Edible plant derived exosome-like nanoparticles(ELNs)have been shown to have multiple nutraceutical functions.However,the diversity of plant materials makes the plant derived ELN study challenging.More efforts are sti...Edible plant derived exosome-like nanoparticles(ELNs)have been shown to have multiple nutraceutical functions.However,the diversity of plant materials makes the plant derived ELN study challenging.More efforts are still needed to explore the feasible isolation methods of edible plant derived ELNs and the possible roles of food-derived ELNs in improving human health.In this study,a size exclusion chromatography based method was compared with the traditional ultracentrifugation method to isolate blueberry derived ELNs(B-ELNs),and the miRNA profile of B-ELNs was analyzed by high-throughput sequencing.A total of 36 miRNAs were found to be enriched in B-ELNs compared with berry tissue,and their potential cross-kingdom human gene targets were further predicted.Results showed that size exclusion chromatography was effective for B-ELN isolation.The most abundant miRNAs in B-ELNs mainly belonged to the miR166 family and miR396 family.Target gene prediction indicated that B-ELNs could potentially regulate pathways related to the human digestive system,immune system and infectious diseases.展开更多
<span style="font-family:""><span style="font-family:Verdana;">In Nagaland ~70% of population lives in rural areas and depends on forest products for livelihood. Being part of the ...<span style="font-family:""><span style="font-family:Verdana;">In Nagaland ~70% of population lives in rural areas and depends on forest products for livelihood. Being part of the biodiversity hotspot, state is rich in biodiversity. The present study was an attempt made to understand the nutritional properties of 22 popular underutilized edible plants (UEP) Kohima, Phek, Tuensang districts. Results revealed moisture content of 22 studied plants ranged between 4.8 to 88.15 g/100g, while protein content varied be</span><span style="font-family:Verdana;">tween 0.00269</span></span><span style="font-family:Verdana;"> - </span><span style="font-family:""><span style="font-family:Verdana;">0.773 g/100g with highest in </span><i><span style="font-family:Verdana;">Terminalia chebula</span></i><span style="font-family:Verdana;"> (0.773</span></span><span style="font-family:""><span style="font-family:Verdana;"> g/100g) fruit while lowest protein content was in </span><i><span style="font-family:Verdana;">Setaria italica</span></i><span style="font-family:Verdana;"> (0.00269 g/100g). To</span><span style="font-family:Verdana;">tal carbohydrate content was between 0.198</span></span><span style="font-family:Verdana;"> - </span><span style="font-family:Verdana;">5.212 g/100g with highest in</span><span style="font-family:""> <i><span style="font-family:Verdana;">Setaria italica</span></i><span style="font-family:Verdana;"> (5.212 g/100g) and lowest in </span><i><span style="font-family:Verdana;">Juglans regia</span></i><span style="font-family:Verdana;"> (0.198 g/100g). Of </span><span><span style="font-family:Verdana;">the 22 samples, maximum antioxidant activity was in </span><i><span style="font-family:Verdana;">Terminalia chebula</span></i></span><span style="font-family:Verdana;"> fruits (37.49 μg/ml) followed by </span><i><span style="font-family:Verdana;">Clerodendrum glandulosum</span></i><span style="font-family:Verdana;"> (65.29 μg/ml) leaves, </span><i><span style="font-family:Verdana;">Phyllanthus emblica </span></i><span style="font-family:Verdana;">(79.08 μg/ml) fruits against Trolox (96.89 μg/ml). Highest total phenol content (TPC) was recorded in </span><i><span style="font-family:Verdana;">Terminalia</span></i> <i><span style="font-family:Verdana;">chebula</span></i><span style="font-family:Verdana;"> (53.11 mg GAE/g) and </span><i><span style="font-family:Verdana;">Rhus chinensis</span></i><span style="font-family:Verdana;"> (43.99 mg</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">GAE/g) while in other 20 crops the values varied from 0.09</span><span style="font-family:Verdana;"> - </span><span style="font-family:Verdana;">8.44 mg</span><span style="font-family:""> </span><span style="font-family:Verdana;">GAE/g. Total flavonoid content (TFC) varied between 0.004</span><span style="font-family:""> </span><span style="font-family:Verdana;">-</span><span style="font-family:""> </span><span style="font-family:Verdana;">43.67 mg</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">QE/g with c</span><i><span style="font-family:Verdana;">lerodendrum glandulosum</span></i><span style="font-family:Verdana;"> (43.67 mg</span></span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">QE/g) and </span><i><span style="font-family:Verdana;">Terminalia chebula</span></i><span style="font-family:Verdana;"> (27.78 mg</span></span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">QE/g) were found to be highest among the 22 plant samples. Findings suggest that these underutilized edible plants should be popularized as they can contribute to nutritional support to </span><span style="font-family:Verdana;">different region of the state for health improvement and cultivated them</span><span style="font-family:Verdana;"> commercially to help and develop various value added local product to improve the livelihood status of the rural population and also add to the economy of the state and region.展开更多
Objective:To evaluate the nutritional composition and elemental constituents of Kedrostis africana and their safety aspect.Methods:Proximate parameters(moisture,ash,crude fibre,crude fat,proteins,and carbohydrate and ...Objective:To evaluate the nutritional composition and elemental constituents of Kedrostis africana and their safety aspect.Methods:Proximate parameters(moisture,ash,crude fibre,crude fat,proteins,and carbohydrate and energy) were evaluated using ALASA methods,and elemental analysis by ICP-OES technique.Results:The results from nutritional analysis showed that the tuber used for this study had a low content of crude fat and high content of ash,crude protein,crude fibre,carbohydrate and energy having the recommended dietary allowances.The tuber was rich in major minerals Na,K,Ca and Mg,there was sufficient amount of trace elements Fe,Cu,and Zn while the anti-nutrients oxalate,phytate,alkaloids,and saponins were detected in amounts that are not harmful according to Food and Agriculture Organization/World Health Organization.Conclusions:The outcome of this study suggests that this wild plant has very good nutritional potentials to meet the recommended dietary allowance and it could be a cheap source of essential nutrients that may ameliorate most nutritional challenges and can contribute remarkably to the amount of nutrient intake in human and animal diet.展开更多
Dioscorea bulbifera is a medicinal and edible plant of the Naxi nationality living in Lijiang area,and its tuber as a vegetable has the functions of clearing away heat and detoxification,and its bulbil has the functio...Dioscorea bulbifera is a medicinal and edible plant of the Naxi nationality living in Lijiang area,and its tuber as a vegetable has the functions of clearing away heat and detoxification,and its bulbil has the functions of clearing away heat and resolving phlegm,relieving cough and relieving asthma,dispersing the accumulation of evils and detoxification,etc.Related studies have shown that it mainly contains steroids,diterpene lactones,flavonoids,polyphenols,alkaloids and so on,and it can also fight cancer,inhibit bacteria,relieve pain,resist inflammation and so on.There is also related literature about hepatotoxicity after taking it.The key technique of traditional vegetable cultivation in Lijiang area is systematically summarized in this paper for reference in the future cultivation process.展开更多
The upsurge of multiple drug resistance(MDR)bacteria substantially diminishes the effectiveness of antibiotic arsenal and therefore intensifies the rate of therapeutic failure.The major factor in MDR is efflux pump-me...The upsurge of multiple drug resistance(MDR)bacteria substantially diminishes the effectiveness of antibiotic arsenal and therefore intensifies the rate of therapeutic failure.The major factor in MDR is efflux pump-mediated resistance.A unique pump can make bacteria withstand a wide range of structurally diverse compounds.Therefore,their inhibition is a promising route to eliminate resistance phenomenon in bacteria.Phytochemicals are excellent alternatives as resistance-modifying agents.They can directly kill bacteria or interact with the crucial events of pathogenicity,thereby decreasing the ability of bacteria to develop resistance.Numerous botanicals display noteworthy efflux pumps inhibitory activities.Edible plants are of growing interest.Likewise,some plant families would be excellent sources of efflux pump inhibitors(EPIs)including Apocynaceae,Berberidaceae,Convolvulaceae,Cucurbitaceae,Fabaceae,Lamiaceae,and Zingiberaceae.Easily applicable methods for screening plant-derived EPIs include checkerboard synergy test,berberine uptake assay and ethidium bromide test.In silico highthroughput virtual detection can be evaluated as a criterion of excluding compounds with efflux substrate-like characteristics,thereby improving the selection process and extending the identification of EPIs.To ascertain the efflux activity inhibition,real-time PCR and quantitative mass spectrometry can be applied.This review emphasizes on efflux pumps and their roles in transmitting bacterial resistance and an update plant-derived EPIs and strategies for identification.展开更多
This study examined the ability of the white lupin to remove mercury (Hg) from a hydroponic system (Hg concentrations 0, 1.25, 2.5, 5 and 10 μmol/L) and from soil in pots and lysimeters (total Hg concentration ...This study examined the ability of the white lupin to remove mercury (Hg) from a hydroponic system (Hg concentrations 0, 1.25, 2.5, 5 and 10 μmol/L) and from soil in pots and lysimeters (total Hg concentration (19.2 ± 1.9) mg/kg availability 0.07%, and (28.9 ± 0.4) mg/kg availability 0.09%, respectively), and investigated the accumulation and distribution of Hg in different parts of the plant. White lupin roots efficiently took up Hg, but its translocation to the harvestable parts of the plant was low. The Hg concentration in the seeds posed no risk to human health according to the recommendations of the World Health Organization, but the shoots should not be used as fodder for livestock, at least when unmixed with other fodder crops. The accumulation of Hg in the hydroponically-grown plants was linear over the concentration range tested. The amount of Hg retained in the roots, relative to the shoots, was almost constant irrespective of Hg dose (90%). In the soil experiments, Hg accumulation increased with exposure time and was the greater in the lysimeter than in the pot experiments. Although Hg removal was the greater in the hydroponic system, revealing the potential of the white lupin to extract Hg, bioaccumulation was the greatest in the lysimeter-grown plants; the latter system more likely reflects the true behaviour of white lupin in the field when Hg availability is a factor that limits Hg removal. The present results suggest that the white lupin could be used in long-term soil reclamation strategies that include the goal of profitable land use in Hg-polluted areas.展开更多
Rosa rugosa Thunb. is a traditional medicinal and food plant in Hotan region,which has important medicinal and economic value. In recent years,the planting area in Hotan region has been expanding. This paper described...Rosa rugosa Thunb. is a traditional medicinal and food plant in Hotan region,which has important medicinal and economic value. In recent years,the planting area in Hotan region has been expanding. This paper described the cultivation techniques,planting models and field management,pest control,harvesting and processing of R. rugosa. Based on the analysis of the advantages and cultivation techniques of developing the rose industry in Hotan region,the paper discussed how to accelerate the development of rose cultivation and deep processing industry in Hotan region.展开更多
Polygonatum odoratum is distributed in several countries around the world as a medicinal and dual-use plant,and its rhizomes are used in China as a traditional Chinese medicine,also as vegetables,foods,functional food...Polygonatum odoratum is distributed in several countries around the world as a medicinal and dual-use plant,and its rhizomes are used in China as a traditional Chinese medicine,also as vegetables,foods,functional foods or tea,with a history of application for more than 2000 years,with precise efficacy and no toxic side effects.However,few reviews are published on its chemical composition and its pharmacological effects.There are many components of P.odoratum,including steroidal saponins,homoisoflavanones,isoflavones,flavonoids,alkaloids,lignin,volatile oil,polysaccharides and lectins.In this review,recent advances of the history and consumption of P.odoratum,the types of chemical components,and the pharmacological effects manifested in antitumour and anticancer,antioxidant,slowing senescence,relieving fatigue and immune regulation are summarized and discussed.Presumably,the main active ingredients of the plant are homoisoflavanones,polysaccharides,saponins,and lectins.The review provides a reference for its development and utilization in the field of functional food and medicine in the future.展开更多
Cultivated hawthorn(Crataegus pinnatifida var.major)is an important medicinal and edible plant with a long history of use for health protection in China.Herein,we provide a de novo chromosomelevel genome sequence of t...Cultivated hawthorn(Crataegus pinnatifida var.major)is an important medicinal and edible plant with a long history of use for health protection in China.Herein,we provide a de novo chromosomelevel genome sequence of the hawthorn cultivar“Qiu Jinxing.”We assembled an 823.41 Mb genome encoding 40571 genes and further anchored the779.24 Mb sequence into 17 pseudo-chromosomes,which account for 94.64%of the assembled genome.Phylogenomic analyses revealed that cultivated hawthorn diverged from other species within the Maleae(apple tribe)at approximately 35.4 Mya.Notably,genes involved in the flavonoid and triterpenoid biosynthetic pathways have been significantly amplified in the hawthorn genome.In addition,our results indicated that the Maleae share a unique ancient tetraploidization event;however,no recent independent whole-genome duplication event was specifically detected in hawthorn.The amplification of non-specific long terminal repeat retrotransposons contributed the most to the expansion of the hawthorn genome.Furthermore,we identified two paleo-sub-genomes in extant species of Maleae and found that these two sub-genomes showed different rearrangement mechanisms.We also reconstructed the ancestral chromosomes of Rosaceae and discussed two possible paleopolyploid origin patterns(autopolyploidization or allopolyploidization)of Maleae.Overall,our study provides an improved context for understanding the evolution of Maleae species,and this new highquality reference genome provides a useful resource for the horticultural improvement of hawthorn.展开更多
OBJECTIVE: To review the role of vegetables to prevent and treat hemorrhoids in Persian Medicine(PM).METHODS: We search main Persian Medicine manuscripts, including the books of Liber Continens,Canon of Medicine, Grea...OBJECTIVE: To review the role of vegetables to prevent and treat hemorrhoids in Persian Medicine(PM).METHODS: We search main Persian Medicine manuscripts, including the books of Liber Continens,Canon of Medicine, Great Elixir, Akbarie’s Medicine,Storehouse of Medicaments and Present for the faithful. Also, it was considered by searching in reference books and published papers with the help of PubMed, Scopus, Google scholar databases.RESULTS: Twelve vegetables, relating to 8 plant families, have been found in PM that their effectiveness involved in laxative, anti-inflammation, antimicrobial, analgesic and wound healing.CONCLUSION: Our findings suggest that 12 Persian Medicine vegetables can be used to prevent and treat hemorrhoids.展开更多
基金supported by the National Natural Science Foundation of China(31701561)。
文摘Edible plant derived exosome-like nanoparticles(ELNs)have been shown to have multiple nutraceutical functions.However,the diversity of plant materials makes the plant derived ELN study challenging.More efforts are still needed to explore the feasible isolation methods of edible plant derived ELNs and the possible roles of food-derived ELNs in improving human health.In this study,a size exclusion chromatography based method was compared with the traditional ultracentrifugation method to isolate blueberry derived ELNs(B-ELNs),and the miRNA profile of B-ELNs was analyzed by high-throughput sequencing.A total of 36 miRNAs were found to be enriched in B-ELNs compared with berry tissue,and their potential cross-kingdom human gene targets were further predicted.Results showed that size exclusion chromatography was effective for B-ELN isolation.The most abundant miRNAs in B-ELNs mainly belonged to the miR166 family and miR396 family.Target gene prediction indicated that B-ELNs could potentially regulate pathways related to the human digestive system,immune system and infectious diseases.
文摘<span style="font-family:""><span style="font-family:Verdana;">In Nagaland ~70% of population lives in rural areas and depends on forest products for livelihood. Being part of the biodiversity hotspot, state is rich in biodiversity. The present study was an attempt made to understand the nutritional properties of 22 popular underutilized edible plants (UEP) Kohima, Phek, Tuensang districts. Results revealed moisture content of 22 studied plants ranged between 4.8 to 88.15 g/100g, while protein content varied be</span><span style="font-family:Verdana;">tween 0.00269</span></span><span style="font-family:Verdana;"> - </span><span style="font-family:""><span style="font-family:Verdana;">0.773 g/100g with highest in </span><i><span style="font-family:Verdana;">Terminalia chebula</span></i><span style="font-family:Verdana;"> (0.773</span></span><span style="font-family:""><span style="font-family:Verdana;"> g/100g) fruit while lowest protein content was in </span><i><span style="font-family:Verdana;">Setaria italica</span></i><span style="font-family:Verdana;"> (0.00269 g/100g). To</span><span style="font-family:Verdana;">tal carbohydrate content was between 0.198</span></span><span style="font-family:Verdana;"> - </span><span style="font-family:Verdana;">5.212 g/100g with highest in</span><span style="font-family:""> <i><span style="font-family:Verdana;">Setaria italica</span></i><span style="font-family:Verdana;"> (5.212 g/100g) and lowest in </span><i><span style="font-family:Verdana;">Juglans regia</span></i><span style="font-family:Verdana;"> (0.198 g/100g). Of </span><span><span style="font-family:Verdana;">the 22 samples, maximum antioxidant activity was in </span><i><span style="font-family:Verdana;">Terminalia chebula</span></i></span><span style="font-family:Verdana;"> fruits (37.49 μg/ml) followed by </span><i><span style="font-family:Verdana;">Clerodendrum glandulosum</span></i><span style="font-family:Verdana;"> (65.29 μg/ml) leaves, </span><i><span style="font-family:Verdana;">Phyllanthus emblica </span></i><span style="font-family:Verdana;">(79.08 μg/ml) fruits against Trolox (96.89 μg/ml). Highest total phenol content (TPC) was recorded in </span><i><span style="font-family:Verdana;">Terminalia</span></i> <i><span style="font-family:Verdana;">chebula</span></i><span style="font-family:Verdana;"> (53.11 mg GAE/g) and </span><i><span style="font-family:Verdana;">Rhus chinensis</span></i><span style="font-family:Verdana;"> (43.99 mg</span></span><span style="font-family:""> </span><span style="font-family:Verdana;">GAE/g) while in other 20 crops the values varied from 0.09</span><span style="font-family:Verdana;"> - </span><span style="font-family:Verdana;">8.44 mg</span><span style="font-family:""> </span><span style="font-family:Verdana;">GAE/g. Total flavonoid content (TFC) varied between 0.004</span><span style="font-family:""> </span><span style="font-family:Verdana;">-</span><span style="font-family:""> </span><span style="font-family:Verdana;">43.67 mg</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">QE/g with c</span><i><span style="font-family:Verdana;">lerodendrum glandulosum</span></i><span style="font-family:Verdana;"> (43.67 mg</span></span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">QE/g) and </span><i><span style="font-family:Verdana;">Terminalia chebula</span></i><span style="font-family:Verdana;"> (27.78 mg</span></span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">QE/g) were found to be highest among the 22 plant samples. Findings suggest that these underutilized edible plants should be popularized as they can contribute to nutritional support to </span><span style="font-family:Verdana;">different region of the state for health improvement and cultivated them</span><span style="font-family:Verdana;"> commercially to help and develop various value added local product to improve the livelihood status of the rural population and also add to the economy of the state and region.
基金financial support of the National Research Foundation (NRF 85294),South Africa
文摘Objective:To evaluate the nutritional composition and elemental constituents of Kedrostis africana and their safety aspect.Methods:Proximate parameters(moisture,ash,crude fibre,crude fat,proteins,and carbohydrate and energy) were evaluated using ALASA methods,and elemental analysis by ICP-OES technique.Results:The results from nutritional analysis showed that the tuber used for this study had a low content of crude fat and high content of ash,crude protein,crude fibre,carbohydrate and energy having the recommended dietary allowances.The tuber was rich in major minerals Na,K,Ca and Mg,there was sufficient amount of trace elements Fe,Cu,and Zn while the anti-nutrients oxalate,phytate,alkaloids,and saponins were detected in amounts that are not harmful according to Food and Agriculture Organization/World Health Organization.Conclusions:The outcome of this study suggests that this wild plant has very good nutritional potentials to meet the recommended dietary allowance and it could be a cheap source of essential nutrients that may ameliorate most nutritional challenges and can contribute remarkably to the amount of nutrient intake in human and animal diet.
基金Training Program for the Fourth Batch of Young and Middle-aged Academic and Technical Leaders in Lijiang CitySpecial Project of"100 Lijiang Agricultural Talents"in Lijiang CityReserve Talent Project for Young and Middle-aged Academic and Technical Leaders in Yunnan Province.
文摘Dioscorea bulbifera is a medicinal and edible plant of the Naxi nationality living in Lijiang area,and its tuber as a vegetable has the functions of clearing away heat and detoxification,and its bulbil has the functions of clearing away heat and resolving phlegm,relieving cough and relieving asthma,dispersing the accumulation of evils and detoxification,etc.Related studies have shown that it mainly contains steroids,diterpene lactones,flavonoids,polyphenols,alkaloids and so on,and it can also fight cancer,inhibit bacteria,relieve pain,resist inflammation and so on.There is also related literature about hepatotoxicity after taking it.The key technique of traditional vegetable cultivation in Lijiang area is systematically summarized in this paper for reference in the future cultivation process.
基金We are grateful to Chinese Academy of Sciences(CAS)for jointly supports(project No.2018PB0089 to AJS and project No.2019VBA0026 to SDS)under CAS President’s International Fellowship Initiative(CAS-PIFI)projectsthe Major Project for Special Technology Innovation of Hubei Province(Grant No.2017AHB054 to MG).
文摘The upsurge of multiple drug resistance(MDR)bacteria substantially diminishes the effectiveness of antibiotic arsenal and therefore intensifies the rate of therapeutic failure.The major factor in MDR is efflux pump-mediated resistance.A unique pump can make bacteria withstand a wide range of structurally diverse compounds.Therefore,their inhibition is a promising route to eliminate resistance phenomenon in bacteria.Phytochemicals are excellent alternatives as resistance-modifying agents.They can directly kill bacteria or interact with the crucial events of pathogenicity,thereby decreasing the ability of bacteria to develop resistance.Numerous botanicals display noteworthy efflux pumps inhibitory activities.Edible plants are of growing interest.Likewise,some plant families would be excellent sources of efflux pump inhibitors(EPIs)including Apocynaceae,Berberidaceae,Convolvulaceae,Cucurbitaceae,Fabaceae,Lamiaceae,and Zingiberaceae.Easily applicable methods for screening plant-derived EPIs include checkerboard synergy test,berberine uptake assay and ethidium bromide test.In silico highthroughput virtual detection can be evaluated as a criterion of excluding compounds with efflux substrate-like characteristics,thereby improving the selection process and extending the identification of EPIs.To ascertain the efflux activity inhibition,real-time PCR and quantitative mass spectrometry can be applied.This review emphasizes on efflux pumps and their roles in transmitting bacterial resistance and an update plant-derived EPIs and strategies for identification.
基金The Spanish Ministry of Education and Science, Project CTM2005-04809/TECNO, financially supported this research
文摘This study examined the ability of the white lupin to remove mercury (Hg) from a hydroponic system (Hg concentrations 0, 1.25, 2.5, 5 and 10 μmol/L) and from soil in pots and lysimeters (total Hg concentration (19.2 ± 1.9) mg/kg availability 0.07%, and (28.9 ± 0.4) mg/kg availability 0.09%, respectively), and investigated the accumulation and distribution of Hg in different parts of the plant. White lupin roots efficiently took up Hg, but its translocation to the harvestable parts of the plant was low. The Hg concentration in the seeds posed no risk to human health according to the recommendations of the World Health Organization, but the shoots should not be used as fodder for livestock, at least when unmixed with other fodder crops. The accumulation of Hg in the hydroponically-grown plants was linear over the concentration range tested. The amount of Hg retained in the roots, relative to the shoots, was almost constant irrespective of Hg dose (90%). In the soil experiments, Hg accumulation increased with exposure time and was the greater in the lysimeter than in the pot experiments. Although Hg removal was the greater in the hydroponic system, revealing the potential of the white lupin to extract Hg, bioaccumulation was the greatest in the lysimeter-grown plants; the latter system more likely reflects the true behaviour of white lupin in the field when Hg availability is a factor that limits Hg removal. The present results suggest that the white lupin could be used in long-term soil reclamation strategies that include the goal of profitable land use in Hg-polluted areas.
基金Supported by Western Youth Scholar Program of Chinese Academy of Sciences(2018-XBQNXZ-A-002)Autonomous Region Scientific Special Commissioner Poverty Alleviation Action Project (2019C01OO8)。
文摘Rosa rugosa Thunb. is a traditional medicinal and food plant in Hotan region,which has important medicinal and economic value. In recent years,the planting area in Hotan region has been expanding. This paper described the cultivation techniques,planting models and field management,pest control,harvesting and processing of R. rugosa. Based on the analysis of the advantages and cultivation techniques of developing the rose industry in Hotan region,the paper discussed how to accelerate the development of rose cultivation and deep processing industry in Hotan region.
基金This research was supported financially by the scientific research project of the Hebei Administration of Traditional Chinese Medicine,China(2022098,2022365)the Doctoral Research Foundation of Hebei University of Chinese Medicine,China(BSZ2020007,BSZ2021019)+1 种基金the Modern Agricultural Technology Innovation Team Project in Hebei Province,China(HBCT2018060205)the Traditional Chinese Medicine Resources Survey Project of China(Z135080000022).
文摘Polygonatum odoratum is distributed in several countries around the world as a medicinal and dual-use plant,and its rhizomes are used in China as a traditional Chinese medicine,also as vegetables,foods,functional foods or tea,with a history of application for more than 2000 years,with precise efficacy and no toxic side effects.However,few reviews are published on its chemical composition and its pharmacological effects.There are many components of P.odoratum,including steroidal saponins,homoisoflavanones,isoflavones,flavonoids,alkaloids,lignin,volatile oil,polysaccharides and lectins.In this review,recent advances of the history and consumption of P.odoratum,the types of chemical components,and the pharmacological effects manifested in antitumour and anticancer,antioxidant,slowing senescence,relieving fatigue and immune regulation are summarized and discussed.Presumably,the main active ingredients of the plant are homoisoflavanones,polysaccharides,saponins,and lectins.The review provides a reference for its development and utilization in the field of functional food and medicine in the future.
基金supported by grants from National Natural Science Foundation of China(32060237 to T.Z.and 32060085 to Q.Q.)funding from the European Research Council(ERC)under the European Union’s Horizon 2020 research and innovation program(No.833522)from Ghent University(Methusalem funding,BOF.MET.2021.0005.01)。
文摘Cultivated hawthorn(Crataegus pinnatifida var.major)is an important medicinal and edible plant with a long history of use for health protection in China.Herein,we provide a de novo chromosomelevel genome sequence of the hawthorn cultivar“Qiu Jinxing.”We assembled an 823.41 Mb genome encoding 40571 genes and further anchored the779.24 Mb sequence into 17 pseudo-chromosomes,which account for 94.64%of the assembled genome.Phylogenomic analyses revealed that cultivated hawthorn diverged from other species within the Maleae(apple tribe)at approximately 35.4 Mya.Notably,genes involved in the flavonoid and triterpenoid biosynthetic pathways have been significantly amplified in the hawthorn genome.In addition,our results indicated that the Maleae share a unique ancient tetraploidization event;however,no recent independent whole-genome duplication event was specifically detected in hawthorn.The amplification of non-specific long terminal repeat retrotransposons contributed the most to the expansion of the hawthorn genome.Furthermore,we identified two paleo-sub-genomes in extant species of Maleae and found that these two sub-genomes showed different rearrangement mechanisms.We also reconstructed the ancestral chromosomes of Rosaceae and discussed two possible paleopolyploid origin patterns(autopolyploidization or allopolyploidization)of Maleae.Overall,our study provides an improved context for understanding the evolution of Maleae species,and this new highquality reference genome provides a useful resource for the horticultural improvement of hawthorn.
基金Supported by a PhD thesis by the Vice Chancellor for Research,Shahid Beheshti University of Medical Sciences
文摘OBJECTIVE: To review the role of vegetables to prevent and treat hemorrhoids in Persian Medicine(PM).METHODS: We search main Persian Medicine manuscripts, including the books of Liber Continens,Canon of Medicine, Great Elixir, Akbarie’s Medicine,Storehouse of Medicaments and Present for the faithful. Also, it was considered by searching in reference books and published papers with the help of PubMed, Scopus, Google scholar databases.RESULTS: Twelve vegetables, relating to 8 plant families, have been found in PM that their effectiveness involved in laxative, anti-inflammation, antimicrobial, analgesic and wound healing.CONCLUSION: Our findings suggest that 12 Persian Medicine vegetables can be used to prevent and treat hemorrhoids.