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Ancient and modern medication laws of aromatic Chinese medicines in treating angina pectoris based on data mining 被引量:1
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作者 WANG Chaoping LUO Jing +5 位作者 WAN Qiang CAO Meifang ZHA Qinglin LEI Zhiqiang Abid Naeem YANG Ming 《Digital Chinese Medicine》 2022年第2期123-140,共18页
Objective To explore ancient and modern medication laws of aromatic Chinese medicines in treating angina pectoris, and to provide new ideas for the clinical treatment.Methods With “angina pectoris” as the key word, ... Objective To explore ancient and modern medication laws of aromatic Chinese medicines in treating angina pectoris, and to provide new ideas for the clinical treatment.Methods With “angina pectoris” as the key word, ancient books prescriptions and Chinese patent medicines related to angina pectoris were collected from China National Knowledge Infrastructure(CNKI), Traditional Chinese Medicine Database System, Chinese Medicine Prescription Database, New National Proprietary Chinese Medicine(2 nd edition), and Chinese Pharmacopoeia(2020 edition) from January 1, 2015 to December 31, 2021. Core highfrequency aromatic Chinese medicines were defined, and their potential medication rules were analyzed and summarized. Microsoft Access 2010 was used for data management. Data analysis software, including Excel and IBM SPSS Modeler 18.0 were used for drug association rule analysis, and Cytoscape 3.7.2 for visual display.Results There were 67 ancient books prescriptions and 258 Chinese patent medicines containing aromatic Chinese medicines treating angina pectoris collected from relevant databases. In ancient books prescriptions, there were nine aromatic Chinese medicines with the frequency ≥10, and the most commonly used medicine was Danggui(Angelicae Sinensis Radix), followed by Chenpi(Citri Reticulatae Pericarpium). There were 33 aromatic Chinese medicines with the frequency ≥10 in Chinese patent medicines, and the most commonly used medicine was Danshen(Salviae Miltiorrhizae Radix et Rhizoma), followed by Chuanxiong(Chuanxiong Rhizoma) and Sanqi(Notoginseng Radix et Rhizoma). In ancient books prescriptions, the medicines mainly belonged to intenal-warming medicines, Qi-regulating medicines, and blood circulation promoting and blood stasis removing medicines.There were eight medicine pairs with confidence equal to 100% in ancient books prescriptions, the most frequently used pairs were Chuanxiong(Chuanxiong Rhizoma) +Danggui(Angelicae Sinensis Radix), and Xiangfu(Cyperi Rhizoma) + Chenpi(Citri Reticulatae Pericarpium). In Chinese patent medicines, the aromatic Chinese medicine Chuanxiong(Chuanxiong Rhizoma) could be combined with many other Chinese medicines, among which the Confidence and Support of Chuanxiong(Chuanxiong Rhizoma) + Danshen(Salviae Miltiorrhizae Radix et Rhizoma) were at a high level.Conclusion Aromatic Chinese medicines for the treatment of angina pectoris of coronary heart disease are mainly warm, and the flavors are mainly pungent, sweet, and bitter. They mainly access to the liver, gallbladder, and pericardium meridians. The treatment of angina pectoris of coronary heart disease mainly focuses on warming heart pulse, and promoting blood circulation and removing blood stasis. 展开更多
关键词 Aromatic Chinese medicines Ancient books prescriptions Chinese patent medicines Angina pectoris Medication laws Chuanxiong(Chuanxiong Rhizoma)
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Applicability of Zipfs Law in Traditional Chinese Medicine Prescriptions
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作者 Yuanbai Li Yu Du +5 位作者 Fangzhou Liu Yiying Zhang Meng Li Jing Wang Yihao Li Yang Yang 《Chinese Medical Sciences Journal》 CAS CSCD 2022年第3期195-200,I0004,共7页
Objective Traditional Chinese medicine(TCM)prescriptions have been used to cure diseases in China for thousands of years,in which many TCM herbs have no definite common quantity.Some key TCM herbs are commonly used an... Objective Traditional Chinese medicine(TCM)prescriptions have been used to cure diseases in China for thousands of years,in which many TCM herbs have no definite common quantity.Some key TCM herbs are commonly used and thus deserve in-depth investigations based on a more acceptable classification method.This study analyzes whether TCM prescriptions follow Zipf's law and attempts to obtain the thresholds of key TCM herbs based on the application of Zipfs law;Methods A total of 84,418 TCM prescriptions were collected and standardized.We tested whether Zipf's law and Zipfs distribution fit the Chinese herb distributions.A linear fitting experiment was performed to verify the relationship between the frequency distribution and frequency of TCM herbs.Results The distribution of TCM herbs in TCM prescriptions conformed to Zipf's law.Accordingly,the thresholds were obtained for the key TCM herbs.Conclusion The distribution of TCM herbs in TCM prescriptions follows Zipfs law. 展开更多
关键词 Zipf's law traditional Chinese medicine PRESCRIPTIONS HERB
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Traditional Chinese Medicine in Malaysia: A Brief Historical Overview of Laws and Regulations
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作者 Hon Foong Wong Shih Chau Ng +6 位作者 Wen Tien Tan Huiying Wang Xun Lin Si Woei Goh Bao Ling Hoo Chyong En Chai Jun Liu 《Chinese Medicine and Culture》 2019年第4期162-165,共4页
Although traditional Chinese medicine(TCM)has been a part of the Malaya and the Malaysia people’s method of maintaining health and well-being for many centuries,it was never been enrolled in the public health-care sy... Although traditional Chinese medicine(TCM)has been a part of the Malaya and the Malaysia people’s method of maintaining health and well-being for many centuries,it was never been enrolled in the public health-care system.However,the rising cost of Western drugs and the increasing number of people frequenting TCM has driven the government to search for cheaper options and to look into its safe practice.In 1992,the government mandated all TCM herbal products to be registered with the National Pharmaceutical Control Bureau.All TCM products sold in Malaysia are now Good Manufacturing Practice certified.The government has also established a Traditional and Complementary Medicine Division within the Ministry of Health.Between 2008 and 2014,a traditional and complementary medicine unit was set up in major hospitals in all states.TCM is one of the main services offered by the unit.In 2016,the government enacted the Traditional and Complementary Medicine Act to regulate the TCM practice.Subsequently,a 10-vear blueprint has been drawn to support the development of all traditional and complementary medicines in Malaysia.This article aims to provide a brief overview on the regulatory development of TCM in Malaysia. 展开更多
关键词 Development of traditional Chinese medicine historical overview laws and regulations MALAYSIA Traditional Chinese medicine
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Literature on the law of Miao medicine in treating liver cancer
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作者 Huili Shui Zhu Yang +4 位作者 Fengxi Long Wenqi Huang Bing Yang Zhen Zhang Dongxin Tang 《TMR Clinical Research》 2018年第1期25-40,共16页
Aims:Through the literature review of Miao medicine for liver cancer,this paper discussed the law of Miao medicine for liver cancer.Methods:Using"Zhonghua Bencao Miao medicine"as the source of literature,the... Aims:Through the literature review of Miao medicine for liver cancer,this paper discussed the law of Miao medicine for liver cancer.Methods:Using"Zhonghua Bencao Miao medicine"as the source of literature,the search term was prepared to search the related literature of CNKI database and Wanfang database for the treatment of liver cancer in the Miao medicine from May 2018.The qualified drugs were used to conduct statistical analysis on their family genus,medicinal property,medicinal taste,regression and efficacy.Results:A total of 132 flavors of Miao medicine for liver cancer were included,and the high-frequency family was compositae,liliaceae,and rosaceae,accounting for 22.8%.The medicine was mainly cold medicine,accounting for 75.8%.The main taste of medicine was bitter,hot and sweet,accounting for 75.5%.The main parts of longitude are hot longitude and cold longitude,accounting for 90.5%.Drugs are mainly used to cure poison,tonifying body and vent the blood,a total of 80.4%.Conclusions:Miao medical treatment of liver cancer is based on the dialectic of cold and heat,with proper use of tonifying body and vent the blood drugs. 展开更多
关键词 Miao medicine Liver cancer medicine law Literature research
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Analysis of medication law of treatment of cholelithiasis by internal traditional Chinese medicine based on traditional Chinese medicine inheritance system
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作者 Xu-Yan Wang Yi-Hua Fan +4 位作者 Chen Yang Hui-Wen Bai Si-Yu Ai Hao-Lin Liu Xin-Ju Li 《History & Philosophy of Medicine》 2020年第4期129-144,共16页
Objective:Based on the Traditional Chinese Medicine Inheritance System version 2.5 to explore the rule of medication used in internal traditional Chinese medicine for cholelithiasis in the national patent network.Meth... Objective:Based on the Traditional Chinese Medicine Inheritance System version 2.5 to explore the rule of medication used in internal traditional Chinese medicine for cholelithiasis in the national patent network.Method:Collect the internal administrations of cholelithiasis in the national patent network,and enter them into the Chinese medicine inheritance system version 2.5,adopt frequency analysis,association rules,complex system entropy clustering and other data mining methods to analyze the prescription rule of traditional Chinese medicine cholelithiasis.Results:According to the inclusion and exclusion criteria,215 prescriptions were selected,involving 398 drugs,30 drugs with a frequency of>20,and 39 commonly used drug pairs.The core drugs are:Jinqiancao(Herba Lysimachiae),Yujin(Radix Curcumae),Chaihu(Radix Bupleuri),Yinchen(Herba Artemisiae Scopariae),Jineijin(Endothelium Corneum Gigeriae Galli),Dahuang(Radix et Rhizoma Rhei),Gancao(Radix Glycyrrhizae),Huangqin(Radix Scutellariae),Baishao(Raidix Paeoniae Alba),Muxiang(Radix Aucklandiae),Zhishi(Fructus Aurantii Immaturus),Yanhusuo(Rhizoma Corydalis),Huzhang(Rhizoma Polygoni Cuspidati),Haijinsha(Herba Lygodii).And 9 new prescriptions have been got.Conclusion:In the national patent network,the traditional Chinese medicine is used in the treatment of cholelithiasis.The main treatment is clearing heat and dampness,regulating Qi and relieving pain,and promoting gallbladder removing stone,providing reference for clinical treatment of cholelithiasis. 展开更多
关键词 CHOLELITHIASIS Traditional Chinese medicine Medication law Traditional Chinese medicine inheritance system
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The law of oral traditional Chinese medicine for insomnia based on Chinese medical code
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作者 Yuyan Li Yihua Fan +3 位作者 Jinxiang Mao Naijin Zhang Aikedai·Abulimiti Kai Zhong 《Medical Data Mining》 2019年第4期160-168,共9页
Objective:This study aimed to collect,sort out and excavate the literature on the diagnosis and treatment of insomnia in Chinese Medical Code,and to explore the law of internal administration of traditional Chinese me... Objective:This study aimed to collect,sort out and excavate the literature on the diagnosis and treatment of insomnia in Chinese Medical Code,and to explore the law of internal administration of traditional Chinese medicine in the treatment of insomnia.Methods:We used"Chinese Medical Code"as the source of data retrieval,"insomnia","not sleepy","no sleeping"and"eye not sleeping"as the key words,and excluded temporary insomnia,physiological insomnia,insomnia caused by other diseases,and excluded other methods such as acupuncture and massage,the medical cases.Prescriptions of insomnia treated with traditional Chinese medicine were screened out.The database was established by using Microsoft excel 2010.Descriptive statistics were used to analyze the frequency,menstruation of nature,taste and efficacy of traditional Chinese medicine.We analyzed the association rules between drugs and mined the rules of prescriptions by the Apriori algorithm in SPSS Modeler 14.1.Results:A total of 147 prescriptions,138 traditional Chinese medicines,20 pairs of core drugs,57 common drug combinations and 3 core pharmaceuticals were included.The basic prescription is:Suan Zao Ren,Bai Zi Ren,Fu Shen,Fu Ling,Yuan Zhi,Dang Gui,Gan Cao(Zhi).Conclusion:In summary,according to the drug analysis above,the main disease of insomnia is in the heart,involving the liver,spleen and kidney.Because it involves different viscera and syndrome,the methods of treatment are also different.However,there is a basic pathogenesis,that’s the loss of mental nourishment.By excavating the law of the use of traditional Chinese medicine in the treatment of insomnia on the Chinese Medical Code,we expect that it can guide the treatment of insomnia. 展开更多
关键词 INSOMNIA literature mining medicine law Chinese Medical Code
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A study on the medication law of oral administration of traditional Chinese medicine in treating breast carbuncle based on the Traditional Chinese Medicine Prescription Dictionary
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作者 Jun Chang Yi-Hua Fan +2 位作者 Jiang-Jiang Fu Hao-Lin Liu Ming-Xing Zhang 《History & Philosophy of Medicine》 2021年第2期3-13,共11页
Objective:Based on the database of Traditional Chinese Medicine Prescription Dictionary,the prescription medication rules of oral administration of traditional Chinese medicine in the treatment of breast carbuncle wer... Objective:Based on the database of Traditional Chinese Medicine Prescription Dictionary,the prescription medication rules of oral administration of traditional Chinese medicine in the treatment of breast carbuncle were explored by using the software of Traditional Chinese Medicine Inheritance Support System(V2.5).Methods:To screen and retrieve the prescriptions for treating breast carbuncle in the Traditional Chinese Medicine Prescription Dictionary,and data mining was carried out by using association rule algorithm,complex system entropy clustering and so on.Results:A total of 208 prescriptions which met the inclusion criteria were selected,involving 175 traditional Chinese medicines.Among them,23 medicines were found to be more than 21 times in the treatment of breast carbuncle.The nature of the medicine is mainly cold or warm,the flavour of the medicine is mainly bitter or sweet,most of them belong to the spleen,liver,stomach.15 commonly used drug combinations and 9 new prescriptions were obtained.Conclusion:The key pathogenesis of breast carbuncle is liver depression and Qi stagnation,stomach heat blocking collaterals,the treatment is mainly to clear heat and detoxify,regulate Qi to diffuse the knot,which provides reference for the choose of traditional Chinese medicine prescription in treating breast carbuncle. 展开更多
关键词 Traditional Chinese medicine Prescription Dictionary Breast carbuncle Traditional Chinese medicine Inheritance Support System Medication law
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Based on the Chinese medical canon to excavate the medicine law of yellowish leucorrhea disease
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作者 Xu-Yan Wang Yi-Hua Fan +4 位作者 Yu-Yan Li Zhao Jiao Xin-Ju Li Hua Jin Jie Guo 《Medical Data Mining》 2020年第4期141-151,共11页
Background:In order to collect and analyze the literature on yellowish leucorrhea disease in Chinese Medical Canon,and to explore its treatment and medication law with data mining.Methods:The Chinese Medical Canon was... Background:In order to collect and analyze the literature on yellowish leucorrhea disease in Chinese Medical Canon,and to explore its treatment and medication law with data mining.Methods:The Chinese Medical Canon was used as the data retrieval source,and“Huangdai”(yellowish leucorrhea disease)and and other keywords were used as the keywords to do literature search.After excluding“gestational yellowish leucorrhea”,“jaundice and yellowish leucorrhea”and other diseases,the literature retrieval and data sorting and analysis were carried out,and the database was established by using Microsoft Excel 2010.Descriptive statistical method was used to analyze the nature,flavour,channel tropism and efficacy of medicine.Combined with the method in“the Research Platform for Inheritance of Traditional Chinese Medicine Academic Thoughts of Famous Gynecologists of Traditional Chinese Medicine”,the association rules between drugs were analyzed and their rules were excavated.Results:Eighty-seven prescriptions,152 traditional Chinese medicines,20 core drug pairs,39 common drug combinations and 5 core drug groups were collected and included.Conclusion:“Damp-Heat”is the fundamental pathological product of yellowish leucorrhea disease,and the basic treatments are“Releasing Heat”and“Eliminating Dampness”,“Regulating Liver Qi”and“Promoting Blood Circulation”,and“strengthening spleen”and stopping leucorrhea. 展开更多
关键词 Literature mining Yellowish leucorrhea disease medicine law Chinese Medical Canon
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Analysis on the Law of Chinese Medicine Use of Ulcerative Colitis and TCM Syndrome Differentiation and Treatment
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作者 Jiaojiao Zhang Heng Mu +3 位作者 Xiaogang Wang Xingxing Yu Fan Zhang Yi Li 《Proceedings of Anticancer Research》 2021年第3期24-26,共3页
Ulcerative colitis is a kind of inflammatory bowel disease.The disease is slow and easy to relapse.Western medicine treatment mainly focuses on symptomatic treatment,which has certain side effects on liver and kidney ... Ulcerative colitis is a kind of inflammatory bowel disease.The disease is slow and easy to relapse.Western medicine treatment mainly focuses on symptomatic treatment,which has certain side effects on liver and kidney function.Ulcerative colitis has unique advantages in disease,so by studying a large amount of information,mainly from the law of traditional Chinese medicine use of UC,and a brief summary of the treatment of TCM syndromes,this article provide s ideas and basis for clinical diagnosis and treatment of the disease. 展开更多
关键词 Ulcerative colitis law of traditional Chinese medicine Syndrome differentiation and treatment
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Medication rules of traditional Chinese medicine ointment for diabetic foot ulcer 被引量:1
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作者 Ren-Yan Huang Hui-Jing Fan Guo-Bin Liu 《Journal of Hainan Medical University》 2021年第4期58-63,共6页
Objective:Based on data mining,to explore the clinical characteristics of traditional Chinese medicine ointment in the treatment of diabetic foot ulcer.Methods:to search the literatures about the treatment of diabetic... Objective:Based on data mining,to explore the clinical characteristics of traditional Chinese medicine ointment in the treatment of diabetic foot ulcer.Methods:to search the literatures about the treatment of diabetic foot ulcer by traditional Chinese medicine ointment in CNKI,Wangfang and VIP.In this paper,the prescription of traditional Chinese medicine ointment in the literature of treating diabetic foot ulcer was extracted,and the database of prescription was established by using v2.5 to analyze and mine the rule of medication.Results:95 prescriptions for diabetic foot ulcer were sorted out,involving 158 prescriptions.Among them,dragon's blood and Lithospermum are the most frequently used drug combinations.The core combination of 10 groups and 5 new prescriptions are obtained by evolution.Conclusion:the treatment of diabetic foot ulcer with traditional Chinese medicine ointment mainly includes clearing away heat,promoting blood circulation and removing blood stasis,and tonifying deficiency. 展开更多
关键词 Chinese medicine ointment Diabetic foot ulcer Medication law
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Traditional Chinese Medicine:How Is It An Invaluable Intangible Cultural Heritage 被引量:1
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作者 Anwen Zheng 《Chinese Medicine and Culture》 2019年第2期84-87,共4页
This article deals with the concept of intangible culture heritage and the reasons why traditional Chinese medicine(TCM)should be specially preserved.The potential value of TCM and the existing measures for carrying o... This article deals with the concept of intangible culture heritage and the reasons why traditional Chinese medicine(TCM)should be specially preserved.The potential value of TCM and the existing measures for carrying on the cultural heritage adopted by China are also explored in the article. 展开更多
关键词 Intangible culture heritage traditional Chinese medicine VALUE laws and regulations
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Informed consent in veterinary medicine: legal and medical perspectives in Italy
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作者 Annamaria Passantino Valeria Quartarone Maria Russo 《Open Journal of Animal Sciences》 2011年第3期128-134,共7页
During the last four decades the doctrine of in- formed consent (IC) has become a legal stan- dard and an essential component of ethical guidelines in medicine, due to its relevance for basic human rights such as auto... During the last four decades the doctrine of in- formed consent (IC) has become a legal stan- dard and an essential component of ethical guidelines in medicine, due to its relevance for basic human rights such as autonomy and re- spect of dignity. Over the last few years, this legal formula has gained importance in veteri- nary medicine, thereby influencing the everyday activities of the veterinary practitioners. This paper briefly describes the ethical and legal background of IC in Italy and examines how it relates to the practice of veterinary medicine, considering the change in social sensibility to- wards animals. It also outlines the discussion that should take place between Veterinarian and client before a planned procedure. 展开更多
关键词 INFORMED Consent VETERINARY medicine Professional DUTY law ETHICS Veterinarian-Client Relationship Animal
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The World’s under Five Population—Do We Really Have Good Data of Its Size in Medicine?
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作者 Gregor Pollach 《International Journal of Clinical Medicine》 2014年第10期599-604,共6页
Background: “Forensic auditing” opened a new way to monitor demographic data. Benford’s law explains the frequency distribution in naturally occurring data sets. We applied this law to data of the world’s populati... Background: “Forensic auditing” opened a new way to monitor demographic data. Benford’s law explains the frequency distribution in naturally occurring data sets. We applied this law to data of the world’s population under five. This number is extremely important in paediatrics and public health. Methodology: Benford’s law states that the probability of a leading occurring number d (d ∈ {1,···,9}) can be calculated through the following equation: P(d) = log10(d + 1) – log10(d) = log10(1 + 1/d). We compared the observed and expected values. To examine statistical significance, we used the Chi-square test. Results: Chi-square for the population younger than five years is 22.74 for 2010, 22.97 for 2011 and 11.35 for 2012. For all years combined it is 47.6. Because chi-square was higher than the cut-off value, it must lead to the rejection the null hypothesis. In 2014 chi-square is 11.73 for the first digit. Chi-square being lower than the cut off value of the null hypothesis is accepted. The acceptance of the null hypothesis for 2014 means that the numbers follow Benford’s law for 2014. The rejection of the null hypothesis means that the numbers observed in the publication are not following Benford’s law. The explanations can be reached from operational discrepancies to psychological challenges or conscious manipulation in the struggle for international funding. Conclusion: The knowledge of this mathematical relation is not used widely in medicine, despite being a valuable and quick tool to identify datasets needing closer scrutiny. 展开更多
关键词 Benford’s law Forensic Auditing Under FIVE STRUGGLE for FUNDING FRAUD First-Digit law A New Tool in medicine
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Analysis of effect of external therapies of traditional Chinese medicine on eczema by data mining
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作者 Xin-Rui Qiu Xiao-Ning Yan +1 位作者 Lu Chen Wen-Bin Li 《Journal of Hainan Medical University》 2021年第1期49-53,共5页
Objective:To determine medication regularity external therapies of Traditional Chinese medicine of eczema by data mining.Methods:Papers were retrieved from databases Pubmed,CNKI,WF,VIP,CBM,Web of Science and Embase.Fr... Objective:To determine medication regularity external therapies of Traditional Chinese medicine of eczema by data mining.Methods:Papers were retrieved from databases Pubmed,CNKI,WF,VIP,CBM,Web of Science and Embase.From the establishment of the database to April 2020 were searched.The main points of Medication Regularity were established with Excel 2016 software;the characteristics and laws in external therapies of Traditional Chinese medicine Treatment of eczema were analyzed with the relevance rule and cluster analysis Methods in data mining technology.Results:The property and flavor of the herbs mainly used were cold,bitter,while the channel which are mostly involved included liver meridian,lung meridian and Bladder Meridian,The analysis of association rules showed that kushen and difuzi had the highest correlation.The clustering analysis figured out 7groups of the herbs.Conclusion:The study presents the common pair herbs in the treatment of external therapies of Traditional Chinese medicine of eczema,which provides the approach to syndrome differentiation and medication in clinical treatment of eczema. 展开更多
关键词 ECZEMA External therapies of Traditional Chinese medicine Medication law DATA-MINING
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Pharmaceutical Rules of Traditional Chinese Medicine For Stroke Based on Dictionary of Prescriptions and Complex Network Analysis
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作者 Xiu-Lei Jiang Yi-Di Wang +4 位作者 Zun-Hao Tang Jing-Chao Sun Meng-Yuan Cai Yu-Chen Liu Yu-Qiu Li 《Medical Data Mining》 2018年第2期83-92,共10页
Objective:Taking the Dictionary of Prescriptions as a clue,we collected effective prescriptions for treating Stroke,and systematically summarized the medication and compatibility rules of the core Chinese medicines fo... Objective:Taking the Dictionary of Prescriptions as a clue,we collected effective prescriptions for treating Stroke,and systematically summarized the medication and compatibility rules of the core Chinese medicines for treating Stroke.Methods:A database of prescriptions for stroke based on complex relationship analysis system of traditional Chinese medicine was established.From the point of view of complex network,the hierarchy of drug compatibility rules of compound prescriptions(such as courtiers and envoys)was analyzed,the statistical characteristics of complex networks were analyzed,and an attempt was made to explain the characteristics of complex networks of drugs for stroke.Results:A total of 974 prescriptions were collected,including 1040 Chinese herbs.The core Chinese herbal medicines with nodal degree(>500)for Stroke were divaricate saposhnikovia root,liquorice root,Chinese angelica,tall gastrodia tuber,incised notopterygium rhizome and root.The compatibility relationship of the core Chinese medicines in the treatment of stroke is divaricate saposhnikovia root-liquorice root,ephedra-divaricate saposhnikovia root,divaricate saposhnikovia root-sichuan lovage rhizome,divaricate saposhnikovia root-Chinese angelica in order of frequency.Conclusion:Through the analysis of the common network structure of effective prescriptions for Stroke,the core prescription compatibility structure reflecting the prescription thinking and clinical characteristics was found. 展开更多
关键词 STROKE TCM Complex network relationship Formula DICTIONARY of Traditional Chinese medicine Compatibility law
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Subjectivities of the Scientific Endeavor:Noting the Illusion of Objectivity in the History of Science and Medicine
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作者 Imanni K.Sheppard 《History & Philosophy of Medicine》 2022年第1期4-8,共5页
The history of science and medicine has long been steeped in the notion that they are objective(untainted by the philosophical and ideological ebbs and flows of society)and utilitarian(doing what is best for the great... The history of science and medicine has long been steeped in the notion that they are objective(untainted by the philosophical and ideological ebbs and flows of society)and utilitarian(doing what is best for the greater good).Because of this,scientific and medical epistemologies and praxis are often held to an esteem that is unquestioned,celebrated,and occasionally unchecked.A closer look at the history of science and medicine,however,readily reveal the extent to which the milieu of society has informed scientific and medical endeavors.As such,an understanding of how the subjectivities of scientific and medical endeavors situate within our contemporary disciplines and practices is significant to one’s ability to truly understand said disciplines.Likewise,such an evaluation will provide insight into our role in perpetuating the illusion of objectivity in these fields.With this in mind,this paper provides a philosophical and historical examination of the concept of objectivity(in contrast to subjectivity)in science and medicine. 展开更多
关键词 OBJECTIVITY SUBJECTIVITY history of science history of medicine natural law
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Empirical study on the evidence-based medicine in court of China
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作者 Xin Xing Si-Da Shen 《History & Philosophy of Medicine》 2022年第1期11-15,共5页
Evidence-based medicine(EBM)is recognized as one of the highest-quality scientific approaches in the medical community around the globe.It calls for doctors to use the best available scientific evidence in clinical de... Evidence-based medicine(EBM)is recognized as one of the highest-quality scientific approaches in the medical community around the globe.It calls for doctors to use the best available scientific evidence in clinical decision-making.This paper used an empirical study on 44 EBM related judicial cases in China,the result shows the EBM is commonly used as a supplement to the expert opinion in actual judicial review,it is deemed to illuminate the causation in the case fact rather than as the standards of care,which has the similar characteristics as"documentary evidence",and over the years the Chinese judicial practice formed a"three-stage"judicial review rule on EBM:(1)the first stage is whether the evidence itself can meet the standards of EBM;(2)the second stage is when determining the evidence presented by parties is sufficient to meet the legal standards of EBM,and whether it can be applied in a court case would depend upon comprehensive consideration of adaptability and maturity of EBM;(3)the third stage is whether to treat EBM as the only basis in causation analysis. 展开更多
关键词 evidence-based medicine judicial review court decision Chinese law
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基于数据挖掘和网络药理学探讨中药治疗慢性萎缩性胃炎伴肠上皮化生的用药规律及机制研究
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作者 李萌 田志华 +3 位作者 陈丁铭 陈敬予 王少丽 刘震 《中国医院用药评价与分析》 2024年第7期783-788,共6页
目的:探讨中药干预慢性萎缩性胃炎伴肠上皮化生的用药规律,分析常用药对的潜在作用机制。方法:检索中国知网、万方数据库和维普数据库中收录的文献(建库至2022年6月30日),利用Excel、SPSS Modeler 18.1和SPSS Statistics 26软件对纳入... 目的:探讨中药干预慢性萎缩性胃炎伴肠上皮化生的用药规律,分析常用药对的潜在作用机制。方法:检索中国知网、万方数据库和维普数据库中收录的文献(建库至2022年6月30日),利用Excel、SPSS Modeler 18.1和SPSS Statistics 26软件对纳入的中药进行频次统计、关联规则分析和聚类分析,再利用中药系统药理学数据库与分析平台、GeneCards、STRING和Cytoscape等工具进行蛋白质-蛋白质相互作用、京都基因与基因组百科全书通路富集分析,揭示潜在作用机制。结果:共筛选出处方100个,中药187味,药性以温、平、寒为主,药味以苦、甘为主,归经多为脾、胃经。使用频次≥20次的中药21味,白术-白花蛇舌草为支持度最高的药物组合。白术-白花蛇舌草药对治疗慢性萎缩性胃炎伴肠上皮化生的核心成分为槲皮素、β-谷甾醇和豆甾醇,核心靶点为肿瘤蛋白p53、蛋白激酶B1和转录因子AP-1等,主要作用通路为肿瘤相关通路、乙型肝炎病毒和晚期糖基化终末产物(AGE)-AGE受体信号通路等。分子对接结果显示,3个关键成分与3个核心靶点具有较好的结合活性。结论:中药治疗慢性萎缩性胃炎伴肠上皮化生以健脾理气、清热活血为主,白术-白花蛇舌草从多成分、多靶点、多通路对慢性萎缩性胃炎合并肠上皮化生发挥治疗作用,为进一步进行机制研究奠定了理论基础。 展开更多
关键词 中药 慢性萎缩性胃炎 肠上皮化生 用药规律 作用机制
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专利中药处方治疗放射性肺损伤的用药规律及作用机制研究
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作者 李梅 李建华 +4 位作者 刘欢 王志鹏 高洁 袁慧 孙鸽 《癌变.畸变.突变》 CAS 2024年第4期275-280,共6页
目的:搜集国家专利中治疗放射性肺损伤的中药处方,探索其用药规律及作用机制。方法:检索国家知识产权局中国专利公布网站中治疗放射性肺损伤的中药处方,利用古今医案云平台进行统计分析、关联分析、聚类分析及网络构建分析等;通过网络... 目的:搜集国家专利中治疗放射性肺损伤的中药处方,探索其用药规律及作用机制。方法:检索国家知识产权局中国专利公布网站中治疗放射性肺损伤的中药处方,利用古今医案云平台进行统计分析、关联分析、聚类分析及网络构建分析等;通过网络药理学方法探讨治疗放射性肺损伤核心处方的作用靶点及相关通路。结果:纳入从专利数据库建立至2022年8月治疗放射性肺损伤的中药处方专利17项,共包含153味中药,药物出现频次较高的有甘草、生地黄;常用的药对为玄参-生地黄、苦杏仁-甘草、鱼腥草-甘草、生地黄-玄参;核心处方组成包括甘草、生地黄、苦杏仁、玄参和鱼腥草;核心处方治疗放射性肺损伤的主要靶点可能为JUN、IL-6、PTGS2、FOS、IL-8、IL-10等,相关的作用通路有脂质与动脉粥样硬化、化学致癌-受体激活、化学致癌-活性氧物种、PI3K-Akt信号通路、MAPK信号通路等。结论:专利中药处方主要可能通过抑制炎症反应从而发挥减轻放射性引起的肺损伤作用。 展开更多
关键词 放射性肺损伤 专利中药处方 用药规律 网络药理学
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中华优秀传统法律文化的创造性转化和创新性发展 被引量:1
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作者 李林 《国家现代化建设研究》 2024年第1期28-41,共14页
中华优秀传统法律文化具有普遍性和共同性、先进性和文明性、实践性和人民性,符合人类法治文明发展的普遍规律、共同价值和科学理性。推动中华优秀传统法律文化的创造性转化和创新性发展,应当高度重视并大力加强对有关国家和地区对中华... 中华优秀传统法律文化具有普遍性和共同性、先进性和文明性、实践性和人民性,符合人类法治文明发展的普遍规律、共同价值和科学理性。推动中华优秀传统法律文化的创造性转化和创新性发展,应当高度重视并大力加强对有关国家和地区对中华法系以及域外法律文化转化融合经验的比较研究,走出一条“借鉴”与“双创”相结合的中国自主法学知识体系构建之路;应当坚持把马克思主义法治基本原理同中国法治实践相结合、同中华优秀传统法律文化相结合,推进“中医法学”与“西医法学”有机融合,开创中国式现代化法治文明新境界。 展开更多
关键词 中华优秀传统法律文化 法治文明 中华法系 “中医法学” “西医法学”
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