A case of 9p deletion syndrome with congenital infantile glaucoma,effective method of diagnosis,and treatment

Dear Editor,I am Dr.Jia X from the Department of Ophthalmology,Second Xiangya Hospital,Central South University,Changsha,China.I write to present a rare case report of 9p deletion syndrome with congenital infantile glaucoma in an infant,accompanying with an effective method of both diagnosis and treatment.

Novel implementation of homogenization method to predict effective properties of periodic materials

Representative volume element （RVE） method and asymptotic homogenization （AH） method are two widely used methods in predicting effective properties of pe- riodic materials. This paper develops a novel implementa- tion of the AH method, which has rigorous mathematical foundation of the AH method, and also simplicity as the RVE method. This implementation can be easily realized using commercial software as a black box, and can use all kinds of elements available in commercial software to model unit cells with rather complicated microstructures, so the model may remain a fairly small scale. Several examples were car- fled out to demonstrate the simplicity and effectiveness of the new implementation.

Efficiency and Effectiveness Method versus ε-NTU Method with Application in Finned Flat Tube Compact Heat Exchanger with Water-Ethylene Glycol as Nanofluid Base of Iron Oxide Nanoparticles

This work aims to establish comparisons between two models used for the performance of heat exchangers. The chosen system, in this case, consists of a heat exchanger used in automotive radiators flat finned tube type. Water and ethylene glycol compound as base fluid and volume fractions of iron oxide nanoparticles (Fe3O4) are used as a refrigerant. The quantities determined in this work are the nanofluid exit temperature, the air exit temperature, the absolute error between the models for heat transfer rate, and Effectiveness. The quantities that constitute parameters, independent variables, are the airflow, represented by the Reynolds number, and the iron oxide volume fraction. Ethylene Glycol 50% compound has slightly better thermal performance than pure water and reduces the reactive effect of water on the environment, increasing the average life of the equipment. The absolute relative error between the models is less than 20% and presents maximum values with the increase of the nanoparticle volume fraction and growth in the Reynolds number for the air.

An Effective Thermal Splicing Method to Join Fluoride and Silica Fibers for a High Power Regime

A repeatable and simple thermal splicing method for low loss splice between fluoride and silica fibers is presented. The minimum splicing loss of 0.58 dB is achieved experimentally with this approach, Meanwhile, the power capacity of this splicing joint is also tested with a high power fiber laser. The maximum input power is up to 15 W, only limited by the available power of the laser source. To the best of our knowledge, this is the first report on thermal splicing between fluoride and silica fibers operating in a high power regime without any complicated ion-assisted deposition process.

Dynamics of Quantum State and Effective Hamiltonian with Vector Differential Form of Motion Method

Effective Hamiltonians in periodically driven systems have received widespread attention for realization of novel quantum phases, non-equilibrium phase transition, and Majorana mode. Recently, the study of effective Hamiltonian using various methods has gained great interest. We consider a vector differential equation of motion to derive the effective Hamiltonian for any periodically driven two-level system, and the dynamics of the spin vector are an evolution under the Bloch sphere. Here, we investigate the properties of this equation and show that a sudden change of the effective Hamiltonian is expected. Furthermore, we present several exact relations, whose expressions are independent of the different starting points. Moreover, we deduce the effective Hamiltonian from the high-frequency limit, which approximately equals the results in previous studies. Our results show that the vector differential equation of motion is not affected by a convergence problem, and thus, can be used to numerically investigate the effective models in any periodic modulating system. Finally, we anticipate that the proposed method can be applied to experimental platforms that require time-periodic modulation, such as ultracold atoms and optical lattices.

Numerical investigation of the effects of soil-structure and granular material-structure interaction on the seismic response of a flat-bottom reinforced concrete silo

In this work,a numerical study of the effects of soil-structure interaction(SSI)and granular material-structure interaction(GSI)on the nonlinear response and seismic capacity of flat-bottomed storage silos is conducted.A series of incremental dynamic analyses(IDA)are performed on a case of large reinforced concrete silo using 10 seismic recordings.The IDA results are given by two average IDA capacity curves,which are represented,as well as the seismic capacity of the studied structure,with and without a consideration of the SSI while accounting for the effect of GSI.These curves are used to quantify and evaluate the damage of the studied silo by utilizing two damage indices,one based on dissipated energy and the other on displacement and dissipated energy.The cumulative energy dissipation curves obtained by the average IDA capacity curves with and without SSI are presented as a function of the base shear,and these curves allow one to obtain the two critical points and the different limit states of the structure.It is observed that the SSI and GSI significantly influence the seismic response and capacity of the studied structure,particularly at higher levels of PGA.Moreover,the effect of the SSI reduces the damage index of the studied structure by 4%.

Types and Correction Methods of Matrix Effect during Zircon LA-ICP-MS U-Pb Dating

Matrix effect primarily impacts the accuracy and precision of zircon LA-ICP-MS U-Pb data.This paper describes three types of matrix effect in zircon LA-ICPMS U-Pb dating,i.e.,the element matrix effect,high Ddpa or uranium matrix effect and alpha dose matrix effect,and illustrates the correction of these three effects.In addition,we point out the limitation and possible problems of the existing correction methods.

Numerical Predictions of the Effective Thermal Conductivity of the Rigid Polyurethane Foam

A reconstruction method is proposed for the polyurethane foam and then a complete numerical method is developed to predict the effective thermal conductivity of the polyurethane foam. The finite volume method is applied to solve the 2D heterogeneous pure conduction. The lattice Boltzmann method is adopted to solve the 1D homogenous radiative transfer equation rather than Rosseland approximation equation. The lattice Boltzmann method is then adopted to solve 1D homogeneous conduction-radiation energy transport equation considering the combined effect of conduction and radiation. To validate the accuracy of the present method, the hot disk method is adopted to measure the effective thermal conductivity of the polyurethane foams at different temperature. The numerical results agree well with the experimental data. Then, the influences of temperature, porosity and cell size on the effective thermal conductivity of the polyurethane foam are investigated. The results show that the effective thermal conductivity of the polyurethane foams increases with temperature; and the effective thermal conductivity of the polyurethane foams decreases with increasing porosity while increases with the cell size.

C^1 natural element method for strain gradient linear elasticity and its application to microstructures

C^1 natural element method （C^1 NEM） is applied to strain gradient linear elasticity, and size effects on mi crostructures are analyzed. The shape functions in C^1 NEM are built upon the natural neighbor interpolation （NNI）, with interpolation realized to nodal function and nodal gradient values, so that the essential boundary conditions （EBCs） can be imposed directly in a Galerkin scheme for partial differential equations （PDEs）. In the present paper, C^1 NEM for strain gradient linear elasticity is constructed, and sev- eral typical examples which have analytical solutions are presented to illustrate the effectiveness of the constructed method. In its application to microstructures, the size effects of bending stiffness and stress concentration factor （SCF） are studied for microspeciem and microgripper, respectively. It is observed that the size effects become rather strong when the width of spring for microgripper, the radius of circular perforation and the long axis of elliptical perforation for microspeciem come close to the material characteristic length scales. For the U-shaped notch, the size effects decline obviously with increasing notch radius, and decline mildly with increasing length of notch.

Seismic fluid identification using a nonlinear elastic impedance inversion method based on a fast Markov chain Monte Carlo method

Elastic impedance inversion with high efficiency and high stability has become one of the main directions of seismic pre-stack inversion. The nonlinear elastic impedance inversion method based on a fast Markov chain Monte Carlo （MCMC） method is proposed in this paper, combining conventional MCMC method based on global optimization with a preconditioned conjugate gradient （PCG） algorithm based on local optimization, so this method does not depend strongly on the initial model. It converges to the global optimum quickly and efficiently on the condition that effi- ciency and stability of inversion are both taken into consid- eration at the same time. The test data verify the feasibility and robustness of the method, and based on this method, we extract the effective pore-fluid bulk modulus, which is applied to reservoir fluid identification and detection, and consequently, a better result has been achieved.

Optical simulation of in-plane-switching blue phase liquid crystal display using the finite-difference time-domain method

The finite-difference time-domain method is used to simulate the optical characteristics of an in-plane switching blue phase liquid crystal display.Compared with the matrix optic methods and the refractive method,the finite-difference timedomain method,which is used to directly solve Maxwell＇s equations,can consider the lateral variation of the refractive index and obtain an accurate convergence effect.The simulation results show that e-rays and o-rays bend in different directions when the in-plane switching blue phase liquid crystal display is driven by the operating voltage.The finitedifference time-domain method should be used when the distribution of the liquid crystal in the liquid crystal display has a large lateral change.

On the parameters for electrocaloric effect predicted by indirect method

The influences of specific heat capacity CP, temperature step ？T, electric field step ？E, and initial electric field E1 on predicted electrocaloric（EC） temperature ？T of monodomain Ba TiO3 are examined by combining the Maxwell equation and phenomenological theory. Since the procedure is similar to indirect measurement of the EC effect, the results can serve as a reference for experiments. The results suggest that（i） it is reasonable to use zero-field CP,（ii） optimized ？T should be 2 K,（iii） it is better to keep △E 〈 EC, and（iv） E1〈 EC. Here, EC is the coercive field of material.

Dynamic thermo-mechanical coupled response of random particulate composites:A statistical two-scale method

This paper focuses on the dynamic thermo-mechanical coupled response of random particulate composite materials. Both the inertia term and coupling term are considered in the dynamic coupled problem. The formulation of the problem by a statistical second-order two-scale （SSOTS） analysis method and the algorithm procedure based on the finite-element difference method are presented. Numerical results of coupled cases are compared with those of uncoupled cases. It shows that the coupling effects on temperature, thermal flux, displacement, and stresses are very distinct, and the micro- characteristics of particles affect the coupling effect of the random composites. Furthermore, the coupling effect causes a lag in the variations of temperature, thermal flux, displacement, and stresses.

Effects of Numerical Methods on the Calculation of Developing Plane Channel Flow

In wall-bounded turbulent flow calculations, the past focus has been directed to the modelling of the Reynolds-stress gradients. Not much attention has been paid to the effects of the numerical methods used to calculate these terms and the modelled equations. Discrepancies between model calculations and measurements are quite often attributed to incorrect modelling, while the suitability and accuracy of the numerical methods used are seldom scrutinized. Instead, alternate near-wall and Reynolds-stress models are proposed to remedy the incorrect turbulent flow calculations. On the other hand, if care is not taken in the numerical treatment of the Reynolds-stress gradient terms, physically unrealistic results and solution instability could occur. Previous studies by the author and his collaborators on the effects of numerical methods have shown that some of the more commonly used numerical methods could enhance numerical stability in the solution procedure but would introduce considerable inaccuracy to the results. The flow cases chosen to demonstrate these inaccuracies are a backstep flow and flow in a square duct, where flow complexities are present. The current investigation attempts to show that the above-mentioned effects of numerical methods could also occur in the calculation of a developing plane channel flow, where flow complexities are absent. In addition, this study shows that the results thus obtained lead to a predicted skin friction coefficient that is influenced more by the numerical method used than by the turbulence model invoked. Together, these results show that numerical treatment of the Reynolds-stress gradients in the equations play an important role, even for a developing plane channel flow.

The K Method for Estimating Earthquake Activity Parameters and Effect of the Boundary Uncertainty of the Source Region:Discussion on the Seismic Zoning Method

Two aspects of a new method,which can be used for seismic zoning,are introduced in this paper.On the one hand,the approach to estimate b value and annual activity rate proposed by Kijko and Sellevoll needs to use the earthquake catalogue.The existing earthquake catalogue contains both historical and recent instrumental data sets and it is inadequate to use only one part.Combining the large number of historical events with recent complete records and taking the magnitude uncertainty into account,Kijko’s method gives the maximum likelihood estimation of b value and annual activity rate,which might be more realistic.On the other hand,this method considers the source zone boundary uncertainty in seismic hazard analysis,which means the earthquake activity rate across a boundary of a source zone changes smoothly instead of abruptly and avoids too large a gradient in the calculated results.

A study of the effective Hamiltonian method for decay dynamics

The decay dynamic of an excited quantum emitter(QE)is one of the most important contents in quantum optics.It has been widely applied in the field of quantum computing and quantum state manipulation.When the electromagnetic environment is described by several pseudomodes,the effective Hamiltonian method based on the multi-mode Jaynes-Cummings model provides a clear physical picture and a simple and convenient way to solve the decay dynamics.However,in previous studies,only the resonant modes are taken into account,while the non-resonant contributions are ignored.In this work,we study the applicability and accuracy of the effective Hamiltonian method for the decay dynamics.We consider different coupling strengths between a two-level QE and a gold nanosphere.The results for dynamics by the resolvent operator technique are used as a reference.Numerical results show that the effective Hamiltonian method provides accurate results when the two-level QE is resonant with the plasmon.However,when the detuning is large,the effective Hamiltonian method is not accurate.In addition,the effective Hamiltonian method cannot be applied when there is a bound state between the QE and the plasmon.These results are of great significance to the study of the decay dynamics in micro-nano structures described by quasi-normal modes.

Angular dependence of multiple-bit upset response in static random access memories under heavy ion irradiation

Experimental evidence is presented relevant to the angular dependences of multiple-bit upset （MBU） rates and patterns in static random access memories （SRAMs） under heavy ion irradiation. The single event upset （SEU） cross sections under tilted ion strikes are overestimated by 23.9%-84.6%, compared with under normally incident ion with the equivalent linear energy transfer （LET） value of 41 MeV/（mg/cm2）, which can be partially explained by the fact that the MBU rate for tilted ions of 30° is 8.5%-9.8% higher than for normally incident ions. While at a lower LET of - 9.5 MeV/（mg/cm2）, no clear discrepancy is observed. Moreover, since the ion trajectories at normal and tilted incidences are different, the predominant double-bit upset （DBU） patterns measured are different in both conditions. Those differences depend on the LET values of heavy ions and devices under test. Thus, effective LET method should be used carefully in ground-based testing of single event effects （SEE） sensitivity, especially in MBU-sensitive devices.

Parameter analysis of a photonic crystal fiber with raised-core index profile based on effective index method

Photonic crystal fibers （PCFs） with a stepped raised-core profile and one layer equally spaced holes in the cladding are analyzed. Using effective index method and considering a raised step refractive index difference between the index of the core and the effective index of the cladding, we improve the characteristic parameters such as numerical aperture and V-parameter, and reduce its bending loss to about one tenth of a conventional PCF. Implementing such a structure in PCFs may be one step forward to achieve low loss PCFs for communication applications.