) and Cu_2(Ph_2P-CH_2CH_2PPh_2)Cl_2 (Ph_2PCH_2CH_2PPh_2=dppe), were prepared and characterized through elemental analyses, ICP, IR(4000-200 cm^(-1), CsI disc.), ^(31)P-NMR spectra. Their electronic conductivities, oxidation and reduction potentials were measured. Preliminary studies show that both of the two complexes have chlorobridging and phosphorus-bridging structures.展开更多
A novel efficient catalyst for the hydrogenation of carbon dioxide to formic acid ruthenium bisphosphine on functionalized silica was in situ synthesized, affording turnover frequency （TOF） of 1190 h^-1 at 100% sele...A novel efficient catalyst for the hydrogenation of carbon dioxide to formic acid ruthenium bisphosphine on functionalized silica was in situ synthesized, affording turnover frequency （TOF） of 1190 h^-1 at 100% selectivity under 80℃ with total pressure of 16.0 MPa. The catalyst can be separated from the reaction mixture easily and reused with moderate loss of activity.展开更多
Complexes Cl-RuⅡ（dppe）2（Fe Cl4）·2CH2Cl2（2） and Br-RuII（dppe）2（Fe Br4）·2CH2Cl2（3） were prepared by the reaction of trans-RuII（dppe）2Cl2（1） with FeX 3（X = Cl, Br）. More interestingly, the ce...Complexes Cl-RuⅡ（dppe）2（Fe Cl4）·2CH2Cl2（2） and Br-RuII（dppe）2（Fe Br4）·2CH2Cl2（3） were prepared by the reaction of trans-RuII（dppe）2Cl2（1） with FeX 3（X = Cl, Br）. More interestingly, the central Ru atoms of RuII（dppe）-based complexes（2 and 3） define a tetragonal pyramid with five-coordination. The temperature dependence magnetic susceptibilities indicate that the xMT values of complexes 2 and 3 are almost constant at 50~300 K, and the xMT values sharply decrease with further decreasing the temperature at low temperature due to the zero-field splitting（ZFS） of high spin Fe（III） ions.展开更多
Avidin-liposome complex is a specific chiral selector used to separate the enantiomers of D,L-tryptophan,D,L-phenylthiohydantoin -serine（D,L-PTH-Ser）,D,L-phenylthiohydantoin-threonine（D,L-PTH-Thr） and R,S-pioglita...Avidin-liposome complex is a specific chiral selector used to separate the enantiomers of D,L-tryptophan,D,L-phenylthiohydantoin -serine（D,L-PTH-Ser）,D,L-phenylthiohydantoin-threonine（D,L-PTH-Thr） and R,S-pioglitazone hydrochloride in capillary electrochromatography（CEC）.The avidin is immobilized on the phospholipids coated in the capillary.The liposome used for the phospholipid coating contains l,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-（Cap biotinyl）（sodium salt） （Biotinyl-cap-DPPE）（16：0） and different proportions of L-α-phosphatidylserine（PS） in Tris（hydroxymethyl） aminomethane （Tris） buffer at pH 7.4.A good resolution and reproducibility was obtained by coating the capillary with Biotinyl-cap-DPPE/PS （80：20,mol%） followed by immobilization of 1 mg/mL of avidin solution in N-（2-hydroxyethyl） piperazine-N＇-（2-ethanesulfonic acid） （HEPES） buffer at pH 7.4.A comparative study of chiral separation efficiency with different capillary coating methods and preconditioning conditions was conducted.Finally,the electrochromatographic method was successfully used to separate enantiomers of pioglitazone hydrochloride.Therefore,coated CEC will be a promising tool for pharmaceutical enantiomers separation in new drug development.展开更多
文摘The\dDDe)Rhly --CU)Zjw(CO)3(jab--Cr,ilo,W)heterobinuclear m,t'1carbonyl c ompQunds were synthesized and characterized by ic and h Iljlh'Their catalytic activit ies for CO hydrogecation were determined.
文摘Two binuclear copper(I) complexes with novel structures and novel bonding,Cu_2(Ph_2PCH_2PPh_2)Cl_2 (Ph_2PCH_2PPh_2=dppm) and Cu_2(Ph_2P-CH_2CH_2PPh_2)Cl_2 (Ph_2PCH_2CH_2PPh_2=dppe), were prepared and characterized through elemental analyses, ICP, IR(4000-200 cm^(-1), CsI disc.), ^(31)P-NMR spectra. Their electronic conductivities, oxidation and reduction potentials were measured. Preliminary studies show that both of the two complexes have chlorobridging and phosphorus-bridging structures.
基金the National Natural Science Foundation of China （No.20173048） the Specialized Research Fund for the Doctoral Program of Higher Education （No. 20030335068）+1 种基金 the Scientific Research Fund of Zhcjiang Provincial Education Department （No. 20040320） Zhcjiang Provincial Natural Science Foundation of China （No. Y405088）.
文摘A novel efficient catalyst for the hydrogenation of carbon dioxide to formic acid ruthenium bisphosphine on functionalized silica was in situ synthesized, affording turnover frequency （TOF） of 1190 h^-1 at 100% selectivity under 80℃ with total pressure of 16.0 MPa. The catalyst can be separated from the reaction mixture easily and reused with moderate loss of activity.
文摘Complexes Cl-RuⅡ（dppe）2（Fe Cl4）·2CH2Cl2（2） and Br-RuII（dppe）2（Fe Br4）·2CH2Cl2（3） were prepared by the reaction of trans-RuII（dppe）2Cl2（1） with FeX 3（X = Cl, Br）. More interestingly, the central Ru atoms of RuII（dppe）-based complexes（2 and 3） define a tetragonal pyramid with five-coordination. The temperature dependence magnetic susceptibilities indicate that the xMT values of complexes 2 and 3 are almost constant at 50~300 K, and the xMT values sharply decrease with further decreasing the temperature at low temperature due to the zero-field splitting（ZFS） of high spin Fe（III） ions.
文摘Avidin-liposome complex is a specific chiral selector used to separate the enantiomers of D,L-tryptophan,D,L-phenylthiohydantoin -serine（D,L-PTH-Ser）,D,L-phenylthiohydantoin-threonine（D,L-PTH-Thr） and R,S-pioglitazone hydrochloride in capillary electrochromatography（CEC）.The avidin is immobilized on the phospholipids coated in the capillary.The liposome used for the phospholipid coating contains l,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-（Cap biotinyl）（sodium salt） （Biotinyl-cap-DPPE）（16：0） and different proportions of L-α-phosphatidylserine（PS） in Tris（hydroxymethyl） aminomethane （Tris） buffer at pH 7.4.A good resolution and reproducibility was obtained by coating the capillary with Biotinyl-cap-DPPE/PS （80：20,mol%） followed by immobilization of 1 mg/mL of avidin solution in N-（2-hydroxyethyl） piperazine-N＇-（2-ethanesulfonic acid） （HEPES） buffer at pH 7.4.A comparative study of chiral separation efficiency with different capillary coating methods and preconditioning conditions was conducted.Finally,the electrochromatographic method was successfully used to separate enantiomers of pioglitazone hydrochloride.Therefore,coated CEC will be a promising tool for pharmaceutical enantiomers separation in new drug development.
