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A data-driven model of drop size prediction based on artificial neural networks using small-scale data sets 被引量:1
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作者 Bo Wang Han Zhou +3 位作者 Shan Jing Qiang Zheng Wenjie Lan Shaowei Li 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2024年第2期71-83,共13页
An artificial neural network(ANN)method is introduced to predict drop size in two kinds of pulsed columns with small-scale data sets.After training,the deviation between calculate and experimental results are 3.8%and ... An artificial neural network(ANN)method is introduced to predict drop size in two kinds of pulsed columns with small-scale data sets.After training,the deviation between calculate and experimental results are 3.8%and 9.3%,respectively.Through ANN model,the influence of interfacial tension and pulsation intensity on the droplet diameter has been developed.Droplet size gradually increases with the increase of interfacial tension,and decreases with the increase of pulse intensity.It can be seen that the accuracy of ANN model in predicting droplet size outside the training set range is reach the same level as the accuracy of correlation obtained based on experiments within this range.For two kinds of columns,the drop size prediction deviations of ANN model are 9.6%and 18.5%and the deviations in correlations are 11%and 15%. 展开更多
关键词 Artificial neural network drop size Solvent extraction Pulsed column Two-phase flow HYDRODYNAMICS
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Influence of Wellbore Trajectory on Pressure Drop and Fluid Discharge
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作者 Ruidong Wu Guowei Wang +2 位作者 Zhixing Yang Ruiquan Liao Yang Cheng 《Fluid Dynamics & Materials Processing》 EI 2023年第8期2053-2066,共14页
An experimental analysis has been conducted to study the process of fluid accumulation for different borehole trajectories.More specifically,five heel angles have been experimentally realized to simulate the borehole ... An experimental analysis has been conducted to study the process of fluid accumulation for different borehole trajectories.More specifically,five heel angles have been experimentally realized to simulate the borehole trajectory of the sloping section of the formation.The fluid-carrying capacity,pressure drop and fluid discharge volatility have been investigated for these conditions and,accordingly,the relationship between heel angle and wellbore pressure drop fluid-carrying capacity has been determined.The results show that while the reasonable roll angle can increase the pressure loss in the wellbore,it is beneficial to drainage.In terms of pressure loss and liquid-carrying capacity,when the heeling angle is 50°,the latter is increased while the former becomes very high,which indicates that when drilling and completing wells on site,a 50°roll angle should be avoided.It is found that the main reason for the increase of the total pressure drop in the wellbore is the increase of the local pressure loss in the inclined section.From the perspective of drainage stability,when there is heeling in the inclined section of the horizontal well,the fluctuation of the wellbore drainage tends to be enhanced.Through the comparison of the Beggs-Brill(B-B)and Mukherjee-Brill liquid holdup methods,it is found that B-B method better predicts liquid holdup.A new method for calculating the pressure drop in the inclined section in the presence of lateral inclination is obtained by taking into account the pressure drop in the curved section.Through comparison with experimental data,it is found that the error is within 20%,and the prediction accuracy is high. 展开更多
关键词 Horizontal well slant section heel angle pressure drop drainage quantity
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Buckling Properties of Water-Drop-Shaped Pressure Hulls with Various Shape Indices Under Hydrostatic External Pressure
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作者 DING Xiao-de ZHANG Jian +2 位作者 WANG Fang JIAO Hui-feng WANG Ming-lu 《China Ocean Engineering》 SCIE EI CSCD 2024年第1期1-17,共17页
The water-drop-shaped pressure hull has a good streamline,which has good application prospect in the underwater observatory.Therefore,this study conducted analytical,experimental and numerical investigation of the buc... The water-drop-shaped pressure hull has a good streamline,which has good application prospect in the underwater observatory.Therefore,this study conducted analytical,experimental and numerical investigation of the buckling properties of water-drop-shaped pressure hulls under hydrostatic pressure.A water-drop experiment was conducted to design water-drop-shaped pressure hulls with various shape indices.The critical loads for the water-drop-shaped pressure hulls were resolved by using Mushtari’s formula.Several numerical simulations including linear buckling analysis and nonlinear buckling analysis including eigenmode imperfections were performed.The results indicated that the critical loads resolved by Mushtari's formula were in good agreement with the linear buckling loads from the numerical simulations.This formula can be extended to estimate the buckling capacity of water-drop-shaped pressure hulls.In addition,three groups of pressure hulls were fabricated by using stereolithography,a rapid prototyping technique.Subsequently,three groups of the pressure hulls were subjected to ultrasonic measurements,optical scanning,hydrostatic testing and numerical analysis.The experimental results were consistent with the numerical results.The results indicate that the sharp end of the water-drop-shaped pressure hulls exhibited instability compared with the blunt end.This paper provides a new solution to the limitations of experimental studies on the water-drop-shaped pressure hulls as well as a new configuration and evaluation method for underwater observatories. 展开更多
关键词 BUCKLING pressure hull water drop underwater observatory
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Evaluation of frictional pressure drop correlations for air-water and air-oil two-phase flow in pipeline-riser system
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作者 Nai-Liang Li Bin Chen 《Petroleum Science》 SCIE EI CAS CSCD 2024年第2期1305-1319,共15页
Accurate prediction of the frictional pressure drop is important for the design and operation of subsea oil and gas transporting system considering the length of the pipeline. The applicability of the correlations to ... Accurate prediction of the frictional pressure drop is important for the design and operation of subsea oil and gas transporting system considering the length of the pipeline. The applicability of the correlations to pipeline-riser flow needs evaluation since the flow condition in pipeline-riser is quite different from the original data where they were derived from. In the present study, a comprehensive evaluation of 24prevailing correlation in predicting frictional pressure drop is carried out based on experimentally measured data of air-water and air-oil two-phase flows in pipeline-riser. Experiments are performed in a system having different configuration of pipeline-riser with the inclination of the downcomer varied from-2°to-5°to investigated the effect of the elbow on the frictional pressure drop in the riser. The inlet gas velocity ranges from 0.03 to 6.2 m/s, and liquid velocity varies from 0.02 to 1.3 m/s. A total of885 experimental data points including 782 on air-water flows and 103 on air-oil flows are obtained and used to access the prediction ability of the correlations. Comparison of the predicted results with the measured data indicate that a majority of the investigated correlations under-predict the pressure drop on severe slugging. The result of this study highlights the requirement of new method considering the effect of pipe layout on the frictional pressure drop. 展开更多
关键词 Frictional pressure drop Pipeline-riser Gas-liquid two-phase flow Severe slugging CORRELATION
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A combined computational/experimental study of anode-concerned voltage drop in aqueous primary Mg-air batteries
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作者 Wen Xu Min Deng +5 位作者 Darya Snihirova Linqian Wang Yulong Wu Sviatlana V.Lamaka Mikhail L.Zheludkevich Daniel Hoche 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2024年第5期1854-1866,共13页
The voltage drop appearing at Mg anode-electrolyte interface is a critical issue for the battery power and energy density of aqueous primary Mg-air batteries.The respective voltage loss is typically assigned to the de... The voltage drop appearing at Mg anode-electrolyte interface is a critical issue for the battery power and energy density of aqueous primary Mg-air batteries.The respective voltage loss is typically assigned to the deposits layer forming on the anode surface during discharge.In this work,we experimentally and computationally investigate the critical factors affecting the voltage drop at Mg anode towards a deeper understanding of the contribution of deposit and its growth.A two-dimensional(2D)mathematical model is proposed to compute the voltage drop of Mg-0.15Ca wt.%alloy(Mg-0.15Ca)by means of a semi-empirical formulas and experiments-based modification model,considering the effect of discharge current density,the negative difference effect(NDE)and surface deposits layer itself.This model is utilized to simulate the discharge potential of the anode at predefined experimental current densities.The computed voltage drop(half-cell voltage)is in good agreement with the experimental value.The applicability of the mathematical model is successfully validated on the second material(namely high-purity Mg). 展开更多
关键词 Aqueous Mg-air battery Voltage drop NDE Charge transfer Deposits-related resistances
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Effect of perforation density distribution on production of perforated horizontal wellbore
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作者 KAREEM Hasanain J. HASINI Hasril ABDULWAHID Mohammed A. 《Petroleum Exploration and Development》 SCIE 2024年第2期464-475,共12页
To address the issue of horizontal well production affected by the distribution of perforation density in the wellbore,a numerical model for simulating two-phase flow in a horizontal well is established under two perf... To address the issue of horizontal well production affected by the distribution of perforation density in the wellbore,a numerical model for simulating two-phase flow in a horizontal well is established under two perforation density distribution conditions(i.e.increasing the perforation density at inlet and outlet sections respectively).The simulation results are compared with experimental results to verify the reliability of the numerical simulation method.The behaviors of the total pressure drop,superficial velocity of air-water two-phase flow,void fraction,liquid film thickness,air production and liquid production that occur with various flow patterns are investigated under two perforation density distribution conditions based on the numerical model.The total pressure drop,superficial velocity of the mixture and void fraction increase with the air flow rate when the water flow rate is constant.The liquid film thickness decreases when the air flow rate increases.The liquid and air productions increase when the perforation density increases at the inlet section compared with increasing the perforation density at the outlet section of the perforated horizontal wellbore.It is noted that the air production increases with the air flow rate.Liquid production increases with the bubble flow and begins to decrease at the transition point of the slug-stratified flow,then increases through the stratified wave flow.The normalized liquid flux is higher when the perforation density increases at the inlet section,and increases with the radial air flow rate. 展开更多
关键词 horizontal wellbore two-phase flow pattern perforation density wellbore pressure drop void fraction production performance
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Ladder Time Stepwise Inertia Coordinated Control Method of Multiple Wind Farms to Suppress System Frequency Secondary Drop
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作者 He Li Xianchao Liu +1 位作者 Jidong Li Yuchen Qiu 《Energy Engineering》 EI 2024年第8期2293-2311,共19页
Currently,both regulated and deregulated power trading exist in China’s power system,which has caused imbalanced funds in the electricity market.In this paper,a simulation analysis of the electricity market with wind... Currently,both regulated and deregulated power trading exist in China’s power system,which has caused imbalanced funds in the electricity market.In this paper,a simulation analysis of the electricity market with wind energy resources is conducted,and the calculation methods of unbalanced funds are investigated systematically.In detail,the calculation formulas of unbalanced funds are illustrated based on their definition,and a two-track electricity market clearing model is established.Firstly,the concept of the dual-track system is explained,and the specific calculation formulas of various types of unbalanced funds are provided.Next,considering the renewable energy consumption,the market clearing model based on DC power flow is constructed and solved;by combining fitting methods of mid-and long-term curves,the unbalanced funds are calculated based on clearing results and formulas. 展开更多
关键词 Wind power stepwise inertial frequency control secondary drop
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Presentation and management outcome of foot drop with tibialis posterior tendon transfer
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作者 Muhammad Saaiq 《World Journal of Orthopedics》 2024年第11期1047-1055,共9页
BACKGROUND Foot drop causes considerable disability.The ankle-dorsiflexion is either weak or lost completely.Additionally,the ankle eversion and toe extensions are also impaired.This results in a high steppage gait wh... BACKGROUND Foot drop causes considerable disability.The ankle-dorsiflexion is either weak or lost completely.Additionally,the ankle eversion and toe extensions are also impaired.This results in a high steppage gait while walking.Overall,the gait is awkward;there is greater energy consumption;increased proneness to sustain injury of the forefoot;and more frequent falling during walking.AIM To document the clinical and epidemiological profile of foot drop patients in our population and evaluate the outcome of tibialis posterior(TP)tendon transfer for restoring the lost dorsiflexion in foot drop.METHODS The study was carried out at the National Institute of Rehabilitation Medicine in Islamabad over a period of 7 years.It included patients of all sexes and ages who presented with foot drop and had no contraindications for the procedure of TP tendon transfer.Exclusion criteria were patients who had contraindications for the operation.For instance,paralyzed posterior leg compartment muscles,Achilles tendon contracture,stiff ankle or toes,unstable ankle joint,weak gastrocnemius and scarred skin spanning over the route of planned tendon transfer.Also,patients who had the foot drop as a result of disc prolapses or brain diseases were excluded.Convenience sampling technique was used.The circum-tibial route of TP tendon transfer was employed.RESULTS Out of 37 patients,26(70.27%)were males whereas 11(29.72%)were females.The mean age was 22.59±8.19 years.Among the underlying causes of foot drop,road traffic accidents constituted the most common cause,found among 20(54.05%)patients.The share of complications included wound infections in 3(8.10%)patients and hypertrophic scars in 2(5.40%)patients.At 1-year postoperative follow-up visits,the outcome was excellent in 8(21.62%),good in 20(54.05%)and moderate in 9(24.31%).CONCLUSION The majority of cases of foot drop resulted from road traffic accidents that directly involved the common peroneal nerve.TP tendon transfer through the circumtibial route was found to be an easily executed effective operation which restored good dorsiflexion of the ankle among the majority of patients. 展开更多
关键词 Foot drop Common peroneal nerve Peroneal nerve palsy Tibialis posterior transfer Tibialis anterior Tendon transfer
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Efficacy of recombinant human epidermal growth factor plus sodium hyaluronate eye drops in diabetic dry eye post-cataract surgery
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作者 Jun-Ling Li Jin Zhao +2 位作者 Zhen-Feng Guo Chang Xiao Xuan Liu 《World Journal of Diabetes》 SCIE 2024年第6期1234-1241,共8页
BACKGROUND Dry eye syndrome(DES)after diabetic cataract surgery can seriously affect the patient’s quality of life.Therefore,effective alleviation of symptoms in patients with this disease has important clinical sign... BACKGROUND Dry eye syndrome(DES)after diabetic cataract surgery can seriously affect the patient’s quality of life.Therefore,effective alleviation of symptoms in patients with this disease has important clinical significance.AIM To explore the clinical effect of recombinant human epidermal growth factor(rhEGF)plus sodium hyaluronate(SH)eye drops on DES after cataract surgery in patients with diabetes.METHODS We retrospectively evaluated 82 patients with diabetes who experienced DES after cataract surgery at Tianjin Beichen Hospital,Affiliated Hospital of Nankai University between April 2021 and April 2023.They were classified into an observation group(42 cases,rhEGF+SH eye drops)and a control group(40 cases,SH eye drops alone),depending on the different treatment schemes.The therapeutic efficacy,dry eye symptom score,tear film breakup time(TFBUT),basic tear secretion score[assessed using Schirmer I test(SIt)],corneal fluorescein staining(FL)score,tear inflammatory markers,adverse reactions during treat-ment,and treatment satisfaction were compared between the two groups.RESULTS Therapeutic efficacy was higher in the observation group compared with the control group.Both groups showed improved TFBUT and dry eye,as well as improved SIt and FL scores after treatment,with a more pronounced improvement in the observation group.Although no marked differences in adverse reactions were observed between the two groups,treatment satisfaction was higher in the observation group.CONCLUSION rhEGF+SH eye drops rendered clinical benefits to patients by effectively ameliorating dry eye and visual impairment with favorable efficacy,fewer adverse reactions,and high safety levels.Thus,this treatment should be promoted in clinical practice. 展开更多
关键词 Recombinant human epidermal growth factor Sodium hyaluronate eye drops Diabetic patients Dry eye syndrome after cataract surgery Therapeutic efficacy
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Flow Rate Measurement of Gravity Infusion Set and Functional Evaluation of Drop Counter: A Pilot Study
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作者 Rina Sakai Shuichi Tanaka +3 位作者 Kaya Murakami Tomomi Mizuhashi Kazuhiro Yoshida Masanobu Ujihira 《Journal of Biomedical Science and Engineering》 2024年第7期129-135,共7页
Developing a novel drop counter by introducing the Internet of Things concept has been vigorously conducted in recent years. Understanding the newly introduced drop counter’s flow rate control accuracy and flow rate ... Developing a novel drop counter by introducing the Internet of Things concept has been vigorously conducted in recent years. Understanding the newly introduced drop counter’s flow rate control accuracy and flow rate count feature is essential for improving safety in infusion management. This study aimed to verify if the new drop counters could secure accurate flow rate and drip count by conducting actual flow rate measurements using gravimetry and functional evaluation. A drop counter was attached to each drip chamber of the infusion set, and an IV drip was conducted at the 100 ml/h flow rate. The weight of discharged physiological saline was measured to plot trumpet curves. Next, three different types of drop counters were evaluated to determine if they maintained drip count accuracy according to the changes in their position angles. The flow rate errors in all conditions indicated trumpet-like curves, exhibiting an overall error range within ±10% in all observation windows. Although every drop counter successfully detected and measured dripping, it was challenging in some counters to detect dripping when the drip chamber was tilted. In comparing adult and pediatric IV sets, the adult IV set was found to be less likely to detect dripping in the angled position. No significant differences in results were confirmed between high and low flow rates, suggesting that the drop count function would not be affected by the flow rate in the ranges of typical infusion practices. Doppler sensors have a wide range of measurements and high sensitivity;the dripping was detected successfully even when the drip chamber was tilted, probably due to the advantages of these sensors. In contrast, miscounts occurred in those equipped with infrared sensors, which could not detect light intensity changes in tilted positions. Understanding the tendencies in flow rate errors in infusion can be valuable information for infusion management. 展开更多
关键词 Gravity Infusion Set drop Counter IV Fluids Flow Rate Trumpet Curves
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Prevalence and Factors Associated with Dry Eyes Syndrome in Glaucomatous Patients on Anti-Glaucoma Eye Drops Followed up at the Garoua Regional Hospital-Northern Cameroon
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作者 Josiane Mare Njoya Dodo Balkissou +3 位作者 Bimingo Noelle Bra’ Eyatcha Viola Dohvoma Yannick Bilong Godefroy Koki 《Open Journal of Ophthalmology》 2024年第3期350-360,共11页
Background: Dry eye and glaucoma are two common pathologies in the elderly, and are very often associated. This association suggests a link between them and between their treatments. Our purpose for this study is to d... Background: Dry eye and glaucoma are two common pathologies in the elderly, and are very often associated. This association suggests a link between them and between their treatments. Our purpose for this study is to determine the prevalence of dry eye in our glaucoma patients treated with eye drops and deduce the factors associated with it. Patients and Methods: We conducted a cross-sectional, analytical study from October 2022 to September 2023 in the ophthalmology department of Garoua Regional Hospital in glaucoma patients aged over 15 years able to answer the Ocular Surface Disease Index (OSDI) questionnaires and treated with antiglaucoma eye drops for more than 3 months. These patients underwent a complete ophthalmological examination and a tear film break-up time test. Results: A total of 73 patients (146 eyes) were examined. The average age of the patients was 47.2 ± 16.5 years, with a male predominance of 54.8%. The prevalence of dry eye syndrome in our patients according to the OSDI score was 56.2% (95% CI) (44.8;67.6). The prevalence of dry eye syndrome on clinical examination of the BUT in the right eye was 83.7% (95% CI) (75.1;92.1) and 79.4% (70.2;88.7) in the left eye. The duration of antiglaucoma treatment was the factor associated with dry eye syndrome (p < 0.05) in glaucoma patients in our setting. Conclusion: Dry Eye Syndrome is common in glaucoma patients on drops in our setting. Treatment duration of more than 1 year seems to be associated with dry eyes. 展开更多
关键词 Dry Eyes GLAUCOMA Conservative Eye drops Médications Garoua-Cameroon
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The Effect of Ginkgo Biloba Leaf Dropping Pill Combined with Butylphthalide Capsule on Cognitive Dysfunction in Patients after Acute Ischemic Stroke and Its Impact on Serum Cytokines
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作者 Yaojie Cai Yuping He +1 位作者 Gang Yang Yan Chen 《Journal of Biosciences and Medicines》 2024年第7期252-262,共11页
Objective: To investigate the therapeutic effect of Ginkgo biloba extract dropping pills combined with butylphthalide capsules on cognitive dysfunction in patients after acute ischemic stroke (AIS) and its impact on s... Objective: To investigate the therapeutic effect of Ginkgo biloba extract dropping pills combined with butylphthalide capsules on cognitive dysfunction in patients after acute ischemic stroke (AIS) and its impact on serum cytokines CRP, IL-6, and Hcy. Methods: This study selected 76 patients with cognitive dysfunction after ischemic stroke who were hospitalized at Zhuji People’s Hospital from January 2023 to January 2024. The patients were divided into two groups. The control group was treated with butylphthalide capsules, while the combination group received Ginkgo biloba extract dropping pills in addition to the treatment given to the control group. The neurological function, cognitive function, activities of daily living, and levels of serum cytokines CRP, IL-6, and Hcy were compared between the two groups after 1 month and 3 months of treatment. Results: The NIHSS scores, MMSE scores, ADL scores, and levels of CRP, IL-6, and Hcy in both groups showed statistically significant differences compared to before treatment (P Conclusion: The combination of Ginkgo biloba extract dropping pills and butylphthalide capsules has a better therapeutic effect on cognitive dysfunction in patients after ischemic stroke. It can improve the neurological function and cognitive function of patients, enhance their ability to perform daily activities, and reduce inflammatory responses. 展开更多
关键词 Acute Ischemic Stroke Ginkgo Biloba Leaf drop Pills Butylphthalein Cognitive Impairment
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Temperature Drop of Molten Metals in Open Channels
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作者 Miguel A. Barron-Meza Joan Reyes-Miranda 《World Journal of Engineering and Technology》 2024年第3期493-500,共8页
The temperature drop of molten metal flowing in open channels is numerically determined. Rectangular, trapezoidal and triangular geometries are considered. The overall heat transfer coefficients for the bottom, side w... The temperature drop of molten metal flowing in open channels is numerically determined. Rectangular, trapezoidal and triangular geometries are considered. The overall heat transfer coefficients for the bottom, side walls and free surface of the channel have been taken from the literature. For each geometry, the volumetric flow rate, mean residence time and temperature drop as a function of the channel inclination angle were determined. The rectangular and trapezoidal geometries present the smallest temperature drops, while the triangular geometry presents the greatest temperature drop. The factors that most affect this drop are the value of the free surface area of the channel, and the average residence time of the molten metal in the channel. 展开更多
关键词 Free Surface Heat Transfer Molten Metal Open Channel Geometry Residence Time Temperature drop
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Improvement of Temperature Drop Model Parameters for 4200mm/3500mm Rolling of Baosteel Medium and Thick Plate
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作者 Kong Peng 《Frontiers of Metallurgical Industry》 2024年第1期27-30,共4页
Based on the temperature situation during the rolling process of 4200 mm/3500 mm medium and thick plates at Baosteel,this article analyzes the influencing factors of temperature changes during the rolling process from... Based on the temperature situation during the rolling process of 4200 mm/3500 mm medium and thick plates at Baosteel,this article analyzes the influencing factors of temperature changes during the rolling process from the perspective of heat transfer theory and the temperature change law during the rolling process.The temperature loss during the four rolling processes is tracked on site,and the temperature drop model parameters during the rolling process of 4200mm/3500mm medium and thick plates at Baosteel are quantitatively provided.It is applied to actual rolling production and has achieved good results. 展开更多
关键词 medium thickness plate rolling process temperature drop
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Clinical Observation of Recombinant Bovine Basic Fibroblast Growth Factor Eye Gel Combined with Tobramycin Dexamethasone Eye Drops in the Treatment of Dry Eye Syndrome in Patients after Cataract Surgery
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作者 Zhishun Mao Xiaoxue Mei 《Journal of Clinical and Nursing Research》 2024年第8期296-301,共6页
Objective:To evaluate the therapeutic effect of recombinant bovine basic fibroblast growth factor(rbFGF)eye gel combined with tobramycin-dexamethasone(TOB-Dex)eye drops on dry eye syndrome(DES)after cataract surgery.M... Objective:To evaluate the therapeutic effect of recombinant bovine basic fibroblast growth factor(rbFGF)eye gel combined with tobramycin-dexamethasone(TOB-Dex)eye drops on dry eye syndrome(DES)after cataract surgery.Methods:86 patients with DES after cataract surgery,admitted from November 2021 to November 2023,were randomly divided into groups.The observation group included 43 patients treated with rbFGF eye gel combined with TOB-Dex eye drops.The reference group included 43 patients treated with TOB-Dex eye drops alone.Multiple indicators,including total effective rate and clinical symptom scores,were compared between the two groups.Results:The total effective rate in the observation group was higher than in the reference group(P<0.05).Before treatment,there were no differences in clinical symptom scores,serum factors,or disease severity scores between the two groups(P>0.05).Three weeks after treatment,the observation group had lower clinical symptom scores,serum factors,and disease severity scores compared to the reference group(P<0.05).The adverse reaction rate in the observation group was lower than in the reference group(P<0.05).Conclusion:rbFGF eye gel combined with TOB-Dex eye drops can improve the clinical efficacy for patients with DES after cataract surgery,alleviate disease symptoms,reduce inflammatory responses,and have fewer adverse reactions. 展开更多
关键词 Recombinant bovine basic fibroblast growth factor eye gel Tobramycin-dexamethasone eye drops Cataract surgery Dry eye syndrome
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Effect of dynamic loading conditions on the dynamic performance of MP1 energy-absorbing rockbolts:Insight from laboratory drop test 被引量:3
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作者 Jinfu Lou Fuqiang Gao +2 位作者 Jianzhong Li Guiyang Yuan Mostafa Sharifzadeh 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2023年第2期215-231,共17页
Energy-absorbing rockbolts have been widely adopted in burst-prone excavation support, and their serviceability is closely related to the frequency and magnitude of seismic events. In this research, the splittube drop... Energy-absorbing rockbolts have been widely adopted in burst-prone excavation support, and their serviceability is closely related to the frequency and magnitude of seismic events. In this research, the splittube drop test with varying impact energy was conducted to reproduce the dynamic performance of MP1rockbolts under a wide range of seismic event magnitudes. The test results showed that the impact process could be subdivided into four distinct stages, i.e. mobilization, strain hardening, plastic flow(ductile), and rebound stage, of which strain hardening and plastic flow are the primary energy absorbing stages. As the impact energy per drop increases from 8.1 to 46.7 k J, the strain rate of the shank varies between 1.20 and 2.70 s^(-1), and the average impact load is between 240 and 270kN, which may be considered as constant. The MP1 rockbolt has a cumulative maximum energy absorption(CMEA) of 31.9–40.0 k J/m, with an average of 35.0 k J/m, and the elongation rate is 11.4%–14.7%, with an average of 12.7%, both of which are negatively correlated with the impact energy per drop. Regression analysis shows that energy absorption and shank elongation, as well as momentum input and impact duration,conform to the linear relationship. The complete dynamic capacity envelope of MP1 rockbolts is proposed, which reflects the dynamic bearing capacity, elongation, and distinct stages. This study is helpful to better understand the dynamic characteristics of energy-absorbing rockbolts and assist design engineers in robust reinforcement systems design to mitigate rockburst damage in seismically active underground excavations. 展开更多
关键词 Energy-absorbing rockbolt Dynamic performance drop test Residual elastic energy(REE) Energy absorption rate(EAR) Dynamic capacity envelope
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Effects of endogenous dopamine induced by low concentration atropine eye drops on choroidal neovascularization in high myopia mice 被引量:3
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作者 Yan-Yan Ji Shi-Xi Zhang +1 位作者 Ye Kang Song Chen 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2023年第7期1034-1040,共7页
AIM:To evaluate effects of endogenous dopamine induced by low concentration atropine eye drops on choroidal neovascularization(CNV)in high myopia mice.METHODS:The C57BL/6J mice were deprived of the right eye for 4wk,a... AIM:To evaluate effects of endogenous dopamine induced by low concentration atropine eye drops on choroidal neovascularization(CNV)in high myopia mice.METHODS:The C57BL/6J mice were deprived of the right eye for 4wk,and the high myopia was diagnosed by optometry,the diopter was less than-6.00 D,and CNV was induced by 532 nm laser.The changes of dopamine D1 receptor(DRD1),dopamine D2 receptor(DRD2),and vascular endothelial growth factor A(VEGFA)were detected by Western blot technology at 0.5,1,2h,and 7d after 0.01%,0.05%,and 0.1%atropine eye drops,respectively,the area of CNV was measured.RESULTS:Significant increases were observed on the expression of DRD2 in mouse high myopia model at 0.5,1,2h,7d with 0.05%and 0.1%atropine eye drops(P<0.05).Significant decreases were observed on the expression of DRD1 and VEGFA in mouse high myopia model at 0.5,1,2h,7d with 0.05%and 0.1%atropine eye drops(P<0.05).The area of CNV induced by laser in the drug-treated group was significantly smaller than that in the control group,and the higher the concentration,the more significant the inhibitory effect(P<0.05).CONCLUSION:The 0.01%,0.05%,0.1%atropine eye drops can decrease the level of VEGFA and inhibit high myopia CNV indirectly by up-regulating the level of DRD2 and down-regulating the level of DRD1,and the effect of 0.05%and 0.1%atropine eye drops is more significant. 展开更多
关键词 high myopia choroidal neovascularization low concentration atropine eye drops dopamine D1 receptor dopamine D2 receptor
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The role of cochlear implantation in alleviating Tumarkin drop attacks of Meniere's disease;a case report 被引量:1
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作者 Chiara Filippi Edoardo Covelli +2 位作者 Haitham H.Elfarargy Simonetta Monini Maurizio Barbara 《Journal of Otology》 CAS CSCD 2023年第3期168-172,共5页
Ménière’s disease(MD)patients may suffer episodes of sudden falls,named Tu markin drop attacks(DAs).This fall occurs abruptly and without warning or loss of consciousness.DAs usually aggravate the clinical ... Ménière’s disease(MD)patients may suffer episodes of sudden falls,named Tu markin drop attacks(DAs).This fall occurs abruptly and without warning or loss of consciousness.DAs usually aggravate the clinical picture of MD and are challenging to manage.The present report describes a case treated by cochlear implantation(CI)due to concomitant deafness and offers some clinical considerations for this condition.A male patient aged 48 years with a 10-year history of definite bilateral MD had profound SNHL on the right and severe SNHL on the left side.He suffered from intermittent attacks of vertigo,ear fullness,and tinnitus and,in the last year,had developed DAs and experienced 14 episodes in the previous six months.The preoperative category of acoustic performance was 3.The Dizziness Handicap Inventory(DHI)questionnaire showed a total score of 46,which indicated a moderate degree of disability.A CI was planned for the right side.The patient did not report any further DAs episode for two years since then.The postoperative category of acoustic performance became 11,and the postoperative DHI questionnaire showed a decrease in the total score(from 46 to 19),which indicated a mild disability.Unilateral CI effectively alleviated the DAs associated with bilateral MD.Our report proposes a new modality for managing vertiginous symptoms in cases of MD with hearing loss without the need for more aggressive surgical interventions with the need for clinical trials to confirm our results. 展开更多
关键词 Meniere's disease Tumarkin drop attacks Hearing loss Cochlear implant
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Numerical simulation of drop weight impact sensitivity evaluation criteria for pressed PBXs 被引量:1
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作者 Hong-zheng Duan Yan-qing Wu +1 位作者 Kun Yang Feng-lei Huang 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2023年第1期76-90,共15页
A thorough understanding of drop-weight impacted responses for polymer-bonded explosives(PBXs)is significant to evaluate their impact sensitivity.The characteristics of the drop-weight impacted pressed PBXs including ... A thorough understanding of drop-weight impacted responses for polymer-bonded explosives(PBXs)is significant to evaluate their impact sensitivity.The characteristics of the drop-weight impacted pressed PBXs including deforming,fracturing,forming a local high-temperature region and igniting,were simulated using a coupled mechanical-thermo-chemical model integrating micro-defects evolution.A novel evaluation method for impact sensitivity is established using the relation between the input kinetic energy and the output energy due to deformation,crushing energy,local hot spot energy and ignition.The effects of impact velocity on sensitivity were analyzed and the critical local ignition impact velocity is determined as 4.0-4.5 m/s.The simulated results show that shear-crack friction heating is the dominant ignition mechanism.The region along the boundary of PBXs sample is the most hazardous regions where ignition first occur.The propagation of stress wave in PBXs causes shear-crack hotspot and bulk temperature exhibiting an approximate 45°direction evolution path,which is the main reason that dominated damage-ignition region transits from the boundary to the central of sample. 展开更多
关键词 Polymer-bonded explosives(PBXs) drop weight impact Numerical simulation Sensitivity evaluation criterion Hotspot mechanism
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Pressure drop of structured packing in pilot column and comparison to common correlations
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作者 Emil Madsen Randi Neerup +3 位作者 Arne Gladis Jens K.Jørsboe Nicolas von Solms Philip L.Fosbøl 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2023年第12期281-291,共11页
Packed columns are widely used in the chemical industry such as absorption,stripping,distillation,and extraction in the production of e.g.organic chemicals,and pharmaceuticals.Pressure loss and pressure drop correlati... Packed columns are widely used in the chemical industry such as absorption,stripping,distillation,and extraction in the production of e.g.organic chemicals,and pharmaceuticals.Pressure loss and pressure drop correlations are of special interest when it comes to the hydrodynamic properties of a column.The pressure loss across the column is of interest in the design phase when the size of the blower to drive the gas stream through the column has to be decided.The loading point and flooding point are also influenced by the pressure loss and the area of operation is determined from these points.This work examines four different correlations on pressure drop.The correlations are(i)Ergun’s equation(1952),(ii)an improved version of Ergun’s equation by Stichlmair,Bravo,and Fair(1989),(iii)an equation developed by Billet and Schultes(1999),and(iv)an equation by Rocha,Bravo,and Fair(1993).The complexity of the correlations is increasing in the mentioned order,Ergun’s equation being the simplest one.This study investigates if the more complicated correlations give better predictions to pressure drop in packed columns.This is determined by comparing the correlations to experimental data for pressure drop in a packed column with 8.2 m of structured packing using water as the liquid and atmospheric air as the gas.Seven experiments were carried out for determining the pressure drop in the column with liquid flows varying from 0 to 500 kg·h^(-1).At constant liquid flow,the gas flow was varied from approximately 10 to 70 kg·h^(-1).The pressure drop across the non-wetted column was best described by the correlation by Rocha et al.while the pressure drop for liquid flows from 100 to 500 kg·h^(-1)was,in general,best described by Stichlmair’s equation.For an irrigated column,the highest deviation was a predicted pressure drop 69.6%lower than measured.The best prediction was 0.1%higher than the measured.This study shows,surprisingly,that for a system of water and atmospheric air,complicated correlations on pressure drop determination do not provide better estimates than simple equations. 展开更多
关键词 Pressure drop correlations Packed columns Structured packing Fluid dynamics
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