Hepatitis C virus (HCV) is a blood-borne infection that can lead to progressive liver fail- ure, cirrhosis, hepatocellular carcinoma and death. A deterministic mathematical model for assessing the impact of daily in...Hepatitis C virus (HCV) is a blood-borne infection that can lead to progressive liver fail- ure, cirrhosis, hepatocellular carcinoma and death. A deterministic mathematical model for assessing the impact of daily intravenous drug misuse on the transmission dynamics of HCV is presented and analyzed. A threshold quantity known as the reproductive number has been computed. Stability of the steady states has been investigated. The dynamical analysis reveals that the model has globally asymptotically stable steady states. The impact of daily intravenous drug misuse on the transmission dynamics of HCV has been discussed through the basic reproductive number and numerical simulations.展开更多
文摘Hepatitis C virus (HCV) is a blood-borne infection that can lead to progressive liver fail- ure, cirrhosis, hepatocellular carcinoma and death. A deterministic mathematical model for assessing the impact of daily intravenous drug misuse on the transmission dynamics of HCV is presented and analyzed. A threshold quantity known as the reproductive number has been computed. Stability of the steady states has been investigated. The dynamical analysis reveals that the model has globally asymptotically stable steady states. The impact of daily intravenous drug misuse on the transmission dynamics of HCV has been discussed through the basic reproductive number and numerical simulations.