Biological activity dressings on wound healing consist of Prionace glauca cartilage type Ⅱ collagen( CII) cartilage,chitosan and polyethylene oxide( PEO). The dressing fibers are successfully obtained by electrospinn...Biological activity dressings on wound healing consist of Prionace glauca cartilage type Ⅱ collagen( CII) cartilage,chitosan and polyethylene oxide( PEO). The dressing fibers are successfully obtained by electrospinning from the acetic acid aqueous solution( 80%, volume fraction). An effective quadric polynomial regression model,including the feed speed( m L/h),the applied voltage( kV) and the nozzle-collector distance( cm),was set up by response surface methodology. By using the optimized process parameters( applied voltage 20 kV,nozzle-collector distance 16. 6 cm and feed speed 0. 70 m L/h),the mean diameter( 230. 34 nm) was reduced by about 10% compared with the original one.展开更多
For obtaining high-throughput production of nanofibers,the preparation mechanism of a self-made spherical section free surface electrospinning(SSFSE)using solution reservoirs with different depths was studied.The effe...For obtaining high-throughput production of nanofibers,the preparation mechanism of a self-made spherical section free surface electrospinning(SSFSE)using solution reservoirs with different depths was studied.The effects of the solution res-ervoir depth on the SSFSE process as well as the quality and yield of polyacrylonitrile(PAN)nanofibers were investigated experimentally using high-speed camera,precise electronic balance and scanning electron microscopy.Furthermore,the results were analyzed theoretically by response surface methodology(RSM)and numerical simulation.The values predicted by the established RSM model and the electric field results obtained by Maxwell 3D were all consistent with the experimental data,which showed that the different depths of the solution reservoir had little effect on the quality of PAN nanofibers,but had great effects on the yields of them.The PAN nanofibers prepared have the best quality and the highest yields when the maximum depth of the solution reservoir was 4.29 mm.展开更多
基金National Science and Technology Major Project of the Ministry of Science and Technology of China(No.2014ZX09J14103-09C-003)
文摘Biological activity dressings on wound healing consist of Prionace glauca cartilage type Ⅱ collagen( CII) cartilage,chitosan and polyethylene oxide( PEO). The dressing fibers are successfully obtained by electrospinning from the acetic acid aqueous solution( 80%, volume fraction). An effective quadric polynomial regression model,including the feed speed( m L/h),the applied voltage( kV) and the nozzle-collector distance( cm),was set up by response surface methodology. By using the optimized process parameters( applied voltage 20 kV,nozzle-collector distance 16. 6 cm and feed speed 0. 70 m L/h),the mean diameter( 230. 34 nm) was reduced by about 10% compared with the original one.
基金financially by National Natural Science Foundation of China(Grant No.11672198)Jiangsu Higher Education Institutions of China(Grant No.20KJA130001)+2 种基金Six Talent Peaks Project of Jiangsu Province(Grant No.GDZB-050)Science and Technology Guiding Project of China National Textile and Apparel Council(2020013)PAPD(A Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions).
文摘For obtaining high-throughput production of nanofibers,the preparation mechanism of a self-made spherical section free surface electrospinning(SSFSE)using solution reservoirs with different depths was studied.The effects of the solution res-ervoir depth on the SSFSE process as well as the quality and yield of polyacrylonitrile(PAN)nanofibers were investigated experimentally using high-speed camera,precise electronic balance and scanning electron microscopy.Furthermore,the results were analyzed theoretically by response surface methodology(RSM)and numerical simulation.The values predicted by the established RSM model and the electric field results obtained by Maxwell 3D were all consistent with the experimental data,which showed that the different depths of the solution reservoir had little effect on the quality of PAN nanofibers,but had great effects on the yields of them.The PAN nanofibers prepared have the best quality and the highest yields when the maximum depth of the solution reservoir was 4.29 mm.