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HEPATITIS C VIRUS AND INTRAVENOUS DRUG MISUSE: A MODELING APPROACH
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作者 STEADY MUSItAYABASA CLAVER P. BHUNU 《International Journal of Biomathematics》 2014年第1期107-128,共22页
Hepatitis C virus (HCV) is a blood-borne infection that can lead to progressive liver fail- ure, cirrhosis, hepatocellular carcinoma and death. A deterministic mathematical model for assessing the impact of daily in... Hepatitis C virus (HCV) is a blood-borne infection that can lead to progressive liver fail- ure, cirrhosis, hepatocellular carcinoma and death. A deterministic mathematical model for assessing the impact of daily intravenous drug misuse on the transmission dynamics of HCV is presented and analyzed. A threshold quantity known as the reproductive number has been computed. Stability of the steady states has been investigated. The dynamical analysis reveals that the model has globally asymptotically stable steady states. The impact of daily intravenous drug misuse on the transmission dynamics of HCV has been discussed through the basic reproductive number and numerical simulations. 展开更多
关键词 HCV intravenous drug misuse minimal intravenous drug misusers heavy intravenous drug misusers treatment reproductive number sensitivity analysis.
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