Elasticity is of profound significance to evaluating the function of a biological soft tissue. When the elasticity of a tissue is macroscopically changed, it means that the biological function of the tissue is abnorma...Elasticity is of profound significance to evaluating the function of a biological soft tissue. When the elasticity of a tissue is macroscopically changed, it means that the biological function of the tissue is abnormal and some disease or injury may occur. In the present work, an elastometer is developed to measure the elasticity of biological soft tissues. The measurement is based on the indentation method and the force is measured by the bending of the cantilever. The force-indentation data of the soft tissue is experimentally measured by this elastometer and Young＇s modulus of the tissue is calculated using the Hertz-Sneddon model. For comparison, a numerical model for the indentation method is established using the finite element method. The difference between the actual modulus and the measured modulus is discussed. The effect of the thickness of the specimen on the measurement is investigated. Young＇s moduli of beef, porcine liver and porcine kidney are experimentally measured. The results indicate that our elastometer is effective in measuring Young＇s modulus of a soft tissue quantitatively.展开更多
A measurement scheme carried out in a tank is designed to obtain the compressionaland shear-wave velocities of a large elastic material.A hydrophone is used to receive the high frequency acoustic signals which penetra...A measurement scheme carried out in a tank is designed to obtain the compressionaland shear-wave velocities of a large elastic material.A hydrophone is used to receive the high frequency acoustic signals which penetrate the tested material,in order to determine the transmission time from the source to the hydrophone,the transmission time is also calculated according to the ray acoustic theory in layered media.A cost function is built based on the measured and the calculated transmission time,then the compressional- and shear-wave velocities can be obtained using the optimization algorithm.Compared with the traditional measurement scheme,this approach can not only get the 2 kinds of sound velocities in the tested material at the same time,but also keep the integrality of the tested material.With the proposed measurement system,the uncertainty of measurement results is less than 3.5%.展开更多
基金Supported by the National Natural Science Foundation of China under Grant Nos 11274342,11304353,11404245 and 11474042
文摘Elasticity is of profound significance to evaluating the function of a biological soft tissue. When the elasticity of a tissue is macroscopically changed, it means that the biological function of the tissue is abnormal and some disease or injury may occur. In the present work, an elastometer is developed to measure the elasticity of biological soft tissues. The measurement is based on the indentation method and the force is measured by the bending of the cantilever. The force-indentation data of the soft tissue is experimentally measured by this elastometer and Young＇s modulus of the tissue is calculated using the Hertz-Sneddon model. For comparison, a numerical model for the indentation method is established using the finite element method. The difference between the actual modulus and the measured modulus is discussed. The effect of the thickness of the specimen on the measurement is investigated. Young＇s moduli of beef, porcine liver and porcine kidney are experimentally measured. The results indicate that our elastometer is effective in measuring Young＇s modulus of a soft tissue quantitatively.
基金supported by the National Natural Science Foundation of China(11104044)Science and Technology Foundation of State Key Laboratory(9140C200103110C20)the Key Project of NationalNatural Science Foundation(11234002)
文摘A measurement scheme carried out in a tank is designed to obtain the compressionaland shear-wave velocities of a large elastic material.A hydrophone is used to receive the high frequency acoustic signals which penetrate the tested material,in order to determine the transmission time from the source to the hydrophone,the transmission time is also calculated according to the ray acoustic theory in layered media.A cost function is built based on the measured and the calculated transmission time,then the compressional- and shear-wave velocities can be obtained using the optimization algorithm.Compared with the traditional measurement scheme,this approach can not only get the 2 kinds of sound velocities in the tested material at the same time,but also keep the integrality of the tested material.With the proposed measurement system,the uncertainty of measurement results is less than 3.5%.
