【目的】探讨人工肝血浆置换技术治疗重症肝炎患者的临床效果和常见不良反应。【方法】本院180例重症肝炎患者按照随机原则分为治疗组和对照组，每组90例。对照组90例采取护肝降酶及防治并发症等内科综合疗法，治疗组在对照组基础上，...【目的】探讨人工肝血浆置换技术治疗重症肝炎患者的临床效果和常见不良反应。【方法】本院180例重症肝炎患者按照随机原则分为治疗组和对照组，每组90例。对照组90例采取护肝降酶及防治并发症等内科综合疗法，治疗组在对照组基础上，联合人工肝血浆置换术治疗，比较两组患者治疗前后的血液生化指标变化及常见不良反应，同时观察治疗组中急性重型肝炎、亚急性重型肝炎、慢加急性重型肝炎、慢性重型肝炎的治疗效果差异。【结果】治疗组总有效率为81．11％，对照组总有效率为52．22％，二者比较差异有显著性（ P ＜0．01），治疗组经人工肝血浆置换术治疗后谷丙转氨酶（ALT ）、谷草转氨酶（AST ）、总胆红素（TBIL）、白蛋白（ALB）；凝血酶原活动（PTA）；胆碱酯酶（ChE）与对照组比较差异有显著性（ P ＜0．01）。治疗组中各型肝炎治疗有效率从高到低依次为亚急性重型肝炎有效率96．29％，慢加急性重型肝炎91．17％，慢性重型肝炎66．66％，急性重型肝炎35．71％，各类患者疗效差异明显。治疗组患者不良反应有皮肤瘙痒和皮疹、四肢痉挛、鼻腔出血、肢体麻木等，经对症处理后均好转。【结论】人工肝血浆置换术是重型肝炎患者安全有效的治疗选择，尤其对亚急性重型肝炎疗效更佳。展开更多
In this study,servo-controlled biaxial compression tests were conducted on marble specimens to investigate their failure characteristics and fracturing process.The complete stressestrain curves were obtained,and the t...In this study,servo-controlled biaxial compression tests were conducted on marble specimens to investigate their failure characteristics and fracturing process.The complete stressestrain curves were obtained,and the three-dimensional(3D)features of the failure surfaces were acquired by 3D laser scanning.Acoustic emission(AE)monitoring and moment tensor(MT)analysis were used in combination to better understand the fracturing mechanism of marble under biaxial compression.It was noted that a type of 3D stepwise cracking behaviour occurred on the fracturing surfaces of the examined specimens.The stress dropped multiple times,and a repeated fracturing mode corresponding to the repeated stress drops in the post-peak regime was observed.Three substages,i.e.stress stabilisation,stress decrease and stress increase,were identified for a single fracturing mode.Then quantitative and statistical analyses of the fracturing process at each substage were discussed.Based on the testing results,it was found that at the stress stabilisation substage,the proportion of mixed-mode fractures increased.At the stress decrease substage,the proportion of mixed-mode fractures decreased,and the tensile or shear fractures increased.At the stress increase substage,the proportion of mixed-mode or tensile fractures decreased,and the shear fractures increased.Finally,a conceptual model for the stepwise crack formation was proposed.展开更多
This research aims to study various Symmetrical Algorithms, while the main objective of this study is to find out a suitable algorithm for the encryption of any specific size of text file where the experiment of each ...This research aims to study various Symmetrical Algorithms, while the main objective of this study is to find out a suitable algorithm for the encryption of any specific size of text file where the experiment of each algorithm is based on encryption of different sizes of the text files, which are in “10 KB to 5 MB”, and also to calculate the time duration that each algorithm takes to encrypt or to decrypt the particular size of each text file. There are many types of encryption algorithm, which can be used to encrypt the computerized information in different Organizations, whose all algorithms can encrypt and decrypt any size of text file, but the time duration of each Algorithm during the encryption or decryption process of specific file size is not fixed. Some of the algorithms are suitable for encryption of specific ranges of the file size, or some of algorithms are functional while encryption small size of files, and others algorithms are functional for encryption of big size of text files, based on the time duration disparity among symmetric algorithms during encryption of text files. In this study five symmetrical algorithms are merged in one program using classes and concept of inheritance in the form that if encryption is needed, the program will select the file and it checks the size of the text file. After this process the program automatically will select the suitable encryption algorithm to encrypt the specific text file according to the range of the file size. Knowing that the file size before or after encryption will not change or is stable, in this case of the decryption algorithm will apply the same process of encryption while decrypting files, the program of encryption and decryption code will write using visual Studio 2013. The result will be analyzed with R program (R software), the cipher text will appear in the format of UTF8 which means Unicode Transformation Format, “8” Means “8” bits to represent a character, the size format that will apply in the program will be in format of KB (kilo Byte).展开更多
We investigate the accuracy and robustness of moment tensor(MT)and stress inversion solutions derived from acoustic emissions(AEs)during the laboratory fracturing of prismatic Barre granite specimens.Pre-cut flaws in ...We investigate the accuracy and robustness of moment tensor(MT)and stress inversion solutions derived from acoustic emissions(AEs)during the laboratory fracturing of prismatic Barre granite specimens.Pre-cut flaws in the specimens introduce a complex stress field,resulting in a spatial and temporal variation of focal mechanisms.Specifically,we consider two experimental setups:(1)where the rock is loaded in compression to generate primarily shear-type fractures and(2)where the material is loaded in indirect tension to generate predominantly tensile-type fractures.In each test,we first decompose AE moment tensors into double-couple(DC)and non-DC terms and then derive unambiguous normal and slip vectors using k-means clustering and an unstructured damped stress inversion algorithm.We explore temporal and spatial distributions of DC and non-DC events at different loading levels.The majority of the DC and the tensile non-DC events cluster around the pre-cut flaws,where macro-cracks later develop.Results of stress inversion are verified against the stress field from finite element(FE)modeling.A good agreement is found between the experimentally derived and numerically simulated stress orientations.To the best of the authors’knowledge,this work presents the first case where stress inversion methodologies are validated by numerical simulations at laboratory scale and under highly heterogeneous stress distributions.展开更多
文摘【目的】探讨人工肝血浆置换技术治疗重症肝炎患者的临床效果和常见不良反应。【方法】本院180例重症肝炎患者按照随机原则分为治疗组和对照组，每组90例。对照组90例采取护肝降酶及防治并发症等内科综合疗法，治疗组在对照组基础上，联合人工肝血浆置换术治疗，比较两组患者治疗前后的血液生化指标变化及常见不良反应，同时观察治疗组中急性重型肝炎、亚急性重型肝炎、慢加急性重型肝炎、慢性重型肝炎的治疗效果差异。【结果】治疗组总有效率为81．11％，对照组总有效率为52．22％，二者比较差异有显著性（ P ＜0．01），治疗组经人工肝血浆置换术治疗后谷丙转氨酶（ALT ）、谷草转氨酶（AST ）、总胆红素（TBIL）、白蛋白（ALB）；凝血酶原活动（PTA）；胆碱酯酶（ChE）与对照组比较差异有显著性（ P ＜0．01）。治疗组中各型肝炎治疗有效率从高到低依次为亚急性重型肝炎有效率96．29％，慢加急性重型肝炎91．17％，慢性重型肝炎66．66％，急性重型肝炎35．71％，各类患者疗效差异明显。治疗组患者不良反应有皮肤瘙痒和皮疹、四肢痉挛、鼻腔出血、肢体麻木等，经对症处理后均好转。【结论】人工肝血浆置换术是重型肝炎患者安全有效的治疗选择，尤其对亚急性重型肝炎疗效更佳。
基金financial support received from the Key Research Program of Frontier Sciences,Chinese Academy of Sciences(CAS)(Grant No.QYZDJ-SSW-DQC016)。
文摘In this study,servo-controlled biaxial compression tests were conducted on marble specimens to investigate their failure characteristics and fracturing process.The complete stressestrain curves were obtained,and the three-dimensional(3D)features of the failure surfaces were acquired by 3D laser scanning.Acoustic emission(AE)monitoring and moment tensor(MT)analysis were used in combination to better understand the fracturing mechanism of marble under biaxial compression.It was noted that a type of 3D stepwise cracking behaviour occurred on the fracturing surfaces of the examined specimens.The stress dropped multiple times,and a repeated fracturing mode corresponding to the repeated stress drops in the post-peak regime was observed.Three substages,i.e.stress stabilisation,stress decrease and stress increase,were identified for a single fracturing mode.Then quantitative and statistical analyses of the fracturing process at each substage were discussed.Based on the testing results,it was found that at the stress stabilisation substage,the proportion of mixed-mode fractures increased.At the stress decrease substage,the proportion of mixed-mode fractures decreased,and the tensile or shear fractures increased.At the stress increase substage,the proportion of mixed-mode or tensile fractures decreased,and the shear fractures increased.Finally,a conceptual model for the stepwise crack formation was proposed.
文摘This research aims to study various Symmetrical Algorithms, while the main objective of this study is to find out a suitable algorithm for the encryption of any specific size of text file where the experiment of each algorithm is based on encryption of different sizes of the text files, which are in “10 KB to 5 MB”, and also to calculate the time duration that each algorithm takes to encrypt or to decrypt the particular size of each text file. There are many types of encryption algorithm, which can be used to encrypt the computerized information in different Organizations, whose all algorithms can encrypt and decrypt any size of text file, but the time duration of each Algorithm during the encryption or decryption process of specific file size is not fixed. Some of the algorithms are suitable for encryption of specific ranges of the file size, or some of algorithms are functional while encryption small size of files, and others algorithms are functional for encryption of big size of text files, based on the time duration disparity among symmetric algorithms during encryption of text files. In this study five symmetrical algorithms are merged in one program using classes and concept of inheritance in the form that if encryption is needed, the program will select the file and it checks the size of the text file. After this process the program automatically will select the suitable encryption algorithm to encrypt the specific text file according to the range of the file size. Knowing that the file size before or after encryption will not change or is stable, in this case of the decryption algorithm will apply the same process of encryption while decrypting files, the program of encryption and decryption code will write using visual Studio 2013. The result will be analyzed with R program (R software), the cipher text will appear in the format of UTF8 which means Unicode Transformation Format, “8” Means “8” bits to represent a character, the size format that will apply in the program will be in format of KB (kilo Byte).
文摘We investigate the accuracy and robustness of moment tensor(MT)and stress inversion solutions derived from acoustic emissions(AEs)during the laboratory fracturing of prismatic Barre granite specimens.Pre-cut flaws in the specimens introduce a complex stress field,resulting in a spatial and temporal variation of focal mechanisms.Specifically,we consider two experimental setups:(1)where the rock is loaded in compression to generate primarily shear-type fractures and(2)where the material is loaded in indirect tension to generate predominantly tensile-type fractures.In each test,we first decompose AE moment tensors into double-couple(DC)and non-DC terms and then derive unambiguous normal and slip vectors using k-means clustering and an unstructured damped stress inversion algorithm.We explore temporal and spatial distributions of DC and non-DC events at different loading levels.The majority of the DC and the tensile non-DC events cluster around the pre-cut flaws,where macro-cracks later develop.Results of stress inversion are verified against the stress field from finite element(FE)modeling.A good agreement is found between the experimentally derived and numerically simulated stress orientations.To the best of the authors’knowledge,this work presents the first case where stress inversion methodologies are validated by numerical simulations at laboratory scale and under highly heterogeneous stress distributions.
