Objective: To study the efficacy of electrolyzed oxidizing water ( EOW ) and hydrocolloid occlusive dressings in the acceleration of epithelialization in excised burn-wounds in rats.Methods: Each of the anesthetized S...Objective: To study the efficacy of electrolyzed oxidizing water ( EOW ) and hydrocolloid occlusive dressings in the acceleration of epithelialization in excised burn-wounds in rats.Methods: Each of the anesthetized Sprague-Dawley rats (n = 28) was subjected to a third-degree burn that covered approximately 10% of the total body surface area. Rats were assigned into four groups: Group Ⅰ ( no irrigation), Group Ⅱ (irrigation with physiologic saline), Group Ⅲ ( irrigation with EOW ) and Group Ⅳ ( hydrocolloid occlusive dressing after EOW irrigation). Wounds were observed macroscopically until complete epithelialization was present, then the epithelialized wounds were examined microscopically. Results: Healing of the burn wounds was the fastest in Group Ⅳ treated with hydrocolloid occlusive dressing together with EOW. Although extensive regenerative epidermis was seen in each Group, the proliferations of lymphocytes and macrophages associated with dense collagen deposition were more extensive in Group Ⅱ, Ⅲ and IV than in Group Ⅰ. These findings were particularly evident in Group Ⅲ and Ⅳ.Conclusions: Wound Healing may be accelerated by applying a hydrocolloid occlusive dressing on burn surfaces after they are cleaned with EOW.展开更多
研究了4种单独杀菌工艺和2种组合杀菌工艺。结果表明,在肉水质量比为1∶4时,酸性氧化电位水表面处理工艺对肉糜的杀灭对数值为2.72 lg CFU/g,酸性氧化电位水表面处理+碱性还原电位水混合处理的杀菌对数值为3.14 lg CFU/g。随着酸性氧化...研究了4种单独杀菌工艺和2种组合杀菌工艺。结果表明,在肉水质量比为1∶4时,酸性氧化电位水表面处理工艺对肉糜的杀灭对数值为2.72 lg CFU/g,酸性氧化电位水表面处理+碱性还原电位水混合处理的杀菌对数值为3.14 lg CFU/g。随着酸性氧化电位水用量增加,2种工艺的杀菌效果均提高;酸性氧化电位水和肉糜接触1 min后氧化电位值迅速由1 132 mV降至935 mV,有效氯由78.60 mg/L降至47.35 mg/L。另外,酸性氧化电位水对肉糜有很好的抑菌作用。通过研究酸性氧化电位水、碱性还原电位水、HCl、NaOH和NaClO对大肠杆菌和枯草杆菌黑色变种芽孢悬液的杀菌效果表明,酸性氧化电位水杀菌效率最高,电位水中有效的杀菌因素是有效氯和氧化还原电位值。展开更多
基金This study was supported by the Ministry of Education, Science,Sports and Culture of Japan(No.10470311).
文摘Objective: To study the efficacy of electrolyzed oxidizing water ( EOW ) and hydrocolloid occlusive dressings in the acceleration of epithelialization in excised burn-wounds in rats.Methods: Each of the anesthetized Sprague-Dawley rats (n = 28) was subjected to a third-degree burn that covered approximately 10% of the total body surface area. Rats were assigned into four groups: Group Ⅰ ( no irrigation), Group Ⅱ (irrigation with physiologic saline), Group Ⅲ ( irrigation with EOW ) and Group Ⅳ ( hydrocolloid occlusive dressing after EOW irrigation). Wounds were observed macroscopically until complete epithelialization was present, then the epithelialized wounds were examined microscopically. Results: Healing of the burn wounds was the fastest in Group Ⅳ treated with hydrocolloid occlusive dressing together with EOW. Although extensive regenerative epidermis was seen in each Group, the proliferations of lymphocytes and macrophages associated with dense collagen deposition were more extensive in Group Ⅱ, Ⅲ and IV than in Group Ⅰ. These findings were particularly evident in Group Ⅲ and Ⅳ.Conclusions: Wound Healing may be accelerated by applying a hydrocolloid occlusive dressing on burn surfaces after they are cleaned with EOW.
