Objective To analyze the clinical data of patients who suffered from hypertensive intra cerebral hemorrhage (HICH) in West China Hospital of Sichuan University from 2006 to 2009,to evaluate the efficacy and prognosis ...Objective To analyze the clinical data of patients who suffered from hypertensive intra cerebral hemorrhage (HICH) in West China Hospital of Sichuan University from 2006 to 2009,to evaluate the efficacy and prognosis of surgical treatment and conservative treatment in HICH, to investigate the surgical and展开更多
The current quality control（QC） pattern for Chinese materia medica（CMM） lacks suitable methods and indicators to evaluate their safety and efficacy effectively, which impedes the smooth development of CMM. In this...The current quality control（QC） pattern for Chinese materia medica（CMM） lacks suitable methods and indicators to evaluate their safety and efficacy effectively, which impedes the smooth development of CMM. In this review, main problems of the current QC pattern for CMM, principally focused on the content determination of constituents,were summarized and the inspiration from the QC of biological products was introduced. With the aim at introducing a suitable tool to the QC of CMM, biopotency assay and its feasibility in the QC pattern for CMM were analyzed and confirmed by relevant researches with years of practice. From the applications of biopotency assays in the QC of CMM in the last 10 years, we propose that biopotency assays should be an integral part of the QC pattern for CMM, for these assays can make the QC indicators related to the clinical safety and efficacy, supplementing the existed QC system of CMM.展开更多
文摘Objective To analyze the clinical data of patients who suffered from hypertensive intra cerebral hemorrhage (HICH) in West China Hospital of Sichuan University from 2006 to 2009,to evaluate the efficacy and prognosis of surgical treatment and conservative treatment in HICH, to investigate the surgical and
基金National Natural Science Foundation of China (81274026)China Scholarship Council,Open Research Fund of the State Key Laboratory Breeding Base of Systematic Research,Development and Utilization of Chinese Medicinal Resources,China Postdoctoral Science Foundation(2013M532130)
文摘The current quality control（QC） pattern for Chinese materia medica（CMM） lacks suitable methods and indicators to evaluate their safety and efficacy effectively, which impedes the smooth development of CMM. In this review, main problems of the current QC pattern for CMM, principally focused on the content determination of constituents,were summarized and the inspiration from the QC of biological products was introduced. With the aim at introducing a suitable tool to the QC of CMM, biopotency assay and its feasibility in the QC pattern for CMM were analyzed and confirmed by relevant researches with years of practice. From the applications of biopotency assays in the QC of CMM in the last 10 years, we propose that biopotency assays should be an integral part of the QC pattern for CMM, for these assays can make the QC indicators related to the clinical safety and efficacy, supplementing the existed QC system of CMM.
