Mediating role of social support in dysphoria,despondency,and quality of life in patients undergoing maintenance hemodialysis

BACKGROUND Dysphoria and despondency are prevalent psychological issues in patients undergoing Maintenance Hemodialysis(MHD)that significantly affect their quality of life(QOL).High levels of social support can significantly improve the physical and mental well-being of patients undergoing MHD.Currently,there is limited research on how social support mediates the relationship between dysphoria,despondency,and overall QOL in patients undergoing MHD.It is imperative to investigate this mediating effect to mitigate dysphoria and despondency in patients undergoing MHD,ultimately enhancing their overall QOL.AIM To investigate the mediating role of social support in relationships between dysphoria,despondency,and QOL among patients undergoing MHD.METHODS Participants comprised 289 patients undergoing MHD,who were selected using a random sampling approach.The Social Support Rating Scale,Self-Rating Anxiety Scale,Self-Rating Depression Scale,and QOL Scale were administered.Correlation analysis was performed to examine the associations between social support,dysphoria,despondency,and QOL in patients undergoing MHD.To assess the mediating impact of social support on dysphoria,despondency,and QOL in patients undergoing MHD,a bootstrap method was applied.RESULTS Significant correlations among social support,dysphoria,despondency,and quality in patients undergoing MHD were observed(all P<0.01).Dysphoria and despondency negatively correlated with social support and QOL(P<0.01).Dysphoria and despondency had negative predictive impacts on the QOL of patients undergoing MHD(P<0.05).The direct effect of dysphoria on QOL was statistically significant(P<0.05).Social support mediated the relationship between dysphoria and QOL,and this mediating effect was significant(P<0.05).Similarly,the direct effect of despondency on QOL was significant(P<0.05).Moreover,social support played a mediating role between despondency and QOL,with a significant mediating effect(P<0.05).CONCLUSION These findings suggest that social support plays a significant mediating role in the relationship between dysphoria,despondency,and QOL in patients undergoing MHD.

Health-related quality of life among congestive heart failure patients with preserved and reduced ejection fraction

Objective:To determine factors that affect the health-related quality of life(HRQOL)of congestive heart failure(CHF)patients with preserved and reduced ejection fraction.Methods:A cross-sectional study design was used for this study.The stratified random sampling was applied for each subgroup.HRQOL was measured with the Minnesota Living with Hear t Failure Questionnaire.The data were analyzed using chi-square,Spearman's correlation analysis,and independent t-test.Results:A number of 67 respondents participated in the recent study.The total mean scores of HRQOL were significantly different(P=0.001)between heart failure(HF)patients with reduced and preserved ejection fractions,41.07±7.54 and 54.97±4.36,respectively.It related with the physical(mean±standard deviation[SD]=10.4±2.14;t=-10.08,95%CI=-12.46 to-8.34;P-value=0.001)and psychological(mean±SD=3.5±0.5;t=-6.68,95%CI=-4.55 to-2.45;P-value=0.001)domain.Strong correlation was found between age(r=-0.898,P<0.05),NYHA functional classes(r=-0.858,P<0.01),duration of HF(r=-0.807,P<0.01),family support(r=0.927,P<0.01),and quality of life(Qo L).Conclusions:HRQOL in HF patients with reduced ejection fraction was higher than in those with preserved ejection fraction.Family suppor t is a fur ther determinant factor that has a positive correlation to the Qo L.

The impact of perceived social support, loneliness, and physical activity on quality of life in South Korean older adults

Purpose: The purpose of this study was to propose and test a conceptual model that explains the interrelationships among perceived social support, loneliness, physical activity(PA), and quality of life(QoL) among active older adults in South Korea.Methods: Data were collected from 332 individuals over the age of 65 using a systematic stratified convenience sampling method. Survey data were collected and analyzed using a structural equation model(SEM).Results: Perceived social support had a significantly positive effect on PA(b = 0.14, p < 0.01) and QoL(b = 0.28, p < 0.001) while decreasing loneliness(b = —0.55, p < 0.001). PA had a significant positive effect on QoL(b = 0.12, p < 0.01), and loneliness had a negative effect on QoL(b = —0.37, p < 0.001). Loneliness mediated the relationship between perceived social support and QoL.Conclusion: The SEM results of the current study support the proposed model that explained the interrelationships among perceived social support, loneliness, PA, and QoL among active older adults in South Korea. These findings suggest the importance of incorporating social support mechanisms for PA interventions in order to enhance QoL. The findings of this study can help create more effective health and physical education programs for the older generations in South Korea to enhance their QoL.

Donors’ Quality of Life after Live Liver Transplantation and Social Support: A Correlation Study

Objective: Donors’ quality of life (QOL) and social support were investigated in this study. Method: The SF-36 scale and social support scale were used to survey the quality of life and social support of donors of live liver transplantation. Result: The PCS (Physical Correlated Score) is 84.78 ± 13.21, the MCS (Mental Correlated Score) is 80.71 ± 14.65, and the total score is 165.49 ± 22.63. The results show the significant difference at GH (General Health) & VT (Vitality) domain regarding the age, P < 0.05;while there’s a significant difference at BP (Body Pain) domain regarding the sex, P < 0.05. The social support score of male & female donors are 37.75 ± 7.50 and 44.00 ± 4.30, and the difference is significant, P < 0.05. The MCS and the social support score are correlated, the correlation factor is 0.483, P < 0.05. Conclusion: There’s no significant difference between the donors and the normal population. The age is the risk factor of QOL, and it should be paid more attention when we select the donor. Excellent social support relates to high quality of life.

Health-related quality of life and perceived social support among cancer palliative patients in Saudi Arabia

Aim:This study aims to describe health-related quality of life(HRQL),identify factors associated with HRQL physical and mental health domains,and explore the association between perceived social supports and HRQL among cancer palliative patients in Saudi Arabia.Methods:A cross-sectional study is applied.The validated European Organization for Cancer Research and Treatment,the EORTC QLQ-15 palliative care scale and the Multidimensional Scale of Perceived Social Support(MSPSS)have been used.A convenience sample of(N=301)palliative cancer patients was collected from two main regional cancer centers in Riyadh.Data were analyzed using Pearson correlation analysis.Results:Results indicate that overall quality of life showed a significant positive correlation with perceived family and friend support,sub-factors of perceived social support.Regression analysis showed that the overall model experienced 69.0%of the variance for global health statutes with F(4,7)=7.149 P<0.001.Physical functioning,emotional functioning,and family support were found to be significant predictors of global health status.Family and Friend support were found to be significant positive predictors of emotional functioning.Conclusions:The inpatient and outpatient treatment can vary at different stages and in different areas,family and friend support has been highlighted as necessary in this context.Physical and emotional factors have been demonstrated in older age(geriatric)patients as they may have debilitating diseases that can limit their functioning hence support the case for more palliative care.

Factors influencing quality of life in Chinese patients with dementia: a systematic review

Background:Dementia is a group of nervous system diseases characterized by progressive cognitive decline,leading to a loss of self-care ability and a decline in well-being.This places a significant burden on the global healthcare system,with Chinese patients accounting for approximately one-quarter of the world’s dementia cases.Therefore,it is crucial to identify factors that impact the quality of life(QOL)among elderly Chinese individuals with dementia.Method:To achieve this,we conducted a comprehensive search of several databases,including PubMed,Embase,Web of Science,the Cochrane Library,China National Knowledge Infrastructure,Wanfang Data,China VIP Database and China Biomedical Literature Database.We reviewed cross-sectional studies from the inception of these databases until March 27,2022.QOL outcomes were assessed using standardized scales in the studies included in this review.Results:The search yielded a total of 1,235 relevant articles,from which we finally included 21 cross-sectional studies and one longitudinal study after rigorous quality assessment.Among these,10 studies were classified as high quality,while 12 were classified as fair quality.Through our analysis,we identified 28 patient-rated QOL factors and 14 caregiver-rated QOL factors.These factors were categorized into three groups:patient,disease-related and caregiver.Factors commonly found to influence patient-rated QOL included age,education,marital status,depression,self-care ability,dementia severity,cognitive function,behavioral and psychological symptoms of dementia and caregiver burden.Similarly,factors commonly influencing caregiver-rated QOL included economic status,depression,self-care ability,dementia severity,cognitive function,behavioral and psychological symptoms of dementia and caregiving time.Conclusion:This review clarifies the factors that influence the QOL of Chinese individuals with dementia.When implementing interventions,it is crucial to consider the differences between patient-rated QOL and caregiver-proxy-rated QOL,as well as their respective influencing factors.

Family empowerment and quality of life of parents raising children with Developmental Disabilities in 78 Japanese families

Objectives: The families of these children experience distress both at the time of diagnosis and afterward.A top priority is to understand family empowerment,family function,and family members' quality of life (QoL) and to effectively support these families in Japan.The objective of this study was to assess the actual conditions of families living with children having DDs and to explore the factors associated with family empowerment and parents' QoL.Methods: We surveyed ninety-three parents (78 mothers,15 fathers) from 78 families which lived with children with DDs in the capital region of Japan.We assessed two main outcomes using the Japanese versions of the following instruments: Family Empowerment Scale (FES),World Health Organization Quality of Life 26 (WHOQOL26),and other six outcomes.Correlation and multiple regression analyses were conducted.Results: No medication,cooperation with child rearing,assistance from a developmental support center,solved problems related to child rearing,and higher scores in Problem Solving contributed to higher FES scores.Higher WHOQOL26 scores were related to being a full-time housewife,higher self-esteem,no developmental support,a broad emotional support network,higher scores in Problem Solving and Role Function,and lower scores in Affective Reaction and General Function.Conclusions: We revealed that family empowerment and QoL of parents rearing children with DDs in Japan were affected by various subscales of family function and other family attributes.Effective interventions for improving family empowerment and QoL should be researched in the future.

A longitudinal study of quality of life among people living with a progressive neurological illness

This study investigated predictors of quality of life (QOL) of people with progressive neurological illnesses. Participants were 257 people with motor neurone disease (MND), Huntington’s disease (HD), multiple sclerosis (MS), or Parkinson’s. Participants completed questionnaires on two occasions, 12 months apart. There was an increase in severity of symptoms for people withMND, negative mood for people with HD and Parkinson’s, and social support satisfaction for people with MS. Regression analyses were conducted to determine predictors of QOL for each group. Predictor variables were length of illness, symptoms (physical symptoms, control over body, cognitive symptoms and psychological symptoms), mood, relationship satisfaction and social support. Predictors of QOL were severity of symptoms for people withMND, HD and MS;negative mood for people withMNDand Parkinson’s;and social support satisfaction for people with MS. These results demonstrate the importance of illness severity and mood in predicting QOL, but also indicate differences between illness groups. The limited role played by social support and relationship is a surprising finding from the current study.

Roles of mutual help of local community networks in community health activities: Improvement for the quality of life of older people in Thailand

Objectives: This study aimed to describe work and activities of community networks focusing on the improvement of the quality of life (QOL) of older people in Thailand.The understanding of the work can help enhancing the community development and strengthening of local communities and their networks.Methods: Qualitative methods including in-depth interview,observation,and focus group discussion were employed to the study.64 participants participated to the study and were recruited from 4 key actors within the community.Content analysis was used to analyze the obtained data.This study was conducted in 6 local administrative organizations (LAOs) which selected from the outstanding areas of the project.Each LAO represents one sub-district of the regions of Thailand namely;(1) the upper north,(2) the lower north,(3)the upper eastern,(4) the lower eastern,(5) the central and (6) the south.Results: The findings of this study were categorized into three main themes: (1) Social capital including people in the community,social groups,and organizations,(2) Mutual help/collaboration activities composed of six sets of activities related to social capitals working on the improvement of QOL of older people,and (3) Impacts of the mutual help/collaboration activities on older people and local communities who help to improve of QOL of older people.Conclusion: The findings are important features for the community development.These themes should be recommended for community nurses,health related groups and organizations for the improvement of QOL of older people in the community.

Quality of life among women with breast cancer living in Wuhan, China

Background:Quality of life is an important indicator in patients with breast cancer.Studies here reported that the quality of life in patients with breast cancer is low and many factors contribute to this poor quality of life.Purpose:To examine the relationships among demographic characteristics,optimism,social support,illness related factors,appraisal of illness,coping strategies and the quality of life of Chinese women with breast cancer residing in Wuhan,China.Methods:A convenience sample of 156 Chinese women with breast cancer was recruited from five teaching hospitals in Wuhan,China.Participants completed the Revised Life Orientation Test,the Perceived Social Support Scale,the Symptom Distress Scale,the Appraisal of Illness Scale,the Medical Coping Modes Questionnaire,and the Functional Assessment of Cancer Therapy-Breast.Path analysis was used to examine factors influencing quality of life.Results:Significant relationships were found between optimism,symptom distress,social support,appraisal of illness,a give-in coping mode and quality of life.Optimism,social support,symptom distress,lymph node status,appraisal of illness,and a give-in coping mode accounted for 66.6%of the variance in quality of life.Conclusions:The findings of this study underscore the importance of helping women reduce symptoms distress,appraise their illness positively,use less negative coping modes,and maintain optimism,maintain good social support,because all of these factors indirectly or directly affect their quality of life.

Health-related quality of life in Parkinson's disease patients in northeastern Sicily, Italy An ecological perspective

Parkinson＇s disease has a negative impact on health-related quality of life in Parkinson＇s disease patients. Depression, cognitive impairment, coping strategies, dyskinesia, gait disorders and complications of dopaminergic drugs are the variables that most affect health-related quality of life. The ecological model of human development focuses attention on both individual and social environmental factors as targets for health interventions. From this perspective, the aim of this cross-sectional survey was to evaluate the influence of gender, family size and perceived autonomy on health-related quality of life in Parkinson＇s disease patients in nOrtheastern Sicily, Italy. Ninety Parkinson＇s disease patients, attending the Movement Disorders Clinic at IRCCS Centro Neurolesi ＂Bonino-Pulejo＂ （Messina）, were consecutively enrolled. The Unified Parkinson Disease Rating Scale motor subscale （UPDRS-Ⅲ） scores, the Parkinson Disease Questionnaire-39 Item scores （as a disease-specific measure of health-related quality of life）, scores on the Short Form （36） Health Survey Questionnaire （as a generic measure）, and answers to a brief checklist were recorded. A total of 85 Parkinson＇s disease patients （49% males and 51% females; mean age 70.8 ± 8.6 years mean UPDRS-Ⅲ 24.15 ± 6.55; mean disease duration 5.52 ± 4.65 years） completed the booklet of questionnaires. In the multivariate regression analysis, we included clinical and social variables as independent predictors of health-related quality of life. Our results suggest a potential compounding effect of ecological intrapersonal and interpersonal levels on health-related quality of life outcomes. Gender, self-evaluated autonomy and family size significantly impacted health-related quality of life. If quality of life is used as an indicator of treatment outcomes, an ecological perspective of the case history will be important to disclose relevant prognostic information and trigger personalized health care interventions.

Mental and physical symptoms associated with lower social support for patients with hepatitis C

AIM: To systematically examine the impact of the hepatitis C virus (HCV) diagnosis on patients' level of social support in a large-scale study. METHODS: Patients evaluated and treated for HCV in a tertiary referral center were enrolled in a cross-sectional study. Demographic data, functional and emotional status as measured by the Hospital Anxiety and Depression Scale (HAD) and the Sickness Impact Profile (SIP), severity of liver disease, mode of acquisition, and physical and psychiatric comorbidities were collected from patients or abstracted from the medical record. All participants completed a semi-structured interview, addressing questions of social support. RESULTS: A total of 342 patients (mean age 45.2 years; 37% women) were enrolled. Ninety-two (27%) patients described lower levels of support by family and friends. Nearly half of the participants (45%) noted the loss of at least one relationship due to the disease. Fears related to transmitting the disease (25%) were common and often associated with ignorance or even discrimination by others (19%). Nearly one fifth of the patients did not share information about their disease with others to avoid being stigmatized. Lower levels of social support were significantly associated with living alone, being unemployed, being excluded from antiviral therapy, having psychiatric comorbidities, contracting HCV through intravenous drug use, having high levels of anxiety and depression as measured by the HAD and negative mood state as measured by the SIP. Patients reporting lower levels of social support also noted more physical symptoms as measured by the SIP. CONCLUSION: Patients with hepatitis C often face significant social problems, ranging from social isolation to familial stress. The most common concerns reflect a limited insight of patients and their relatives and friends about the disease, the risk factors for its spread, and about potential consequences. Our data suggest that educational interventions targeting support persons and the stressors identified in our findings may lessen or alleviate the social strains patients with hepatitis C experience.

老年冠心病患者疾病不确定感及社会支持与生活质量的相关性

目的 分析老年冠心病患者疾病不确定感及社会支持与生活质量的相关性。方法 回顾性分析2022年4月至2023年3月新疆医科大学第一附属医院心血管内科收治的150例老年冠心病患者的临床资料,包括一般人口学资料、Mishel疾病不确定感量表(MUIS)、社会支持量表及生活质量量表得分等。采用SPSS 26.0统计软件进行数据分析。计量资料比较采用独立样本t检验或方差分析。采用Pearson相关性分析对老年冠心病患者疾病不确定感及社会支持与生活质量的相关性进行分析。采用logistic回归分析老年冠心病患者生活质量的影响因素。结果 150例老年冠心病患者疾病不确定感得分为(119.76±12.85)分,社会支持得分为(61.83±5.42)分,生活质量得分为(63.91±6.28)分。老年冠心病患者生活质量得分在文化程度、家庭人均月收入、治疗缴费方式方面比较,差异有统计学意义(P<0.05)。老年冠心病患者生活质量得分与疾病不确定感得分呈负相关(r=-0.501;P<0.05),与社会支持得分呈正相关(r=0.457;P<0.05)。文化程度(OR=2.824,95%CI 1.343~5.935)、家庭人均月收入(OR=2.751,95%CI 1.345~5.626)、治疗缴费方式(OR=2.702,95%CI 1.379~5.292)、疾病不确定感(OR=3.111,95%CI 1.474~6.565)及社会支持(OR=2.933,95%CI 1.451~5.928)是老年冠心病患者生活质量的影响因素。结论 老年冠心病患者生活质量偏低,且与疾病不确定感、社会支持存在相关性,可针对老年冠心病患者生活质量的影响因素对患者进行干预,以提高患者生活质量。

Patients after colostomy： relationship between quality of life and acceptance of disability and social support

Background The aim of this research was to explore quality of life （QOL） and acceptance of disability and social support of colostomy patients as well as the relationship between these factors. Methods A descriptive, correlational study was conducted using four scales： the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire （EORTC QLQ-C30） and European Organization for Research and Treatment of Cancer Colorectal Cancer-Specific Quality of Life Questionnaire （EORTC QLQ-CR38） scales, the Acceptance of Disability Scale （ADS）, and the Social Relational Quality Scale （SRQS）. A convenience sample of 111 colostomy patients from four hospitals in Guangzhou who underwent colostomy operation at least one month prior to the study and who visited the stoma clinic or association from August 2011 to February 2012 was evaluated for inclusion in the study. All statistical analyses were performed using SPSS 17.0 software （SPSS Inc., Chicago, IL, USA）.

休闲活动对城市老年慢病患者生命质量的影响——基于社会支持、慢病数量的中介与调节作用分析

老年人患慢性病比例的上升使得我国人均预期寿命与老年人口平均健康寿命的差距不断扩大。利用2021年西安市老年慢病患者文化活动参与调查数据,通过有调节的中介效应模型,分析了社会支持及慢病数量在不同类型休闲活动对城市老年慢病患者生命质量影响中的作用机制。结果表明,个体休闲活动、团体休闲活动和社会支持对城市老年慢病患者生命质量具有显著提升作用。社会支持在团体休闲活动与生命质量之间起完全中介作用,同时,慢病数量在城市老年慢病患者“团体休闲活动-社会支持”和“社会支持-生命质量”影响路径中起调节作用。研究结果强调了改善社区休闲活动参与环境和构建多层次老年慢病患者社会支持网络对提升城市居民健康寿命的重要性。

感染科护士专业生活品质现状及影响因素研究

目的了解感染科护士专业生活品质现状并分析其影响因素,为采取针对性措施提高其专业生活品质提供参考。方法便利选取湖北省11所三甲医院的388名感染科护士,采用一般资料调查表、专业生活品质量表、领悟社会支持量表、自我同情简表进行调查。结果感染科护士专业生活品质量表中倦怠、二次创伤和共情满意维度得分分别为(26.16±5.90)分、(22.42±4.91)分、(30.26±8.16)分。回归分析结果显示,职称、每日工作时长、收入满意度、饮食状况、自评身体状况、社会支持和自我同情是倦怠的影响因素;独生子女、学历和自我同情是二次创伤的影响因素;独生子女、工作年限、收入满意度、饮食状况、自评身体状况、社会支持和自我同情是共情满意的影响因素(均P<0.05)。结论感染科护士的专业生活品质处于中等水平,影响因素较多。建议针对感染科护士的不同特征提供个性化的支持方案,以提高其专业生活品质。

乌鲁木齐市社区老年人衰弱现状及其影响因素

目的探讨乌鲁木齐市社区老年人衰弱现状及其影响因素。方法采用便利抽样法,选取新疆乌鲁木齐市水磨沟区的223例老年人作为研究对象,采用基本信息资料调查问卷、ADLs量表、MMSE量表、GDS-15量表、SSRS量表和SF-36量表进行问卷调查,应用单因素分析和二分类logistic回归分析老年衰弱人群的影响因素。结果社区老年人群衰弱发生率为12.11%(27/223)。单因素分析结果显示:衰弱与非衰弱患者年龄、家庭收入、医疗费用支付方式、患疾病种类、SSRS得分、GDS-15得分及SF-36量表中的情感职能、社会功能得分比较差异有统计学意义(P均<0.05)。二分类logistic回归分析结果显示,年龄、患疾病种类(≥2种)、抑郁是衰弱发生的危险因素(P均<0.05),家庭收入(≥2000元)、医保、社会支持(客观支持、主观支持和对社会支持的利用度)、情感职能、社会功能是衰弱发生的保护因素(P均<0.05)。结论乌鲁木齐市社区老年人衰弱发生率较高,年龄、患疾病种类、抑郁、家庭收入、医保、社会支持、情感职能、社会功能是衰弱发生的影响因素。

急性淋巴细胞白血病患儿父母养育倦怠现状及影响因素

目的 探讨急性淋巴细胞白血病患儿父母养育倦怠现状及影响因素,为临床针对性护理干预提供参考。方法 采用一般资料问卷、养育倦怠评估量表、疾病不确定感量表和领悟社会支持量表对广州市4所三级甲等医院收治的259例急性淋巴细胞白血病患儿的父母进行调查。结果 患儿父母养育倦怠得分为(90.19±14.25)分;患儿疾病严重程度、与患儿关系、家庭人均月收入、疾病不确定感总分、领悟社会支持总分是养育倦怠的主要影响因素(均P<0.05),可解释总变异的50.9%。结论 急性淋巴细胞白血病患儿父母存在养育倦怠,给予患儿疾病严重程度高、患儿母亲、家庭人均月收入低的患儿父母更多关注,降低其疾病不确定感并提高其领悟社会支持水平,从而降低其养育倦怠水平。