Currently, the population percentage of diabetics suffering Diabetic Peripheral Neuropathy (DPN) and foot-drop gait anomaly was estimates as 15% in the United States. The onset of foot-drop could not be detected until...Currently, the population percentage of diabetics suffering Diabetic Peripheral Neuropathy (DPN) and foot-drop gait anomaly was estimates as 15% in the United States. The onset of foot-drop could not be detected until symptoms could be observed visually, patient falling or patient experiencing painful gait issues and expensive medical tests. This research showed that by utilizing the plantar-pressure characteristics of DPN drop-foot gait, a set of index could be developed for the severity of DPN.展开更多
An effective and fast method for assay of micro-amounts of glucose was set up. A new technique for preparation of enzyme columns based on enzyme immobilization by sol-gel was investigated. Glucose oxidase(GOD) and hor...An effective and fast method for assay of micro-amounts of glucose was set up. A new technique for preparation of enzyme columns based on enzyme immobilization by sol-gel was investigated. Glucose oxidase(GOD) and horseradish peroxidase(HRP) mixed with SiO 2 nanoparticles and polyvinyl butyral(PVB) medium were immobilized on the surface of capillary tube, respectively. The experimental results show that nanoparticles can significantly enhance the catalytic activity of immobilized enzyme. Based on GOD column and HRP column, a liquid droplet sensor was developed for the determination of glucose solution. The effect of separated columns and mixed columns on the response of glucose sensor was investigated. The sensor showed a linear response in a range of 2-400 ng/mL with a detection limit of 0.3 ng/mL under the optimum conditions. The characteristics of the sensor including effect of flow-rate, pH and temperature were discussed.展开更多
文摘Currently, the population percentage of diabetics suffering Diabetic Peripheral Neuropathy (DPN) and foot-drop gait anomaly was estimates as 15% in the United States. The onset of foot-drop could not be detected until symptoms could be observed visually, patient falling or patient experiencing painful gait issues and expensive medical tests. This research showed that by utilizing the plantar-pressure characteristics of DPN drop-foot gait, a set of index could be developed for the severity of DPN.
文摘An effective and fast method for assay of micro-amounts of glucose was set up. A new technique for preparation of enzyme columns based on enzyme immobilization by sol-gel was investigated. Glucose oxidase(GOD) and horseradish peroxidase(HRP) mixed with SiO 2 nanoparticles and polyvinyl butyral(PVB) medium were immobilized on the surface of capillary tube, respectively. The experimental results show that nanoparticles can significantly enhance the catalytic activity of immobilized enzyme. Based on GOD column and HRP column, a liquid droplet sensor was developed for the determination of glucose solution. The effect of separated columns and mixed columns on the response of glucose sensor was investigated. The sensor showed a linear response in a range of 2-400 ng/mL with a detection limit of 0.3 ng/mL under the optimum conditions. The characteristics of the sensor including effect of flow-rate, pH and temperature were discussed.
基金科技部"中国新加坡联合研究计划 (0 0 3/ 1 0 1 / 0 4 ) (NSTB- MOST Joint Research Program)"资助项目 (NSTB:National Science and Technology Bureau of SingaporeMOST:Ministry of Science and Technology of China.)
文摘详细介绍了光纤、电容液滴分析仪 (FCDA:Fiber- Capacitive Drop Analyzer)的系统设计方案和各组成部分的具体实现方法 ,包括液滴传感器的设计、微量供液系统的设计。
