Among the popular mixed drugs in China,the oral solution shenxianshui and the floury drug milk tea have recently emerged.In 2014,123 bags of milk tea included in 14 cases were tested qualitatively and quantitatively,a...Among the popular mixed drugs in China,the oral solution shenxianshui and the floury drug milk tea have recently emerged.In 2014,123 bags of milk tea included in 14 cases were tested qualitatively and quantitatively,and the test results provided a basis for drug detection,prosecution,and sentencing.More than two drug components were detected in milk tea,which was characterized as a fragrant beige,yellow,or brown powder.The detection rates of methylamphetamine(MA),3,4-methylenedioxymethamphetamine(MDMA),and ketamine in milk tea were 36.6%,50.4%,and 76.4%,respectively,and the concentrations of MA,MDMA,and ketamine were 0.2-5.1,3.2-30.1,and 0.8-176.3 mg/g,respectively,in quantitative testing.展开更多
The ^1 H nuclear magnetic resonance （^1 H NMR） fingerprints of fractionated non-polar extracts （control substance for a plant drug （CSPD） A） from Rhizoma chuanxiong, the rhizomes of Ligusticum chuanxiong Hort., ...The ^1 H nuclear magnetic resonance （^1 H NMR） fingerprints of fractionated non-polar extracts （control substance for a plant drug （CSPD） A） from Rhizoma chuanxiong, the rhizomes of Ligusticum chuanxiong Hort., of seven specimens from different sources were measured on Fourier Transform （FT）-NMR spectrometer and assigned by comparing them with the ^1 H NMR spectra of the isolated pure compounds. The ^1 H NMR fingerprints showed exclusively characteristic resonance signals of the major special constituents of the plant. Although the differences in the relative intensity of the ^1H NMR signals due to a discrepancy in the ratio of the major constituents among these samples could be confirmed by high performance liquid chromatography analysis, the general features of the ^1H NMR fingerprint established for an authentic sample of the rhizomes of L. chuanxiong e. hibited exclusive data from those special compounds and can be used for authenticating L. Chuanxiong species.展开更多
文摘Among the popular mixed drugs in China,the oral solution shenxianshui and the floury drug milk tea have recently emerged.In 2014,123 bags of milk tea included in 14 cases were tested qualitatively and quantitatively,and the test results provided a basis for drug detection,prosecution,and sentencing.More than two drug components were detected in milk tea,which was characterized as a fragrant beige,yellow,or brown powder.The detection rates of methylamphetamine(MA),3,4-methylenedioxymethamphetamine(MDMA),and ketamine in milk tea were 36.6%,50.4%,and 76.4%,respectively,and the concentrations of MA,MDMA,and ketamine were 0.2-5.1,3.2-30.1,and 0.8-176.3 mg/g,respectively,in quantitative testing.
基金Supported by the National Natural Science Foundation of China (30630073)the Science Foundation of the State Administration of Traditional ChineseMedicine, China (02-03ZP09)
文摘The ^1 H nuclear magnetic resonance （^1 H NMR） fingerprints of fractionated non-polar extracts （control substance for a plant drug （CSPD） A） from Rhizoma chuanxiong, the rhizomes of Ligusticum chuanxiong Hort., of seven specimens from different sources were measured on Fourier Transform （FT）-NMR spectrometer and assigned by comparing them with the ^1 H NMR spectra of the isolated pure compounds. The ^1 H NMR fingerprints showed exclusively characteristic resonance signals of the major special constituents of the plant. Although the differences in the relative intensity of the ^1H NMR signals due to a discrepancy in the ratio of the major constituents among these samples could be confirmed by high performance liquid chromatography analysis, the general features of the ^1H NMR fingerprint established for an authentic sample of the rhizomes of L. chuanxiong e. hibited exclusive data from those special compounds and can be used for authenticating L. Chuanxiong species.
