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Simulation of Natural Convection Flow with Magneto-Hydrodynamics in a Wavy Top Enclosure with a Semi-Circular Heater
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作者 Mohammad Mahfuzul Islam Md. Abdul Alim +1 位作者 Md. Mahmud Alam Md. Jahirul Haque Munshi 《Open Journal of Applied Sciences》 CAS 2023年第4期591-603,共13页
Natural convection flow in enclosure has different applications such as room ventilation, heat exchangers, the cooling system of a building etc. The Finite-Element method based on the Galerkin weighted residual approa... Natural convection flow in enclosure has different applications such as room ventilation, heat exchangers, the cooling system of a building etc. The Finite-Element method based on the Galerkin weighted residual approach is used to solve two-dimensional governing mass, momentum and energy-equations for natural convection flow in the presence of a magnetic field on a roof top with semi-circular heater. In the enclosure the horizontal lower wall was heated, the vertical two walls were adiabatic, inside the semi-circular heater, the wavy top wall cooled. The parameters Rayleigh number, Hartmann number and Prandtl number are considered. The effects of the Hartmann number and Rayleigh number on the streamlines, isotherms, velocity profiles and average Nusselt number are examined graphically. The local Nusselt number and the average Nusselt number of the heated portion of the enclosure with the semi-circular heater are presented in this paper. Finally, for the validation of the existing work, the current results are compared with published results and the auspicious agreement is achieved. 展开更多
关键词 Natural Convection magneto-hydrodynamics (MHD) Finite Element Method (FEM) Wavy Enclosure Semi-Circular Heater
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Research on the Development of Fibroin and Nano-Fiber from Silk Cocoons for Regenerated Tissue Engineering Applications by Electro-Spinning
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作者 Md Kamrul Hasan Xinbo Ding 《Advances in Nanoparticles》 CAS 2024年第1期1-9,共9页
In this paper, the main goal is to prepare silk fibroin nano-fiber, which is used for regenerated tissue applications. Silk scaffold nano-fibers made by electro-spinning technology can be used in regenerated tissue ap... In this paper, the main goal is to prepare silk fibroin nano-fiber, which is used for regenerated tissue applications. Silk scaffold nano-fibers made by electro-spinning technology can be used in regenerated tissue applications. The purpose of the research is to prepare a silk-fibroin nano-fiber solution for potential applications in tissue engineering. Using a degumming process, pure silk fibroin protein is extracted from silk cocoons. The protein solution for fibroin is purified, and the protein content is determined. The precise chemical composition, exact temperature, time, voltage, distance, ratio, and humidity all have a huge impact on degumming, solubility, and electro-spinning nano-fibers. The SEM investigates the morphology of silk fibroin nano-fibres at different magnifications. It also reveals the surface condition, fiber orientation, and fiber thickness of the silk fibroin nano-fiber. The results show that regenerated silk fibroin and nano-fiber can be used in silk fibroin scaffolds for various tissue engineering applications. 展开更多
关键词 Silk fibroin SCAFFOLD electro-spinning nano-fiber Tissue Engineering
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Preclinical Verification of Modulated Electro-Hyperthermia —Part I. In Vitro Research
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作者 Andras Szasz 《International Journal of Clinical Medicine》 CAS 2024年第7期257-298,共42页
Modulated electro-hyperthermia (mEHT) targets tissue’s natural electric and thermal heterogeneities to heat the cancer cells selectively. The applied 13.56 MHz radiofrequency (RF) is a carrier of the low-frequency mo... Modulated electro-hyperthermia (mEHT) targets tissue’s natural electric and thermal heterogeneities to heat the cancer cells selectively. The applied 13.56 MHz radiofrequency (RF) is a carrier of the low-frequency modulation. The high-frequency part was chosen to select the malignant lesion using the specialties of the tumor: the higher conductivity and dielectric constant of the tumor than its host. The electric field selects the tumor, and the low-frequency amplitude modulation polarizes and excites the transmembrane proteins of the malignant cells. The dominant absorption of the energy by the microscopic clusters of the membrane rafts acts like nanoparticle heating. Exciting the membrane produces various apoptotic signals. The processes were modeled using silico and phantom experiments, which proved the concept. The preclinical verification was made in vitro and in vivo, and in the end, clinical proofs validated the method. Our objective is to follow all the development steps from the laboratory to the clinics in a trilogy of articles. This present is the first part, which deals with in silico, phantom, and in vitro research. 展开更多
关键词 Modulated electro-Hyperthermia mEHT In Silico Calculations Phantom Measurement In Vitro Experiments Thermal Effects Nonthermal Processes Apoptosis
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Multiscale Finite Element Method for Coupling Analysis of Heterogeneous Magneto-Electro-Elastic Structures in Thermal Environment
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作者 Xinyue Li Xiaolin Li Hangran Yang 《Journal of Applied Mathematics and Physics》 2024年第9期3099-3113,共15页
Magneto-electro-elastic (MEE) materials, a new type of composite intelligent materials, exhibit excellent multifield coupling effects. Due to the heterogeneity of the materials, it is challenging to use the traditiona... Magneto-electro-elastic (MEE) materials, a new type of composite intelligent materials, exhibit excellent multifield coupling effects. Due to the heterogeneity of the materials, it is challenging to use the traditional finite element method (FEM) for mechanical analysis. Additionally, the MEE materials are often in a complex service environment, especially under the influence of the thermal field with thermoelectric and thermomagnetic effects, which affect its mechanical properties. Therefore, this paper proposes the efficient multiscale computational method for the multifield coupling problem of heterogeneous MEE structures under the thermal environment. The method constructs a multi-physics field with numerical base functions (the displacement, electric potential, and magnetic potential multiscale base functions). It equates a single cell of heterogeneous MEE materials to a macroscopic unit and supplements the macroscopic model with a microscopic model. This allows the problem to be solved directly on a macroscopic scale. Finally, the numerical simulation results demonstrate that compared with the traditional FEM, the multiscale finite element method (MsFEM) can achieve the purpose of ensuring accuracy and reducing the degree of freedom, and significantly improving the calculation efficiency. 展开更多
关键词 Multiscale Finite Element Method MAGNETO-electro-ELASTIC Multifield Coupling Numerical Base Functions
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Magneto-hydrodynamic flow of squeezed fluid with binary chemical reaction and activation energy 被引量:2
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作者 S.AHMAD M.FAROOQ +2 位作者 N.A.MIR Aisha ANJUM M.JAVED 《Journal of Central South University》 SCIE EI CAS CSCD 2019年第5期1362-1373,共12页
The present exploration is conducted to describe the motion of viscous fluid embedded in squeezed channel under the applied magnetics effects.The processes of heat and mass transport incorporate the temperature-depend... The present exploration is conducted to describe the motion of viscous fluid embedded in squeezed channel under the applied magnetics effects.The processes of heat and mass transport incorporate the temperature-dependent binary chemical reaction with modified Arrhenius theory of activation energy function which is not yet disclosed for squeezing flow mechanism.The flow,heat and mass regime are exposed to be governed via dimensionless,highly non-linear,ordinary differential equations (ODEs) under no-slip walls boundary conditions.A well-tempered analytical convergent procedure is adopted for the solutions of boundary value problem.A detailed study is accounted through graphs in the form of flow velocity field,temperature and fluid concentration distributions for various emerging parameters of enormous interest.Skin-friction,Nusselt and Sherwood numbers have been acquired and disclosed through plots.The results indicate that fluid temperature follows an increasing trend with dominant dimensionless reaction rate σ and activation energy parameter E.However,an increment in σ and E parameters is found to decline in fluid concentration.The current study arises numerous engineering and industrial processes including polymer industry,compression and injection shaping,lubrication system,formation of paper sheets,thin fiber,molding of plastic sheets.In the area of chemical engineering,geothermal engineering,cooling of nuclear reacting,nuclear or chemical system,bimolecular reactions,biochemical process and electrically conducting polymeric flows can be controlled by utilizing magnetic fields.Motivated by such applications,the proposed study has been developed. 展开更多
关键词 squeezing flow magneto-hydrodynamics (MHD) activation energy binary chemical reaction
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LOGARITHMICALLY IMPROVED REGULARITY CRITERION FOR THE 3D GENERALIZED MAGNETO-HYDRODYNAMIC EQUATIONS 被引量:1
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作者 赵继红 刘桥 《Acta Mathematica Scientia》 SCIE CSCD 2014年第2期568-574,共7页
This article proves the logarithmically improved Serrin's criterion for solutions of the 3D generalized magneto-hydrodynamic equations in terms of the gradient of the velocity field, which can be regarded as improvem... This article proves the logarithmically improved Serrin's criterion for solutions of the 3D generalized magneto-hydrodynamic equations in terms of the gradient of the velocity field, which can be regarded as improvement of results in [10] (Luo Y W. On the regularity of generalized MHD equations. J Math Anal Appl, 2010, 365: 806-808) and [18] (Zhang Z J. Remarks on the regularity criteria for generalized MHD equations. J Math Anal Appl, 2011, 375:799 802). 展开更多
关键词 Generalized magneto-hydrodynamic equations regularity criterion multiplier spaces
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三维Magneto-Hydrodynamics方程关于压强的正则准则
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作者 张静 《合肥学院学报(自然科学版)》 2014年第1期1-6,共6页
通过Navier-Stokes方程以及利用光滑解的先验估计方法,来探讨三维MHD方程的压强在Besov空间B·r!,!(R3)中的弱解正则准则.证明了当压强π(t)满足:π(t)∈L22+r(0,T;B·r!,!(R3)),-1≤r≤1此条件时,则三维MHD方程的一组弱解(v(x,... 通过Navier-Stokes方程以及利用光滑解的先验估计方法,来探讨三维MHD方程的压强在Besov空间B·r!,!(R3)中的弱解正则准则.证明了当压强π(t)满足:π(t)∈L22+r(0,T;B·r!,!(R3)),-1≤r≤1此条件时,则三维MHD方程的一组弱解(v(x,t),b(x,t))在(0,T]上是正则解. 展开更多
关键词 magneto-hydrodynamics方程 正则准则 压强 BESOV空间
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WELL-POSEDNESS AND STABILITY FOR THE GENERALIZED INCOMPRESSIBLE MAGNETO-HYDRODYNAMIC EQUATIONS IN CRITICAL FOURIER-BESOV-MORREY SPACES
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作者 Azzeddine EL BARAKA Mohamed TOUMLILIN 《Acta Mathematica Scientia》 SCIE CSCD 2019年第6期1551-1567,共17页
This paper concerns the Cauchy problem of the 3D generalized incompressible magneto-hydrodynamic(GMHD) equations. By using the Fourier localization argument and the Littlewood-Paley theory, we get local well-posedness... This paper concerns the Cauchy problem of the 3D generalized incompressible magneto-hydrodynamic(GMHD) equations. By using the Fourier localization argument and the Littlewood-Paley theory, we get local well-posedness results of the GMHD equations with large initial data(u0, b0) belonging to the critical Fourier-Besov-Morrey spaces FN^1-2α+3/p'+λ/pp,λ,q(R^3) Moreover, stability of global solutions is also discussed. 展开更多
关键词 magneto-hydrodynamic Fourier-Besov-Morrey space STABILITY
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Adaptive Grids in Simulations of Toroidal Plasma Starting from Magneto-Hydrodynamic Equilibrium
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作者 李旭静 L.E.ZAKHAROV S.A.GALKIN 《Plasma Science and Technology》 SCIE EI CAS CSCD 2015年第2期97-104,共8页
This paper introduces the notion of Tokamak Magneto-Hydrodynamics (TMHD), which explicitly reflects the anisotropy of a high temperature tokamak plasma. The set of TMHD equations is formulated for simulation of macr... This paper introduces the notion of Tokamak Magneto-Hydrodynamics (TMHD), which explicitly reflects the anisotropy of a high temperature tokamak plasma. The set of TMHD equations is formulated for simulation of macroscopic plasma dynamics and disruptions in tokamaks. Free from the Courant restriction on the time step, this set of equations is adequate to plasma dynamics with realistic parameters of high performance plasmas and does not require any extension of the MHD plasma model. At the same time, TMHD requires the use of magnetic field aligned numerical grids. Examples of their use in 2-dimensional cases of tokamak equilibria and dynamics of the wall touching kink mode are presented. For the 3-dimensional case of an ergodic magnetic field, this paper introduces the reference magnetic coordinates as a practical algorithm for generating adaptive grids for TMHD. 展开更多
关键词 TOKAMAK magneto-hydrodynamicS DISRUPTIONS numerical simulations adaprive grid
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Noncovalent interactions on the electrocatalytic oxidation of ethanol on a Pt/C electrocatalyst 被引量:1
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作者 Chenjie Han Yeqing Lyu +4 位作者 Shaona Wang Biao Liu Yi Zhang Jun Lu Hao Du 《Carbon Energy》 SCIE EI CAS CSCD 2023年第9期113-123,共11页
Due to their environmentally friendly nature and high energy density,direct ethanol fuel cells have attracted extensive research attention in recent decades.However,the actual Faraday efficiency of the ethanol oxidati... Due to their environmentally friendly nature and high energy density,direct ethanol fuel cells have attracted extensive research attention in recent decades.However,the actual Faraday efficiency of the ethanol oxidation reaction(EOR)is much lower than its theoretical value and the reaction kinetics of the EOR is sluggish due to insufficient active sites on the electrocatalyst surface.Pt/C is recognized as one of the most promising electrocatalysts for the EOR.Thus,the microscopic interfacial reaction mechanisms of the EOR on Pt/C were systematically studied in this work.In metal hydroxide solutions,hydrated alkali cations were found to bind with OH_(ad)through noncovalent interactions to form clusters and occupy the active sites on the Pt/C electrocatalyst surface,thus resulting in low Faraday efficiency and sluggish kinetics of the EOR.To reduce the negative effect of the noncovalent interactions on the EOR,a shield was made on the electrocatalyst surface using 4-trifluoromethylphenyl,resulting in twice the EOR catalytic reactivity of Pt/C. 展开更多
关键词 ethanol electro‐oxidation Faraday efficiency KINETICS modification of electrocatalyst noncovalent interactions
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Approximate solution of the flow over a nonlinear magneto-hydrodynamic stretching sheet
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《Chinese Physics B》 SCIE EI CAS CSCD 2012年第3期310-313,共4页
The approximate solution of the magneto-hydrodynamic (MHD) boundary layer flow over a nonlinear stretching sheet is obtained by combining the Lie symmetry method with the homotopy perturbation method. The approximat... The approximate solution of the magneto-hydrodynamic (MHD) boundary layer flow over a nonlinear stretching sheet is obtained by combining the Lie symmetry method with the homotopy perturbation method. The approximate solution is tabulated, plotted for the values of various parameters and compared with the known solutions. It is found that the approximate solution agrees very well with the known numerical solutions, showing the reliability and validity of the present work. 展开更多
关键词 magneto-hydrodynamic (MHD) boundary layer flow Lie symmetry method homotopy perturbation method approximate solution
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Improved Electro Search Algorithm with Intelligent Controller Control System:ESPID Algorithm
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作者 Inayet Hakki Cizmeci Adem Alpaslan Altun 《Intelligent Automation & Soft Computing》 SCIE 2023年第3期2555-2572,共18页
Studies have established that hybrid models outperform single models.The particle swarm algorithm(PSO)-based PID(proportional-integral-derivative)controller control system is used in this study to determine the parame... Studies have established that hybrid models outperform single models.The particle swarm algorithm(PSO)-based PID(proportional-integral-derivative)controller control system is used in this study to determine the parameters that directly impact the speed and performance of the Electro Search(ESO)algorithm to obtain the global optimum point.ESPID algorithm was created by integrating this system with the ESO algorithm.The improved ESPID algorithm has been applied to 7 multi-modal benchmark test functions.The acquired results were compared to those derived using the ESO,PSO,Atom Search Optimization(ASO),and Vector Space Model(VSM)algorithms.As a consequence,it was determined that the ESPID algorithm’s mean score was superior in all functions.Additionally,while comparing the mean duration value and standard deviations,it is observed that it is faster than the ESO algorithm and produces more accurate results than other algorithms.ESPID algorithm has been used for the least cost problem in the production of pressure vessels,which is one of the real-life pro-blems.Statistical results were compared with ESO,Genetic algorithm and ASO.ESPID was found to be superior to other methods with the least production cost value of 5885.452. 展开更多
关键词 electro search algorithm intelligent PID optimization multi-optimization
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The decisive role of adsorbed OH^(*)in low‐potential CO electro‐oxidation on single‐atom catalytic sites
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作者 Yang Li Xian Wang +7 位作者 Ying Wang Zhaoping Shi Yuqi Yang Tuo Zhao Zheng Jiang Changpeng Liu Wei Xing Junjie Ge 《Carbon Energy》 SCIE EI CAS CSCD 2023年第9期63-73,共11页
CO impurity-induced catalyst deactivation has long been one of the biggest challenges in proton-exchange membrane fuel cells,with the poisoning phenomenon mainly attributed to the overly strong adsorption on the catal... CO impurity-induced catalyst deactivation has long been one of the biggest challenges in proton-exchange membrane fuel cells,with the poisoning phenomenon mainly attributed to the overly strong adsorption on the catalytic site.Here,we present a mechanistic study that overturns this understanding by using Rh-based single-atom catalysis centers as model catalysts.We precisely modulated the chelation structure of the Rh catalyst by coordinating Rh with C or N atoms,and probed the reaction mechanism by surface-enhanced Raman spectroscopy.Direct spectroscopic evidence for intermediates indicates that the reactivity of adsorbed OH^(*),rather than the adsorption strength of CO^(*),dictates the CO electrocatalytic oxidation behavior.The RhN_(4)sites,which adsorb the OH^(*)intermediate more weakly than RhC4 sites,showed prominent CO oxidation activity that not only far exceeded the traditional Pt/C but also the RhC4 sites with similar CO adsorption strength.From this study,it is clear that a paradigm shift in future research should be considered to rationally design high-performance CO electro-oxidation reaction catalysts by sufficiently considering the water-related reaction intermediate during catalysis. 展开更多
关键词 adsorbed CO^(*)and OH^(*) carbon‐based Rh single‐atom catalysts CO electro‐oxidation reaction electron interaction MNx moiety
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滚仰式光电吊舱地理导引实现与误差分析 被引量:1
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作者 董期林 张卫国 +5 位作者 赵创社 王超 袁屹杰 伊兴国 刘万刚 程勇栋 《中国光学(中英文)》 EI CAS CSCD 北大核心 2024年第3期630-639,共10页
为了提升地理导引精度和成功率,根据滚仰式光电吊舱的结构特点,通过建立坐标系统、目标坐标求解和框架角解算三个步骤,完整构建了地理导引的数学模型,并在此基础上引入了速度前馈和小区域搜索模式。同时,对受惯导测量误差和目标距离影... 为了提升地理导引精度和成功率,根据滚仰式光电吊舱的结构特点,通过建立坐标系统、目标坐标求解和框架角解算三个步骤,完整构建了地理导引的数学模型,并在此基础上引入了速度前馈和小区域搜索模式。同时,对受惯导测量误差和目标距离影响的框架角解算误差进行了数据仿真。结果表明:经纬误差和航向角误差对俯仰角的解算误差影响较大;而高程误差和水平姿态角误差则对横滚角的解算误差影响较大。提升惯导的定位精度,可进一步减小框架角解算误差,从而提升地理导引精度,而当航向角<0.1°,水平姿态角<0.05°时,姿态角误差的影响权重会变小,再通过减小姿态角误差提升导引精度的作用已不明显。随着目标距离的增大,框架角解算误差会急剧减小。最后进行了导引试验,其俯仰、横滚角均方差均小于0.12°,表明了算法的准确性和仿真分析的有效性。 展开更多
关键词 滚仰式光电吊舱 地理导引 坐标转换 误差分析
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基于DDS的数字脉冲电火花沉积电源研究 被引量:1
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作者 刘宇 高洋 +3 位作者 张诗奇 杜姗 张生芳 王紫光 《电加工与模具》 北大核心 2024年第1期26-30,51,共6页
在电火花沉积加工中,脉冲电源的放电参数对沉积效果和加工效率有重要影响。针对传统电火花沉积电源放电参数可控性差的问题,基于直接数字频率合成(DDS)技术全数字化调制、输出稳定的特性,设计了一种数字脉冲电火花沉积电源。以单片机和... 在电火花沉积加工中,脉冲电源的放电参数对沉积效果和加工效率有重要影响。针对传统电火花沉积电源放电参数可控性差的问题,基于直接数字频率合成(DDS)技术全数字化调制、输出稳定的特性,设计了一种数字脉冲电火花沉积电源。以单片机和DDS芯片为核心来控制斩波电路输出加工脉冲,可实现放电电压、频率等参数的较精确控制以及宽范围内的无极调节。经测试,控制及驱动模块输出信号稳定、准确且频率误差在1 Hz以内,放电电压波形可控性好,满足电火花沉积加工的要求,可用于电火花沉积加工基础研究。 展开更多
关键词 电火花沉积 DDS技术 脉冲电源 可控性
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三维Electro-Hydrodynamics方程组光滑解的延拓准则
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作者 吴繁 《南昌工程学院学报》 CAS 2023年第6期93-98,共6页
研究了三维Electro-Hydrodynamics方程组局部光滑解的延拓准则,利用负指标Besov空间中的对数Sobolev不等式和Kato-Ponce交换子估计方法,在Besov空间中获得了只涉及速度场水平分量的最优延拓准则,改进和推广了已有关于Electro-Hydrodynam... 研究了三维Electro-Hydrodynamics方程组局部光滑解的延拓准则,利用负指标Besov空间中的对数Sobolev不等式和Kato-Ponce交换子估计方法,在Besov空间中获得了只涉及速度场水平分量的最优延拓准则,改进和推广了已有关于Electro-Hydrodynamics方程组正则性准则的部分结论,是Electro-Hydrodynamics方程组正则性理论的有益补充。 展开更多
关键词 electro-Hydronamics方程 延拓准则 BESOV空间
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BDD电催化耦合电解析处理载人航天器中冷凝废水的研究
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作者 王传增 周文兴 +3 位作者 余青霓 魏巍 卞强 杨润泽 《载人航天》 CSCD 北大核心 2024年第2期174-182,共9页
为解决在硼掺杂的金刚石电极(BDD)电催化处理冷凝废水中,由于冷凝废水电导率低而导致处理能耗较高的问题,提出了BDD电催化耦合电解析的新方法处理冷凝废水。在BDD反应器内填充吸附有无机盐的混合阴阳离子交换树脂,电催化处理冷凝废水时... 为解决在硼掺杂的金刚石电极(BDD)电催化处理冷凝废水中,由于冷凝废水电导率低而导致处理能耗较高的问题,提出了BDD电催化耦合电解析的新方法处理冷凝废水。在BDD反应器内填充吸附有无机盐的混合阴阳离子交换树脂,电催化处理冷凝废水时吸附在树脂上的离子在电场作用下解析下来进入废水中,并进行交替的吸附、解析及定向运动,从而改善废水的导电性,电极两端电压显著降低,停止加电后,离子又能重新交换吸附在树脂上。以Na_(2)SO_(4),Na_(3)PO_(4)以及NaNO_(3)作为电解质时,对总有机碳(TOC)去除没有影响;而以NaCl作为电解质时,TOC去除率随着NaCl添加量的增加而降低。 展开更多
关键词 冷凝废水 BDD 电催化耦合电解析 离子交换
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负载型三维电极-电Fenton法处理活性艳橙X-GN废水 被引量:1
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作者 李亚峰 许嗣鼎 +1 位作者 高崇 傅翔宇 《工业水处理》 CSCD 北大核心 2024年第1期80-87,共8页
三维电极-电Fenton法是一种在电Fenton的基础上引入三维电极电催化技术的新型高级氧化法,在水处理中得到了广泛的应用。用过量浸渍煅烧法制备负载型三维电极,以采用该电极的三维电极-Fenton法处理活性艳橙X-GN废水。通过试验研究了pH、... 三维电极-电Fenton法是一种在电Fenton的基础上引入三维电极电催化技术的新型高级氧化法,在水处理中得到了广泛的应用。用过量浸渍煅烧法制备负载型三维电极,以采用该电极的三维电极-Fenton法处理活性艳橙X-GN废水。通过试验研究了pH、电压、Na_(2)SO_(4)投加量、Fe^(2+)投加量对处理效果的影响,并采用响应曲面法最优化实验条件。结果表明,当试验pH=4.7,电压为20.39 V,Na_(2)SO_(4)投加量为2.13 g/L,Fe^(2+)投加量为2.5 mmol/L时,COD和色度去除率可以达到85.41%和92.18%。负载型三维电极-电Fenton法对活性艳橙X-GN废水的色度和COD均具有较理想的处理效果。 展开更多
关键词 三维电极 电FENTON 印染废水 电催化
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电针对硝酸甘油致偏头痛小鼠疼痛行为及三叉神经血管系统的影响
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作者 徐晓白 张若滔 +8 位作者 王雪飞 温雅丽 王握瑜 刘璐 赵洛鹏 李志娟 王麟鹏 郭静 李彬 《现代中西医结合杂志》 CAS 2024年第3期293-298,305,共7页
目的观察电针对硝酸甘油致偏头痛小鼠疼痛行为及三叉神经血管功能的影响,探讨其可能作用机制。方法将20只C57BL/6雄性小鼠随机分为对照组、模型组、假针组、电针组,每组5只。除对照组外,其余组小鼠于实验第1,3,5,7,9,11,13天给予10 mg/k... 目的观察电针对硝酸甘油致偏头痛小鼠疼痛行为及三叉神经血管功能的影响,探讨其可能作用机制。方法将20只C57BL/6雄性小鼠随机分为对照组、模型组、假针组、电针组,每组5只。除对照组外,其余组小鼠于实验第1,3,5,7,9,11,13天给予10 mg/kg硝酸甘油腹腔注射建立慢性偏头痛模型。在每次注射后30 min,电针组和假针组进行电针干预。实验当天(第0天)注射前及实验第2,4,6,8,10,12,14天分别检测小鼠眶周机械痛阈及后足机械痛阈、热痛痛阈;实验第14天,采用ELISA法检测血清一氧化氮(NO)和降钙素基因相关肽(CGRP)水平,采用免疫荧光和Western blot法检测三叉神经节中c-Fos蛋白表达情况。结果实验第6,8,10,12,14天,模型组小鼠的眶周机械刺激反应评分均明显高于同期对照组(P均<0.05);实验第10,12,14天,电针组小鼠的眶周机械刺激反应评分均明显低于同期模型组(P均<0.05),且电针组小鼠实验第12,14天的眶周机械刺激反应评分均明显低于同期假针组(P均<0.05)。实验第8,10,12,14天,模型组小鼠的后足50%撤退阈值均明显低于同期对照组(P均<0.05),后足热痛撤退潜伏期均明显短于同期对照组(P均<0.05);实验第10,12,14天,电针组小鼠的后足50%撤退阈值均明显高于同期模型组(P均<0.05),后足热痛撤退潜伏期均明显长于同期模型组(P均<0.05),且电针组小鼠实验第12,14天的后足50%撤退阈值明显高于同期假针组(P均<0.05),后足热痛撤退潜伏期均明显长于同期假针组(P均<0.05)。模型组小鼠血清NO、CGRP水平和三叉神经节中c-Fos阳性表达平均光密度、c-Fos蛋白相对表达量均明显高于对照组(P均<0.05),而电针组各指标均明显低于模型组(P均<0.05)。结论电针能明显改善硝酸甘油致慢性偏头痛小鼠的疼痛行为,其可能是通过降低血清NO、CGRP水平及三叉神经敏化蛋白c-Fos的表达,从而改善三叉神经血管功能障碍实现的。 展开更多
关键词 偏头痛 硝酸甘油 电针 三叉神经血管系统
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环境化学条件对软土电渗排水影响的试验研究
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作者 张林 胡黎明 《水力发电学报》 CSCD 北大核心 2024年第6期33-42,共10页
电渗排水在软土地基加固方面具有较大的应用前景。为研究土体环境化学条件对软黏土电渗排水过程的影响,开展了一系列室内试验,从电渗系数、排水量、排水速率、含水率分布等方面进行了对比分析,深入探讨土体pH值和盐度对电渗排水过程的... 电渗排水在软土地基加固方面具有较大的应用前景。为研究土体环境化学条件对软黏土电渗排水过程的影响,开展了一系列室内试验,从电渗系数、排水量、排水速率、含水率分布等方面进行了对比分析,深入探讨土体pH值和盐度对电渗排水过程的影响机理。试验结果表明:土体pH值对土体的电渗系数和zeta电位均有明显影响,电渗系数随着pH值的升高而升高,通过测量zeta电位可以准确获取电渗系数;随着土体初始pH值的升高,电渗排水试验后阳极附近土体的含水率逐渐降低,阴极附近土体的含水率逐渐升高;在对较酸性土体的电渗试验中则出现了阴极附近土体排水固结较快的现象,对土体的整体排水过程产生不利影响;随着土体盐度的升高,电渗系数和电渗总排水量降低,能耗增大。低盐度、偏碱性的环境有利于提高电渗加固效果。 展开更多
关键词 电渗加固 电渗系数 土体pH值 土体盐度 软土
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