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Seismic modeling by combining the finite-difference scheme with the numerical dispersion suppression neural network
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作者 Hong-Yong Yan 《Petroleum Science》 SCIE EI CAS CSCD 2024年第5期3157-3165,共9页
Seismic finite-difference(FD) modeling suffers from numerical dispersion including both the temporal and spatial dispersion, which can decrease the accuracy of the numerical modeling. To improve the accuracy and effic... Seismic finite-difference(FD) modeling suffers from numerical dispersion including both the temporal and spatial dispersion, which can decrease the accuracy of the numerical modeling. To improve the accuracy and efficiency of the conventional numerical modeling, I develop a new seismic modeling method by combining the FD scheme with the numerical dispersion suppression neural network(NDSNN). This method involves the following steps. First, a training data set composed of a small number of wavefield snapshots is generated. The wavefield snapshots with the low-accuracy wavefield data and the high-accuracy wavefield data are paired, and the low-accuracy wavefield snapshots involve the obvious numerical dispersion including both the temporal and spatial dispersion. Second, the NDSNN is trained until the network converges to simultaneously suppress the temporal and spatial dispersion.Third, the entire set of low-accuracy wavefield data is computed quickly using FD modeling with the large time step and the coarse grid. Fourth, the NDSNN is applied to the entire set of low-accuracy wavefield data to suppress the numerical dispersion including the temporal and spatial dispersion.Numerical modeling examples verify the effectiveness of my proposed method in improving the computational accuracy and efficiency. 展开更多
关键词 Finite difference Seismic modeling Numerical dispersion suppression Computational accuracy Computational efficiency
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The Precise Finite Difference Method for Seismic Modeling 被引量:11
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作者 WangRunqiut JiaXiaofeng HuTlanyue 《Applied Geophysics》 SCIE CSCD 2004年第2期69-74,共6页
D seismic modeling can be used to study the propagation of seismic wave exactly and it is also a tool of 3-D seismic data processing and interpretation. In this paper the arbitrary difference and precise integration a... D seismic modeling can be used to study the propagation of seismic wave exactly and it is also a tool of 3-D seismic data processing and interpretation. In this paper the arbitrary difference and precise integration are used to solve seismic wave equation, which means difference scheme for space domain and analytic integration for time domain. Both the principle and algorithm of this method are introduced in the paper. Based on the theory, the numerical examples prove that this hybrid method can lead to higher accuracy than the traditional finite difference method and the solution is very close to the exact one. Also the seismic modeling examples show the good performance of this method even in the case of complex surface conditions and complicated structures. 展开更多
关键词 modelING wave equation finite difference arbitrary difference precise integration
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Irregular surface seismic forward modeling by a body-fitted rotated–staggered-grid finite-difference method 被引量:4
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作者 Cheng Jing-Wang Fan Na +1 位作者 Zhang You-Yuan Lü Xiao-Chun 《Applied Geophysics》 SCIE CSCD 2018年第3期420-431,共12页
Finite-difference(FD) methods are widely used in seismic forward modeling owing to their computational efficiency but are not readily applicable to irregular topographies. Thus, several FD methods based on the transfo... Finite-difference(FD) methods are widely used in seismic forward modeling owing to their computational efficiency but are not readily applicable to irregular topographies. Thus, several FD methods based on the transformation to curvilinear coordinates using body-fitted grids have been proposed, e.g., stand staggered grid(SSG) with interpolation, nonstaggered grid, rotated staggered grid(RSG), and fully staggered. The FD based on the RSG is somewhat superior to others because it satisfies the spatial distribution of the wave equation without additional memory and computational requirements; furthermore, it is simpler to implement. We use the RSG FD method to transform the firstorder stress–velocity equation in the curvilinear coordinates system and introduce the highprecision adaptive, unilateral mimetic finite-difference(UMFD) method to process the freeboundary conditions of an irregular surface. The numerical results suggest that the precision of the solution is higher than that of the vacuum formalism. When the minimum wavelength is low, UMFD avoids the surface wave dispersion. We compare FD methods based on RSG, SEM, and nonstaggered grid and infer that all simulation results are consistent but the computational efficiency of the RSG FD method is higher than the rest. 展开更多
关键词 FINITE difference FORWARD modeling GRID staggered rotated body-fitted SURFACE free BOUNDARY
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Numerical modeling of wave equation by a truncated high-order finite-difference method 被引量:4
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作者 Yang Liu Mrinal K. Sen 《Earthquake Science》 CSCD 2009年第2期205-213,共9页
Finite-difference methods with high-order accuracy have been utilized to improve the precision of numerical solution for partial differential equations. However, the computation cost generally increases linearly with ... Finite-difference methods with high-order accuracy have been utilized to improve the precision of numerical solution for partial differential equations. However, the computation cost generally increases linearly with increased order of accuracy. Upon examination of the finite-difference formulas for the first-order and second-order derivatives, and the staggered finite-difference formulas for the first-order derivative, we examine the variation of finite-difference coefficients with accuracy order and note that there exist some very small coefficients. With the order increasing, the number of these small coefficients increases, however, the values decrease sharply. An error analysis demonstrates that omitting these small coefficients not only maintain approximately the same level of accuracy of finite difference but also reduce computational cost significantly. Moreover, it is easier to truncate for the high-order finite-difference formulas than for the pseudospectral for- mulas. Thus this study proposes a truncated high-order finite-difference method, and then demonstrates the efficiency and applicability of the method with some numerical examples. 展开更多
关键词 finite difference high-order accuracy TRUNCATION EFFICIENCY numerical modeling
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Flow difference effect in the lattice hydrodynamic model 被引量:3
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作者 田钧方 贾斌 +1 位作者 李新刚 高自友 《Chinese Physics B》 SCIE EI CAS CSCD 2010年第4期31-36,共6页
In this paper, a new lattice hydrodynamic model based on Nagatani's model INagatani T 1998 Physica A 261 5991 is presented by introducing the flow difference effect. The stability condition for the new model is obtai... In this paper, a new lattice hydrodynamic model based on Nagatani's model INagatani T 1998 Physica A 261 5991 is presented by introducing the flow difference effect. The stability condition for the new model is obtained by using the linear stability theory. The result shows that considering the flow difference effect leads to stabilization of the system compared with the original lattice hydrodynamic model. The jamming transitions among the freely moving phase, the coexisting phase, and the uniform congested phase are studied by nonlinear analysis. The modified KdV equation near the critical point is derived to describe the traffic jam, and kink -antikink soliton solutions related to the traffic density waves are obtained. The simulation results are consistent with the theoretical analysis for the new model. 展开更多
关键词 lattice hydrodynamic model traffic flow flow difference
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Dynamic optimal allocation of energy storage systems integrated within photovoltaic based on a dual timescale dynamics model
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作者 Kecun Li Zhenyu Huang +2 位作者 Youbo Liu Yaser Qudaih Junyong Liu 《Global Energy Interconnection》 EI CSCD 2024年第4期415-428,共14页
Energy storage systems(ESSs)operate as independent market participants and collaborate with photovoltaic(PV)generation units to enhance the flexible power supply capabilities of PV units.However,the dynamic variations... Energy storage systems(ESSs)operate as independent market participants and collaborate with photovoltaic(PV)generation units to enhance the flexible power supply capabilities of PV units.However,the dynamic variations in the profitability of ESSs in the electricity market are yet to be fully understood.This study introduces a dual-timescale dynamics model that integrates a spot market clearing(SMC)model into a system dynamics(SD)model to investigate the profit-aware capacity growth of ESSs and compares the profitability of independent energy storage systems(IESSs)with that of an ESS integrated within a PV(PV-ESS).Furthermore,this study aims to ascertain the optimal allocation of the PV-ESS.First,SD and SMC models were set up.Second,the SMC model simulated on an hourly timescale was incorporated into the SD model as a subsystem,a dual-timescale model was constructed.Finally,a development simulation and profitability analysis was conducted from 2022 to 2040 to reveal the dynamic optimal range of PV-ESS allocation.Additionally,negative electricity prices were considered during clearing processes.The simulation results revealed differences in profitability and capacity growth between IESS and PV-ESS,helping grid investors and policymakers to determine the boundaries of ESSs and dynamic optimal allocation of PV-ESSs. 展开更多
关键词 Optimal allocation Profitability analysis PHOTOVOLTAIC Energy storage system dual timescale dynamics model Spot market clearing
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Second-order difference scheme for a nonlinear model of wood drying process
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作者 姜明杰 孙志忠 《Journal of Southeast University(English Edition)》 EI CAS 2006年第4期582-588,共7页
A numerical simulation for a model of wood drying process is considered. The model is given by a couple of nonlinear differential equations. One is a nonlinear parabolic equation and the other one is a nonlinear ordin... A numerical simulation for a model of wood drying process is considered. The model is given by a couple of nonlinear differential equations. One is a nonlinear parabolic equation and the other one is a nonlinear ordinary equation. A difference scheme is derived by the method of reduction of order. First, a new variable is introduced and the original problem is rewritten into a system of the first-order differential equations. Secondly, a difference scheme is constructed for the later problem. The solvability, stability and convergence of the difference scheme are proved by the energy method. The convergence order of the difference scheme is secondorder both in time and in space. A prior error estimate is put forward. The new variable is put aside to reduce the computational cost. A numerical example testifies the theoretical result. 展开更多
关键词 wood drying process model nonlinear differential equation difference scheme method of reduction of order STABILITY CONVERGENCE
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Effect of strain rate difference between inside and outside groove in M-K model on prediction of forming limit curve of Ti6Al4V at elevated temperatures 被引量:4
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作者 Xiao-qiang LI Hong-rui DONG +2 位作者 Hai-bo WANG Gui-qiang GUO Dong-sheng LI 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2020年第2期405-416,共12页
The influence of initial groove angle on strain rate inside and outside groove of Ti6Al4V alloy was investigated.Based on the evolution of strain rate inside and outside groove,the effect of strain rate difference on ... The influence of initial groove angle on strain rate inside and outside groove of Ti6Al4V alloy was investigated.Based on the evolution of strain rate inside and outside groove,the effect of strain rate difference on the evolution of normal stress and effective stress inside and outside groove was also analyzed.The results show that when linear loading path changes from uniaxial tension to equi-biaxial tension,the initial groove angle plays a weaker role in the evolution of strain rate in the M-K model.Due to the constraint of force equilibrium between inside and outside groove,the strain rate difference makes the normal stress inside groove firstly decrease and then increase during calculation,which makes the prediction algorithm of forming limit convergent at elevated temperature.The decrease of normal stress inside groove is mainly caused by high temperature softening effect and the rotation of groove,while the increase of normal stress inside groove is mainly due to strain rate hardening effect. 展开更多
关键词 Ti6Al4V alloy strain rate difference forming limit M-K model stress evolution
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A novel small-signal equivalent circuit model for GaN HEMTs incorporating a dual-field-plate
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作者 Jinye Wang Jun Liu Zhenxin Zhao 《Journal of Semiconductors》 EI CAS CSCD 2024年第5期61-68,共8页
An accurate and novel small-signal equivalent circuit model for GaN high-electron-mobility transistors(HEMTs)is proposed,which considers a dual-field-plate(FP)made up of a gate-FP and a source-FP.The equivalent circui... An accurate and novel small-signal equivalent circuit model for GaN high-electron-mobility transistors(HEMTs)is proposed,which considers a dual-field-plate(FP)made up of a gate-FP and a source-FP.The equivalent circuit of the overall model is composed of parasitic elements,intrinsic transistors,gate-FP,and source-FP networks.The equivalent circuit of the gate-FP is identical to that of the intrinsic transistor.In order to simplify the complexity of the model,a series combination of a resistor and a capacitor is employed to represent the source-FP.The analytical extraction procedure of the model parameters is presented based on the proposed equivalent circuit.The verification is carried out on a 4×250μm GaN HEMT device with a gate-FP and a source-FP in a 0.45μm technology.Compared with the classic model,the proposed novel small-signal model shows closer agreement with measured S-parameters in the range of 1.0 to 18.0 GHz. 展开更多
关键词 small-signal model dual field-plate(FP) GaN high-electron-mobility transistors(HEMT) parameter extraction
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An approach to estimate tree height using PolInSAR data constructed by the Sentinel-1 dual-pol SAR data and RVoG model
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作者 Yin Zhang Ding-Feng Duan 《Journal of Electronic Science and Technology》 EI CAS CSCD 2024年第3期69-79,共11页
We estimate tree heights using polarimetric interferometric synthetic aperture radar(PolInSAR)data constructed by the dual-polarization(dual-pol)SAR data and random volume over the ground(RVoG)model.Considering the Se... We estimate tree heights using polarimetric interferometric synthetic aperture radar(PolInSAR)data constructed by the dual-polarization(dual-pol)SAR data and random volume over the ground(RVoG)model.Considering the Sentinel-1 SAR dual-pol(SVV,vertically transmitted and vertically received and SVH,vertically transmitted and horizontally received)configuration,one notes that S_(HH),the horizontally transmitted and horizontally received scattering element,is unavailable.The S_(HH)data were constructed using the SVH data,and polarimetric SAR(PolSAR)data were obtained.The proposed approach was first verified in simulation with satisfactory results.It was next applied to construct PolInSAR data by a pair of dual-pol Sentinel-1A data at Duke Forest,North Carolina,USA.According to local observations and forest descriptions,the range of estimated tree heights was overall reasonable.Comparing the heights with the ICESat-2 tree heights at 23 sampling locations,relative errors of 5 points were within±30%.Errors of 8 points ranged from 30%to 40%,but errors of the remaining 10 points were>40%.The results should be encouraged as error reduction is possible.For instance,the construction of PolSAR data should not be limited to using SVH,and a combination of SVH and SVV should be explored.Also,an ensemble of tree heights derived from multiple PolInSAR data can be considered since tree heights do not vary much with time frame in months or one season. 展开更多
关键词 Constructed polarimetric SAR data dual polarization Sentinel-1 SAR data Polarimetric interferometric SAR Random volume over the ground model Tree height estimation
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A geometrically and locally adaptive remeshing method for finite difference modeling of mining-induced surface subsidence 被引量:1
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作者 Ziyu Zhang Gang Mei Nengxiong Xu 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2022年第1期219-231,共13页
Surface subsidence induced by underground mining is a typical serious geohazard.Numerical approaches such as the discrete element method(DEM)and finite difference method(FDM)have been widely used to model and analyze ... Surface subsidence induced by underground mining is a typical serious geohazard.Numerical approaches such as the discrete element method(DEM)and finite difference method(FDM)have been widely used to model and analyze mining-induced surface subsidence.However,the DEM is typically computationally expensive,and is not capable of analyzing large-scale problems,while the mesh distortion may occur in the FDM modeling of largely deformed surface subsidence.To address the above problems,this paper presents a geometrically and locally adaptive remeshing method for the FDM modeling of largely deformed surface subsidence induced by underground mining.The essential ideas behind the proposed method are as follows:(i)Geometrical features of elements(i.e.the mesh quality),rather than the calculation errors,are employed as the indicator for determining whether to conduct the remeshing;and(ii)Distorted meshes with multiple attributes,rather than those with only a single attribute,are locally regenerated.In the proposed method,the distorted meshes are first adaptively determined based on the mesh quality,and then removed from the original mesh model.The tetrahedral mesh in the distorted area is first regenerated,and then the physical field variables of old mesh are transferred to the new mesh.The numerical calculation process recovers when finishing the regeneration and transformation.To verify the effectiveness of the proposed method,the surface deformation of the Yanqianshan iron mine,Liaoning Province,China,is numerically investigated by utilizing the proposed method,and compared with the numerical results of the DEM modeling.Moreover,the proposed method is applied to predicting the surface subsidence in Anjialing No.1 Underground Mine,Shanxi Province,China. 展开更多
关键词 Mining-induced subsidence Numerical modeling Finite difference method(FDM) Distorted mesh Adaptive remeshing
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Difference-frequency ultrasound generation from microbubbles under dual-frequency excitation 被引量:1
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作者 马青玉 邱媛媛 +2 位作者 黄蓓 章东 龚秀芬 《Chinese Physics B》 SCIE EI CAS CSCD 2010年第9期437-442,共6页
The difference-frequency (DF) ultrasound generated by using parametric effect promises to improve detection depth owing to its low attenuation, which is beneficial for deep tissue imaging. With ultrasound contrast a... The difference-frequency (DF) ultrasound generated by using parametric effect promises to improve detection depth owing to its low attenuation, which is beneficial for deep tissue imaging. With ultrasound contrast agents infusion, the harmonic components scattered from the microbubbles, including DF, can be generated due to the nonlinear vibration. A theoretical study on the DF generation from microbubbles under the dual-frequency excitation is proposed in formula based on the solution of the RPNNP equation. The optimisation of the DF generation is discussed associated with the applied acoustic pressure, frequency, and the microbubble size. Experiments are performed to validate the theoretical predictions by using a dual-frequency signal to excite microbubbles. Both the numerical and experimental results demonstrate that the optimised DF ultrasound can be achieved as the difference frequency is close to the resonance frequency of the microbubble and improve the contrast-to-tissue ratio in imaging. 展开更多
关键词 difference-frequency MICROBUBBLE dual-frequency excitation parametric effect
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ON LINEARIZED FINITE DIFFERENCE SIMULATION FOR THE MODEL OF NUCLEAR REACTOR DYNAMICS
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作者 孙志忠 杨梅 +1 位作者 石佩虎 陈绍炳 《Numerical Mathematics A Journal of Chinese Universities(English Series)》 SCIE 2000年第2期159-174,共16页
The model of nuclear reactor dynamics is an initial-boundary value problems of a cou- pled nonlinear integrodifferential equation system of one ordinary differential equation and one par-- tial differential equation. ... The model of nuclear reactor dynamics is an initial-boundary value problems of a cou- pled nonlinear integrodifferential equation system of one ordinary differential equation and one par-- tial differential equation. In this this,paper,a linearized difference scheme is derived by the method of reduction of order.It is proved that the scheme is uniquely solvable and unconditionally convergent with the convergence rate of order two both in discrete H1norm and in discrete maxinum narm,and one needs only to solve a tridiagonal system of linear algebraic equations at each time lev- el.The method of reduction of order is an indirect constructing-difference-scheme method,which aim is for the analysis of solvablity and convergence of the constructed difference scheme. 展开更多
关键词 model of muclear reactor DYNAMICS differential EQUATIONS difference scheme nu- merical SIMULATION convergence nonlinear.
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The time-dependent Ginzburg-Landau equation for the two-velocity difference model
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作者 吴淑贞 程荣军 葛红霞 《Chinese Physics B》 SCIE EI CAS CSCD 2011年第8期130-135,共6页
A thermodynamic theory is formulated to describe the phase transition and critical phenomenon in traffic flow. Based on the two-velocity difference model, the time-dependent Ginzburg-Landau (TDGL) equation under cer... A thermodynamic theory is formulated to describe the phase transition and critical phenomenon in traffic flow. Based on the two-velocity difference model, the time-dependent Ginzburg-Landau (TDGL) equation under certain condition is derived to describe the traffic flow near the critical point through the nonlinear analytical method. The corresponding two solutions, the uniform and the kink solutions, are given. The coexisting curve, spinodal line and critical point are obtained by the first and second derivatives of the thermodynamic potential. The modified Korteweg- de Vries (mKdV) equation around the critical point is derived by using the reductive perturbation method and its kink antikink solution is also obtained. The relation between the TDGL equation and the mKdV equation is shown. The simulation result is consistent with the nonlinear analytical result. 展开更多
关键词 traffic flow two-velocity difference model TDGL equation mKdV equation
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Multiple flux difference effect in the lattice hydrodynamic model
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作者 Wang Tao Gao Zi-You Zhao Xiao-Mei 《Chinese Physics B》 SCIE EI CAS CSCD 2012年第2期210-217,共8页
Considering the effect of multiple flux difference, an extended lattice model is proposed to improve the stability of traffic flow. The stability condition of the new model is obtained by using linear stability theory... Considering the effect of multiple flux difference, an extended lattice model is proposed to improve the stability of traffic flow. The stability condition of the new model is obtained by using linear stability theory. The theoretical analysis result shows that considering the flux difference effect ahead can stabilize traffic flow. The nonlinear analysis is also conducted by using a reduetive perturbation method. The modified KdV (mKdV) equation near the critical point is derived and the kink antikink solution is obtained from the mKdV equation. Numerical simulation results show that the multiple flux difference effect can suppress the traffic jam considerably, which is in line with the analytical result. 展开更多
关键词 flux difference lattice hydrodynamic model traffic flow mKdV equation
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A new control method based on the lattice hydrodynamic model considering the double flux difference
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作者 Shunda Qin Hongxia Ge Rongjun Cheng 《Chinese Physics B》 SCIE EI CAS CSCD 2018年第5期131-136,共6页
A new feedback control method is derived based on the lattice hydrodynamic model in a single lane. A signal based on the double flux difference is designed in the lattice hydrodynamic model to suppress the traffic jam... A new feedback control method is derived based on the lattice hydrodynamic model in a single lane. A signal based on the double flux difference is designed in the lattice hydrodynamic model to suppress the traffic jam. The stability of the model is analyzed by using the new control method. The advantage of the new model with and without the effect of double flux difference is explored by the numerical simulation. The numerical simulations demonstrate that the traffic jam can be alleviated by the control signal. 展开更多
关键词 traffic flow lattice hydrodynamic model control method double flux difference
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Modeling Dynamic Systems by Using the Nonlinear Difference Equations Based on Genetic Programming
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作者 Liu Mm, Hu Bao-qingSchool of Mathematics and Statistics, Wuhan University, Wuhan 430072, Hubei, China 《Wuhan University Journal of Natural Sciences》 CAS 2003年第S1期243-248,共6页
When acquaintances of a model are little or the model is too complicate to build by using traditional time series methods, it is convenient for us to take advantage of genetic programming (GP) to build the model. Cons... When acquaintances of a model are little or the model is too complicate to build by using traditional time series methods, it is convenient for us to take advantage of genetic programming (GP) to build the model. Considering the complexity of nonlinear dynamic systems, this paper proposes modeling dynamic systems by using the nonlinear difference e-quation based on GP technique. First it gives the method, criteria and evaluation of modeling. Then it describes the modeling algorithm using GP. Finally two typical examples of time series are used to perform the numerical experiments. The result shows that this algorithm can successfully establish the difference equation model of dynamic systems and its predictive result is also satisfactory. 展开更多
关键词 dynamic systems the model of difference equation genetic programming
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Flow difference effect in the two-lane lattice hydrodynamic model
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作者 王涛 高自友 +2 位作者 赵小梅 田钧方 张文义 《Chinese Physics B》 SCIE EI CAS CSCD 2012年第7期207-215,共9页
By introducing a flow difference effect, a modified lattice two-lane traffic flow model is proposed, which is proved to be capable of improving the stability of traffic flow. Both the linear stability condition and th... By introducing a flow difference effect, a modified lattice two-lane traffic flow model is proposed, which is proved to be capable of improving the stability of traffic flow. Both the linear stability condition and the kink-antikink solution derived from the modified Korteweg-de Vries (mKdV) equation are analyzed. Numerical simulations verify the theoretical analysis. Futhermore, the evolution laws under different disturbances in the metastable region are studied. 展开更多
关键词 traffic flow flow difference lattice hydrodynamic model modified Korteweg-de VriesKdV equation
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Finite Difference Method of Modelling Groundwater Flow
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作者 Magnus.U. Igboekwe N. J. Achi 《Journal of Water Resource and Protection》 2011年第3期192-198,共7页
In this study, finite difference method is used to solve the equations that govern groundwater flow to obtain flow rates, flow direction and hydraulic heads through an aquifer. The aim therefore is to discuss the prin... In this study, finite difference method is used to solve the equations that govern groundwater flow to obtain flow rates, flow direction and hydraulic heads through an aquifer. The aim therefore is to discuss the principles of Finite Difference Method and its applications in groundwater modelling. To achieve this, a rectangular grid is overlain an aquifer in order to obtain an exact solution. Initial and boundary conditions are then determined. By discretizing the system into grids and cells that are small compared to the entire aquifer, exact solutions are obtained. A flow chart of the computational algorithm for particle tracking is also developed. Results show that under a steady-state flow with no recharge, pathlines coincide with streamlines. It is also found that the accuracy of the numerical solution by Finite Difference Method is largely dependent on initial particle distribution and number of particles assigned to a cell. It is therefore concluded that Finite Difference Method can be used to predict the future direction of flow and particle location within a simulation domain. 展开更多
关键词 Finite difference Method GROUNDWATER modelLING Particle Tracking Algorithm DISCRETIZATION Flow Rates HYDRAULIC HEADS
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Animal Models of Obsessive-Compulsive Disorder: Strain Differences
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作者 Taimon P. Maio Guilherme B. Filgueiras +1 位作者 Daniel C. Cunha Celio Estanislau 《World Journal of Neuroscience》 2014年第3期240-246,共7页
Obsessive-compulsive disorder (OCD) is characterized by obsessions (intrusive thoughts, images etc.) and compulsions (repetitive, stereotyped and perseverant acts). Animal models of OCD are specifically devoted to sim... Obsessive-compulsive disorder (OCD) is characterized by obsessions (intrusive thoughts, images etc.) and compulsions (repetitive, stereotyped and perseverant acts). Animal models of OCD are specifically devoted to simulating compulsive features of the disorder. In OCD, compulsive behaviors are recognized as repetitive and maladaptive and symptoms relief can be experienced due to treatment with selective serotonin reuptake inhibitors. Many animal models of OCD are provided with some degree of validity. Genetically based differences in behavior in animal models of OCD are of great value, given that human OCD is reported to involve genetic factors. Some animal models of OCD were already used in studies for the evaluation of strain differences. These works were explored in the present review. 展开更多
关键词 OBSESSIVE-COMPULSIVE DISORDER ANIMAL models Strain differenceS INDIVIdual differenceS
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