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Anxiolytic property of hydro-alcohol extract of Lactuca sativa and its effect on behavioral activities of mice 被引量:4
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作者 Singapura Nagesh Harsha Kandangath Raghavan Anilakumar 《The Journal of Biomedical Research》 CAS 2013年第1期37-42,共6页
Lactuca sativa, belonging to the Asteraceae family, is a leafy vegetable known for its medicinal properties. This study aimed to understand the mechanism of Lactuca sativa extract with respect to pharmacological actio... Lactuca sativa, belonging to the Asteraceae family, is a leafy vegetable known for its medicinal properties. This study aimed to understand the mechanism of Lactuca sativa extract with respect to pharmacological action. We investigated the anxiolytic effects of hydro-alcoholic extract of leaves of Lactuca sativa on mice. The behav- ioral tests performed on mice models to assess anti-anxiety properties were: open field test (OFT), elevated plus maze test (EPM), elevated T maze test, and marble burying test. Increased locomotor activity and time spent in the "open-ann" were observed in extract fed group. Malondialdehyde (MDA) and nitrite levels were decreased, cata- lase and glutathione levels were increased in Lactuca sativa treated mice. The data obtained in the present study suggests that the extract of Lactuca sativa can afford significant protection against anxiolytic activity. 展开更多
关键词 Lactuca sativa ANXIETY NITRITE open field test (OFT) elevated plus maze test (EPM) malondialde-hyde (MDA)
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西藏水苏的抗焦虑活性(英文)
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作者 Dinesh Kumar Zulfiqar Ali Bhat +2 位作者 Vijender Kumar W Y Raja M.Y.Shah 《中国天然药物》 SCIE CAS CSCD 2013年第3期240-244,共5页
瞄准 S。tibetica Vatke 是在世界的热带、副热带的区域散布的植物,包括西藏,中国,和印度。在它在 Kargil 的冷荒芜的区域被发现的印度, Ladakh 山谷,并且在 Himachal Pradesh 的山脉。在 Kargil 和 Ladakh 的传统的专业人员为各... 瞄准 S。tibetica Vatke 是在世界的热带、副热带的区域散布的植物,包括西藏,中国,和印度。在它在 Kargil 的冷荒芜的区域被发现的印度, Ladakh 山谷,并且在 Himachal Pradesh 的山脉。在 Kargil 和 Ladakh 的传统的专业人员为各种各样的心理混乱和恐惧的处理使用自然的药 Stachys tibetica。现在的学习针对在老鼠评估根,茎,叶,和 Stachys tibetica Vatke 的整个工厂材料的 methanolic 摘录的 anxiolytic 效果。每植物部分的方法粉状的材料(1 kg ) 与甲醇(95%) 在一台 Soxhlet 仪器受到抽取;分别地产出 12.8% , 8.3% , 17.2% ,和 19.6% W/W extractives。摘录为他们用提高的正迷宫(EPM ) 的效果在老鼠测试的 anxiolytic 被评估。在礼品的结果学习, methanolic 提取,这被发现(200 和 400 mgred 到健康控制题目。方法 49 个病人(意味着年龄 41 他在 Cu-Zn-Zr 之中的协同作用将在 K-Cu/Zn/La/ZrO2 催化剂的活动有重要效果。锻烧温度什么时候是 450 污敵 ? 慷 ? 桴 ? 楨桧獥 ? 湯搠祡? 漠 ? 敲牦杩牥瑡摥猠潴慲敧椠 ?? 猠瑡癩浵昭獩 ? 潣汬条湥礭杯牵 ????? 牃湯慢档 ? 愠摮琠敨挠楲整楲湯爭汥瑡摥瘠污摩瑩 ? 景琠敨焠敵瑳潩湮楡敲眠獡攠慶畬瑡摥琠牨畯桧愠獳' 覒 X 楴湯?敢睴敥?桴?楤???訬? 訬 ?? 展开更多
关键词 Stachys tibetica Vatke Lamiaceae ANXIOLYTIC elevated plus maze test
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