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深海真菌Trichobotrys effuse DFFSCS021的次级代谢产物研究
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作者 罗琴琴 陈子明 +5 位作者 曾金凤 曾玲 郑翠平 陆根兰 王锂韫 孙玉林 《广西科学》 CAS 2020年第5期558-563,共6页
通过多种现代化波谱手段,对深海真菌Trichobotrys effuse DFFSCS021的次级代谢产物进行挖掘。采用硅胶柱层析、Sephadex LH-20凝胶柱层析和高效液相色谱等分离技术,对该菌株发酵产物中的化学成分进行研究,并运用核磁共振(NMR)、质谱(MS... 通过多种现代化波谱手段,对深海真菌Trichobotrys effuse DFFSCS021的次级代谢产物进行挖掘。采用硅胶柱层析、Sephadex LH-20凝胶柱层析和高效液相色谱等分离技术,对该菌株发酵产物中的化学成分进行研究,并运用核磁共振(NMR)、质谱(MS)和文献比对鉴定其化学结构。结果显示:从该菌株的发酵产物中共分离得到5个单体化合物,分别为1,3-dimethyluracil(1)、[2E,7E]-9-oxo-2,7-decadienoic acid(2)、periconianones H(3)、botryosphaeridione(4)和2-hydroxy-(4-octyloxy)benzophenone(5),化合物1-5均是首次从该菌株中分离得到。化合物3对5株肿瘤细胞株HepG-2、Eca109、KG-1a、PC-3和Hep2均未显示出细胞毒活性,仅对Hela显示弱的抑制活性。实验结果不仅丰富了该菌属的化学成分类型,而且也增强了深海真菌的研究价值。 展开更多
关键词 深海真菌 Trichobotrys effuse DFFSCS021 次级代谢 结构鉴定 细胞毒活性
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经鼓室口咽鼓管球囊扩张术的疗效及咽鼓管功能的影响
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作者 谢先荣 付亚峰 刘伟清 《中国耳鼻咽喉头颈外科》 CSCD 2024年第2期122-124,共3页
目的探讨经鼓室口咽鼓管球囊扩张(balloon dilatation Eustachian tuboplasty,BET)联合腺样体消融术对慢性分泌性中耳炎(chronic secretory otitis media,CSOM)患儿的疗效及咽鼓管功能的影响。方法选取2020年6月~2022年12月间在中山市... 目的探讨经鼓室口咽鼓管球囊扩张(balloon dilatation Eustachian tuboplasty,BET)联合腺样体消融术对慢性分泌性中耳炎(chronic secretory otitis media,CSOM)患儿的疗效及咽鼓管功能的影响。方法选取2020年6月~2022年12月间在中山市小榄人民医院就诊的CSOM患儿82例作为研究对象,采用随机数字表法分为对照组和观察组,每组41例。对照组接受腺样体消融术+鼓膜切开置管术治疗,观察组接受腺样体消融术+鼓膜切开置管术+BET术。比较两组手术相关指标及住院时间、临床症状、咽鼓管功能、临床疗效及随访6个月并发症及复发情况。结果两组术中出血量比较,差异无统计学意义(P>0.05),与对照组相比,观察组手术时间更长,住院时间更短(P<0.05)。与对照组相比,观察组中耳积液消失时间、耳鸣消失时间、鼓膜愈合时间、听力恢复时间均更短(P<0.05)。与治疗前相比,治疗后两组咽鼓管评分(Eustachian tube score,ETS)升高、咽鼓管功能障碍评分量表(Eustachian tube dysfunction questionnaire-7,ETDQ-7)评分降低(P<0.05),观察组ETS评分高于对照组,ETDQ-7评分则低于对照组(P<0.05)。观察组临床总有效率高于对照组,差异具有统计学意义(P<0.05)。两组并发症发生率比较,差异无统计学意义(14.63%vs.9.76%,P>0.05),与对照组相比,观察组复发率更低,差异具有统计学意义(21.95%vs.2.44%,P<0.05)。结论经鼓室口BET联合腺样体消融术有助于提高CSOM患儿的临床疗效,改善咽鼓管功能,促进术后恢复,减少复发率,且并发症发生率低。 展开更多
关键词 伴渗出液中耳炎(Otitis Media with Effusion) 咽鼓管(Eustachian Tube) 扩张术(Dilatation) 腺样体切除术(Adenoidectomy) 咽鼓管球囊扩张术(balloon dilatation Eustachian tuboplasty) 咽鼓管鼓室口(tympanic opening of Eustachian tube)
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Pulmonary Edema and Pleural Effusion Detection Using Efficient Net-V1-B4 Architecture and AdamW Optimizer from Chest X-Rays Images
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作者 Anas AbuKaraki Tawfi Alrawashdeh +4 位作者 Sumaya Abusaleh Malek Zakarya Alksasbeh Bilal Alqudah Khalid Alemerien Hamzah Alshamaseen 《Computers, Materials & Continua》 SCIE EI 2024年第7期1055-1073,共19页
This paper presents a novelmulticlass systemdesigned to detect pleural effusion and pulmonary edema on chest Xray images,addressing the critical need for early detection in healthcare.A new comprehensive dataset was f... This paper presents a novelmulticlass systemdesigned to detect pleural effusion and pulmonary edema on chest Xray images,addressing the critical need for early detection in healthcare.A new comprehensive dataset was formed by combining 28,309 samples from the ChestX-ray14,PadChest,and CheXpert databases,with 10,287,6022,and 12,000 samples representing Pleural Effusion,Pulmonary Edema,and Normal cases,respectively.Consequently,the preprocessing step involves applying the Contrast Limited Adaptive Histogram Equalization(CLAHE)method to boost the local contrast of the X-ray samples,then resizing the images to 380×380 dimensions,followed by using the data augmentation technique.The classification task employs a deep learning model based on the EfficientNet-V1-B4 architecture and is trained using the AdamW optimizer.The proposed multiclass system achieved an accuracy(ACC)of 98.3%,recall of 98.3%,precision of 98.7%,and F1-score of 98.7%.Moreover,the robustness of the model was revealed by the Receiver Operating Characteristic(ROC)analysis,which demonstrated an Area Under the Curve(AUC)of 1.00 for edema and normal cases and 0.99 for effusion.The experimental results demonstrate the superiority of the proposedmulti-class system,which has the potential to assist clinicians in timely and accurate diagnosis,leading to improved patient outcomes.Notably,ablation-CAM visualization at the last convolutional layer portrayed further enhanced diagnostic capabilities with heat maps on X-ray images,which will aid clinicians in interpreting and localizing abnormalities more effectively. 展开更多
关键词 Image classification decision support system EfficientNet-V1-B4 AdamW optimizer pulmonary edema pleural effusion chest X-rays
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Pleural effusion,ascites,colon ulcers and hematochezia:What we can learn from the diagnostic process of a patient with plasma cell myeloma:A case report
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作者 Ming-Xian Yan 《World Journal of Clinical Cases》 SCIE 2024年第22期5196-5207,共12页
BACKGROUND Plasma cell myeloma(PCM)is characterized by hypercalcemia,renal impairment,anemia,and bone destruction.While pleural effusion,ascites,abdominal pain,and bloody stool are common manifestations of lung diseas... BACKGROUND Plasma cell myeloma(PCM)is characterized by hypercalcemia,renal impairment,anemia,and bone destruction.While pleural effusion,ascites,abdominal pain,and bloody stool are common manifestations of lung disease or gastrointestinal disorders,they are rarely observed in patients with PCM.CASE SUMMARY A 66-year-old woman presented with complaints of recurrent chest tightness,wheezing,and abdominal bloating accompanied by bloody stools.Computed tomography revealed pleural effusion and ascites.Pleural effusion tests showed inflammation,but the T-cell spot test and carcinoembryonic antigen were negative.Endoscopy showed colonic mucosal edema with ulcer formation and local intestinal lumen stenosis.Echocardiography revealed enlarged atria and reduced left ventricular systolic function.The diagnosis remained unclear.Further testing revealed elevated blood light chain lambda and urine immunoglobulin levels.Blood immunofixation electrophoresis was positive for immunoglobulin G lambda type.Smear cytology of the bone marrow showed a high proportion of plasma cells,accounting for about 4.5%.Histopathological examination of the bone marrow suggested PCM.Flow cytometry showed abnormal plasma cells with strong expression of CD38,CD138,cLambda,CD28,CD200,and CD117.Fluorescence in situ hybridization gene testing of the bone marrow suggested 1q21 gene amplification,but cytogenetic testing showed no clonal abnormalities.Colonic mucosa and bone marrow biopsy tissues were negative for Highman Congo red staining.The patient was finally diagnosed with PCM.CONCLUSION A diagnosis of PCM should be considered in older patients with pleural effusion,ascites,and multi-organ injury. 展开更多
关键词 Plasma cell myeloma Pleural effusion ASCITES HEMATOCHEZIA Colon ulcers Bone marrow aspirate Case report
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Subdural effusion associated with COVID-19 encephalopathy: A case report
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作者 Zhi-Yuan Xue Zhong-Lin Xiao +5 位作者 Ming Cheng Tao Xiang Xiao-Li Wu Qiao-Ling Ai Yang-Ling Wu Tao Yang 《World Journal of Clinical Cases》 SCIE 2024年第10期1799-1803,共5页
BACKGROUND The precise mechanism by which severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)impacts the central nervous system remains unclear,with manifestations spanning from mild symptoms(e.g.,olfactory an... BACKGROUND The precise mechanism by which severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)impacts the central nervous system remains unclear,with manifestations spanning from mild symptoms(e.g.,olfactory and gustatory deficits,hallucinations,and headache)to severe complications(e.g.,stroke,seizures,encephalitis,and neurally demyelinating lesions).The occurrence of single-pass subdural effusion,as described below,is extremely rare.CASE SUMMARY A 56-year-old male patient presented with left-sided limb weakness and slurred speech as predominant clinical symptoms.Through comprehensive imaging and diagnostic assessments,he was diagnosed with cerebral infarction complicated by hemorrhagic transformation affecting the right frontal,temporal,and parietal regions.In addition,an intracranial infection with SARS-CoV-2 was identified during the rehabilitation process;consequently,an idiopathic subdural effusion developed.Remarkably,the subdural effusion underwent absorption within 6 d,with no recurrence observed during the 3-month follow-up.CONCLUSION Subdural effusion is a potentially rare intracranial complication associated with SARS-CoV-2 infection. 展开更多
关键词 Cerebral infarction Hemorrhagic transformation Subdural effusion COVID-19 encephalopathy Novel coronavirus infection Brain fog Case report
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Arthroscopic synovectomy for synovial hyperplasia in chronic knee gouty arthritis:A case report
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作者 Ghuna A Utoyo Calvin Calvin 《World Journal of Orthopedics》 2024年第11期1101-1108,共8页
BACKGROUND Chronic synovitis due to chronic knee gouty arthritis(KGA)resulting in synovial hyperplasia has not been documented in the current literature,and thus the optimal management for this condition remains uncle... BACKGROUND Chronic synovitis due to chronic knee gouty arthritis(KGA)resulting in synovial hyperplasia has not been documented in the current literature,and thus the optimal management for this condition remains unclear.This case report discusses a 34-year-old man with a history of chronic KGA who presented with recurrent knee effusion resulting from synovial hyperplasia.CASE SUMMARY A 34-year-old man presented to our outpatient clinic with a 5-year recurrent knee effusion and a history of chronic KGA.Symptoms persisted despite serial aspiration and urate-lowering medication(febuxostat 80 mg once daily)for 2 months.Diagnostic arthroscopy was performed due to the recalcitrant symptoms.Intraoperatively,tophi deposition and excessive thickening of the synovial membrane were observed.Synovial biopsy and partial synovectomy were performed,revealing chronic synovitis with synovial hyperplasia that was consistent with chronic KGA.At follow-up after 6 months,the patient reported no further episode of knee effusion.CONCLUSION Arthroscopic synovectomy for synovial hyperplasia in chronic KGA sufficiently eradicates the symptoms of recurrent knee effusion. 展开更多
关键词 Chronic knee gouty arthritis Recurrent knee effusion Synovial hyperplasia Arthroscopic synovectomy Case report
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Endoscopic vacuum assisted closure therapy for esophagopericardial fistula in a 16-year-old male:A case report
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作者 Simón Muñoz-González Samir Quejada-Cuesta +1 位作者 Daniel González-Arroyave Carlos M Ardila 《World Journal of Gastrointestinal Endoscopy》 2024年第9期533-539,共7页
BACKGROUND Esophagopericardial fistula(EPF)is a rare,life-threatening condition with limited scientific literature and no established management guidelines.This case report highlights a successful multidisciplinary ap... BACKGROUND Esophagopericardial fistula(EPF)is a rare,life-threatening condition with limited scientific literature and no established management guidelines.This case report highlights a successful multidisciplinary approach and the innovative use of endoscopic vacuum assisted closure(endoVAC)therapy in treating this complex condition.CASE SUMMARY A 16-year-old male with a history of esophageal atresia and colon interposition presented with progressive chest pain,fever,and dyspnea.Imaging revealed an EPF with associated pleural and pericardial effusions.Initial management with an esophageal stent failed,prompting the use of an endoVAC system.The patient underwent multiple endoVAC device changes and received broad-spectrum antibiotics and nutritional support.The fistula successfully closed,and the patient recovered,demonstrating no new symptoms at a 6-month follow-up.CONCLUSION EndoVAC therapy can effectively manage EPF,providing a minimally invasive treatment option. 展开更多
关键词 Esophagopericardial fistula Endoscopic vacuum assisted closure Esophageal atresia Multidisciplinary approach Pleural effusion Case report
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放疗前后鼓室置管治疗鼻咽癌伴分泌性中耳炎的疗效对比观察
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作者 骆小华 邓锐 +2 位作者 陈华娇 王惠曦 王朝永 《中国耳鼻咽喉头颈外科》 CSCD 2024年第7期467-469,共3页
目的评估放疗前后鼓室置管对行放疗的鼻咽癌伴分泌性中耳炎(OME)患者的治疗价值。方法回顾性分析2017年7月~2022年2月重庆大学附属涪陵医院确诊的鼻咽癌伴OME行放疗的49例患者,根据鼓室置管时机的不同将纳入病例分为观察组和对照组。观... 目的评估放疗前后鼓室置管对行放疗的鼻咽癌伴分泌性中耳炎(OME)患者的治疗价值。方法回顾性分析2017年7月~2022年2月重庆大学附属涪陵医院确诊的鼻咽癌伴OME行放疗的49例患者,根据鼓室置管时机的不同将纳入病例分为观察组和对照组。观察组(n=21例)在放疗前即行鼓室置管,对照组(n=28例)在放疗后再行鼓室置管,对比分析两组患者的治疗效果、生活质量及远期并发症等因素。生活质量评估指标主要包括:听力改善(纯音听阈气导AC提升值)、耳鸣改善(THI耳鸣残疾评估量表得分)及咽鼓管功能(ETDQ-7咽鼓管功能障碍评分)。结果随访时间超过1年,观察组总有效率为81.0%(17/21),对照组总有效率为75.0%(21/28),差异无统计学意义(χ^(2)=0.022,P>0.05);观察组AC提升值为17.57±8.483,对照组AC提升值为19.86±5.848,差异无统计学意义(t=-1.117,P>0.05);观察组治疗后THI得分0.95±3.390,对照组THI得分为2.50±4.948,差异无统计学意义(t=-1.180,P>0.05);观察组治疗后ETDQ-7得分为9.86±6.027,对照组ETDQ-7得分为9.36±2.947,差异无统计学意义(t=0.383,P>0.05);远期并发症如化脓性中耳炎、鼓膜穿孔、耳道溢液等,观察组的发生率为19.1%(4/21),对照组发生率为25.0%(7/28),差异无统计学意义(χ^(2)=0.022,P>0.05)。结论鼻咽癌伴OME在放疗前或放疗后行鼓室置管治疗效果均较好,并有效改善患者听力、耳鸣和咽鼓管功能,但两组无明显差异且均有不低的远期并发症发生,因此放疗前不宜行不必要的鼓室置管。 展开更多
关键词 鼻咽癌(Nasopharyngeal Carcinoma) 伴渗出液中耳炎(Otitis Media with Effusion) 对比研究(Comparative Study) 鼓膜置管术(ventilation tube insertion) 放疗(radiotherapy)
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鼓室内注射地塞米松联合盐酸氨溴索治疗分泌性中耳炎的临床疗效
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作者 毛向清 《中国耳鼻咽喉头颈外科》 CSCD 2024年第10期665-667,共3页
目的鼓室内注射地塞米松联合盐酸氨溴索对分泌性中耳炎患者的疗效分析。方法回顾性分析2023年2月~2024年2月乌兰察布市中心医院诊治的分泌性中耳炎患者84例,根据不同的治疗方法分为观察组和对照组,每组各42例。观察组采用鼓室内注射地... 目的鼓室内注射地塞米松联合盐酸氨溴索对分泌性中耳炎患者的疗效分析。方法回顾性分析2023年2月~2024年2月乌兰察布市中心医院诊治的分泌性中耳炎患者84例,根据不同的治疗方法分为观察组和对照组,每组各42例。观察组采用鼓室内注射地塞米松与盐酸氨溴索联合治疗,对照组为鼓室内注射地塞米松治疗,比较两组患者的总体疗效、炎性因子、纯音听阈及不良反应发生率情况。结果观察组总有效率为95.24%(40/42),对照组总有效率为78.57%(33/42),差异比较有统计学意义(χ^(2)=5.126,P<0.05)。肿瘤坏死因子α(TNF-α)和白细胞介素8(IL-8)在两组治疗前差异比较无统计学意义(P均>0.05),治疗后有统计学意义(P均<0.05)。纯音听阈在两组患者治疗前差异比较无统计学意义(P>0.05),而治疗后有统计学意义(P<0.05)。观察组治疗期间的不良反应发生率为9.52%(4/42),对照组为7.14%(3/42),差异比较无统计学意义(χ^(2)=0.265,P>0.05)。结论鼓室内注射地塞米松联合盐酸氨溴索治疗分泌性中耳炎,可改善患者的炎性水平并提升听力,是一种安全可靠的治疗方法。 展开更多
关键词 伴渗出液中耳炎(Otitis Media with Effusion) 地塞米松(Dexamethasone) 盐酸氨溴索(ambroxol hydrochlorid) 鼓室内注射(intrameranic injection)
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Subxyphoid Pericardial Drainage for Tuberculous Pericardial Effusion in Antananarivo
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作者 Tsirimalala Rajaobelison Zakarimanana Lucas Randimbinirina +3 位作者 Maharo Ramifehiarivo Manoahasina Ranaliarinosy Rabarison Toky Mamin’ny Aina Rajaonanahary Andriamihaja Jean-Claude Rakotoarisoa 《World Journal of Cardiovascular Surgery》 2024年第2期21-31,共11页
Introduction: Tuberculosis is the leading cause of pericardial effusion in sub-Saharan African countries. The aim of this study was to describe the diagnosis and the surgical management of tuberculous pericardial effu... Introduction: Tuberculosis is the leading cause of pericardial effusion in sub-Saharan African countries. The aim of this study was to describe the diagnosis and the surgical management of tuberculous pericardial effusion in low-income country. Methods: This was a retrospective and descriptive study performed at Vascular Surgery Unit for 10 years-period (from January 2012 to December 2021), including all cases of drainage of pericardial effusion due to tuberculosis. Results: Sixty-seven cases were recorded, including 38 males (56.71%) and 29 women (43.28%). The average age was 35.47 years old. Patients lived in urban areas in 67.16% of cases. Thirteen patients (13.43%) had a previous history of pulmonary tuberculosis. The most common risk factors for tuberculosis infection were malnourishment (80.59%), indoor air pollution (77.61%) and close contact with tuberculosis patient (40.29%). The commonest symptom were dyspnea, (95.52%), chest pain (89.55%), fever (67.16%), tachycardia (95.52%) and cough (80.59%). Twenty-seven patients (39.02%) presented clinical signs of cardiac tamponade. Electrocardiogram showed sinus tachycardia (97.53%) with microvoltage (39.02%). Chest-X-ray showed cardiomegaly (100%) and pleural effusion (56.71%). Echocardiography showed moderate (43.28%) and large (56.71%) pericardial effusion. All patients underwent subxiphoid pericardial drainage. Mycobacterium tuberculosis detection via GeneXpert test of pericardial effusion were positive in 38.80% of patients. Pericardial biopsies confirmed the diagnosis of tuberculosis in 41.79%. The mortality rate was 8.95%. Conclusion: Subxiphoid pericardial drainage reduced thr risk of cardiac tamponade in patients with massive pericardial effusion. Histopathology of pericardial biopsies made a definitive diagnosis for tuberculosis. 展开更多
关键词 TUBERCULOSIS ECHOCARDIOGRAPHY Pericardial Effusion SURGERY Cardiac Tamponade
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Bacteriological Profile of Effusion Fluids Infections at Charles De Gaulle University Pediatric Hospital from 2017 to 2020
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作者 Kambiré Dinanibè Ouédraogo Oumarou +14 位作者 Tiendrebéogo Salam Tondé Issa Tamboura Mamadou Zida Sylvie Kpoda Dissinviel Sagna Tani Compaoré T. Rebeca Zouré Abdou-Azaque Soubeiga R. Serge Théophile Sawadogo Stanislas Ilboudo Maïmouna Rouamba Hortense Ouédraogo Wenkouni Henri Gautier Ouédraogo-Traoré Rasmata Sanou Mahamoudou 《Open Journal of Medical Microbiology》 2024年第2期146-163,共18页
Introduction: Microbiology of effusion fluids in children in Burkina Faso is characterized by the scarcity of data. This work aimed to study the bacteriological and antibiotics susceptibility profile of bacteria invol... Introduction: Microbiology of effusion fluids in children in Burkina Faso is characterized by the scarcity of data. This work aimed to study the bacteriological and antibiotics susceptibility profile of bacteria involved in effusion fluid infections in paediatrics in order to improve the choice of probabilistic antibiotics therapy. Methods: A cross-sectional, descriptive study was used in children aged 0 to 15 years from 2017 to 2020 at the Charles De Gaulle Pediatric University Hospital Center (CHUP-CDG) in Ouagadougou. Classical bacteriology methods such as macroscopy, Gram staining, identification galleries and antibiotics susceptibility testing were used. Results: Of 231 samples, 64 bacteria were isolated. The most common bacterial strains of pleural fluid were Staphylococcus aureus (25%) and 40% for Enterobacteriaceae. Of the peritoneal fluid, 77% were Enterobacteriaceae with 57% Escherichia coli;and from joint fluid, 33% were S. aureus and 22% for P. aeruginosa. The overall susceptibility profile showed 29% extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL), 10% methicillin-resistant S. aureus (MRSA), and 8% carbapenemases. Conclusion: Bacteriological profile is characterized by ESBL-producing Enterobacteriaceae and MRSA. The most active antibiotics were macrolides, aminoglycosides, and cefoxitin (methicillin) for Gram-positive cocci, carbapenems, and aminoglycosides for Gram-negative bacilli. Then, the monitoring of antibiotics resistance must be permanent. 展开更多
关键词 Bacteriological Profile Effusion Fluid INFECTIONS
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Comparison of efficacy of lung ultrasound and chest X-ray in diagnosing pulmonary edema and pleural effusion in ICU patients: A single centre, prospective, observational study
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作者 Kunal Tewari Sumanth Pelluru +5 位作者 Deepak Mishra Nitin Pahuja Akash Ray Mohapatra Jyotsna Sharma Om Bahadur Thapa Manjot Multani 《Open Journal of Anesthesiology》 2024年第3期41-50,共10页
Background and Aims While chest X-ray (CXR) has been a conventional tool in intensive care units (ICUs) to identify lung pathologies, computed tomography (CT) scan remains the gold standard. Use of lung ultrasound (LU... Background and Aims While chest X-ray (CXR) has been a conventional tool in intensive care units (ICUs) to identify lung pathologies, computed tomography (CT) scan remains the gold standard. Use of lung ultrasound (LUS) in resource-rich ICUs is still under investigation. The present study compares the utility of LUS to that of CXR in identifying pulmonary edema and pleural effusion in ICU patients. In addition, consolidation and pneumothorax were analyzed as secondary outcome measures. Material and Methods This is a prospective, single centric, observational study. Patients admitted in ICU were examined for lung pathologies, using LUS by a trained intensivist;and CXR done within 4 hours of each other. The final diagnosis was ascertained by an independent senior radiologist, based on the complete medical chart including clinical findings and the results of thoracic CT, if available. The results were compared and analyzed. Results Sensitivity, specificity and diagnostic accuracy of LUS was 95%, 94.4%, 94.67% for pleural effusion;and 98.33%, 97.78%, 98.00% for pulmonary edema respectively. Corresponding values with CXR were 48.33%, 76.67%, 65.33% for pleural effusion;and 36.67%, 82.22% and 64.00% for pulmonary edema respectively. Sensitivity, specificity and diagnostic accuracy of LUS was 91.30%, 96.85%, 96.00% for consolidation;and 100.00%, 79.02%, 80.00% for pneumothorax respectively. Corresponding values with CXR were 60.87%, 81.10%, 78.00% for consolidation;and 71.3%, 97.20%, 96.00% for pneumothorax respectively. Conclusion LUS has better diagnostic accuracy in diagnosis of pleural effusion and pulmonary edema when compared with CXR and is thus recommended as an effective alternative for diagnosis of these conditions in acute care settings. Our study recommends that a thoracic CT scan can be avoided in most of such cases. 展开更多
关键词 Chest X ray (CXR) CONSOLIDATION Pulmonary edema Pleural effusion Lung ultrasound (LUS) PNEUMOTHORAX
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耳内窥镜下鼓膜置管联合腺样体切除术与鼓膜穿刺治疗分泌性中耳炎患儿的临床疗效比较
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作者 王霞 张万红 吕高峰 《中国耳鼻咽喉头颈外科》 CSCD 2024年第4期263-265,272,共4页
目的探讨耳内窥镜下鼓膜置管联合腺样体切除术治疗分泌性中耳炎(OME)患儿的临床疗效。方法选取2021年1月~2022年3月SOM患儿120例,按术式分为穿刺组(n=60)和置管组(n=60),穿刺组给予耳内窥镜下鼓膜穿刺联合腺样体切除术,置管组给予耳内... 目的探讨耳内窥镜下鼓膜置管联合腺样体切除术治疗分泌性中耳炎(OME)患儿的临床疗效。方法选取2021年1月~2022年3月SOM患儿120例,按术式分为穿刺组(n=60)和置管组(n=60),穿刺组给予耳内窥镜下鼓膜穿刺联合腺样体切除术,置管组给予耳内窥镜下鼓膜置管联合腺样体切除术,比较两组积液消退时间、听觉脑干诱发电位(ABR)阈值、ABRⅠ波潜伏期、干扰素γ(IFN-γ)、白细胞介素6(IL-6)、肿瘤坏死因子α(TNF-α)、治疗效果以及并发症。结果置管组积液消退时间显著低于穿刺组,差异有统计学意义(P<0.05);穿刺组和置管组术后ABR、ABRⅠ波潜伏期、IFN-γ、IL-6和TNF-α均显著低于术前(P均<0.05);置管组术后ABR、ABRⅠ波潜伏期、IFN-γ、IL-6和TNF-α均显著低于穿刺组,差异有统计学意义(P均<0.05);置管组治疗有效率显著高于穿刺组,差异有统计学意义(P<0.05);置管组并发症发生率显著低于穿刺组,差异有统计学意义(P<0.05)。结论耳内窥镜下鼓膜置管联合腺样体切除术可有效改善SOM患儿听力及炎症,有利于提高疗效,且可减少并发症,值得临床推广。 展开更多
关键词 内窥镜检查(Endoscopy) 耳镜检查(Otoscopy) 鼓膜穿刺术(Tympanocentesis) 腺样体切除术(Adenoidectomy) 伴渗出液中耳炎(Otitis Media with Effusion) 儿童(Child) 听力检查(Hearing Tests) 手术后并发症(Postoperative Complications) 鼓膜置管(grommet insertion)
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Thermomechanical Characterization of Laterite Matrix Reinforced with Typha Material for Thermal Insulation in Building
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作者 El Hadji Abdoul Aziz Cisse Papa Touty Traore +2 位作者 Alphousseyni Ghabo Mor Ndiaye Issa Diagne 《Materials Sciences and Applications》 2024年第10期450-463,共14页
Every person, in every country and on every continent, will be affected in one way or another by climate change. A climate cataclysm is looming on the horizon due to greenhouse gas emissions. This explains a strong de... Every person, in every country and on every continent, will be affected in one way or another by climate change. A climate cataclysm is looming on the horizon due to greenhouse gas emissions. This explains a strong demand for air conditioning in the years to come, hence the need for good thermal insulation at a lower cost. However, a policy of prevention, adaptation, and resilience is necessary for the protection of the environment in the future. This work aims to respond to the United Nations SDGs 7, 11 and 13. This paper presents the results of thermomechanical characterizations of the Typha additive (0%, 5%, 10%, 15%, 20%) in laterite matrices. First, we carried out a thermal characterization using the asymmetric hot plane method, which led to thermal conductivity and effusivity in different proportions. Next, mechanical tests were carried out to determine the traction and compression of each material with a matest press. Those which made it possible to obtain results according to the percentage for the thermal tests: a conductivity varying between 0.7178 W/m·K to 0.0597 W/m·K and an effusivity varying between 942.5392 J/m2·K·s1/2 at 287.0855 J/m2·K·s1/2 and for mechanical tests: traction varying between 0.035 MPa to 0.034 MPa and compression varying between 0.1115 MPa to 0.0805 MPa for the different samples. The exploitation of the results allowed us to study the conductivity, effusivity, traction, and compression as a function of their densities. 展开更多
关键词 Characterization Asymmetrical Hot Plane CONDUCTIVITY EFFUSIVITY TRACTION Compression Press and Density
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Physical and Thermo-Mechanical Properties of Composite Materials Based on Raw Earth and Crushed Palm Leaf Fibers (Borassus aethiopum)
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作者 Mouhamadou Nabi Kane Mapathe Ndiaye +1 位作者 Pape Moussa Touré Adama Dione 《Materials Sciences and Applications》 2024年第9期358-377,共20页
The objective of this study is to seek solutions to reduce the impact of buildings on climate change and to promote the use of local bio-sourced or geo-sourced materials for sustainable construction. Different samples... The objective of this study is to seek solutions to reduce the impact of buildings on climate change and to promote the use of local bio-sourced or geo-sourced materials for sustainable construction. Different samples of raw earth from 3 sites were taken in the commune of Mlomp. Geotechnical tests showed that the raw earth samples from sites 2 and 3 have more clay fraction while site 1 contains more sand. The fact of integrating fibers from crushed palm leaves (Borassus aethiopum) (2%, 4% and 6%) into the 3 raw earth samples reduced the mechanical resistance to compression and traction of the 3 raw earths. The experimental results of thermal tests on samples of earth mixtures with crushed Palma leaf fibers show a decrease in thermal conductivity as well as thermal effusivity as the percentages increase (2%, 4% and 6%) of fibers in raw earth for the 3 sites. This shows that this renewable composite material can help improve the thermal insulation of building envelopes. 展开更多
关键词 Raw Earth Palma Leaf Fibers Ecological Composite Materials PHYSICAL Thermo-Mechanical Thermal Conductivity Thermal Effusivity
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低龄儿童分泌性中耳炎诊疗进展 被引量:22
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作者 陈敏 张雪溪 +3 位作者 刘薇 杨扬 郝津生 张杰 《中国耳鼻咽喉头颈外科》 CSCD 2016年第8期448-453,共6页
本文简要介绍低龄儿童分泌性中耳炎定义、自然史及预后;系统综述低龄儿童分泌性中耳炎病因、诊断及其治疗。其中病因主要包括机械及功能性阻塞、感染和免疫3个方面;诊断强调临床表现和耳镜检查、声导抗测试、听力筛查及检查的综合结果;... 本文简要介绍低龄儿童分泌性中耳炎定义、自然史及预后;系统综述低龄儿童分泌性中耳炎病因、诊断及其治疗。其中病因主要包括机械及功能性阻塞、感染和免疫3个方面;诊断强调临床表现和耳镜检查、声导抗测试、听力筛查及检查的综合结果;治疗涵括观察、药物、物理和手术治疗4个方面。 展开更多
关键词 中耳炎 伴渗出液(0titi S Media with Effusion) 儿童(Child) 临床方案(Clinical Protocols)
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儿童分泌性中耳炎相关因素研究 被引量:10
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作者 董亦晗 刘鹏 +2 位作者 李士新 刘石 王景丽 《中国耳鼻咽喉头颈外科》 CSCD 2013年第1期16-16,共1页
分泌性中耳炎(otitis media with effusion,0ME)是引起小儿听力下降的重要原因之一,对儿童的言语、语言和认知发育有十分显著的影响,是小儿耳鼻咽喉科常见病。有关OME病因和发病机制至今仍不很明确,为了提高对儿童OME的认识,现... 分泌性中耳炎(otitis media with effusion,0ME)是引起小儿听力下降的重要原因之一,对儿童的言语、语言和认知发育有十分显著的影响,是小儿耳鼻咽喉科常见病。有关OME病因和发病机制至今仍不很明确,为了提高对儿童OME的认识,现将大庆油田总医院耳鼻咽喉科2007年1月-2011年10月收治的124例(196耳)儿童OME患儿的临床资料分析如下。 展开更多
关键词 儿童(Child) 中耳炎 伴渗出液(Otitis Media with Effusion) 临床方案(Clinical Protocols)
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鼓膜打孔及腺样体切除术治疗儿童分泌性中耳炎 被引量:23
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作者 马丽晶 王军 +3 位作者 叶京英 李秋珍 杨庆文 韩德民 《中国耳鼻咽喉头颈外科》 北大核心 2006年第9期647-648,共2页
分泌性中耳炎(secretory otitis media,SOM)是以中耳积液(包括浆液、黏液或浆-黏液)及听力下降为主要特征的中耳炎性疾病,小儿发病率较高,是引起儿童听力下降的常见原因之一.腺样体肥大是导致儿童分泌性中耳炎的常见病因,我科近年... 分泌性中耳炎(secretory otitis media,SOM)是以中耳积液(包括浆液、黏液或浆-黏液)及听力下降为主要特征的中耳炎性疾病,小儿发病率较高,是引起儿童听力下降的常见原因之一.腺样体肥大是导致儿童分泌性中耳炎的常见病因,我科近年来应用腺样体切割吸引器在鼻内镜直视下切除腺样体,配合CO2激光鼓膜打孔治疗儿童分泌性中耳炎取得了较好的疗效,现报道告如下. 展开更多
关键词 中耳炎 伴渗出液(Otitis Media with Effusion) 激光(Lasers) 腺样体切除术(Adenoidectomy) 鼓膜(Tympanic Membrane) 儿童(Child)
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分泌性中耳炎动物模型建立方法及研究进展 被引量:22
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作者 李卓豪 徐果 张志钢 《中华耳科学杂志》 CSCD 北大核心 2015年第4期757-760,共4页
分泌性中耳炎(otitis media with effusion,OME)是以中耳积液及听力下降为主要特征的中耳非化脓性炎性疾病,是耳科的常见病。80%的儿童3岁前曾出现过急性中耳炎的表现,以OME为主[1]。然而,一部分患者可以自愈,并且不再复发,另外一部... 分泌性中耳炎(otitis media with effusion,OME)是以中耳积液及听力下降为主要特征的中耳非化脓性炎性疾病,是耳科的常见病。80%的儿童3岁前曾出现过急性中耳炎的表现,以OME为主[1]。然而,一部分患者可以自愈,并且不再复发,另外一部分的患者则迁延不愈。OME的病因与发病机制复杂,目前学者普遍认为,OME病因有咽鼓管阻塞、感染、变应性反应,通常涉及多因素,最新的研究表明基因易感性也是一个重要的发病因素。 展开更多
关键词 分泌性中耳炎 动物模型建立 中耳积液 咽鼓管阻塞 急性中耳炎 变应性反应 炎性疾病 OTITIS 咽鼓管功能 EFFUSION
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腺样体切除联合鼓膜穿刺术治疗儿童分泌性中耳炎 被引量:20
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作者 胡文良 孙学威 李玲香 《中国耳鼻咽喉头颈外科》 CSCD 2015年第3期147-148,共2页
分泌性中耳炎(otitis media with effusion,OME)是引起听力障碍及言语发育迟缓的常见疾病,儿童的发病率明显高于成年人,病因复杂,咽鼓管功能障碍、感染等可能是导致儿童OME主要原因[1,2]。目前发现腺样体肥大除引起鼻堵、打鼾及阻塞性... 分泌性中耳炎(otitis media with effusion,OME)是引起听力障碍及言语发育迟缓的常见疾病,儿童的发病率明显高于成年人,病因复杂,咽鼓管功能障碍、感染等可能是导致儿童OME主要原因[1,2]。目前发现腺样体肥大除引起鼻堵、打鼾及阻塞性睡眠呼吸低通气综合征外,也可以导致OME反复发作。目前以药物保守治疗或手术治疗为主,手术治疗包括鼓膜穿刺术、腺样体切除术联合鼓膜穿刺术、鼓膜置管术等。本文通过对一部分OME患儿病例回顾性分析,旨在探讨手术方式对儿童OME转归的影响,现报道如下。 展开更多
关键词 儿童(Child) 中耳炎 伴渗出液(Otitis Media with Effusion) 腺样体切除术(Adenoidectomy) 鼓膜(Tympanic Membrane) 咽鼓管(Eustachian Tube)
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