Theaflavins(TFs),as the major polyphenolic components of fermented tea,possess beneficial effects on human health.In this study,the effervescent tablets based on theaflavins were developed.The optimal formulation of T...Theaflavins(TFs),as the major polyphenolic components of fermented tea,possess beneficial effects on human health.In this study,the effervescent tablets based on theaflavins were developed.The optimal formulation of TF effervescent tablets was obtained by response surface methodology with the Box-Behnken design.Then,the physiochemical properties were evaluated,including hardness,friability,effervescent time and pH of the solution.At last,the antioxidant ability of TF effervescent tablets was studied through DPPH and ABTS radical scavenging assay.According to the results,the optimal formulation of the tablets contained TF powder 9.09%,disintegrating agent 43.80%(the weight ratio of citric acid and sodium bicarbonate was 1:1),aspartame 1.86%,PEG-6003%,and mannitol in balance.With the wet granulation method,the TF effervescent tablets displayed suitable hardness,fast disintegration time,good color,pleasant taste and high antioxidant activity.This study demonstrated that the TF effervescent tablets could be a valuable product for the supplement market and contribute to promoting practical application of TFs.展开更多
Rose is one of the farming products that used as an accessory plantation, which is also known to contain vitamin C and anthocyanins which can be used as an antioxidant. The purpose of this study is to identify the col...Rose is one of the farming products that used as an accessory plantation, which is also known to contain vitamin C and anthocyanins which can be used as an antioxidant. The purpose of this study is to identify the colour effect of flower through the quality effervescent tablet, to know the interaction between the flower colour and the sugar type through the quality effervescent rose tablet. This study was done with two steps. Step I was divided into 2 levels of examinations using simple random： Rose colouring, M1 （dark red） and M2 （pink）, while step II consisted of three levels of examinations, those were G 1 （sucrose）, G2 （dextrose）, and G3 （sorbitol）. The result showed that the dark red colour has a better extract pigment quality, the level of the light color （L） was 77.3 and the redness level （b＋） was 25.033. The best rose effervescent tablet was produced by the combination of M 1 G3 （dark red： corn sugar/sorbitol）, that has 8.179% of water content; the solute velocity was 0.029 g/sec; the lightness level （L） was 84.133, the redness level （a＋） was 18.3. The product of the rose effervescent drinks has a value of 6.46 pH; viscosities 342.867 cps and total of sugar 52.150%.展开更多
目的研究宫颈高危型HPV感染应用重组人干扰素α2b阴道泡腾胶囊治疗的作用。方法选取100例宫颈高危型HPV感染患者,根据随机数字表法分为研究组与一般组,各50例。一般组定期随访不做任何处理,研究组采用重组人干扰素α2b阴道泡腾胶囊治疗...目的研究宫颈高危型HPV感染应用重组人干扰素α2b阴道泡腾胶囊治疗的作用。方法选取100例宫颈高危型HPV感染患者,根据随机数字表法分为研究组与一般组,各50例。一般组定期随访不做任何处理,研究组采用重组人干扰素α2b阴道泡腾胶囊治疗。比较两组转阴情况、治疗前后生活质量评分。结果研究组转阴率高于(62.00 vs 22.00)%一般组(P<0.05)。治疗后,研究组生活质量评分(75.98±10.52 vs 85.98±11.03)分高于一般组(P<0.05)。结论宫颈高危型HPV感染患者实施重组人干扰素α2b阴道泡腾胶囊治疗,可有效提高转阴率,改善患者生活质量,值得临床推广。展开更多
基金Supported by Hubei Key Laboratory of Economic Forest Germplasm Improvement and Resources Comprehensive Utilization,Hubei Collaborative Innovation Center for the Characteristic Resources Exploitation of Dabie Mountains Fund(2021CX06)。
文摘Theaflavins(TFs),as the major polyphenolic components of fermented tea,possess beneficial effects on human health.In this study,the effervescent tablets based on theaflavins were developed.The optimal formulation of TF effervescent tablets was obtained by response surface methodology with the Box-Behnken design.Then,the physiochemical properties were evaluated,including hardness,friability,effervescent time and pH of the solution.At last,the antioxidant ability of TF effervescent tablets was studied through DPPH and ABTS radical scavenging assay.According to the results,the optimal formulation of the tablets contained TF powder 9.09%,disintegrating agent 43.80%(the weight ratio of citric acid and sodium bicarbonate was 1:1),aspartame 1.86%,PEG-6003%,and mannitol in balance.With the wet granulation method,the TF effervescent tablets displayed suitable hardness,fast disintegration time,good color,pleasant taste and high antioxidant activity.This study demonstrated that the TF effervescent tablets could be a valuable product for the supplement market and contribute to promoting practical application of TFs.
文摘Rose is one of the farming products that used as an accessory plantation, which is also known to contain vitamin C and anthocyanins which can be used as an antioxidant. The purpose of this study is to identify the colour effect of flower through the quality effervescent tablet, to know the interaction between the flower colour and the sugar type through the quality effervescent rose tablet. This study was done with two steps. Step I was divided into 2 levels of examinations using simple random： Rose colouring, M1 （dark red） and M2 （pink）, while step II consisted of three levels of examinations, those were G 1 （sucrose）, G2 （dextrose）, and G3 （sorbitol）. The result showed that the dark red colour has a better extract pigment quality, the level of the light color （L） was 77.3 and the redness level （b＋） was 25.033. The best rose effervescent tablet was produced by the combination of M 1 G3 （dark red： corn sugar/sorbitol）, that has 8.179% of water content; the solute velocity was 0.029 g/sec; the lightness level （L） was 84.133, the redness level （a＋） was 18.3. The product of the rose effervescent drinks has a value of 6.46 pH; viscosities 342.867 cps and total of sugar 52.150%.
文摘目的研究宫颈高危型HPV感染应用重组人干扰素α2b阴道泡腾胶囊治疗的作用。方法选取100例宫颈高危型HPV感染患者,根据随机数字表法分为研究组与一般组,各50例。一般组定期随访不做任何处理,研究组采用重组人干扰素α2b阴道泡腾胶囊治疗。比较两组转阴情况、治疗前后生活质量评分。结果研究组转阴率高于(62.00 vs 22.00)%一般组(P<0.05)。治疗后,研究组生活质量评分(75.98±10.52 vs 85.98±11.03)分高于一般组(P<0.05)。结论宫颈高危型HPV感染患者实施重组人干扰素α2b阴道泡腾胶囊治疗,可有效提高转阴率,改善患者生活质量,值得临床推广。
