A new method for the rapid separation of gangliosides(GLS)by capillary electrophoresis(CE)is described which is based on the use of β—cyclodextrin(β—CD)as buffer additive.The effects of β—CD concentration,pH,ele...A new method for the rapid separation of gangliosides(GLS)by capillary electrophoresis(CE)is described which is based on the use of β—cyclodextrin(β—CD)as buffer additive.The effects of β—CD concentration,pH,electrolyte composition were dis- cussed.Under optimum conditions,the complete separation of a mixture of GM1,GD1a, GD1b and GT1b was obtained within 5 min.展开更多
文摘A new method for the rapid separation of gangliosides(GLS)by capillary electrophoresis(CE)is described which is based on the use of β—cyclodextrin(β—CD)as buffer additive.The effects of β—CD concentration,pH,electrolyte composition were dis- cussed.Under optimum conditions,the complete separation of a mixture of GM1,GD1a, GD1b and GT1b was obtained within 5 min.